Publications by authors named "Vito Ruggiero"

14Publications

Targeting the Toll-like receptor/interleukin 1 receptor pathway in human diseases: rational design of MyD88 inhibitors.

Clin Lymphoma Myeloma Leuk 2013 Apr 13;13(2):222-6. Epub 2013 Mar 13.

Department of Biomedicine, Prevention, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.clml.2013.02.003DOI Listing
April 2013

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

Rheumatology (Oxford) 2010 Dec 25;49(12):2281-9. Epub 2010 Aug 25.

Cytometry and B-cell Development Unit, Research Center, Department of Nephrology and Urology, Children Hospital Bambino Gesù, and Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1093/rheumatology/keq226DOI Listing
December 2010

Targeting TLR/IL-1R signalling in human diseases.

Mediators Inflamm 2010 8;2010:674363. Epub 2010 Apr 8.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://www.hindawi.com/journals/mi/2010/674363/
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http://dx.doi.org/10.1155/2010/674363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852602PMC
July 2010

Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases.

J Biol Chem 2009 Oct 13;284(41):28093-103. Epub 2009 Aug 13.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.M109.004465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788860PMC
October 2009

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.

J Leukoc Biol 2007 Oct 4;82(4):801-10. Epub 2007 Jun 4.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata," Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1189/jlb.1206746DOI Listing
October 2007

Effect of a novel immunosuppressant, ST1959, on the immune system and renal allograft survival in rats.

Transplantation 2005 Jul;80(2):231-6

Transplant Research Center Chiara Cucchi de Alessandri e Gilberto Crespi, Mario Negri Institute for Pharmacological Research, Villa Camozzi, Ranica, Bergamo, Italy.

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http://dx.doi.org/10.1097/01.tp.0000165434.89700.a7DOI Listing
July 2005

Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B.

J Biol Chem 2005 Apr 8;280(16):15809-14. Epub 2005 Mar 8.

Department of Public Health and Cell Biology, University of Rome "Tor Vergata," 00173 Rome, Italy.

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http://dx.doi.org/10.1074/jbc.C400613200DOI Listing
April 2005