Virginia M Klimek

Virginia M Klimek

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Virginia M Klimek

Virginia M Klimek

Publications by authors named "Virginia M Klimek"

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30Publications

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Molecular and cytogenetic characteristics of myeloid malignancies following luminal gastrointestinal cancer.

Leuk Res 2019 Jul 24;82:19-23. Epub 2019 May 24.

Department of Medicine, Memorial Sloan Kettering Cancer Center, USA; Division of Hematologic Malignancies, Leukemia Service, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA; Department of Medicine, Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.05.010DOI Listing
July 2019

Micafungin versus posaconazole prophylaxis in acute leukemia or myelodysplastic syndrome: A randomized study.

J Infect 2018 09 7;77(3):227-234. Epub 2018 May 7.

Infectious Disease Service, Division of Subspecialty Medicine, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2018.03.015DOI Listing
September 2018

The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.

Nat Med 2017 Nov 18;23(11):1369-1376. Epub 2017 Sep 18.

Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nm.4416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677536PMC
November 2017

Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.

Cell Stem Cell 2017 03 16;20(3):315-328.e7. Epub 2017 Feb 16.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337161PMC
March 2017

Therapy-related myeloid neoplasms: what's in a name?

Curr Opin Hematol 2016 Mar;23(2):161-6

aDepartment of Medicine, Leukemia Service bHospital Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000222DOI Listing
March 2016

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.

Nat Commun 2016 Feb 22;7:10739. Epub 2016 Feb 22.

Molecular Pharmacology and Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms10739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764878PMC
February 2016

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.

Nat Biotechnol 2015 Jun 23;33(6):646-55. Epub 2015 Mar 23.

1] Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [2] The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [3] The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [4] Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington, USA. [5] Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, USA. [6] Department of Pathology, University of Washington, Seattle, Washington, USA. [7] Division of Hematology and Medical Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.3178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464949PMC
June 2015

Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study.

Cancer Immunol Immunother 2015 Feb 29;64(2):237-47. Epub 2014 Oct 29.

Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, 1429 First Avenue, New York, NY, 10021, USA.

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http://dx.doi.org/10.1007/s00262-014-1628-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317517PMC
February 2015

Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies.

Cancer Discov 2014 May 3;4(5):538-45. Epub 2014 Mar 3.

1Human Oncology and Pathogenesis Program, 2Leukemia Service, 3Gastrointestinal Oncology Service, 4Melanoma and Immunotherapeutics Service, Department of Medicine, 5Molecular Diagnostics Service, Department of Pathology, 6Department of Radiology, 7Center for Molecular Oncology, 8Ludwig Center for Cancer Immunotherapy, and 9Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center; and 10Weill Cornell Medical College, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-13-1038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850735PMC
May 2014

Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia.

Haematologica 2013 Jun 24;98(6):908-12. Epub 2013 Jan 24.

Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.3324/haematol.2012.076729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669447PMC
June 2013

Recent advances in the management of therapy-related myelodysplastic syndromes and acute myeloid leukemia.

Curr Opin Hematol 2013 Mar;20(2):137-43

Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1097/MOH.0b013e32835d82e6DOI Listing
March 2013

Translocation t(11;17) in de novo myelodysplastic syndrome not associated with acute myeloid or acute promyelocytic leukemia.

Acta Haematol 2013 7;129(1):48-54. Epub 2012 Nov 7.

Department of Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1159/000342493DOI Listing
February 2013

Progression of RAS-mutant leukemia during RAF inhibitor treatment.

N Engl J Med 2012 Dec 7;367(24):2316-21. Epub 2012 Nov 7.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1056/NEJMoa1208958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627494PMC
December 2012

Efficacy of hypomethylating agents in therapy-related myelodysplastic syndromes.

Leuk Res 2012 Sep 17;36(9):1093-7. Epub 2012 May 17.

Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.leukres.2012.04.025DOI Listing
September 2012

Phase I trial of sodium salicylate in patients with myelodysplastic syndromes and acute myelogenous leukemia.

Leuk Res 2012 May 9;36(5):570-4. Epub 2011 Dec 9.

Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.leukres.2011.10.023DOI Listing
May 2012

It dices, it splices!

Blood 2011 Dec;118(24):6237-8

Memorial Sloan-Kettering Cancer Center, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-10-38
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http://dx.doi.org/10.1182/blood-2011-10-386540DOI Listing
December 2011

Hypomethylating agents in acute lymphoblastic leukemia: untapped potential?

Leuk Lymphoma 2011 Jan 7;52(1):7-8. Epub 2010 Oct 7.

Department of Medicine, Memorial Sloan-Kettering Cancer Center, NewYork, NY, USA.

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http://dx.doi.org/10.3109/10428194.2010.524330DOI Listing
January 2011

Serum levels of melanoma-inhibiting activity do not predict relapse in melanoma patients.

Cytokines Cell Mol Ther 2002 Dec;7(2):71-4

Memorial Sloan-Kettering Cancer Center, Department of Medicine, Clinical Immunology Service, New York, NY, USA.

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http://dx.doi.org/10.1080/13684730412331302072DOI Listing
December 2002