Publications by authors named "Vittoria Pagliarini"

20Publications

Androgen Receptor signaling promotes the neural progenitor cell pool in the developing cortex.

J Neurochem 2020 Sep 21. Epub 2020 Sep 21.

Laboratory of Neuroembryology, IRCCS Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1111/jnc.15192DOI Listing
September 2020

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.

Cell Rep 2020 Jun;31(9):107703

Fondazione Santa Lucia, IRCCS, Rome, Italy; Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107703DOI Listing
June 2020

Splicing Dysregulation as Oncogenic Driver and Passenger Factor in Brain Tumors.

Cells 2019 12 18;9(1). Epub 2019 Dec 18.

Laboratory of Neuroembryology, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy.

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http://dx.doi.org/10.3390/cells9010010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016899PMC
December 2019

Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells.

J Neurochem 2020 04 8;153(2):264-275. Epub 2020 Jan 8.

Department of Neuroscience, Section of Human Anatomy, Catholic University of the Sacred Heart, Rome, Italy.

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http://dx.doi.org/10.1111/jnc.14935DOI Listing
April 2020

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization.

Nucleic Acids Res 2020 01;48(2):633-645

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome 00168, Italy.

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http://dx.doi.org/10.1093/nar/gkz1117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954450PMC
January 2020

Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders.

Hum Genet 2017 09 22;136(9):1215-1235. Epub 2017 Apr 22.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s00439-017-1802-yDOI Listing
September 2017

Essential role of ICAM-1 in aldosterone-induced atherosclerosis.

Int J Cardiol 2017 Apr 5;232:233-242. Epub 2017 Jan 5.

Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, 00166 Rome, Italy; Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890338PMC
April 2017

SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy.

J Cell Biol 2015 Oct 5;211(1):77-90. Epub 2015 Oct 5.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy Laboratory of Neuroembryology, Fondazione Santa Lucia, 00143 Rome, Italy

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http://jcb.rupress.org/content/211/1/77.full.pdf
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http://www.jcb.org/lookup/doi/10.1083/jcb.201502059
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http://dx.doi.org/10.1083/jcb.201502059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602033PMC
October 2015

Splicing Regulation: A Molecular Device to Enhance Cancer Cell Adaptation.

Biomed Res Int 2015 26;2015:543067. Epub 2015 Jul 26.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy ; Laboratory of Neuroembryology, Fondazione Santa Lucia, 00143 Rome, Italy.

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http://dx.doi.org/10.1155/2015/543067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529921PMC
May 2016

The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability.

Front Genet 2015 15;6:142. Epub 2015 Apr 15.

Department of Biomedicine and Prevention, University of Rome Tor Vergata , Rome, Italy ; Laboratory of Neuroembryology, Fondazione Santa Lucia , Rome, Italy.

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http://dx.doi.org/10.3389/fgene.2015.00142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397863PMC
April 2015

Downregulation of E2F1 during ER stress is required to induce apoptosis.

J Cell Sci 2015 Mar 22;128(6):1166-79. Epub 2015 Jan 22.

National Institute for Infectious Disease 'L. Spallanzani' IRCCS, 00149 Rome, Italy Cellular and Developmental Lab, Department of Biology, University of Rome 'Tor Vergata', 00133 Rome, Italy

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http://dx.doi.org/10.1242/jcs.164103DOI Listing
March 2015

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

Clin Cancer Res 2011 Apr 26;17(8):2216-26. Epub 2011 Jan 26.

Dermatological Sciences, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle Upon Tyne, UK.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-3003DOI Listing
April 2011