Vivian Ruvolo

Vivian Ruvolo

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Vivian Ruvolo

Vivian Ruvolo

Publications by authors named "Vivian Ruvolo"

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LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML.

EBioMedicine 2019 Jun 16;44:126-137. Epub 2019 May 16.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Division of Molecular Hematology and Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604360PMC
June 2019

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.

Cancer Cell 2019 May 2;35(5):721-737.e9. Epub 2019 May 2.

The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA; The University of Texas MD Anderson Cancer Center; Department of Leukemia, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620028PMC
May 2019

An ARC-Regulated IL1β/Cox-2/PGE2/β-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML.

Cancer Res 2019 Mar 23;79(6):1165-1177. Epub 2019 Jan 23.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420856PMC
March 2019

Role of MSC-derived galectin 3 in the AML microenvironment.

Biochim Biophys Acta Mol Cell Res 2018 07 12;1865(7):959-969. Epub 2018 Apr 12.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Section of Molecular Hematology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.bbamcr.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936474PMC
July 2018

Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy.

Cancer Cell 2017 Dec;32(6):748-760.e6

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730338PMC
December 2017

Tumor status and genotype affect the bone marrow microenvironment in acute myeloid leukemia.

Oncotarget 2017 Oct 6;8(48):83354-83369. Epub 2017 Jul 6.

Department of Leukemia, Section of Molecular Hematology and Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.19042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663521PMC
October 2017

Focal Adhesion Kinase as a Potential Target in AML and MDS.

Mol Cancer Ther 2017 06 7;16(6):1133-1144. Epub 2017 Mar 7.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457713PMC
June 2017

MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation.

PLoS One 2015 6;10(10):e0139254. Epub 2015 Oct 6.

Section of Molecular Hematology and Therapy; Departments of Leukemia and Stem Cell Transplantation, UT MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139254PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595506PMC
June 2016

The Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations.

Cancer Res 2016 Mar 28;76(6):1528-37. Epub 2016 Jan 28.

Section of Molecular Hematology and Therapy, The University of Texas MD Anderson Cancer Center, Houston Texas. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794401PMC
March 2016

Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.

Br J Haematol 2014 Nov 31;167(3):376-84. Epub 2014 Jul 31.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1111/bjh.13054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357400PMC
November 2014

The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.

Biochim Biophys Acta 2014 Sep 21;1843(9):1969-77. Epub 2014 May 21.

Division of Molecular Hematology, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2014.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165504PMC
September 2014

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

Cancer Discov 2014 Mar 17;4(3):362-75. Epub 2013 Dec 17.

Departments of 1Leukemia, 2Pediatrics, and 3Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; 4Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; 5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 6The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio; 7AbbVie Inc., North Chicago, Illinois; and 8Department of Laboratory Medicine, University of California San Francisco, San Francisco, California; 9Department of Internal Medicine III, University Hospital of Ulm, Ulm; 10MLL Munich Leukemia Laboratory, Munich, Germany.

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http://research4.dfci.harvard.edu/letai/Publications/2013-12
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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975047PMC
March 2014

Prognostic impact and targeting of CRM1 in acute myeloid leukemia.

Blood 2013 May 5;121(20):4166-74. Epub 2013 Apr 5.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2012-08-447581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656451PMC
May 2013

Decreased sensitivity of 17p-deleted chronic lymphocytic leukemia cells to a small molecule BCL-2 antagonist ABT-737.

Cancer 2012 Feb 14;118(4):1023-31. Epub 2011 Jul 14.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/cncr.26360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579224PMC
February 2012

Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells.

J Signal Transduct 2010 Jan;2010:584657

Section of Signal Transduction and Apoptosis, Hormel Institute, University of Minnesota, Austin, MN 55912, USA.

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http://dx.doi.org/10.1155/2010/584657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938797PMC
January 2010

PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells.

J Biol Chem 2008 Dec 28;283(51):35474-85. Epub 2008 Oct 28.

Section of Signal Transduction and Apoptosis, University of Minnesota Hormel Institute, Austin, Minnesota 55912, USA.

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http://dx.doi.org/10.1074/jbc.M800951200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602900PMC
December 2008

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.

Nat Med 2007 Jun 21;13(6):730-5. Epub 2007 May 21.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nm1579DOI Listing
June 2007

The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

Cancer Res 2007 May;67(9):4210-8

Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3629DOI Listing
May 2007

Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.

Cancer Res 2007 Apr;67(7):3210-9

Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, M. D. Anderson Cancer Center, The University of Texas, Houston, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-2712DOI Listing
April 2007

PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.

Ann Hematol 2006 Oct 11;85(10):689-704. Epub 2006 Jul 11.

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas M D Anderson Cancer Center, 1400 Holcombe Boulevard, Unit 448, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s00277-006-0148-7DOI Listing
October 2006

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.

Blood 2005 Nov 12;106(9):3150-9. Epub 2005 Jul 12.

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Unit 448, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2005-02-0553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895324PMC
November 2005

Replication and packaging of Norwalk virus RNA in cultured mammalian cells.

Proc Natl Acad Sci U S A 2005 Jul 7;102(29):10327-32. Epub 2005 Jul 7.

Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.0408529102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177355PMC
July 2005

The Epstein-Barr virus SM protein induces STAT1 and interferon-stimulated gene expression.

J Virol 2003 Mar;77(6):3690-701

University of Florida Shands Cancer Center, University of Florida, Gainesville, Florida 32610-0232, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149524PMC
http://dx.doi.org/10.1128/jvi.77.6.3690-3701.2003DOI Listing
March 2003