Ville Leinonen

Ville Leinonen

UNVERIFIED PROFILE

Are you Ville Leinonen?   Register this Author

Register author
Ville Leinonen

Ville Leinonen

Publications by authors named "Ville Leinonen"

Are you Ville Leinonen?   Register this Author

81Publications

1650Reads

43Profile Views

Surgery for degenerative cervical spine disease in Finland, 1999-2015.

Acta Neurochir (Wien) 2019 Oct 1;161(10):2147-2159. Epub 2019 Jun 1.

Centre for Health and Social Economics, National Institute for Health and Welfare, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00701-019-03958-6DOI Listing
October 2019

CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics.

J Neurol Neurosurg Psychiatry 2019 Oct 5;90(10):1117-1123. Epub 2019 Jun 5.

Hydrocephalus Research Unit, Department of clinical neuroscience, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2019-320826DOI Listing
October 2019

Surgical techniques for degenerative cervical spine in Finland from 1999 to 2015.

Acta Neurochir (Wien) 2019 Oct 10;161(10):2161-2173. Epub 2019 Aug 10.

Unit of Clinical Neuroscience, Neurosurgery, University of Oulu and Medical Research Center, Oulu University Hospital, Oulu, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00701-019-04026-9DOI Listing
October 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Long-Term Outcome of Spinal Cord Stimulation in Failed Back Surgery Syndrome: 20 Years of Experience With 224 Consecutive Patients.

Neurosurgery 2019 May;84(5):1011-1018

Neurosurgery of KUH NeuroCenter, Kuopio, Kuopio University Hospital, and Faculty of Health Sciences, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuros/nyy194DOI Listing
May 2019

Copy number loss in is common among Finnish and Norwegian patients with iNPH.

Neurol Genet 2018 Dec 3;4(6):e291. Epub 2018 Dec 3.

Department of Neurosurgery (V.E.K., A. Jokinen, I.J., J.-M.L., A. Junkkari, J.E.J., V.L.), Kuopio University Hospital and University of Eastern Finland; Institute of Clinical Medicine-Neurology (S.H., M.H., H. Soininen, A.M.K.), University of Eastern Finland, Kuopio; Department of Neurosurgery (M.O., K.L.), University of Helsinki and Helsinki University Hospital; Clinical Neurosciences (C.A., A.K., J.F., J.R.), Department of Neurosurgery, University of Turku and Turku University Hospital; Department of Neurosurgery (A.R.), Tampere University Hospital; Unit of Clinical Neuroscience (M. Kauppinen, V.L.), Neurosurgery, University of Oulu and Medical Research Center, Oulu University Hospital; Institute of Biomedicine (M.H.), University of Eastern Finland, Kuopio; Analytical and Translational Genetics Unit (M. Kurki), Department of Medicine, Massachusetts General Hospital; Program in Medical and Population Genetics (M. Kurki), Broad Institute of MIT and Harvard; Stanley Center for Psychiatric Research (M. Kurki), Broad Institute for Harvard and MIT; Department of Neurology (H. Sato, T.K.), Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Japan; Medical Research Center (A.M.R.), Oulu University Hospital, Finland; Unit of Clinical Neuroscience (A.M.R.), Neurology, University of Oulu, Finland; Department of Neurosurgery (P.K.E.), Oslo University Hospital-Rikshospitalet; and Institute of Clinical Medicine (P.K.E.), Faculty of Medicine, University of Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/NXG.0000000000000291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283454PMC
December 2018

Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients.

Acta Neuropathol Commun 2018 10 1;6(1):102. Epub 2018 Oct 1.

Center for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Novum 5th floor, SE-141 57, Huddinge, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-018-0605-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166280PMC
October 2018

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.

J Alzheimers Dis 2017 ;60(3):1077-1085

Institute of Clinical Medicine -Neurosurgery, University of Eastern Finland and Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170583DOI Listing
May 2018

Raised intracranial pressure and brain edema.

Handb Clin Neurol 2017 ;145:25-37

Department of Pathology, Institute of Clinical Medicine, University of Eastern Finland and Department of Pathology, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-802395-2.00004-3DOI Listing
January 2018

Cerebrospinal fluid circulation and hydrocephalus.

Handb Clin Neurol 2017 ;145:39-50

Department of Pathology, Institute of Clinical Medicine, University of Eastern Finland and Department of Pathology, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-802395-2.00005-5DOI Listing
January 2018

Rate and Risk Factors for Shunt Revision in Pediatric Patients with Hydrocephalus-A Population-Based Study.

World Neurosurg 2017 May 14;101:615-622. Epub 2017 Feb 14.

Department of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2017.02.030DOI Listing
May 2017

Selling vs. non-selling neuro-oncology research cohorts and manuscripts in the eyes of a grumpy reviewer after 2,000 reviews.

Acta Neurochir (Wien) 2017 Jan 7;159(1):3-6. Epub 2016 Apr 7.

UEF Neurosurgery, Neurosurgery of KUH NeuroCenter, KUH Neuro-Oncology Group and CyberKnife, Kuopio Intracranial Aneurysm Patient and Family Database, Clinical Research Grant Board of Finnish Cancer Society, Acta Neurochirurgica Editorial Board, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00701-016-2787-3DOI Listing
January 2017

Associations of intracranial pressure with brain biopsy, radiological findings, and shunt surgery outcome in patients with suspected idiopathic normal pressure hydrocephalus.

Acta Neurochir (Wien) 2017 01 23;159(1):51-61. Epub 2016 Nov 23.

Neurosurgery of NeuroCenter, Kuopio University Hospital and University of Eastern Finland, P.O. Box 100, 70029, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00701-016-3025-8DOI Listing
January 2017

Implantable RF-coil with multiple electrodes for long-term EEG-fMRI monitoring in rodents.

J Neurosci Methods 2016 12 21;274:154-163. Epub 2016 Oct 21.

Department of Neurobiology, A.I. Virtanen Institute for Molecular Medicine, University of Eastern Finland, 70211, Kuopio, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jneumeth.2016.10.014DOI Listing
December 2016

Risk of Shunting After Aneurysmal Subarachnoid Hemorrhage: A Collaborative Study and Initiation of a Consortium.

Stroke 2016 10 15;47(10):2488-96. Epub 2016 Sep 15.

From the Department of Neurosurgery, NeuroCenter, Kuopio University Hospital, Finland (H.A., V.L., J. Huttunen, T.S., A.L., J.F., M.F., T.K., J.E.J., T.J.H.); Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas (V.S.B., S.G.A., B.G.W.); and Department of Neurosurgery, Helsinki University Hospital, Finland (J. Hernesniemi).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/STROKEAHA.116.013739DOI Listing
October 2016

Familial idiopathic normal pressure hydrocephalus.

J Neurol Sci 2016 Sep 25;368:11-8. Epub 2016 Jun 25.

Department of Neurosurgery, Kuopio University Hospital, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jns.2016.06.052DOI Listing
September 2016

SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

J Cell Sci 2016 06 15;129(11):2224-38. Epub 2016 Apr 15.

Institute of Biomedicine, School of Medicine, University of Eastern Finland, 70211 Kuopio, Finland Institute of Clinical Medicine - Neurology, School of Medicine, University of Eastern Finland and Department of Neurology, Kuopio University Hospital, 70211 Kuopio, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.185215DOI Listing
June 2016

Sub-classification based specific movement control exercises are superior to general exercise in sub-acute low back pain when both are combined with manual therapy: A randomized controlled trial.

BMC Musculoskelet Disord 2016 Mar 22;17:135. Epub 2016 Mar 22.

Department of Physical and Rehabilitation Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12891-016-0986-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804617PMC
March 2016

Feasibility of radiological markers in idiopathic normal pressure hydrocephalus.

Acta Neurochir (Wien) 2015 Oct 21;157(10):1709-18; discussion 1719. Epub 2015 Jul 21.

Neurosurgery of NeuroCenter, Kuopio University Hospital and University of Eastern Finland, P.O. Box 100, FIN-70029, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s00701-015-2503
Web Search
http://link.springer.com/10.1007/s00701-015-2503-8
Publisher Site
http://dx.doi.org/10.1007/s00701-015-2503-8DOI Listing
October 2015

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.

J Alzheimers Dis 2015 ;43(2):565-73

Institute of Clinical Medicine - Neurology, University of Eastern Finland, and Department of Neurology, Kuopio University Hospital, Kuopio, Finland Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-140777DOI Listing
July 2015

Analysis of disruptive events and precarious situations caused by interaction with neurosurgical microscope.

Acta Neurochir (Wien) 2015 Jul 12;157(7):1147-54. Epub 2015 May 12.

School of Computing, University of Eastern Finland, 80101, Joensuu, Finland,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00701-015-2433-5DOI Listing
July 2015

Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers.

Front Neurol 2015 8;6:153. Epub 2015 Jul 8.

Center for Neuroscience and Cell Biology (CNC), University of Coimbra , Coimbra , Portugal ; Neurochemistry Laboratory, Neurology Department, Coimbra University Hospital , Coimbra , Portugal ; Faculty of Medicine, University of Coimbra , Coimbra , Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2015.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495343PMC
July 2015

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Neurobiol Aging 2015 Feb 6;36(2):1221.e15-28. Epub 2014 Sep 6.

Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.09.003DOI Listing
February 2015

Association between bone mineral density and lumbar disc degeneration.

Maturitas 2014 Dec 22;79(4):449-55. Epub 2014 Sep 22.

Bone and Cartilage Research Unit, Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Department of Orthopedics, Traumatology and Hand Surgery, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03785122140029
Publisher Site
http://dx.doi.org/10.1016/j.maturitas.2014.09.003DOI Listing
December 2014

Association of Modic changes with health-related quality of life among patients referred to spine surgery.

Scand J Pain 2014 Jan 1;5(1):36-40. Epub 2014 Jan 1.

Institute of Clinical Medicine, Department of Physical and Rehabilitation Medicine, University of Oulu, and Medical Research Center Oulu, Oulu, Finland.

View Article

Download full-text PDF

Source
http://www.degruyter.com/view/j/sjpain.2014.5.issue-1/j.sjpa
Publisher Site
http://dx.doi.org/10.1016/j.sjpain.2013.08.003DOI Listing
January 2014

Education of research ethics for clinical investigators with Moodle tool.

BMC Med Ethics 2013 Dec 12;14:53. Epub 2013 Dec 12.

Research Ethics Committee/Science Service Center, Kuopio University Hospital, P,O BOX 100, Kuopio FI-70029 KYS, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1472-6939-14-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867673PMC
December 2013

APOE4 predicts amyloid-β in cortical brain biopsy but not idiopathic normal pressure hydrocephalus.

J Neurol Neurosurg Psychiatry 2012 Nov 6;83(11):1119-24. Epub 2012 Sep 6.

Neurosurgery of NeuroCentre, Kuopio University Hospital, P.O. box 1777, 70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2011-303849DOI Listing
November 2012

Cortical brain biopsy in long-term prognostication of 468 patients with possible normal pressure hydrocephalus.

Neurodegener Dis 2012 10;10(1-4):166-9. Epub 2012 Feb 10.

Department of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000335155DOI Listing
August 2012

Efficacy of movement control exercises versus general exercises on recurrent sub-acute nonspecific low back pain in a sub-group of patients with movement control dysfunction. Protocol of a randomized controlled trial.

BMC Musculoskelet Disord 2012 Apr 11;13:55. Epub 2012 Apr 11.

Department of Physical and Rehabilitation Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2474-13-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353835PMC
April 2012

Visual and quantitative assessment of lateral lumbar spinal canal stenosis with magnetic resonance imaging.

Acta Radiol 2011 Nov 3;52(9):1024-31. Epub 2011 Oct 3.

University of Eastern Finland, School of Medicine, Institute of Clinical Medicine, Department of Clinical Radiology, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1258/ar.2011.110083DOI Listing
November 2011

Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus.

Int J Alzheimers Dis 2011 1;2011:312526. Epub 2011 Jun 1.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4061/2011/312526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109737PMC
July 2011

Immunohistochemical visualization of amyloid-beta protein precursor and amyloid-beta in extra- and intracellular compartments in the human brain.

J Alzheimers Dis 2010 ;20(4):1015-28

Department of Clinical Medicine, Unit of Neurology, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-2010-091681DOI Listing
October 2010

Dynamic surface electromyographic responses in chronic low back pain treated by traditional bone setting and conventional physical therapy.

J Manipulative Physiol Ther 2007 Jan;30(1):31-7

University of Kuopio, Department of Physiology, P.O. Box 1627, 70211 Kuopio [corrected], Finland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016147540600309
Publisher Site
http://dx.doi.org/10.1016/j.jmpt.2006.11.010DOI Listing
January 2007

Postural control in male patients with hip osteoarthritis.

Gait Posture 2006 Jan 18;23(1):45-50. Epub 2005 Jan 18.

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, PO Box 1777, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gaitpost.2004.11.017DOI Listing
January 2006

Back and neck extensor loading and back pain provocation in urban bus drivers with and without low back pain.

Pathophysiology 2005 Dec 11;12(4):249-55. Epub 2005 Oct 11.

Department of Physiology, Kuopio University Hospital, P.O. Box 1777, FIN-70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pathophys.2005.09.004DOI Listing
December 2005

Wireless on-line electromyography in recording neck muscle function: a pilot study.

Pathophysiology 2005 Dec 26;12(4):303-6. Epub 2005 Oct 26.

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, 70200 Kuopio, Finland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09284680050010
Publisher Site
http://dx.doi.org/10.1016/j.pathophys.2005.09.012DOI Listing
December 2005

Lumbar paraspinal muscle function, perception of lumbar position, and postural control in disc herniation-related back pain.

Spine (Phila Pa 1976) 2003 Apr;28(8):842-8

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://pdfs.journals.lww.com/spinejournal/2003/04150/Lumbar_
Web Search
April 2003

Paraspinal muscle responses during sudden upper limb loading.

Eur J Appl Physiol 2002 Nov 14;88(1-2):42-9. Epub 2002 Aug 14.

Department of Physiology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00421-002-0664-7
Publisher Site
http://dx.doi.org/10.1007/s00421-002-0664-7DOI Listing
November 2002

Impaired lumbar movement perception in association with postural stability and motor- and somatosensory-evoked potentials in lumbar spinal stenosis.

Spine (Phila Pa 1976) 2002 May;27(9):975-83

Department of Physical and Rehabilitation Medicine, Kuopio University Hospital, University of Kuopio, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/00007632-200205010-00019DOI Listing
May 2002