Vijay Kumar Kutala

Vijay Kumar Kutala

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Vijay Kumar Kutala

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Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Clin Pharmacol Ther 2019 Jun 17;105(6):1477-1491. Epub 2019 Feb 17.

General Medicine and Hypertension Unit, Department of Medicine, University of Verona, Verona, Italy.

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http://doi.wiley.com/10.1002/cpt.1323
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http://dx.doi.org/10.1002/cpt.1323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542461PMC
June 2019

Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases.

Pharmacol Rep 2019 Jun 11;71(3):385-392. Epub 2019 Jan 11.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1016/j.pharep.2019.01.006DOI Listing
June 2019

Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia.

Cancer Chemother Pharmacol 2019 May 26;83(5):875-880. Epub 2019 Feb 26.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1007/s00280-019-03803-8DOI Listing
May 2019

Dual Effect of IL-6 -174 G/C Polymorphism and Promoter Methylation in the Risk of Coronary Artery Disease Among South Indians.

Indian J Clin Biochem 2019 Apr 21;34(2):180-187. Epub 2018 Feb 21.

1Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Punjagutta, Hyderabad, Telangana India.

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http://dx.doi.org/10.1007/s12291-018-0740-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486910PMC
April 2019

Impact of pharmacogenetics on statin-induced myopathy in South-Indian subjects.

Indian Heart J 2018 Dec 10;70 Suppl 3:S120-S125. Epub 2018 Aug 10.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India.

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http://dx.doi.org/10.1016/j.ihj.2018.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309567PMC
December 2018

Machine learning algorithm-based risk prediction model of coronary artery disease.

Mol Biol Rep 2018 Oct 11;45(5):901-910. Epub 2018 Jul 11.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1007/s11033-018-4236-2DOI Listing
October 2018

Artificial neural network model for predicting the bioavailability of tacrolimus in patients with renal transplantation.

PLoS One 2018 5;13(4):e0191921. Epub 2018 Apr 5.

Departments of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences Hyderabad, Telangana, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191921PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886400PMC
July 2018

Impact of eNOS 27-bp VNTR (4b/a) gene polymorphism with the risk of Systemic Lupus Erythematosus in south Indian subjects.

Gene 2018 Jun 8;658:105-112. Epub 2018 Mar 8.

Departments of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Telangana, Hyderabad, India. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.03.021DOI Listing
June 2018

Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.

J Genet 2018 Jun;97(2):523-537

Center of Excellence in Biotechnology Research King Saud University Riyadh Saudi Arabia.

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June 2018

Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity.

Free Radic Biol Med 2017 12 5;113:530-538. Epub 2017 Nov 5.

Radiation Biology & Health Sciences Division, Modular Laboratories, Bhabha Atomic Research Centre, Trombay, Mumbai, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08915849173116
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http://dx.doi.org/10.1016/j.freeradbiomed.2017.10.378DOI Listing
December 2017

Neuro-fuzzy model of homocysteine metabolism.

J Genet 2017 Dec;96(6):919-926

Biochemical Genetics Division, Sandor Life Sciences Pvt Ltd, Hyderabad 500 043, India.

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December 2017

Epistatic interactions among CYP2C19*2, CYP3A4 and GSTP1 on the cyclophosphamide therapy in lupus nephritis patients.

Pharmacogenomics 2017 Oct 4;18(15):1401-1411. Epub 2017 Oct 4.

Department of Clinical Immunology & Rheumatology, Nizam's Institute of Medical Sciences, Hyderabad 500082, India.

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http://dx.doi.org/10.2217/pgs-2017-0069DOI Listing
October 2017

Association of GSTT1 and GSTM1 polymorphisms in South Indian Epilepsy Patients.

Indian J Exp Biol 2016 Nov;54(11):783-7

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November 2016

In silico approaches to identify the potential inhibitors of glutamate carboxypeptidase II (GCPII) for neuroprotection.

J Theor Biol 2016 10 16;406:137-42. Epub 2016 Jul 16.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad 500082, India.

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http://dx.doi.org/10.1016/j.jtbi.2016.07.016DOI Listing
October 2016

Population-level diversity in the association of genetic polymorphisms of one-carbon metabolism with breast cancer risk.

J Community Genet 2016 Oct 19;7(4):279-290. Epub 2016 Aug 19.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, 500082, India.

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http://dx.doi.org/10.1007/s12687-016-0277-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138163PMC
October 2016

Endothelial Dysfunction in Type 2 Diabetes Mellitus.

Indian J Clin Biochem 2016 Oct 29;31(4):372-9. Epub 2015 Sep 29.

Department of Clinical Pharmacology and Therapeutics (Biochemistry), Nizam's Institute of Medical Sciences, Hyderabad, Telangana India.

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http://dx.doi.org/10.1007/s12291-015-0516-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992481PMC
October 2016

Artificial neural network-based pharmacogenomic algorithm for warfarin dose optimization.

Pharmacogenomics 2016 15;17(2):121-31. Epub 2015 Dec 15.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad 500082, India.

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http://dx.doi.org/10.2217/pgs.15.161DOI Listing
September 2016

Development of neuro-fuzzy model to explore gene-nutrient interactions modulating warfarin dose requirement.

Pharmacogenomics 2016 08 27;17(12):1315-25. Epub 2016 Jul 27.

Department of Clinical Pharmacology & Therapeutics Nizam's Institute of Medical Sciences, Hyderabad 500082, India.

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http://dx.doi.org/10.2217/pgs-2016-0058DOI Listing
August 2016

Assessment of Oxidative Stress Markers and Carotid Artery Intima-Media Thickness in Elderly Patients Without and with Coronary Artery Disease.

Indian J Clin Biochem 2016 Jul 6;31(3):278-85. Epub 2015 Oct 6.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Punjagutta, Hyderabad, 500082 India.

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http://dx.doi.org/10.1007/s12291-015-0530-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910848PMC
July 2016

Association of CTLA4 exon-1 polymorphism with the tumor necrosis factor-α in the risk of systemic lupus erythematosus among South Indians.

Hum Immunol 2016 Feb 12;77(2):158-64. Epub 2015 Nov 12.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Hyderabad, Telangana, India. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2015.11.002DOI Listing
February 2016

Mechanistic insights into the effect of CYP2C9*2 and CYP2C9*3 variants on the 7-hydroxylation of warfarin.

Pharmacogenomics 2015 ;16(4):393-400

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India.

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http://dx.doi.org/10.2217/pgs.14.185DOI Listing
January 2016

Comparative analysis of four disease prediction models of Parkinson's disease.

Mol Cell Biochem 2016 Jan 5;411(1-2):127-34. Epub 2015 Oct 5.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, India.

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http://dx.doi.org/10.1007/s11010-015-2574-0DOI Listing
January 2016

Clinical utility of genetic variants of glutamate carboxypeptidase II in predicting breast cancer and prostate cancer risk.

Cancer Genet 2015 Nov 8;208(11):552-8. Epub 2015 Sep 8.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1016/j.cancergen.2015.09.001DOI Listing
November 2015

Association of Aberrations in One Carbon Metabolism with Intimal Medial Thickening in Patients with Type 2 Diabetes Mellitus.

Indian J Clin Biochem 2015 Jul 26;30(3):263-70. Epub 2014 Jul 26.

Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, 500 082 Andhra Pradesh India.

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http://dx.doi.org/10.1007/s12291-014-0458-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469063PMC
July 2015

Structure, function, and epigenetic regulation of BNIP3: a pathophysiological relevance.

Mol Biol Rep 2014 Nov 6;41(11):7705-14. Epub 2014 Aug 6.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1007/s11033-014-3664-xDOI Listing
November 2014

Molecular mechanism of interaction of mitocurcumin-1 with Akt1 and STAT3: an in silico approach.

Indian J Biochem Biophys 2014 Aug;51(4):308-13

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August 2014

Sexual dimorphism in xenobiotic genetic variants-mediated risk for Parkinson's disease.

Neurol Sci 2014 Jun 4;35(6):897-903. Epub 2014 Jan 4.

Centre for Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, India.

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http://dx.doi.org/10.1007/s10072-013-1622-3DOI Listing
June 2014

Methodological issues in the development of a pharmacogenomic algorithm for warfarin dosing: comparison of two regression approaches.

Pharmacogenomics 2014 Jun;15(8):1125-32

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, 500082, India.

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https://www.futuremedicine.com/doi/10.2217/pgs.14.59
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http://dx.doi.org/10.2217/pgs.14.59DOI Listing
June 2014

Association of seven functional polymorphisms of one-carbon metabolic pathway with total plasma homocysteine levels and susceptibility to Parkinson's disease among South Indians.

Neurosci Lett 2014 May 28;568:1-5. Epub 2014 Mar 28.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2014.03.044DOI Listing
May 2014

Association of Parkinson's disease with altered serum levels of lead and transition metals among South Indian subjects.

Indian J Biochem Biophys 2014 Apr;51(2):121-6

Centre for Biotechnology, Jawaharlal Nehru Technological University, Hyderabad.

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April 2014

Impact of hyperhomocysteinemia on breast cancer initiation and progression: epigenetic perspective.

Cell Biochem Biophys 2014 Mar;68(2):397-406

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Panjagutta, Hyderabad, 500082, Andhra Pradesh, India.

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http://dx.doi.org/10.1007/s12013-013-9720-7DOI Listing
March 2014

Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: association with serological markers and six functional polymorphisms of one-carbon metabolic pathway.

Gene 2014 Feb 12;536(1):45-52. Epub 2013 Dec 12.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Hyderabad 500082, India. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2013.11.094DOI Listing
February 2014

Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease.

Cell Biochem Biophys 2013 Nov;67(2):353-61

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, 500082, Andhra Pradesh, India.

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http://dx.doi.org/10.1007/s12013-011-9322-1DOI Listing
November 2013

GCPII modulates oxidative stress and prostate cancer susceptibility through changes in methylation of RASSF1, BNIP3, GSTP1 and Ec-SOD.

Mol Biol Rep 2013 Oct 24;40(10):5541-50. Epub 2013 Aug 24.

Departments of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Panjagutta, Hyderabad, 500082, India.

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http://dx.doi.org/10.1007/s11033-013-2655-7DOI Listing
October 2013

Association of family history of type 2 diabetes mellitus with markers of endothelial dysfunction in South Indian population.

Indian J Biochem Biophys 2013 Apr;50(2):93-8

Dept of Biochemistry, ACS Medical College & Hospital, Chennai, India.

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April 2013

Oxidative stress in coronary artery disease: epigenetic perspective.

Mol Cell Biochem 2013 Feb 17;374(1-2):203-11. Epub 2012 Nov 17.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, 500082, Andhra Pradesh, India.

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http://dx.doi.org/10.1007/s11010-012-1520-7DOI Listing
February 2013

Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer.

Mol Carcinog 2012 Oct 15;51 Suppl 1:E32-41. Epub 2011 Nov 15.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, Andhra Pradesh, India.

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http://dx.doi.org/10.1002/mc.21830DOI Listing
October 2012

Role of CYP1A1 haplotypes in modulating susceptibility to coronary artery disease.

Indian J Biochem Biophys 2012 Oct;49(5):349-55

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad 500082, India.

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October 2012

Glutamate carboxypeptidase II (GCPII) genetic variants as determinants of hyperhomocysteinemia: implications in stroke susceptibility.

Indian J Biochem Biophys 2012 Oct;49(5):356-62

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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October 2012

Genetic variants of thiopurine and folate metabolic pathways determine 6-MP-mediated hematological toxicity in childhood ALL.

Pharmacogenomics 2012 Jul;13(9):1001-8

Department of Medical Oncology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, Andhra Pradesh, PIN 500082, India.

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http://dx.doi.org/10.2217/pgs.12.70DOI Listing
July 2012

Retrospective evidence for clinical validity of expanded genetic model in warfarin dose optimization in a South Indian population.

Pharmacogenomics 2012 Jun;13(8):869-78

Departments of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.2217/pgs.12.62DOI Listing
June 2012

Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast.

Mol Cell Biochem 2012 Feb 11;361(1-2):189-95. Epub 2011 Oct 11.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, Andhra Pradesh, India.

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http://link.springer.com/10.1007/s11010-011-1103-z
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http://dx.doi.org/10.1007/s11010-011-1103-zDOI Listing
February 2012

Cross-talk between one-carbon metabolism and xenobiotic metabolism: implications on oxidative DNA damage and susceptibility to breast cancer.

Cell Biochem Biophys 2011 Dec;61(3):715-23

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad 500082, Andhra Pradesh, India.

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http://link.springer.com/10.1007/s12013-011-9245-x
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http://dx.doi.org/10.1007/s12013-011-9245-xDOI Listing
December 2011

Epistatic interactions between loci of one-carbon metabolism modulate susceptibility to breast cancer.

Mol Biol Rep 2011 Nov 14;38(8):4893-901. Epub 2010 Dec 14.

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad 500082, Andhra Pradesh, India.

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http://link.springer.com/10.1007/s11033-010-0631-z
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http://dx.doi.org/10.1007/s11033-010-0631-zDOI Listing
November 2011

Advances in biomedical sciences. Preface.

Indian J Biochem Biophys 2011 Aug;48(4):211-2

VUmc, University Medical Center, Amsterdam, The Netherlands.

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August 2011

Modulatory effect of plasma folate and polymorphisms in one-carbon metabolism on catecholamine methyltransferase (COMT) H108L associated oxidative DNA damage and breast cancer risk.

Indian J Biochem Biophys 2011 Aug;48(4):283-9

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences (NIMS), Panjagutta, Hyderabad 500082, AP, India.

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August 2011

Aberrations in one-carbon metabolism induce oxidative DNA damage in sporadic breast cancer.

Mol Cell Biochem 2011 Mar 27;349(1-2):159-67. Epub 2010 Nov 27.

Department of Clinical Pharmacology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, Andhra Pradesh, India.

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http://link.springer.com/content/pdf/10.1007/s11010-010-0670
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http://link.springer.com/10.1007/s11010-010-0670-8
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http://dx.doi.org/10.1007/s11010-010-0670-8DOI Listing
March 2011

Oxidative stress in cardiovascular disease.

Indian J Biochem Biophys 2009 Dec;46(6):421-40

Department of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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December 2009

Nitric oxide production and nitric oxide synthase type 2 expression by cotton rat (Sigmodon hispidus) macrophages reflect the same pattern as human macrophages.

Dev Comp Immunol 2009 May 18;33(5):718-24. Epub 2009 Jan 18.

Department of Veterinary Biosciences, The Ohio State University, 1925 Coffey Road, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.dci.2008.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852107PMC
May 2009

Measurement of oxygenation at the site of stem cell therapy in a murine model of myocardial infarction.

Adv Exp Med Biol 2008 ;614:45-52

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, 420 W. 12th Ave, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/978-0-387-74911-2_6DOI Listing
April 2008

Reactivity of superoxide anion radical with a perchlorotriphenylmethyl (trityl) radical.

J Phys Chem B 2008 Jan 15;112(1):158-67. Epub 2007 Dec 15.

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1021/jp076656xDOI Listing
January 2008

Cardioprotection by sulfaphenazole, a cytochrome p450 inhibitor: mitigation of ischemia-reperfusion injury by scavenging of reactive oxygen species.

J Pharmacol Exp Ther 2007 Dec 14;323(3):813-21. Epub 2007 Sep 14.

Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.107.12948
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http://dx.doi.org/10.1124/jpet.107.129486DOI Listing
December 2007

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.

Antioxid Redox Signal 2007 Nov;9(11):1837-49

Department of Internal Medicine, Divisions of Cardiology and Pulmonary, Critical Care, and Sleep Medicine, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1089/ars.2007.1603DOI Listing
November 2007

Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function.

Am J Physiol Heart Circ Physiol 2007 Oct 27;293(4):H2129-39. Epub 2007 Jul 27.

Center for Biomedical Electron Paramagnetic Resonance Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1152/ajpheart.00677.2007DOI Listing
October 2007

Spirulina attenuates cyclosporine-induced nephrotoxicity in rats.

J Appl Toxicol 2006 Sep-Oct;26(5):444-51

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad 500 082, India.

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http://dx.doi.org/10.1002/jat.1159DOI Listing
August 2007

Role of oxygen in postischemic myocardial injury.

Antioxid Redox Signal 2007 Aug;9(8):1193-206

Department of Internal Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1089/ars.2007.1636DOI Listing
August 2007

Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart.

Am J Physiol Heart Circ Physiol 2007 Mar 1;292(3):H1254-61. Epub 2006 Dec 1.

Center for Biomedical Electron Paramagnetic Resonance Spectroscopy and Imaging, Division of Cardiothoracic Surgery, Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1152/ajpheart.01058.2006DOI Listing
March 2007

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK.

Cancer Biol Ther 2007 Feb 5;6(2):178-84. Epub 2007 Feb 5.

Davis Heart and Lung Research Institute and Comprehensive Cancer Center, Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852522PMC
http://dx.doi.org/10.4161/cbt.6.2.3577DOI Listing
February 2007

Protection against cisplatin-induced nephrotoxicity by Spirulina in rats.

Cancer Chemother Pharmacol 2006 Dec 22;58(6):802-8. Epub 2006 Mar 22.

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, 500 082, Hyderabad, India.

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http://dx.doi.org/10.1007/s00280-006-0231-8DOI Listing
December 2006

Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol.

J Cardiovasc Pharmacol 2006 Sep;48(3):79-87

Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, and Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.

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https://insights.ovid.com/crossref?an=00005344-200609000-000
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http://dx.doi.org/10.1097/01.fjc.0000242050.16790.65DOI Listing
September 2006

Structure-activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia-reperfusion injury.

Bioorg Med Chem 2006 Aug 12;14(16):5510-6. Epub 2006 May 12.

Institute of Organic and Medicinal Chemistry, University of Pécs, Hungary.

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http://dx.doi.org/10.1016/j.bmc.2006.04.040DOI Listing
August 2006

Attenuation of myocardial ischemia-reperfusion injury by trimetazidine derivatives functionalized with antioxidant properties.

J Pharmacol Exp Ther 2006 Jun 8;317(3):921-8. Epub 2006 Feb 8.

Davis Heart and Lung Research Institute, The Ohio State University, 420 W. 12th Ave., Room 114, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1124/jpet.105.100834DOI Listing
June 2006

C-phycocyanin protects against ischemia-reperfusion injury of heart through involvement of p38 MAPK and ERK signaling.

Am J Physiol Heart Circ Physiol 2006 May 22;290(5):H2136-45. Epub 2005 Dec 22.

Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1152/ajpheart.01072.2005DOI Listing
May 2006

C-phycocyanin ameliorates doxorubicin-induced oxidative stress and apoptosis in adult rat cardiomyocytes.

J Cardiovasc Pharmacol 2006 Jan;47(1):9-20

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

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January 2006

Protective effect of Spirulina against doxorubicin-induced cardiotoxicity.

Phytother Res 2005 Dec;19(12):1030-7

Department of Clinical Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, India.

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http://dx.doi.org/10.1002/ptr.1783DOI Listing
December 2005

Lipopolysaccharide-induced alterations in oxygen consumption and radical generation in endothelial cells.

Mol Cell Biochem 2005 Oct;278(1-2):119-27

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s11010-005-6936-xDOI Listing
October 2005

Simultaneous measurement of oxygenation in intracellular and extracellular compartments of lung microvascular endothelial cells.

Antioxid Redox Signal 2004 Jun;6(3):597-603

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1089/152308604773934350DOI Listing
June 2004

Reaction of superoxide with trityl radical: implications for the determination of superoxide by spectrophotometry.

Arch Biochem Biophys 2004 Apr;424(1):81-8

Center for Biomedical EPR Spectroscopy and Imaging, Department of Internal Medicine, Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.abb.2004.01.020DOI Listing
April 2004

EPR oximetry in the beating heart: myocardial oxygen consumption rate as an index of postischemic recovery.

Magn Reson Med 2004 Apr;51(4):835-42

Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1002/mrm.20000DOI Listing
April 2004

In vivo measurement and mapping of skin redox stress induced by ultraviolet light exposure.

Free Radic Biol Med 2004 Mar;36(5):665-72

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Ohio State University College of Medicine, Columbus, OH 43210-1252, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2003.11.024DOI Listing
March 2004

Measurement of oxygen consumption in mouse aortic endothelial cells using a microparticulate oximetry probe.

Arch Biochem Biophys 2003 Dec;420(1):169-75

Department of Internal Medicine, Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.abb.2003.09.008DOI Listing
December 2003

Application of a trityl-based radical probe for measuring superoxide.

Free Radic Biol Med 2003 Dec;35(12):1608-18

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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December 2003