The prognosis of Hodgkin’s lymphoma is
excellent. However late complications like
second malignancy may occur in survivors.
We report here 2 of case of Hodgkin’s
lymphoma who developed papillary
carcinoma thyroid as second malignancy.
Patients underwent surgery and radioactive
iodine(I-131) ablation therapy. These cases
highlight the importance of long term
follow up in Hodgkin’s lymphoma
Introduction The synthetic form of thyroid hormone-tetraiodothyronine is quite useful for the treatment of non-drug
induced hypothyroidism including radioiodine-131 therapy induced hypothyroidism. Attention to certain
aspects is required while the therapy is instituted with this drug.
Objective(s) To highlight the precautions which ensure good therapeutic outcome when levothyroxine is being taken as
thyroid hormone replacement therapy.
Methods Case study method was conducted. In a case of hypothyroidism, the patient had purchased levothyroxine
preparation without its container and did not store it properly. There was failure of therapy. Repurchase of
same drug in its container and its proper storage helped to achieve optimal therapeutic outcome.
Conclusion Synthetic levothyroxine which is used as thyroid hormone replacement therapy is very unstable if exposed to
light and humidity. Further, only very minute amount (in micrograms) being required, any loss of potency
can result in failure of therapy. Therefore, it is essential that the drug should be stored in a dark colored
container with a tight lid away from sunlight and moisture.
Keywords Improper drug handling, Treatment failure, Pharmacology