Dr. Vijai Williams, MD, DM - Gleneagles Global Hospitals - Associate Consultant

Dr. Vijai Williams

MD, DM

Gleneagles Global Hospitals

Associate Consultant

Chennai, Tamil Nadu | India

Main Specialties: Pediatric Critical Care Medicine, Pediatrics

Additional Specialties: Pediatric critical care

ORCID logohttps://orcid.org/0000-0001-6508-9710


Top Author

Dr. Vijai Williams, MD, DM - Gleneagles Global Hospitals - Associate Consultant

Dr. Vijai Williams

MD, DM

Introduction

I work in the field of Pediatric critical care with keen interest in research relating patient oriented outcomes.

Primary Affiliation: Gleneagles Global Hospitals - Chennai, Tamil Nadu , India

Specialties:

Additional Specialties:


View Dr. Vijai Williams’s Resume / CV

Education

Dec 2020
Post Graduate Institute of Medical Education and Research
DM
PEDIATRIC CRITICAL CARE
Jul 2013 - Jun 2016
Post Graduate Institute of Medical Education and Research
M.D.
PEDIATRICS
Dec 2012
Jawaharlal Institute of Postgraduate Medical Education and Research
MBBS

Publications

20Publications

273Reads

161Profile Views

Decompressive craniectomy in pediatric non-traumatic intracranial hypertension: a single center experience.

Br J Neurosurg 2020 Jun 18;34(3):258-263. Epub 2020 Mar 18.

Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1080/02688697.2020.1740648DOI Listing
June 2020
0.947 Impact Factor

Mystery of a Family with Recurrent Male Infant Deaths- Solved by Autopsy and Molecular Tests.

Indian J Pediatr 2020 May 26. Epub 2020 May 26.

Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1007/s12098-020-03304-0DOI Listing
May 2020
0.919 Impact Factor

Acute exogenous lipoid pneumonia presenting as spontaneous air leak following accidental baby oil aspiration.

Trop Doct 2020 Apr 26;50(2):149-152. Epub 2019 Dec 26.

MD, Professor, Division of Pediatric Emergency and Intensive Care, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1177/0049475519896206DOI Listing
April 2020
0.528 Impact Factor

Blood component utilization before and after implementation of good transfusion practice measures in a pediatric emergency department.

Transfus Apher Sci 2020 Apr 9;59(2):102719. Epub 2020 Jan 9.

Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1016/j.transci.2020.102719DOI Listing
April 2020
1.072 Impact Factor

Time of Pediatric Intensive Care Unit Admission and Mortality: A Systematic Review and Meta-Analysis.

J Pediatr Intensive Care 2020 Mar 18;9(1):1-11. Epub 2019 Nov 18.

Department of Pediatrics, Postgraduate Institute of Medical Research and Education, Chandigarh, India.

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http://dx.doi.org/10.1055/s-0039-3399581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978166PMC
March 2020

0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial.

Crit Care 2020 01 2;24(1). Epub 2020 Jan 2.

Division of Pediatric Allergy & Immunology, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education & Research, Chandigarh, India.

Background: Acute kidney injury (AKI) is an important complication encountered during the course of diabetic ketoacidosis (DKA). Plasma-Lyte with lower chloride concentration than saline has been shown to be associated with reduced incidence of AKI in adults with septic shock. No study has compared this in DKA.

Methods: This double-blind, parallel-arm, investigator-initiated, randomized controlled trial compared 0.9% saline with Plasma-Lyte-A as initial fluid in pediatric DKA. The study was done in a tertiary care, teaching, and referral hospital in India in children (>?1?month-12?years) with DKA as defined by ISPAD. Children with cerebral edema or known chronic kidney/liver disease or who had received pre-referral fluids and/or insulin were excluded. Sixty-six children were randomized to receive either Plasma-Lyte (n =?34) or 0.9% saline (n =?32).

Main Outcomes: Primary outcome was incidence of new or progressive AKI, defined as a composite outcome of change in creatinine (defined by KDIGO), estimated creatinine clearance (defined by p-RIFLE), and NGAL levels. The secondary outcomes were resolution of AKI, time to resolution of DKA (pH?>?7.3, bicarbonate>?15?mEq/L & normal sensorium), change in chloride, pH and bicarbonate levels, proportion of in-hospital all-cause mortality, need for renal replacement therapy (RRT), and length of ICU and hospital stay.

Results: Baseline characteristics were similar in both groups. The incidence of new or progressive AKI was similar in both [Plasma-Lyte 13 (38.2%) versus 0.9% saline 15 (46.9%); adjusted OR 1.22; 95% CI 0.43-3.43, p =?0.70]. The median (IQR) time to resolution of DKA in Plasma-Lyte-A and 0.9% saline were 14.5 (12 to 20) and 16 (8 to 20) h respectively. Time to resolution of AKI was similar in both [Plasma-Lyte 22.1 versus 0.9% saline 18.8?h (adjusted HR 1.72; 95% CI 0.83-3.57; p =?0.14)]. Length of hospital stay was also similar in both [Plasma-Lyte 9 (8 to 12) versus 0.9% saline 10 (8.25 to 11) days; p =?0.39].

Conclusions: The incidence of new or progressive AKI and resolution of AKI were similar in both groups. Plasma-Lyte-A was similar to 0.9% Saline in time to resolution of DKA, need for RRT, mortality, and lengths of PICU and hospital stay.

Trial Registration: Clinical trial registry of India, CTRI/2018/05/014042 (ctri.nic.in) (Retrospectively registered).

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http://dx.doi.org/10.1186/s13054-019-2683-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939333PMC
January 2020
6.960 Impact Factor

Fluid Therapy For Pediatric Patients With Diabetic Ketoacidosis: Current Perspectives.

Diabetes Metab Syndr Obes 2019 12;12:2355-2361. Epub 2019 Nov 12.

Division of Pediatric Emergency and Intensive Care, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.2147/DMSO.S194944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858801PMC
November 2019

Frontal pyomucocoele as forehead swelling in a five-year-old girl.

Trop Doct 2019 Oct 16;49(4):316-318. Epub 2019 Jul 16.

Professor, Department of Pediatrics, PGIMER, Chandigarh, India.

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http://dx.doi.org/10.1177/0049475519864249DOI Listing
October 2019
4 Reads
0.528 Impact Factor

What the Mind Does Not Know, the Eyes Do Not See!

Clin Pediatr (Phila) 2019 09 21;58(10):1136-1139. Epub 2019 Jul 21.

1 Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1177/0009922819864589DOI Listing
September 2019
11 Reads
1.261 Impact Factor

Spontaneous intracranial haemorrhage in children-intensive care needs and predictors of in-hospital mortality: a 10-year single-centre experience.

Childs Nerv Syst 2019 08 4;35(8):1371-1379. Epub 2019 Jun 4.

Department of Neurosurgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1007/s00381-019-04209-wDOI Listing
August 2019
115 Reads
1.163 Impact Factor

Phenotypic heterogeneity of kyphoscoliosis with vertebral and rib defects: a case series.

Clin Dysmorphol 2019 Jul;28(3):103-113

Department of Pediatrics, PGIMER, Chandigarh, India.

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http://dx.doi.org/10.1097/MCD.0000000000000269DOI Listing
July 2019
12 Reads
0.416 Impact Factor

Acute Kidney Injury in Children With Diabetic Ketoacidosis: A Real Concern.

Pediatr Crit Care Med 2019 06;20(6):590-591

Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatric Center (APC), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India Department of Pediatrics, Kovai Medical Center and Hospital, Coimbatore, India Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatric Center (APC), Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1097/PCC.0000000000001928DOI Listing
June 2019
20 Reads
2.338 Impact Factor

Congenital Bathing Trunk Nevus with Meningomyelocele.

Indian Dermatol Online J 2019 Mar-Apr;10(2):186-187

Department of Pediatrics, PGIMER, Chandigarh, India.

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http://dx.doi.org/10.4103/idoj.IDOJ_256_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434768PMC
April 2019
9 Reads

Fc-gamma receptor expression profile in a North-Indian cohort of pediatric-onset systemic lupus erythematosus: An observational study.

Int J Rheum Dis 2019 Mar 6;22(3):449-457. Epub 2018 Nov 6.

Pediatric Allergy and Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://doi.wiley.com/10.1111/1756-185X.13403
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http://dx.doi.org/10.1111/1756-185X.13403DOI Listing
March 2019
9 Reads
1.771 Impact Factor

Probiotics do have a role to play in treating critically ill children.

Acta Paediatr 2019 01 13;108(1):180. Epub 2018 Aug 13.

Department of Paediatrics, Advanced Paediatric Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

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http://dx.doi.org/10.1111/apa.14510DOI Listing
January 2019
15 Reads
1.842 Impact Factor

Subdural empyema due to Salmonella paratyphi B in an infant: a case report and review of literature.

Childs Nerv Syst 2018 11 10;34(11):2317-2320. Epub 2018 May 10.

Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatrics Centre, PGIMER, Chandigarh, 160012, India.

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http://dx.doi.org/10.1007/s00381-018-3825-7DOI Listing
November 2018
16 Reads
1.163 Impact Factor

Airway pressure release ventilation in acute respiratory distress syndrome: children are not miniature adults.

Intensive Care Med 2018 09 6;44(9):1595-1596. Epub 2018 Aug 6.

Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, 610041, China.

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http://dx.doi.org/10.1007/s00134-018-5337-zDOI Listing
September 2018
7 Reads
7.214 Impact Factor

Varicocele with an Abdominal Mass.

J Pediatr 2018 07 23;198:317-317.e1. Epub 2018 Mar 23.

Division of Pediatric Hematology Oncology Post Graduate Institute of Medical Education and Research Chandigarh, India.

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http://dx.doi.org/10.1016/j.jpeds.2018.02.023DOI Listing
July 2018
9 Reads
3.790 Impact Factor

Muehrcke Lines in an Infant.

J Pediatr 2017 10 5;189:234. Epub 2017 Jun 5.

Division of Pediatrics Post Graduate Institute of Medical Education and Research Chandigarh, India.

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http://dx.doi.org/10.1016/j.jpeds.2017.05.039DOI Listing
October 2017
19 Reads
3.790 Impact Factor

Top co-authors

Muralidharan Jayashree
Muralidharan Jayashree

Postgraduate Institute of Medical Education and Research

12
Karthi Nallasamy
Karthi Nallasamy

Postgraduate Institute of Medical Education and Research

7
Arun Bansal
Arun Bansal

Advanced Pediatrics Center

4
Suresh Kumar Angurana
Suresh Kumar Angurana

Postgraduate Institute of Medical Education and Research

4
Amit Rawat
Amit Rawat

Postgraduate Institute of Medical Education and Research

3
Biraj Parajuli
Biraj Parajuli

Post Graduate Institute of Medical Education and Research

2
Pratibha Singhi
Pratibha Singhi

Postgraduate Institute of Medical Education and Research

2
Pandiarajan Vignesh
Pandiarajan Vignesh

Postgraduate Institute of Medical Education and Research

2