Publications by authors named "Vincent Procaccio"

100Publications

Mutations in the m-AAA proteases AFG3L2 and SPG7 are causing isolated dominant optic atrophy.

Neurol Genet 2020 Jun 20;6(3):e428. Epub 2020 May 20.

MitoLab Team (M.C., A.C., C.B., D.G., V.D.-D., S.L., V.P., P.R., D.B., P.A.-B., G.L.), UMR CNRS 6015-INSERM U1083, Institut MitoVasc, Angers University and Hospital; Genetics and immuno-cell therapy Team (M.C.), Mohammed First University, Oujda, Morocco; Departments of Biochemistry and Genetics (C.B., D.G., V.D.-D., E.C., V.P., P.R., D.B., P.A.-B.), University Hospital Angers; Department of Ophthalmology (A.M.), Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium; Neuroophthalmology Department (C.V.), Rothschild Ophthalmologic Foundation, Paris; Exploration of Visual Function and Neuro-Ophthalmology Department (V.S., S.D.-D., I.D.B.), Lille University Hospital, Rue Emilie Laine, Lille Cedex; CHU Bordeaux (C.G.), Service de Génétique Médicale, Centre de Référence « Neurogénétique » and Université de Bordeaux, INSERM U 1211, Laboratoire Maladies Rares, Génétique et Métabolisme (MRGM) Bordeaux; School of Optometry and Vision Sciences (M.V.), Cardiff University and Cardiff Eye Unit, University Hospital of Wales; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology (N.J., P.Y.-W.-M.), London; Department of Clinical Neurosciences (P.Y.-W.-M.), Cambridge Centre for Brain Repair and MRC Mitochondrial Biology Unit, University of Cambridge; Cambridge Eye Unit (P.Y.-W.-M.), Addenbrooke's Hospital, Cambridge University Hospitals, UK; IRCCS Istituto Delle Scienze Neurologiche di Bologna (F.T., L.C., C.L.M., V.C.), Bellaria Hospital; Unit of Neurology (C.L.M., V.C.), Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Italy; Centre de Compétence Maladies Rares (X.Z.), Clinique Pluridisciplinaire Jules Verne, Nantes; and National Centre in Rare Diseases (I.M.), Genetics of Sensory Diseases, University Hospital, Montpellier, France.

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http://dx.doi.org/10.1212/NXG.0000000000000428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251510PMC
June 2020

Clinical phenotype of mitochondrial diabetes due to rare mitochondrial DNA mutations.

Ann Endocrinol (Paris) 2020 Jun 28;81(2-3):68-77. Epub 2020 Apr 28.

Service d'endocrinologie, diabétologie et médecine de la reproduction, hôpital de l'Archet 2, université Côte d'Azur, CHU de Nice, Nice, France; Institut national de la santé et de la recherche médicale (Inserm), UMR U1065/UNS, Centre méditerranéen de médecine moléculaire (C3M), équipe 5 « Cellular Basis and Signaling of Tumor Metabolism », Université Côte d'Azur, CHU de Nice, Nice, France. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2020.04.007DOI Listing
June 2020

The cytokine profile of follicular fluid changes during ovarian ageing.

J Gynecol Obstet Hum Reprod 2020 Apr 3;49(4):101704. Epub 2020 Feb 3.

Reproductive Biology Unit, Angers University Hospital, 49000, Angers, France; MITOVASC Institute, CNRS 6015, INSERM U1083, Angers University, 49000, Angers, France.

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http://dx.doi.org/10.1016/j.jogoh.2020.101704DOI Listing
April 2020

Data-Mining Approach on Transcriptomics and Methylomics Placental Analysis Highlights Genes in Fetal Growth Restriction.

Front Genet 2019 9;10:1292. Epub 2020 Jan 9.

Unité Mixte de Recherche (UMR) MITOVASC, Équipe Mitolab, Centre National de la Recherche Scientifique (CNRS) 6015, Institut National de la Santé et de la Recherche Médicale (INSERM) U1083, Université d'Angers, Angers, France.

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http://dx.doi.org/10.3389/fgene.2019.01292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962302PMC
January 2020

First characterization of LHON pedigrees in North Africa.

Eye (Lond) 2020 Nov 2;34(11):2138-2139. Epub 2020 Jan 2.

MitoLab team, Institut MitoVasc, UMR CNRS 6015, INSERM U1083, Université d'Angers, Angers, France.

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http://dx.doi.org/10.1038/s41433-019-0755-xDOI Listing
November 2020

Oxidative stress contributes differentially to the pathophysiology of Charcot-Marie-Tooth disease type 2K.

Exp Neurol 2020 01 23;323:113069. Epub 2019 Oct 23.

MitoLab, UMR CNRS 6015-INSERM 1083, MitoVasc Institute, University of Angers, Angers, France; University Hospital of Angers, Department of Biochemistry and Genetics, F-49100 Angers, France.

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http://dx.doi.org/10.1016/j.expneurol.2019.113069DOI Listing
January 2020

Metabolomics reveals highly regional specificity of cerebral sexual dimorphism in mice.

Prog Neurobiol 2020 01 23;184:101698. Epub 2019 Sep 23.

Département de Biochimie et Génétique, Centre Hospitalier Universitaire d'Angers, France; Equipe Mitolab, Unité Mixte de Recherche MITOVASC, CNRS 6015, INSERM U1083, Université d'Angers, Angers, France. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2019.101698DOI Listing
January 2020

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.

Nat Commun 2019 07 12;10(1):3094. Epub 2019 Jul 12.

Department of Neuromuscular Disorders, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/s41467-019-10910-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626132PMC
July 2019

Warburg-like effect is a hallmark of complex I assembly defects.

Biochim Biophys Acta Mol Basis Dis 2019 09 20;1865(9):2475-2489. Epub 2019 May 20.

UMR CNRS 6015-INSERM U1083, MitoVasc Institute, University of Angers, Angers, France; Department of Biochemistry and Genetics, University Hospital of Angers, F-49000, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439193017
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http://dx.doi.org/10.1016/j.bbadis.2019.05.011DOI Listing
September 2019

High mitochondrial DNA copy number is associated with longer survival in young patients with glioblastoma.

Neuro Oncol 2019 Apr 26. Epub 2019 Apr 26.

Department of Genetic Biochemistry, University Hospital of Angers and MitoLab, MitoVasc Institute, National Institute of Health and Medical Research (INSERM), University of Angers, Angers, France.

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http://dx.doi.org/10.1093/neuonc/noz072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682206PMC
April 2019

Metabolomic Profiling of Aqueous Humor in Glaucoma Points to Taurine and Spermine Deficiency: Findings from the Eye-D Study.

J Proteome Res 2019 03 11;18(3):1307-1315. Epub 2019 Feb 11.

Unité Mixte de Recherche MITOVASC, équipe Mitolab, Centre National de la Recherche Scientifique 6015, Institut National de la Santé et de la Recherche Médicale U1083 , Université d'Angers , Angers 49035 , France.

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http://dx.doi.org/10.1021/acs.jproteome.8b00915DOI Listing
March 2019

[Towards an harmonization of diagnosis by NGS of neuromuscular diseases - Actions of the Molecular Genetics sub-group of FILNEMUS].

Med Sci (Paris) 2018 Nov 12;34 Hors série n°2:20-22. Epub 2018 Nov 12.

CHRU Montpellier, Laboratoire de Génétique moléculaire, Montpellier, France - APHM, Département de Génétique Médicale, Hôpital Timone Enfants, Marseille, France.

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https://www.medecinesciences.org/10.1051/medsci/201834s206
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http://dx.doi.org/10.1051/medsci/201834s206DOI Listing
November 2018

A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency.

Invest Ophthalmol Vis Sci 2018 09;59(11):4355-4361

Equipe Mitolab, Institut Mitovasc, Centre National de la Recherche Scientifique 6015, Institut National de la Santé et de la Recherche Médicale (INSERM) U1083, Université d'Angers, Angers, France.

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http://dx.doi.org/10.1167/iovs.18-24938DOI Listing
September 2018

Retinal Neuronal Loss in Visually Asymptomatic Patients With Myoclonic Epilepsy With Ragged-Red Fibers.

J Neuroophthalmol 2019 Mar;39(1):18-22

Department of Visual Neurosciences (RPN, DM), Singapore Eye Research Institute, The Academia, Singapore; Ophthalmology and Visual Sciences Program (RPN, DM), Duke-NUS Medical School, Singapore; Departments of Ophthalmology, Biochemistry and Genetics (PR, AC, VP, PA-B and DM), Angers University Hospital, Angers, France; Department of Neuro-Ophthalmology (DM), Singapore National Eye Centre, Singapore; and Department of Surgery (Ophthalmology) (HM), Melbourne Medical School, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1097/WNO.0000000000000690DOI Listing
March 2019

Study of mitochondrial function in placental insufficiency.

Placenta 2018 07 17;67:1-7. Epub 2018 May 17.

MitoVasc Institute, UMR CNRS 6015, INSERM U1083, Angers, France; Department of Neonatal Medicine, CHU Angers, Angers, France. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2018.05.007DOI Listing
July 2018

Iron deficiency without anemia is responsible for decreased left ventricular function and reduced mitochondrial complex I activity in a mouse model.

Int J Cardiol 2018 Sep;266:206-212

Département Anesthésie Réanimation, CHU Angers, 4 rue Larrey, 49100 Angers, France; Institut MITOVASC, INSERM 1083, CNRS 6015, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.02.021DOI Listing
September 2018

The accumulation of assembly intermediates of the mitochondrial complex I matrix arm is reduced by limiting glucose uptake in a neuronal-like model of MELAS syndrome.

Biochim Biophys Acta Mol Basis Dis 2018 May 14;1864(5 Pt A):1596-1608. Epub 2018 Feb 14.

UMR CNRS 6015-INSERM U1083, MitoVasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.02.005DOI Listing
May 2018

How Can a Ketogenic Diet Improve Motor Function?

Front Mol Neurosci 2018 26;11:15. Epub 2018 Jan 26.

INSERM 1083, CNRS, Equipe Mitolab, Institut MITOVASC, UMR 6015, Université d'Angers, Angers, France.

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http://dx.doi.org/10.3389/fnmol.2018.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790787PMC
January 2018

Primary fibroblasts derived from sporadic amyotrophic lateral sclerosis patients do not show ALS cytological lesions.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 31;19(5-6):446-456. Epub 2018 Jan 31.

b MitoLab Unit , MITOVASC Institute, CNRS 6015, INSERM U1083, University of Angers , Angers Cedex 9 , France.

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http://dx.doi.org/10.1080/21678421.2018.1431787DOI Listing
August 2018

A Plasma Metabolomic Signature Involving Purine Metabolism in Human Optic Atrophy 1 (OPA1)-Related Disorders.

Invest Ophthalmol Vis Sci 2018 01;59(1):185-195

Equipe Mitolab, Institut MITOVASC, Centre National de la Recherche Scientifique 6015, Institut National de la Santé et de la Recherche Médicale U1083, Université d'Angers, Angers, France.

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http://dx.doi.org/10.1167/iovs.17-23027DOI Listing
January 2018

Current mechanistic insights into the CCCP-induced cell survival response.

Biochem Pharmacol 2018 02 22;148:100-110. Epub 2017 Dec 22.

MitoLab, Mitochondrial Medicine Research Centre, UMR CNRS 6015-INSERM 1083, Institut MitoVasc, University of Angers, 49933 Angers, France. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.12.018DOI Listing
February 2018

Novel gene mutation in an atypical late-onset mitochondrial form of multifocal dystonia.

Neurol Genet 2017 Dec 11;3(6):e205. Epub 2017 Dec 11.

UMR CNRS 6015-INSERM U1083 (C.B., V.D.-D., N.G., D.G., M.B., D.B., P.A.-B., G.L., P.R., V.P.), Mitovasc Institute, Angers University, France; Department of Biochemistry and Genetics (C.B., V.D.-D., N.G., D.G., M.B., D.B., P.A.-B., G.L., P.R., V.P.), University Hospital of Angers, France; Department of Neurology (T.R.), University Hospital of Nantes, France; and CHU Reims (A.-S.L.), Hôpital Maison Blanche, Pole de biologie, Service de génétique, France.

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http://dx.doi.org/10.1212/NXG.0000000000000205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733248PMC
December 2017

Predicting the pathogenicity of novel variants in mitochondrial tRNA with MitoTIP.

PLoS Comput Biol 2017 12 11;13(12):e1005867. Epub 2017 Dec 11.

Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1371/journal.pcbi.1005867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739504PMC
December 2017

Neurotoxicity of Insecticides.

Curr Med Chem 2017 ;24(27):2988-3001

Département de Biochimie et Génétique, Centre Hospitalier Universitaire, 4 rue Larrey, Angers, F-49933. France.

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http://dx.doi.org/10.2174/0929867324666170526122654DOI Listing
October 2017

Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy.

J Cell Mol Med 2017 10 4;21(10):2284-2297. Epub 2017 Apr 4.

PREMMi/Mitochondrial Medicine Research Centre, Institut MITOVASC, CNRS UMR 6015, INSERM U1083, Université d'Angers, CHU d'Angers, Angers, France.

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http://dx.doi.org/10.1111/jcmm.13149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618673PMC
October 2017

Targeted Metabolomics Reveals Early Dominant Optic Atrophy Signature in Optic Nerves of Opa1delTTAG/+ Mice.

Invest Ophthalmol Vis Sci 2017 02;58(2):812-820

Pôle de Recherche et d'Enseignement en Médecine Mitochondriale (PREMMi), Institut MITOVASC, Université d'Angers, Angers, France 2Département de Biochimie et Génétique, Centre Hospitalier Universitaire, Angers, France.

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http://dx.doi.org/10.1167/iovs.16-21116DOI Listing
February 2017

A Nontargeted UHPLC-HRMS Metabolomics Pipeline for Metabolite Identification: Application to Cardiac Remote Ischemic Preconditioning.

Anal Chem 2017 02 6;89(3):2138-2146. Epub 2017 Jan 6.

PREMMi, Pôle de Recherche et d'Enseignement en Médecine Mitochondriale, Institut MITOVASC, CNRS 6214, INSERM U1083, Université d'Angers , 4 Rue Larrey, 49933 Angers CEDEX 9, France.

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http://pubs.acs.org/doi/10.1021/acs.analchem.6b04912
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http://dx.doi.org/10.1021/acs.analchem.6b04912DOI Listing
February 2017

The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model.

Biochim Biophys Acta Mol Basis Dis 2017 01 1;1863(1):284-291. Epub 2016 Nov 1.

UMR CNRS 6214-INSERM U1083, Mitovasc Institute, Angers University, Angers, France; Biochemistry and Genetics Department, Angers Hospital, F-49000, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.10.028DOI Listing
January 2017

Increased mitochondrial fusion in a autosomal recessive CMT2A family with mitochondrial GTPase mitofusin 2 mutations.

J Peripher Nerv Syst 2016 12;21(4):365-369

PREMMi/Mitochondrial Medicine Research Centre, Institut MITOVASC, CNRS UMR 6214, INSERM U1083, Université d'Angers, CHU d'Angers, Angers, France.

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http://dx.doi.org/10.1111/jns.12192DOI Listing
December 2016

Ovarian ageing: the role of mitochondria in oocytes and follicles.

Hum Reprod Update 2016 11 25;22(6):725-743. Epub 2016 Aug 25.

PREMMi/Pôle de Recherche et d'Enseignement en Médecine Mitochondriale, Institut MITOVASC, CNRS 6214, INSERM U1083, Université d'Angers, Angers, France.

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http://dx.doi.org/10.1093/humupd/dmw028DOI Listing
November 2016

Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone.

Arterioscler Thromb Vasc Biol 2016 08 2;36(8):1598-606. Epub 2016 Jun 2.

From the MITOVASC Institute, CNRS UMR 6214, INSERM U1083 (G.K., C.R., A.A., B.T., L.G., L.L., P.A., V.P., D.H.) and EA 3860 Cardioprotection Remodelage et Thrombose, University of Angers, Angers, France (S.T., F.P.); Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville (M.B., B.E.I.); University Hospital Angers, Angers, France (G.K., P.R., P.A., V.P.); Department of Clinical Neurobiology, University Hospital and German Cancer Research Center Heidelberg, Heidelberg, Germany (H.M.); Institut für Physiologie, Universität zu Lübeck and Deutsches Zentrum für Herz-Kreislauf-Forschung, Lübeck, Germany (C.d.W.); Institute of Interdisciplinary Research, IRIBHM, Université Libre de Bruxelles, Gosselies, Belgium (J.-M.B., B.R.); and Departments of Pathology and Immunology and Medical Specializations - Cardiology, University of Geneva, Geneva, Switzerland (B.R.K.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350073PMC
August 2016

High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant.

Biochim Biophys Acta 2016 Aug 4;1857(8):1336-1343. Epub 2016 Mar 4.

Center for Mitochondrial and Epigenomic Medicine, The Children's Hospital of Philadelphia, Department of Pathology and Laboratory of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbabio.2016.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893908PMC
August 2016

OPA1-related disorders: Diversity of clinical expression, modes of inheritance and pathophysiology.

Neurobiol Dis 2016 Jun 23;90:20-6. Epub 2015 Aug 23.

Centre Hospitalier Universitaire, Département de Biochimie et Génétique, Angers, France; UMR CNRS 6214-INSERM 1083, Université d'Angers, Angers, France. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.08.015DOI Listing
June 2016

Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency.

Int J Biochem Cell Biol 2015 Aug 27;65:91-103. Epub 2015 May 27.

Angers University, Angers, France; Biochemistry and Genetics Laboratory, CHU Angers, F-49000, France; UMR CNRS 6214-INSERM U1083, Angers F-49000, France. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2015.05.017DOI Listing
August 2015

Mutation in NDUFA13/GRIM19 leads to early onset hypotonia, dyskinesia and sensorial deficiencies, and mitochondrial complex I instability.

Hum Mol Genet 2015 Jul 21;24(14):3948-55. Epub 2015 Apr 21.

Institut des Neurosciences de Montpellier, Université de Montpellier I et II, BP 74103, 34 091 Montpellier Cedex 5, France, Service de Neuropédiatrie, CHU Gui de Chauliac, 34 295 Montpellier, France,

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http://dx.doi.org/10.1093/hmg/ddv133DOI Listing
July 2015

mtDNA Variation and Analysis Using Mitomap and Mitomaster.

Curr Protoc Bioinformatics 2013 Dec;44:1.23.1-26

Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA; Department of Pathology and Laboratory Medicine; University of Pennsylvania, Philadelphia, PA; phone: 1-267-425-3078; fax: 1-267-426-0978.

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http://dx.doi.org/10.1002/0471250953.bi0123s44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257604PMC
December 2013

Loss-of-function mutations in WDR73 are responsible for microcephaly and steroid-resistant nephrotic syndrome: Galloway-Mowat syndrome.

Am J Hum Genet 2014 Dec 13;95(6):637-48. Epub 2014 Nov 13.

Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche 1163, Laboratory of Inherited Kidney Diseases, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Imagine Institute, 75015 Paris, France; Department of Genetics, Necker Hospital, Assistance Publique - Hôpitaux de Paris, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259970PMC
December 2014

Improved locus-specific database for OPA1 mutations allows inclusion of advanced clinical data.

Hum Mutat 2015 Jan 1;36(1):20-5. Epub 2014 Dec 1.

CNRS 6214/INSERM 1083, Angers University, Angers, France; Department of Biochemistry and Genetics, University Hospital, Angers, France.

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http://doi.wiley.com/10.1002/humu.22703
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http://dx.doi.org/10.1002/humu.22703DOI Listing
January 2015

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming.

Proc Natl Acad Sci U S A 2014 Sep 5;111(38):E4033-42. Epub 2014 Sep 5.

Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia and the Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1414028111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183335PMC
September 2014

Determinants of flow-mediated outward remodeling in female rodents: respective roles of age, estrogens, and timing.

Arterioscler Thromb Vasc Biol 2014 Jun 3;34(6):1281-9. Epub 2014 Apr 3.

From the LUNAM (L'université Nantes, Le Mans et Angers) University and University of Angers, Angers, France (K.T., B.T., V.P., L.G., D.H.); Centre National de la Recherche Scientifique 6214, Angers, France (A.L.G., L.L., D.H.); Institut National de la Santé et de la Recherche Médicale (INSERM) U1083, Angers, France (D.H.); Centre Hospitalo-Universitaire d'Angers, Angers, France (E.V., V.P., D.H.); and INSERM U1048, Toulouse III Paul Sabatier University, CHU de Toulouse, Toulouse, France (F.L., J.F.A.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303404DOI Listing
June 2014

Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection.

Eur J Pharmacol 2014 Jan 22;723:322-9. Epub 2013 Nov 22.

Department of Pharmacology, School of Medicine, University of California at Irvine, Irvine, CA 92697-4625 USA.

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http://dx.doi.org/10.1016/j.ejphar.2013.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028038PMC
January 2014

Dual effects of resveratrol on arterial damage induced by insulin resistance in aged mice.

J Gerontol A Biol Sci Med Sci 2014 Mar 22;69(3):260-9. Epub 2013 Jun 22.

PharmD, Viva Team-EA 4466, Faculty of Pharmacy, Paris Descartes University, Sorbonne Paris Cité 75006, Paris Cedex, France.

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http://dx.doi.org/10.1093/gerona/glt081DOI Listing
March 2014

Dominant optic atrophy.

Orphanet J Rare Dis 2012 Jul 9;7:46. Epub 2012 Jul 9.

Institut des Neurosciences de Montpellier, U1051 de l'INSERM, Université de Montpellier I et II, BP 74103, F-34091 Montpellier cedex 05, France.

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http://dx.doi.org/10.1186/1750-1172-7-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526509PMC
July 2012

Toward a mtDNA locus-specific mutation database using the LOVD platform.

Hum Mutat 2012 Sep 2;33(9):1352-8. Epub 2012 Jul 2.

Mitochondrial Research Group, Institute for Ageing and Health, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1002/humu.22118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394605PMC
September 2012

Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.

PLoS One 2011 17;6(8):e23295. Epub 2011 Aug 17.

Department of Pathology, The Paul F. Glenn Labs for the Biological Mechanisms of Aging, Harvard Medical School, Boston, Massachusetts, United States of America.

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August 2011

Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.

FASEB J 2011 May 1;25(5):1618-27. Epub 2011 Feb 1.

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May 2011