Publications by authors named "Vikram Mehraj"

66Publications

The anti-inflammatory IL-37/SIGIRR axis is functionally compromised in HIV infection.

AIDS 2019 09;33(11):1693-1703

Laboratory of Innate Immunity, CHU Ste-Justine Research Center/Department of Microbiology, Infectious Diseases & Immunology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000002271DOI Listing
September 2019

Use of (1→3)-β-d-glucan for diagnosis and management of invasive mycoses in HIV-infected patients.

Mycoses 2018 Oct 5;61(10):718-722. Epub 2018 Jul 5.

Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/myc.12797
Publisher Site
http://dx.doi.org/10.1111/myc.12797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175469PMC
October 2018

Anti-Gag antibodies gag HIV infection and slow disease progression.

AIDS 2018 06;32(10):1373-1375

CHUM/Department of Microbiology, Infectious Diseases & Immunology, University of Montreal, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000001852DOI Listing
June 2018

HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation.

PLoS One 2018 30;13(3):e0194185. Epub 2018 Mar 30.

Laboratory of Innate Immunity, CHU Ste-Justine Research Center/Department of Microbiology, Infectious Diseases & Immunology, University of Montreal, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194185PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877838PMC
July 2018

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.

AIDS Res Treat 2018 9;2018:7645125. Epub 2018 Jan 9.

Division of Pediatric Respiratory Medicine, McGill University Health Center Research Institute, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/7645125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818882PMC
January 2018

Very early antiretroviral therapy permits CD8 T cells to keep HIV reservoirs at bay.

Ann Transl Med 2017 Nov;5(21):434

Research Institute, McGill University Health Centre, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://atm.amegroups.com/article/view/16450/17556
Publisher Site
http://dx.doi.org/10.21037/atm.2017.08.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690957PMC
November 2017

Characterization of myeloid cell populations in human testes collected after sex reassignment surgery.

J Reprod Immunol 2018 02 14;125:16-24. Epub 2017 Oct 14.

Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada; Chronic Viral Illness Service and Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jri.2017.10.043DOI Listing
February 2018

Potential contribution of gut microbiota and systemic inflammation on HIV vaccine effectiveness and vaccine design.

AIDS Res Ther 2017 Sep 12;14(1):48. Epub 2017 Sep 12.

Research Institute of the McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://aidsrestherapy.biomedcentral.com/articles/10.1186/s12
Publisher Site
http://dx.doi.org/10.1186/s12981-017-0164-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594512PMC
September 2017

Plasma Level of Soluble ST2 in Chronically Infected HIV-1 Patients with Suppressed Viremia.

Open AIDS J 2017 26;11:32-35. Epub 2017 Apr 26.

Research Institute and Chronic Viral Illness Service of the McGill University Health Center, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1874613601711010032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427803PMC
April 2017

A potentially protective role of IL-18 Binding Protein in HIV-infected Long-Term Non-Progressors.

Cytokine 2017 02 16;90:96-99. Epub 2016 Nov 16.

Laboratory of Innate Immunity, Centre Hospitalier Universitaire (CHU) Ste-Justine Research Center/Department of Microbiology, Infectiology & Immunology, University of Montreal, Montreal, Quebec, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2016.10.018DOI Listing
February 2017

HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy.

AIDS 2017 01;31(1):35-48

aCHUM-Research Centre bDepartment of Microbiology, Infectiology and Immunology, Faculty of Medicine, Université de Montréal cInstitut de Recherche Clinique de Montréal, Montréal, Québec, Canada dUniversity of California Davis, Davis, California, USA eChronic Viral Illness Service and Research Institute fDivision of Gastroenterology and Hepatology gDivision of Hematology, McGill University Health Centre, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000001309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131694PMC
January 2017

Baseline Naive CD4+ T-cell Level Predicting Immune Reconstitution in Treated HIV-infected Late Presenters.

Chin Med J (Engl) 2016 11;129(22):2683-2690

Division of Hematology, Research Institute and Chronic Viral Illness Service, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0366-6999.193460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126159PMC
November 2016

The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy.

Int J Tryptophan Res 2016 12;9:67-77. Epub 2016 Oct 12.

Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada.; Postdoctoral Fellow, The Research Institute of the McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/IJTR.S38355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063567PMC
October 2016

Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults.

AIDS 2016 11;30(18):2777-2786

aDepartment of Biological Sciences and BioMed Research Centre, Université du Québec à Montréal (UQAM) bChronic Viral Illness Service and Research Institute, McGill University Health Centre cFaculty of Medicine, McGill University dDepartment of Microbiology, Infectiology and Immunology, Faculty of Medicine, Université de Montréal, and Centre de recherche du CHUM eMetropolitan Centre for Plastic Surgery, Montreal, Québec fDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario gDivision of Hematology, McGill University Health Centre, Montreal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000001282DOI Listing
November 2016

The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response.

EBioMedicine 2016 Jul 1;9:37-44. Epub 2016 Jul 1.

Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Chronic Viral Illness Service, McGill University Health Centre, Montréal, Québec, Canada; Division of Hematology, McGill University Health Centre, Montréal, Québec, Canada. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S23523964163030
Publisher Site
http://dx.doi.org/10.1016/j.ebiom.2016.06.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972565PMC
July 2016

Combination antiretroviral therapy and indoleamine 2,3-dioxygenase in HIV infections: challenges and new opportunities.

AIDS 2016 07;30(11):1839-41

aLaboratory of Innate Immunity, Centre Hospitalier Universitaire (CHU) Staine-Justine Research Center bDepartment of Microbiology, Infectiology and Immunology cCentre Hospitalier Universite de Montreal (CHUM) dUniversity of Montreal eMcGill University Health Center, McGill University fDepartment of Biological Sciences, University of Quebec at Montreal (UQAM), Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000001168DOI Listing
July 2016

The plasma levels of soluble ST2 as a marker of gut mucosal damage in early HIV infection.

AIDS 2016 06;30(10):1617-27

aResearch Institute of the McGill University Health CentrebChronic Viral Illness Service, McGill University Health CentrecDepartment of Biological Sciences and BioMed Research Centre, Université du Québec à Montréal (UQAM)dDepartment of Family Medicine, McGill UniversityeClinique Médicale l'ActuelfClinique Médicale Quartier LatingClinique Médicale OPUShCentre de recherche du Centre Hospitalier de l'Université de MontréaliDépartement de Microbiologie, Infectiologie et Immunologie, Université de MontréaljDivision of Hematology, McGill University Health Centre, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QAD.0000000000001105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900419PMC
June 2016

Reversing Gut Damage in HIV Infection: Using Non-Human Primate Models to Instruct Clinical Research.

EBioMedicine 2016 Feb 26;4:40-9. Epub 2016 Jan 26.

Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada; Chronic Viral Illness Service, McGill University Health Centre, Montreal, Quebec, Canada; Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2016.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776249PMC
February 2016

Elevation and persistence of CD8 T-cells in HIV infection: the Achilles heel in the ART era.

J Int AIDS Soc 2016 3;19(1):20697. Epub 2016 Mar 3.

Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779330PMC
http://dx.doi.org/10.7448/IAS.19.1.20697DOI Listing
September 2016

Imbalanced production of IL-18 and its antagonist in human diseases, and its implications for HIV-1 infection.

Cytokine 2016 06 16;82:38-51. Epub 2016 Feb 16.

Laboratory of Innate Immunity, Canada; CHU-Sainte-Justine Research Center, Canada; Department of Microbiology, Infectiology & Immunology, Canada; University of Montreal, Montreal, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2016.01.006DOI Listing
June 2016

Current topics in HIV pathogenesis, part 2: Inflammation drives a Warburg-like effect on the metabolism of HIV-infected subjects.

Cytokine Growth Factor Rev 2016 Apr 27;28:1-10. Epub 2016 Jan 27.

INRS-Institut Armand Frappier, Laval, Quebec H7V 1B7, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cytogfr.2016.01.001DOI Listing
April 2016

HIV immunotherapy comes of age: implications for prevention, treatment and cure.

Expert Rev Clin Immunol 2016 2;12(2):91-4. Epub 2015 Dec 2.

b Research Institute of the McGill University Health Centre: Glen site , Montréal , QC , Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/1744666X.2016.1112269DOI Listing
November 2016

Antiretroviral Therapy in Primary HIV-1 Infection: Influences on Immune Activation and Gut Mucosal Barrier Dysfunction.

AIDS Rev 2015 Jul-Sep;17(3):135-46

Chronic Viral Illness Service, McGill University Health Centre, Montreal, Canada.

View Article

Download full-text PDF

Source
August 2016

Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients.

J Acquir Immune Defic Syndr 2016 Mar;71(3):254-62

*Chronic Viral Illnesses Service, McGill University Health Centre, Montreal, Quebec, Canada; †Currently, Département des Sciences Biologiques et Centre de recherche BioMed, Université du Québec à Montréal (UQAM), Québec, Canada; ‡Research Institute McGill University Health Centre, Montreal, Quebec, Canada; §Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; ‖Research Department, School of Medicine, Universidad Iberoamericana, Santo Domingo, Dominican Republic; and ¶Division of Hematology, McGill University Health Centre, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
https://insights.ovid.com/crossref?an=00126334-201603010-000
Publisher Site
http://dx.doi.org/10.1097/QAI.0000000000000859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770371PMC
March 2016

Overcoming the challenge of diagnosis of early HIV infection: a stepping stone to optimal patient management.

Expert Rev Anti Infect Ther 2015 ;13(10):1189-93

b 2 Research Institute of the McGill University Health Centre: Glen site, Montréal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14787210.2015.1077701DOI Listing
June 2016

Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests.

Int J Tryptophan Res 2015 4;8:41-8. Epub 2015 Aug 4.

Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada. ; Research Institute of the McGill University Health Centre, Montreal, QC, Canada. ; Division of Hematology, McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/IJTR.S26862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527356PMC
August 2015

Clinical Relevance of Kynurenine Pathway in HIV/AIDS: An Immune Checkpoint at the Crossroads of Metabolism and Inflammation.

AIDS Rev 2015 Apr-Jun;17(2):96-106

Department of Biological Sciences and Center for Biomedical Research, Université du Québec à Montréal (UQAM), Montreal, QC, Canada.

View Article

Download full-text PDF

Source
February 2016

HIV and the gut microbiota, partners in crime: breaking the vicious cycle to unearth new therapeutic targets.

J Immunol Res 2015 22;2015:614127. Epub 2015 Feb 22.

Chronic Viral Illness Service, McGill University Health Centre, 3650 Saint Urbain, Montreal, QC, Canada H2X 2P4 ; Research Institute, McGill University Health Centre, Montreal, QC, Canada H3H 2R9 ; Division of Hematology, McGill University Health Centre, 687 Pine Avenue West, Montreal, QC, Canada H3A 1A1.

View Article

Download full-text PDF

Source
http://www.hindawi.com/journals/jir/2015/614127/
Publisher Site
http://dx.doi.org/10.1155/2015/614127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352503PMC
December 2015

Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy.

Open AIDS J 2014 29;8:66-78. Epub 2014 Dec 29.

Chronic Viral Illness Service, McGill University Health Centre, Montreal, QC, Canada ; Research Institute, McGill University Health Centre, Montreal, QC, Canada ; Division of Hematology, McGill University Health Centre, Montreal, QC, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1874613601408010066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302459PMC
January 2015

Advances and applications of molecular cloning in clinical microbiology.

Biotechnol Genet Eng Rev 2014 Oct;30(1-2):65-78

a Faculty of Agrobiology, Department of Genetics and Breeding , Czech University of Life Sciences , Prague , Czech Republic.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02648725.2014.921501DOI Listing
October 2014

Early sex-specific modulation of the molecular clock in trauma.

J Trauma Acute Care Surg 2014 Jan;76(1):241-4

From the Equipe Infection (V.M., C.C., M.L., J.-L.M., J.T.), Genre et Grossesse, URMITE CNRS UMR7278, INSERM U1095, Aix- Marseille Université; Service d'anesthésie et de reanimation (S.W., M.L., J.T.), Hôpital Nord, Assistance Publique - Hôpitaux de Marseille, Aix Marseille Université; and Service d'anesthésie et de reanimation (S.W.), Réanimation du centre des brûlés inter-régional de Méditerranée, Hôpital de la Conception, Assistance Publique - Hôpitaux de Marseille, Marseille, France.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/TA.0b013e3182a90014DOI Listing
January 2014

Professionalism in medical students at a private medical college in Karachi, Pakistan.

J Pak Med Assoc 2013 Jul;63(7):935-9

Research Associate, Aga Khan University, Karachi Pakistan. 8Universite de la Mediterranee, Faculte de Medecine, 27 Bid. Jean Moulin, Marseille, France.

View Article

Download full-text PDF

Source
July 2013

Serene threonine kinase 39 gene single nucleotide A-G polymorphism rs35929607 is weakly associated with essential hypertension in population of Tharparkar, Pakistan.

J Pak Med Assoc 2013 Feb;63(2):199-205

Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan.

View Article

Download full-text PDF

Source
February 2013

Monocyte responses in the context of Q fever: from a static polarized model to a kinetic model of activation.

J Infect Dis 2013 Sep 24;208(6):942-51. Epub 2013 Jun 24.

Aix-Marseille University, URMITE, CNRS UMR 7278, IRD 198, INSERM 1095, Marseille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jit266DOI Listing
September 2013

Chronic hepatitis E virus infection is specifically associated with an interferon-related transcriptional program.

J Infect Dis 2013 Jan 16;207(1):125-32. Epub 2012 Oct 16.

Centre de Néphrologie et Transplantation Rénale, Fédération de Bactériologie-Virologie-Hygiène, Assistance Publique - Hôpitaux de Marseille, Marseille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jis632DOI Listing
January 2013

Overexpression of the Per2 gene in male patients with acute Q fever.

J Infect Dis 2012 Dec 14;206(11):1768-70. Epub 2012 Sep 14.

Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, Aix-Marseille Université, Marseille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jis600DOI Listing
December 2012

The ligands of Numb proteins X1 and X2 are specific markers for chronic Q fever.

FEMS Immunol Med Microbiol 2012 Feb;64(1):98-100

URMITE, CNRS UMR 6236-IRD 198, Université de la Méditerranée, Marseille Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1574-695X.2011.00860.xDOI Listing
February 2012

Macrophage polarization and bacterial infections.

Curr Opin Infect Dis 2011 Jun;24(3):230-4

Unité de Recherche sur les Maladies Infectieuses Tropicales et Emergentes, Centre National de la Recherche Scientifique Unité Mixte de Recherche 6236, Institut Fédératif de Recherche 48, Université de la Méditerranée, Marseille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/QCO.0b013e328344b73eDOI Listing
June 2011

Trends in undergraduate teaching of parasitology in medical schools of Pakistan.

J Pak Med Assoc 2010 Aug;60(8):613-7

Department of Pathology & Microbiology, Aga Khan University, Stadium Road, Pakistan.

View Article

Download full-text PDF

Source
August 2010

Increase in isolation of extended spectrum beta lactamase producing multidrug resistant non typhoidal Salmonellae in Pakistan.

BMC Infect Dis 2010 Apr 22;10:101. Epub 2010 Apr 22.

Department of Pathology and Microbiology, Aga Khan University, Karachi, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2334-10-101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872654PMC
April 2010

Evaluation of two ELISA assay kits against RT-PCR for diagnosis of dengue virus infection in a hospital setting in Karachi, Pakistan.

J Pak Med Assoc 2009 Jun;59(6):390-4

Department of Pathology & Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, Pakistan.

View Article

Download full-text PDF

Source
June 2009

Trends in Mycobacterium tuberculosis resistance, Pakistan, 1990-2007.

Int J Infect Dis 2009 Nov 14;13(6):e377-82. Epub 2009 Apr 14.

Department of Pathology and Microbiology, Aga Khan University, Stadium Road, Karachi, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijid.2009.01.008DOI Listing
November 2009

Are we prepared to meet the growing challenges of disasters?

J Ayub Med Coll Abbottabad 2007 Oct-Dec;19(4):140-1

View Article

Download full-text PDF

Source
October 2008

Knowledge, attitudes and practices of health care workers regarding needle stick injuries at a tertiary care hospital in Pakistan.

J Pak Med Assoc 2008 Feb;58(2):57-60

Department of Pathology and Microbiology, Aga Khan University, Karachi.

View Article

Download full-text PDF

Source
February 2008