Vincent Pasque

Vincent Pasque

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Vincent Pasque

Vincent Pasque

Publications by authors named "Vincent Pasque"

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Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming.

Genome Res 2019 Oct 12;29(10):1659-1672. Epub 2019 Sep 12.

KU Leuven-University of Leuven, Department of Development and Regeneration, Leuven Stem Cell Institute, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1101/gr.249706.119DOI Listing
October 2019

Tox4 modulates cell fate reprogramming.

J Cell Sci 2019 Sep 13. Epub 2019 Sep 13.

KU Leuven - University of Leuven, Department of Development and Regeneration, Herestraat 49, B-3000 Leuven, Belgium

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http://dx.doi.org/10.1242/jcs.232223DOI Listing
September 2019

Murine iPSC-derived microglia and macrophage cell culture models recapitulate distinct phenotypical and functional properties of classical and alternative neuro-immune polarisation.

Brain Behav Immun 2019 Sep 13. Epub 2019 Sep 13.

Laboratory of Experimental Hematology, University of Antwerp, Antwerp, Belgium; Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2019.09.009DOI Listing
September 2019

Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation.

Front Cell Dev Biol 2019 3;7:169. Epub 2019 Sep 3.

Department of Development and Regeneration, Leuven Stem Cell Institute, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fcell.2019.00169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733891PMC
September 2019

X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels.

Stem Cell Reports 2019 Feb 10;12(2):333-350. Epub 2019 Jan 10.

KU Leuven - University of Leuven, Department of Development and Regeneration, Leuven Stem Cell Institute, Leuven Cancer Institute, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372905PMC
February 2019

Dynamics of DNA Methylation Reprogramming Influenced by X Chromosome Dosage in Induced Pluripotent Stem Cells.

Epigenet Insights 2018 14;11:2516865718802931. Epub 2018 Oct 14.

Leuven Stem Cell Institute, Leuven Cancer Institute, Department of Development and Regeneration, KU Leuven - University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1177/2516865718802931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233964PMC
October 2018

Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue.

J Vis Exp 2018 06 21(136). Epub 2018 Jun 21.

Department of Molecular, Cell and Developmental Biology, UCLA; Department of Biological Chemistry, David Geffen School of Medicine; Molecular Biology Institute Interdepartmental Program, UCLA;

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http://dx.doi.org/10.3791/57760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101961PMC
June 2018

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.

Stem Cell Reports 2018 05 19;10(5):1537-1550. Epub 2018 Apr 19.

Department of Biological Chemistry, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, David Geffen School of Medicine, University of California Los Angeles, 615 Charles E. Young Drive South, BSRB 390D, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995367PMC
May 2018

X chromosome reactivation in reprogramming and in development.

Curr Opin Cell Biol 2015 Dec 11;37:75-83. Epub 2015 Nov 11.

Department of Biological Chemistry, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688236PMC
December 2015

X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency.

Cell 2014 Dec;159(7):1681-97

Department of Biological Chemistry, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282187PMC
December 2014

Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming.

Mol Cell 2014 Aug 24;55(4):524-36. Epub 2014 Jul 24.

Wellcome Trust/Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QN, UK; Department of Zoology, University of Cambridge, Cambridge CB2 1QN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765140053
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http://dx.doi.org/10.1016/j.molcel.2014.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156308PMC
August 2014

Mitosis gives a brief window of opportunity for a change in gene transcription.

PLoS Biol 2014 Jul 29;12(7):e1001914. Epub 2014 Jul 29.

Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, United Kingdom; Department of Zoology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1001914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114836PMC
July 2014

A new route to human embryonic stem cells.

Nat Med 2013 Jul;19(7):820-1

California Institute for Regenerative Medicine, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nm.3266DOI Listing
July 2013

Nuclear reprogramming.

Development 2013 Jun;140(12):2468-71

The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN, UK.

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http://dx.doi.org/10.1242/dev.092049DOI Listing
June 2013

Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes.

Nucleus 2011 Nov-Dec;2(6):533-9. Epub 2011 Nov 1.

Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.4161/nucl.2.6.17799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324342PMC
May 2012

Epigenetic factors influencing resistance to nuclear reprogramming.

Trends Genet 2011 Dec 21;27(12):516-25. Epub 2011 Sep 21.

Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

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http://dx.doi.org/10.1016/j.tig.2011.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814186PMC
December 2011

Epigenetic reprogramming: is deamination key to active DNA demethylation?

Reproduction 2011 Nov 12;142(5):621-32. Epub 2011 Sep 12.

Wellcome Trust/Cancer Research UK Gurdon Institute, Cambridge, CB2 1QN, UK.

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http://dx.doi.org/10.1530/REP-11-0148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863514PMC
November 2011

Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?

Nat Rev Mol Cell Biol 2011 06 23;12(7):453-9. Epub 2011 Jun 23.

Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

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http://dx.doi.org/10.1038/nrm3140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657683PMC
June 2011

Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes.

Genes Dev 2011 May;25(9):946-58

Wellcome Trust, Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom.

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http://dx.doi.org/10.1101/gad.615211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084028PMC
May 2011

Histone variant macroH2A confers resistance to nuclear reprogramming.

EMBO J 2011 May 6;30(12):2373-87. Epub 2011 May 6.

Wellcome Trust Cancer Research UK Gurdon Institute, Cambridge, UK.

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http://dx.doi.org/10.1038/emboj.2011.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116279PMC
May 2011

Zebrafish Sox7 and Sox18 function together to control arterial-venous identity.

Dev Biol 2008 May 7;317(2):405-16. Epub 2008 Feb 7.

GIGA-Research - Unité de Biologie Moléculaire et Génie Génétique, Tour B34, Université de Liège, B-4000 Sart Tilman, Belgium.

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http://dx.doi.org/10.1016/j.ydbio.2008.01.028DOI Listing
May 2008