Vincent T H B M Smit

Vincent T H B M Smit

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Vincent T H B M Smit

Vincent T H B M Smit

Publications by authors named "Vincent T H B M Smit"

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Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer.

Int J Gynecol Pathol 2019 Aug 26. Epub 2019 Aug 26.

Departments of Obstetrics and Gynecology (K.E.K., M.I.E.V.P.) Pathology (V.T.H.B.M.S., T.B.), Leiden University Medical Centre, Leiden, The Netherlands Department of Pathology, Ghent University Hospital, Gent (K.K.V.D.V.) Department of Pathology, University Hospitals Leuven, Leuven (A.S.V.R.), Belgium Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada (C.B.G.) Department of Cellular Pathology, Princess Alexandra Hospital, Harlow, Essex (S.A.) Department of Cellular Pathology, St. James's University Hospital, Leeds (D.A.) Department of Cellular Pathology, Barts Health NHS Trust, London (A.F., N.S.) Department of Cellular Pathology, University Hospitals Birmingham NHS Trust, Birmingham (R.G., B.T., J.V.) Department of Pathology, Airedale General Hospital, Keighley (N.R.G.) Department of Cellular Pathology, Stepping Hill Hospital, Stockport (R.H.) Department of Histopathology, Manor Hospital, Walsall Healthcare NHS Trust, Walsall (Y.L.H.) Department of Pathology, Belfast Health and Social Care Trust, Belfast (W.G.M.) Department of Cellular Pathology, Royal United Hospital, Bath (P.M.) Department of Pathology, Cambridge University Hospitals NHS Trust, Cambridge (B.R.) Department of Pathology, Royal Derby Hospital, Derby (G.V.S) Department of Histopathology, The Royal Sussex County Hospital, Brighton (M.V.), UK Division of Gynecologic, Breast & Perinatal Pathology, University Hospital Leipzig, Leipzig, Germany (L.C.H.) Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (K.J.P.).

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http://dx.doi.org/10.1097/PGP.0000000000000631DOI Listing
August 2019

Blinded histopathological characterisation of POLE exonuclease domain-mutant endometrial cancers: sheep in wolf's clothing.

Histopathology 2018 Jan 10;72(2):248-258. Epub 2017 Oct 10.

Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/his.13338DOI Listing
January 2018

The prognostic value of the tumour-stroma ratio in primary operable invasive cancer of the breast: a validation study.

Breast Cancer Res Treat 2017 Nov 9;166(2):435-445. Epub 2017 Aug 9.

Department of Surgery, Leiden University Medical Centre, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10549-017-4445-8DOI Listing
November 2017

Accuracy of the online prognostication tools PREDICT and Adjuvant! for early-stage breast cancer patients younger than 50 years.

Eur J Cancer 2017 06 14;78:37-44. Epub 2017 Apr 14.

Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; Division of Molecular Pathology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2017.03.015DOI Listing
June 2017

Stathmin is a highly sensitive and specific biomarker for vulvar high-grade squamous intraepithelial lesions.

J Clin Pathol 2016 Dec 25;69(12):1070-1075. Epub 2016 May 25.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1136/jclinpath-2016-203676DOI Listing
December 2016

Identification of cell-surface markers for detecting breast cancer cells in ovarian tissue.

Arch Gynecol Obstet 2016 08 5;294(2):385-93. Epub 2016 Mar 5.

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00404-016-4036-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937067PMC
August 2016

Exploring Morphologic and Molecular Aspects of Endometrial Cancer Under Progesterone Treatment in the Context of Fertility Preservation.

Int J Gynecol Cancer 2016 Mar;26(3):483-90

Departments of *Gynaecology and †Pathology, Leiden University Medical Center, Leiden; and Departments of ‡Gynaecology and §Pathology, Medical Center Haaglanden, The Hague, The Netherlands.

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http://dx.doi.org/10.1097/IGC.0000000000000629DOI Listing
March 2016

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

J Clin Oncol 2016 Feb 23;34(5):409-18. Epub 2015 Dec 23.

Alexandra J. van den Broek, Laura J. van 't Veer, Sten Cornelissen, Annegien Broeks, Emiel J. Rutgers, Flora E. van Leeuwen, and Marjanka K. Schmidt, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam; Maartje J. Hooning and Caroline Seynaeve, Erasmus MC Cancer Institute, Rotterdam; Vincent T.H.B.M. Smit, Cees J. Cornelisse, and Rob A.E.M. Tollenaar, Leiden University Medical Center, Leiden; Mike van Beek, PAMM, Catharina Hospital, Eindhoven; Maryska L. Janssen-Heijnen, Netherlands Comprehensive Cancer Organization, Eindhoven, and VieCuri Medical Centre, Venlo; Pieter J. Westenend, Laboratory for Pathology, Dordrecht; Jan J. Jobsen, Medisch Spectrum Twente, Enschede; and Sabine Sieling, Netherlands Comprehensive Cancer Organization, Utrecht, Netherlands.

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http://jco.ascopubs.org/content/early/2015/12/22/JCO.2015.62
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.62.3942
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http://dx.doi.org/10.1200/JCO.2015.62.3942DOI Listing
February 2016

Total number of lymph nodes in oncologic resections, is there more to be found?

J Gastrointest Surg 2015 May 18;19(5):943-8. Epub 2015 Feb 18.

Department of Surgery, K6-50, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands,

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http://dx.doi.org/10.1007/s11605-015-2764-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412279PMC
May 2015

Nomograms for prediction of outcome with or without adjuvant radiation therapy for patients with endometrial cancer: a pooled analysis of PORTEC-1 and PORTEC-2 trials.

Int J Radiat Oncol Biol Phys 2015 Mar 30;91(3):530-9. Epub 2015 Jan 30.

Department of Radiation Oncology, MAASTRO, GROW, University Medical Centre Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.ijrobp.2014.11.022DOI Listing
March 2015

Searching for metastases in ovarian tissue before autotransplantation: a tailor-made approach.

Fertil Steril 2015 Feb 10;103(2):469-77. Epub 2014 Dec 10.

Department of Gynecology, Leiden University Medical Center, Leiden, the Netherlands; Department of Gynecology, Reinier de Graaf Gasthuis Delft, Delft, the Netherlands.

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http://dx.doi.org/10.1016/j.fertnstert.2014.11.001DOI Listing
February 2015

Vaccine-induced tumor necrosis factor-producing T cells synergize with cisplatin to promote tumor cell death.

Clin Cancer Res 2015 Feb 12;21(4):781-94. Epub 2014 Dec 12.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center (LUMC), Leiden, the Netherlands. ISA Pharmaceuticals, Leiden, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2142DOI Listing
February 2015

Prognostic significance of POLE proofreading mutations in endometrial cancer.

J Natl Cancer Inst 2015 Jan 12;107(1):402. Epub 2014 Dec 12.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (DNC, IPMT); Oxford Cancer Centre, Churchill Hospital, Oxford, UK (DNC); Department of Pathology (ES, NtH, VTHBMS, TB) and Department of Clinical Oncology (RAN, CLC), Leiden University Medical Center, Leiden, the Netherlands; Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland (NV, AN, PJW); Vesalius Research Center (VRC), VIB, Leuven, Belgium (JD, DL); Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Belgium (FA, DL); Department of Obstetrics & Gynecology, Division of Gynecologic Oncology, University Hospitals Gasthuisberg, Leuven, Belgium (FA); Genomic Medicine Theme, Oxford Comprehensive Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (IPMT); Department of Radiation Oncology, University Medical Centrum Utrecht, the Netherlands (IMJS); Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, the Netherlands (JJJ).

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http://dx.doi.org/10.1093/jnci/dju402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301706PMC
January 2015

High concordance of molecular tumor alterations between pre-operative curettage and hysterectomy specimens in patients with endometrial carcinoma.

Gynecol Oncol 2014 May 18;133(2):197-204. Epub 2014 Feb 18.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.02.012DOI Listing
May 2014

The prognostic value of apoptotic and proliferative markers in breast cancer.

Breast Cancer Res Treat 2013 Nov 6;142(2):323-39. Epub 2013 Nov 6.

Department of Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2748-yDOI Listing
November 2013

Tumor immune subtypes distinguish tumor subclasses with clinical implications in breast cancer patients.

Breast Cancer Res Treat 2013 Nov 7;142(2):355-64. Epub 2013 Nov 7.

Departments of Surgery, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10549-013-2752-2DOI Listing
November 2013

The CpG island methylator phenotype: what's in a name?

Cancer Res 2013 Oct 25;73(19):5858-68. Epub 2013 Jun 25.

Authors' Affiliations: Departments of Epidemiology and Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht; Department of Surgery, Orbis Medical Center, Sittard-Geleen; Department of Pathology, Leiden University Medical Center, Leiden; Department of Neurology, Erasmus University Medical Center, Erasmus University, Rotterdam, the Netherlands; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium; and The Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4306DOI Listing
October 2013

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

Authors:
Annegien Broeks Marjanka K Schmidt Mark E Sherman Fergus J Couch John L Hopper Gillian S Dite Carmel Apicella Letitia D Smith Fleur Hammet Melissa C Southey Laura J Van 't Veer Renate de Groot Vincent T H B M Smit Peter A Fasching Matthias W Beckmann Sebastian Jud Arif B Ekici Arndt Hartmann Alexander Hein Ruediger Schulz-Wendtland Barbara Burwinkel Frederik Marme Andreas Schneeweiss Hans-Peter Sinn Christof Sohn Sandrine Tchatchou Stig E Bojesen Børge G Nordestgaard Henrik Flyger David D Ørsted Diljit Kaur-Knudsen Roger L Milne Jose I Arias Pérez Pilar Zamora Primitiva Menéndez Rodríguez Javier Benítez Hiltrud Brauch Christina Justenhoven Yon-Dschun Ko Ute Hamann Hans-Peter Fischer Thomas Brüning Beate Pesch Jenny Chang-Claude Shan Wang-Gohrke Michael Bremer Johann H Karstens Peter Hillemanns Thilo Dörk Heli A Nevanlinna Tuomas Heikkinen Päivi Heikkilä Carl Blomqvist Kristiina Aittomäki Kirsimari Aaltonen Annika Lindblom Sara Margolin Arto Mannermaa Veli-Matti Kosma Jaana M Kauppinen Vesa Kataja Päivi Auvinen Matti Eskelinen Ylermi Soini Georgia Chenevix-Trench Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Helene Holland Diether Lambrechts Bart Claes Thijs Vandorpe Patrick Neven Hans Wildiers Dieter Flesch-Janys Rebecca Hein Thomas Löning Matthew Kosel Zachary S Fredericksen Xianshu Wang Graham G Giles Laura Baglietto Gianluca Severi Catriona McLean Christopher A Haiman Brian E Henderson Loic Le Marchand Laurence N Kolonel Grethe Grenaker Alnæs Vessela Kristensen Anne-Lise Børresen-Dale David J Hunter Susan E Hankinson Irene L Andrulis Anna Marie Mulligan Frances P O'Malley Peter Devilee Petra E A Huijts Rob A E M Tollenaar Christi J Van Asperen Caroline S Seynaeve Stephen J Chanock Jolanta Lissowska Louise Brinton Beata Peplonska Jonine Figueroa Xiaohong R Yang Maartje J Hooning Antoinette Hollestelle Rogier A Oldenburg Agnes Jager Mieke Kriege Bahar Ozturk Geert J L H van Leenders Per Hall Kamila Czene Keith Humphreys Jianjun Liu Angela Cox Daniel Connley Helen E Cramp Simon S Cross Sabapathy P Balasubramanian Malcolm W R Reed Alison M Dunning Douglas F Easton Manjeet K Humphreys Carlos Caldas Fiona Blows Kristy Driver Elena Provenzano Jan Lubinski Anna Jakubowska Tomasz Huzarski Tomasz Byrski Cezary Cybulski Bohdan Gorski Jacek Gronwald Paul Brennan Suleeporn Sangrajrang Valerie Gaborieau Chen-Yang Shen Chia-Ni Hsiung Jyh-Cherng Yu Shou-Tung Chen Giu-Cheng Hsu Ming-Feng Hou Chiun-Sheng Huang Hoda Anton-Culver Argyrios Ziogas Paul D P Pharoah Montserrat Garcia-Closas

Hum Mol Genet 2011 Aug 19;20(16):3289-303. Epub 2011 May 19.

Department of Experimental Therapy, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://hmg.oxfordjournals.org/content/20/16/3289.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddr228
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http://dx.doi.org/10.1093/hmg/ddr228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140824PMC
August 2011

Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients.

Breast Cancer Res Treat 2011 Feb 2;125(3):687-96. Epub 2010 Apr 2.

Departments of Surgery, Leiden University Medical Center, P.O Box 9600, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10549-010-0855-6DOI Listing
February 2011

Reproducibility and validation of tumour stroma ratio scoring on oesophageal adenocarcinoma biopsies.

Eur J Cancer 2011 Feb 29;47(3):375-82. Epub 2010 Oct 29.

Department of Surgical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2010.09.043DOI Listing
February 2011

Methylation profiles of endometrioid and serous endometrial cancers.

Endocr Relat Cancer 2010 Sep 25;17(3):663-73. Epub 2010 Jun 25.

Department of Gynaecological Oncology, University Medical Centre Utrecht, 3508 GA Utrecht, The Netherlands.

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https://erc.bioscientifica.com/view/journals/erc/17/3/663.xm
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http://dx.doi.org/10.1677/ERC-10-0014DOI Listing
September 2010

The stromal part of adenocarcinomas of the oesophagus: does it conceal targets for therapy?

Eur J Cancer 2010 Mar 13;46(4):720-8. Epub 2010 Jan 13.

Department of Surgical Oncology, the Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2009.12.006DOI Listing
March 2010

Clinical challenges and images in GI. Syphilitic sigmoiditis complicated by membranous nephropathy.

Gastroenterology 2008 Aug 9;135(2):363, 716. Epub 2008 Jul 9.

Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2008.06.055DOI Listing
August 2008

Double bioprosthetic valve replacement in right-sided carcinoid heart disease.

Ann Thorac Surg 2005 Jun;79(6):2147-9

Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.athoracsur.2003.12.102DOI Listing
June 2005

Different mechanisms of chromosome 16 loss of heterozygosity in well- versus poorly differentiated ductal breast cancer.

Genes Chromosomes Cancer 2004 Oct;41(2):109-16

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20070DOI Listing
October 2004

Infiltrating leukocytes confound the detection of E-cadherin promoter methylation in tumors.

Biochem Biophys Res Commun 2004 Jun;319(2):697-704

Department of Pathology, Leiden University Medical Center, P.O. Box 9600, L1-Q, NL-2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.bbrc.2004.05.041DOI Listing
June 2004

Assessment of serum matrix metalloproteinases MMP-2 and MMP-9 after human liver transplantation: increased serum MMP-9 level in acute rejection.

Transplantation 2004 Jun;77(11):1646-52

Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/01.tp.0000131170.67671.75DOI Listing
June 2004

Prognostic significance of periodic acid-Schiff-positive patterns in primary breast cancer and its lymph node metastases.

Breast Cancer Res Treat 2004 Mar;84(2):117-30

Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1023/B:BREA.0000018408.77854.d1DOI Listing
March 2004

Elective surgery for fibroelastoma of the aortic valve.

Ann Thorac Surg 2004 Feb;77(2):725

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S000349750300471
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http://dx.doi.org/10.1016/S0003-4975(03)00471-5DOI Listing
February 2004

Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma.

Cancer 2004 Feb;100(4):764-72

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cncr.20040DOI Listing
February 2004

Long-term outcome in endometrial carcinoma favors a two- instead of a three-tiered grading system.

Int J Radiat Oncol Biol Phys 2002 Mar;52(4):1067-74

Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0360-3016(01)02710-9DOI Listing
March 2002