Vijaya Ramesh

Vijaya Ramesh

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Vijaya Ramesh

Vijaya Ramesh

Publications by authors named "Vijaya Ramesh"

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46Publications

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A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

Neuro Oncol 2016 09 6;18(9):1278-87. Epub 2016 Mar 6.

Department of Neurosurgery (F.N., S.-i.E., M.H., N.L., D.P.C., S.D.R., R.L.M., H.W.), Center for Human Genetic Research (M.F.J., V.R.), Department of Neuropathology (A.S.-R.), Division of Neuro-Oncology (P.K.B.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.1093/neuonc/now031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998993PMC
September 2016

Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.

Neurobiol Dis 2015 Oct 24;82:22-31. Epub 2015 May 24.

Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070799PMC
http://dx.doi.org/10.1016/j.nbd.2015.04.018DOI Listing
October 2015

Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder.

Mol Autism 2013 Mar 20;4(1). Epub 2013 Mar 20.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/2040-2392-4-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610211PMC
March 2013

Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types.

Mol Cancer Res 2012 May 16;10(5):649-59. Epub 2012 Mar 16.

Center for Human Genetic Research, Massachusetts General Hospital, Richard B. Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-11-0425-TDOI Listing
May 2012

Assessment of Immunomodulatory Activity of Euphorbia hirta L.

Indian J Pharm Sci 2010 Sep;72(5):621-5

Department of Botany, Quaid-e-Millath Government Arts College, Chennai-600 002, India.

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http://dx.doi.org/10.4103/0250-474X.78532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116308PMC
September 2010

Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas.

BMC Med Genomics 2009 Jul 9;2:42. Epub 2009 Jul 9.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1186/1755-8794-2-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716362PMC
July 2009

Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas.

Clin Cancer Res 2009 Mar 10;15(6):1940-6. Epub 2009 Mar 10.

Center for Human Genetic Research, Massachusetts General Hospital, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701205PMC
March 2009

Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.

Nat Med 2008 Aug 22;14(8):843-8. Epub 2008 Jun 22.

Department of Neurobiology, Brain Research Institute, University of California, Los Angeles, 695 Charles E. Young Drive South, Los Angeles, California 90095, USA.

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http://www.nature.com/articles/nm1788
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http://dx.doi.org/10.1038/nm1788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664098PMC
August 2008

Pam (Protein associated with Myc) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling.

Cell Signal 2008 Jun 1;20(6):1084-91. Epub 2008 Feb 1.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.cellsig.2008.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435383PMC
June 2008

Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth.

Neurobiol Dis 2008 Feb 19;29(2):278-92. Epub 2007 Sep 19.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Richard B. Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.nbd.2007.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266821PMC
February 2008

Role of NHERF1, cystic fibrosis transmembrane conductance regulator, and cAMP in the regulation of aquaporin 9.

J Biol Chem 2008 Feb 30;283(5):2986-96. Epub 2007 Nov 30.

Center for Systems Biology, Program in Membrane Biology/Nephrology Division, Simches Research Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1074/jbc.M704678200DOI Listing
February 2008

Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation.

J Biol Chem 2007 Nov 11;282(44):32152-7. Epub 2007 Sep 11.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston 02114, and Department of Cell Biology, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1074/jbc.M706592200DOI Listing
November 2007

Functions of MUC16 in corneal epithelial cells.

Invest Ophthalmol Vis Sci 2007 Oct;48(10):4509-18

Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1167/iovs.07-0430DOI Listing
October 2007

Preparation and drug release activity of scaffolds containing collagen and poly(caprolactone).

J Biomed Mater Res A 2006 Oct;79(1):153-8

Department of Bionanosystem Engineering, Chonbuk National University, Chonju 56-756, Republic of Korea.

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http://dx.doi.org/10.1002/jbm.a.30715DOI Listing
October 2006

Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulation.

Biochem Biophys Res Commun 2006 Sep 31;348(3):826-31. Epub 2006 Jul 31.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.07.126DOI Listing
September 2006

Alternative splicing in protein associated with Myc (Pam) influences its binding to c-Myc.

J Neurosci Res 2006 Feb;83(2):222-32

Molecular Neurogenetics Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1002/jnr.20723DOI Listing
February 2006

Inactivation patterns of NF2 and DAL-1/4.1B (EPB41L3) in sporadic meningioma.

Cancer Genet Cytogenet 2005 Oct;162(2):135-9

Department of Neurology, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2005.04.003DOI Listing
October 2005

Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin.

Exp Cell Res 2005 Aug;308(1):177-87

Howard Hughes Medical Institute, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.yexcr.2005.04.017DOI Listing
August 2005

The NF2 tumor suppressor Merlin and the ERM proteins interact with N-WASP and regulate its actin polymerization function.

J Biol Chem 2005 Apr 7;280(13):12517-22. Epub 2005 Feb 7.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1074/jbc.C400583200DOI Listing
April 2005

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2.

Oncogene 2004 Nov;23(54):8815-25

Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1038/sj.onc.1208110DOI Listing
November 2004

Sacrococcygeal chordomas in patients with tuberous sclerosis complex show somatic loss of TSC1 or TSC2.

Genes Chromosomes Cancer 2004 Sep;41(1):80-5

Tumour Molecular Genetics Group, Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK.

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http://dx.doi.org/10.1002/gcc.20052DOI Listing
September 2004

TorsinB--perinuclear location and association with torsinA.

J Neurochem 2004 Jun;89(5):1186-94

Departments of Neurology and Radiology, Molecular Neurogenetics Unit, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02404.xDOI Listing
June 2004

Merlin and the ERM proteins in Schwann cells, neurons and growth cones.

Authors:
Vijaya Ramesh

Nat Rev Neurosci 2004 Jun;5(6):462-70

Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/nrn1407DOI Listing
June 2004

A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migration.

J Cell Sci 2004 Jun 25;117(Pt 14):2951-61. Epub 2004 May 25.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1242/jcs.01156DOI Listing
June 2004

The early onset dystonia protein torsinA interacts with kinesin light chain 1.

J Biol Chem 2004 May 17;279(19):19882-92. Epub 2004 Feb 17.

Molecular Neurogenetics Unit, Departments of Neurology and Radiology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1074/jbc.M401332200DOI Listing
May 2004

Phosphorylation of tuberin as a novel mechanism for somatic inactivation of the tuberous sclerosis complex proteins in brain lesions.

Cancer Res 2004 Feb;64(3):812-6

Molecular Neurogenetics Unit, Molecular Neuro-Oncology, and Department of Neurology, Harvard Medical School/Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1158/0008-5472.can-03-3277DOI Listing
February 2004

Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.

J Biol Chem 2004 Jan 14;279(2):1351-8. Epub 2003 Oct 14.

Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1074/jbc.M310208200DOI Listing
January 2004

A 34 bp deletion within TSC2 is a rare polymorphism, not a pathogenic mutation.

Ann Hum Genet 2003 Nov;67(Pt 6):495-503

Hematology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1046/j.1529-8817.2003.00059.xDOI Listing
November 2003

Distribution and ultrastructural localization of torsinA immunoreactivity in the human brain.

Brain Res 2003 Oct;986(1-2):12-21

Neurology Service, Massachusetts General Hospital and Harvard Medical School, CNY 114-2300, 114 16th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0006-8993(03)03164-0DOI Listing
October 2003

TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress.

J Neurosci Res 2003 Apr;72(2):158-68

Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital, and Neuroscience Program, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/jnr.10567DOI Listing
April 2003

The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton.

J Biol Chem 2002 Nov 10;277(46):44180-6. Epub 2002 Sep 10.

Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown 02129, USA.

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http://dx.doi.org/10.1074/jbc.M207211200DOI Listing
November 2002