Publications by authors named "Vittorio Rosti"

100Publications

Therapeutic Potential of Endothelial Colony-Forming Cells in Ischemic Disease: Strategies to Improve their Regenerative Efficacy.

Int J Mol Sci 2020 Oct 7;21(19). Epub 2020 Oct 7.

Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/ijms21197406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582994PMC
October 2020

Reduced CXCR4-expression on CD34-positive blood cells predicts outcomes of persons with primary myelofibrosis.

Leukemia 2020 Jun 14. Epub 2020 Jun 14.

Center for the Study of Myelofibrosis, Laboratory of Biochemistry, Biotechnology and Advanced Diagnostics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy.

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http://dx.doi.org/10.1038/s41375-020-0926-6DOI Listing
June 2020

Systemic lupus erythematosus, endothelial progenitor cells and intracellular Ca signaling: A novel approach for an old disease.

J Autoimmun 2020 Aug 29;112:102486. Epub 2020 May 29.

Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, via Forlanini 6, 27100, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2020.102486DOI Listing
August 2020

Endothelial TRPV1 as an Emerging Molecular Target to Promote Therapeutic Angiogenesis.

Cells 2020 05 27;9(6). Epub 2020 May 27.

Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/cells9061341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349285PMC
May 2020

Plasma sIL-2Rα levels are associated with disease progression in myelofibrosis with JAK2 but not CALR mutation.

Leuk Res 2020 03 11;90:106319. Epub 2020 Feb 11.

Laboratory of Biochemistry-Biotechnology and Advanced Diagnosis, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico S. Matteo, Pavia, Italy.

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http://dx.doi.org/10.1016/j.leukres.2020.106319DOI Listing
March 2020

Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia.

Exp Hematol 2019 11 1;79:16-25.e3. Epub 2019 Nov 1.

Division of Hematology and Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Biomedical and Neuromotorial Sciences, Alma Mater University, Bologna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2019.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910948PMC
November 2019

Generation of donor-derived Wilms tumor antigen 1-specific cytotoxic T lymphocytes with potent anti-leukemia activity for somatic cell therapy in children given haploidentical stem cell transplantation: a feasibility pre-clinical study.

Cytotherapy 2019 09 4;21(9):958-972. Epub 2019 Jul 4.

Laboratory of Immunology and Transplantation, Fondazione Istituto Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy; Cell Factory, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Clinic-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2019.06.007DOI Listing
September 2019

The role of endothelial colony forming cells in kidney cancer's pathogenesis, and in resistance to anti-VEGFR agents and mTOR inhibitors: A speculative review.

Crit Rev Oncol Hematol 2018 Dec 18;132:89-99. Epub 2018 Sep 18.

Medical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (I.R.C.C.S.) Policlinico San Matteo Foundation, Piazzale Golgi 19, 27100, Pavia, Italy; present address: Department of Internal Medicine, University of Pavia, and Division of Translational Oncology, IRCCS Istituti Clinici Scientifici Maugeri, via S. Maugeri 10, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2018.09.005DOI Listing
December 2018

Manipulating Intracellular Ca2+ Signals to Stimulate Therapeutic Angiogenesis in Cardiovascular Disorders.

Curr Pharm Biotechnol 2018 ;19(9):686-699

Center for the Study of Myelofibrosis, Laboratory of Biochemistry, Biotechnology and Advanced Diagnosis, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

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http://dx.doi.org/10.2174/1389201019666180808165309DOI Listing
February 2019

MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis.

J Clin Oncol 2018 02 9;36(4):310-318. Epub 2017 Dec 9.

Paola Guglielmelli, Giada Rotunno, Carmela Mannarelli, Annalisa Pacilli, Francesco Mannelli, and Alessandro M. Vannucchi, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence; Elisa Rumi, Vittorio Rosti, Giovanni Barosi, and Mario Cazzola, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo; Elisa Rumi and Mario Cazzola, University of Pavia, Pavia; Alessandro Rambaldi, University of Milan, Milan; Alessandro Rambaldi and Tiziano Barbui, Azienda Socio sanitaria Territoriale Papa Giovanni XXIII, Bergamo; Francesco Passamonti, University of Insubria, Varese, Italy; and Terra L. Lasho, Mythri Mudireddy, Maura Nicolosi, Animesh Pardanani, Curtis A. Hanson, Rhett P. Ketterling, Naseema Gangat, and Ayalew Tefferi, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2017.76.4886DOI Listing
February 2018

Acetylcholine induces intracellular Ca oscillations and nitric oxide release in mouse brain endothelial cells.

Cell Calcium 2017 09 12;66:33-47. Epub 2017 Jun 12.

Laboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2017.06.003DOI Listing
September 2017

Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.

Am J Pathol 2017 Aug;187(8):1879-1892

Vascular Biology Laboratory, The FIRC Institute of Molecular Oncology (IFOM) Foundation, Milan, Italy; Department of Immunology, Genetics and Pathology, University of Uppsala, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.04.006DOI Listing
August 2017

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis.

Blood 2017 08 7;130(6):829-831. Epub 2017 Jun 7.

Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA; and.

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http://dx.doi.org/10.1182/blood-2017-04-777417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553577PMC
August 2017

Liposomes as a Putative Tool to Investigate NAADP Signaling in Vasculogenesis.

J Cell Biochem 2017 11 16;118(11):3722-3729. Epub 2017 May 16.

Department of Medicine and Health Sciences "Vincenzo Tiberio", Centre of Nanomedicine, University of Molise, Campobasso 86100, Italy.

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http://dx.doi.org/10.1002/jcb.26019DOI Listing
November 2017

Vascular endothelial growth factor overexpression in myelodysplastic syndrome bone marrow cells: biological and clinical implications.

Leuk Lymphoma 2017 07 29;58(7):1711-1720. Epub 2016 Nov 29.

b Department of Hematology Oncology , IRCCS Policlinico San Matteo Foundation, University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/10428194.2016.1262030DOI Listing
July 2017

Arachidonic acid-evoked Ca signals promote nitric oxide release and proliferation in human endothelial colony forming cells.

Vascul Pharmacol 2016 12 12;87:159-171. Epub 2016 Sep 12.

Department of Cell Biology, Institute of Ophthalmology, University College London, 11-43 Bath Street, EC1V 9EL London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.vph.2016.09.005DOI Listing
December 2016

Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy.

Curr Med Chem 2016 ;23(30):3450-3480

Laboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via Forlanini 6, 27100, Pavia, Italy.

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http://dx.doi.org/10.2174/0929867323666160607111220DOI Listing
February 2017

Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients.

Am J Hematol 2016 09 4;91(9):918-22. Epub 2016 Jul 4.

Department of Experimental and Clinical Medicine and DENOTHE Excellence Center, CRIMM-Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/ajh.24442DOI Listing
September 2016

Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.

J Cell Biochem 2016 10 14;117(10):2260-71. Epub 2016 Mar 14.

Laboratory of General Physiology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, 27100, Italy.

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http://dx.doi.org/10.1002/jcb.25524DOI Listing
October 2016

Expression and function of toll-like receptors in human circulating endothelial colony forming cells.

Immunol Lett 2015 Nov 8;168(1):98-104. Epub 2015 Oct 8.

Laboratory of Neonatal Immunology, Fondazione IRCCS Policlinico "San Matteo", Pavia, Italy; Neonatal Intensive Care Unit, Fondazione IRCCS Policlinico "San Matteo", Pavia, Italy.

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http://dx.doi.org/10.1016/j.imlet.2015.09.014DOI Listing
November 2015

Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells.

Exp Hematol 2015 Dec 19;43(12):1019-1030.e3. Epub 2015 Oct 19.

Laboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.09.002DOI Listing
December 2015

Endothelial progenitor cells support tumour growth and metastatisation: implications for the resistance to anti-angiogenic therapy.

Tumour Biol 2015 Sep 2;36(9):6603-14. Epub 2015 Aug 2.

Unit of Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.

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http://link.springer.com/10.1007/s13277-015-3823-2
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http://dx.doi.org/10.1007/s13277-015-3823-2DOI Listing
September 2015

Critical appraisal of the role of ruxolitinib in myeloproliferative neoplasm-associated myelofibrosis.

Onco Targets Ther 2015 18;8:1091-102. Epub 2015 May 18.

Haematology Research Centre, Division of Experimental Medicine, Department of Medicine, Imperial College London, London, UK.

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http://www.dovepress.com/critical-appraisal-of-the-role-of-r
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http://dx.doi.org/10.2147/OTT.S31916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445786PMC
June 2015

Altered fibronectin expression and deposition by myeloproliferative neoplasm-derived mesenchymal stromal cells.

Br J Haematol 2016 Jan 5;172(1):140-4. Epub 2015 May 5.

Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1111/bjh.13471DOI Listing
January 2016

Conditioned medium from human amniotic mesenchymal stromal cells limits infarct size and enhances angiogenesis.

Stem Cells Transl Med 2015 May 30;4(5):448-58. Epub 2015 Mar 30.

Department of Cardiothoracic and Vascular Sciences, Coronary Care Unit and Laboratory of Clinical and Experimental Cardiology, Laboratory of Experimental Cardiology for Cell and Molecular Therapy, Division of Clinical Immunology, Immunohematology, and Transfusion Service, Center for the Study and Cure of Myelofibrosis, Biotechnology Research Laboratories, and Division of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, Unit of Cardiology, University of Pavia, Pavia, Italy; Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy; Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands; Department of Medicine, University of Cape Town, Cape Town, South Africa

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http://dx.doi.org/10.5966/sctm.2014-0253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414224PMC
May 2015

JAK2 exon 14 skipping in patients with primary myelofibrosis: a minor splice variant modulated by the JAK2-V617F allele burden.

PLoS One 2015 24;10(1):e0116636. Epub 2015 Jan 24.

Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS "Policlinico San Matteo", Pavia (PV), Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116636PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305294PMC
February 2016

Increase of circulating endothelial cells in patients with Hereditary Hemorrhagic Telangiectasia.

Int J Hematol 2015 Jan 3;101(1):23-31. Epub 2014 Dec 3.

Laboratori Sperimentali di Ricerca Area Biotecnologie, IRCCS Fondazione "Policlinico S. Matteo", Viale Golgi 19, 27100, Pavia, Italy.

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http://dx.doi.org/10.1007/s12185-014-1698-4DOI Listing
January 2015

Store-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma.

Biomed Res Int 2014 9;2014:739494. Epub 2014 Jul 9.

Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, Via Forlanini 6, 27100 Pavia, Italy ; Department of Physiology, University of Pavia, Via Forlanini 6, 27100 Pavia, Italy.

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http://dx.doi.org/10.1155/2014/739494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119920PMC
May 2015

Hydrogen sulphide triggers VEGF-induced intracellular Ca²⁺ signals in human endothelial cells but not in their immature progenitors.

Cell Calcium 2014 Sep 27;56(3):225-34. Epub 2014 Jul 27.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via Forlanini 6, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2014.07.010DOI Listing
September 2014

CD14(bright)CD16(low) intermediate monocytes expressing Tie2 are increased in the peripheral blood of patients with primary myelofibrosis.

Exp Hematol 2014 Apr 11;42(4):244-6. Epub 2013 Dec 11.

Biotechnology Research Area, IRCCS Policlinico San Matteo Foundation, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2013.12.002DOI Listing
April 2014

Remote ischemic post-conditioning of the lower limb during primary percutaneous coronary intervention safely reduces enzymatic infarct size in anterior myocardial infarction: a randomized controlled trial.

JACC Cardiovasc Interv 2013 Oct;6(10):1055-63

Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy; SC Cardiologia, Azienda Sanitaria Locale 3 Ospedale Villa Scassi, Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2013.05.011DOI Listing
October 2013

Orai1 and transient receptor potential channels as novel molecular targets to impair tumor neovascularization in renal cell carcinoma and other malignancies.

Anticancer Agents Med Chem 2014 Feb;14(2):296-312

Laboratory of Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via Forlanini 6, 27100, Pavia, Italy.

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http://dx.doi.org/10.2174/18715206113139990315DOI Listing
February 2014

Effects of mitochondrial ferritin overexpression in normal and sideroblastic erythroid progenitors.

Br J Haematol 2013 Jun 10;161(5):726-37. Epub 2013 Apr 10.

Department of Internal Medicine, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1111/bjh.12316DOI Listing
June 2013

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis.

Haematologica 2013 Apr 12;98(4):514-7. Epub 2013 Feb 12.

Biotechnology Laboratories, Department of Molecular Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

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http://dx.doi.org/10.3324/haematol.2012.076752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659980PMC
April 2013

Management of myeloproliferative neoplasms: from academic guidelines to clinical practice.

Curr Hematol Malig Rep 2012 Mar;7(1):50-6

Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, IRCCS Policlinico S. Matteo Foundation, Viale Golgi 19, Pavia, Italy.

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http://dx.doi.org/10.1007/s11899-011-0109-7DOI Listing
March 2012

Cell fusion in tumor progression: the isolation of cell fusion products by physical methods.

Cancer Cell Int 2011 Sep 20;11:32. Epub 2011 Sep 20.

Department of Internal Medicine IRCCS Policlinico San Matteo, viale Golgi 19, Pavia 27100 Italy and University of Pavia, Strada Nuova, Pavia 27100; Italy.

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http://dx.doi.org/10.1186/1475-2867-11-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187729PMC
September 2011

Therapeutic approaches in myelofibrosis.

Expert Opin Pharmacother 2011 Jul 4;12(10):1597-611. Epub 2011 Apr 4.

IRCCS Policlinico S. Matteo Foundation, Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, Viale Golgi 19, 27100 Pavia, Italy.

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http://dx.doi.org/10.1517/14656566.2011.568939DOI Listing
July 2011

Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis.

Cytokine 2011 Jan 30;53(1):100-6. Epub 2010 Aug 30.

Laboratory of Clinical Epidemiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.cyto.2010.07.427DOI Listing
January 2011

From cancer patients to cancer survivors: the issue of Cardioncology--a biological perspective.

Eur J Cancer 2010 Mar 28;46(4):697-702. Epub 2009 Dec 28.

Fondazione IRCCS Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.1016/j.ejca.2009.12.011DOI Listing
March 2010

The early- and intermediate-term toxicity to primitive hematopoietic progenitor cells of three chemotherapy regimens for advanced hodgkin lymphoma.

Clin Lymphoma Myeloma 2009 Dec;9(6):425-9

Medicina Interna e Gastroenterologia, Università di Pavia, Fondazione IRCCS Policlinico S. Matteo, P.le Golgi no 2, 27100 Pavia, Italy.

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http://dx.doi.org/10.3816/CLM.2009.n.084DOI Listing
December 2009

Novel strategies for patients with chronic myeloproliferative disorders.

Curr Opin Hematol 2009 Mar;16(2):129-34

Unit of Clinical Epidemiology and Center for the Study of Myelofibrosis, Pavia, Italy.

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http://dx.doi.org/10.1097/MOH.0b013e3283257a9eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368353PMC
March 2009