Vienna Ludovini

*Center of Predictive Molecular Medicine, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; †Medical Scientific Affairs Department, Roche Molecular Systems, Pleasanton, California; ‡Oncological and Cardiovascular Molecular Medicine Unit, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; §Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; ‖Department of Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy; ¶Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL of Bologna, Bologna, Italy; #Unit of Pneumology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; **Ospedale Civile di Pescara, Pescara, Italy; ††Ospedale Civile di Sulmona, Sulmona, Italy; ‡‡Department of Medical Oncology, Consorzio Interuniversitario Nazionale per la Bio-Oncologia, G. d'Annunzio University, Chieti, Italy; §§Department of Oncology-Haematology, Humanitas Cancer Center, IRCCS, Milan, Italy; and ‖‖Perugia University Medical School, Perugia, Italy.

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October 2015

Enteric-type adenocarcinoma of the lung harbouring a novel KRAS Q22K mutation with concomitant KRAS polysomy: a case report.

Authors:

Giulio Metro Emanuele Valtorta Annamaria Siggillino Calogero Lauricella Matteo Cenci Vienna Ludovini Elisa Minenza Enrico Prosperi Biagio Ricciuti Alberto Rebonato Alessandra Bassetti Lucio Crinò

Ecancermedicalscience 2015 28;9:559. Epub 2015 Jul 28.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia 06156, Italy.

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August 2015

CSF Concentration of Crizotinib in Two ALK-Positive Non-Small-Cell Lung Cancer Patients with CNS Metastases Deriving Clinical Benefit from Treatment.

Authors:

Giulio Metro Gianluigi Lunardi Piero Floridi Jennifer P Pascali Luca Marcomigni Rita Chiari Vienna Ludovini Lucio Crinò Stefania Gori

J Thorac Oncol 2015 May;10(5):e26-e27

Medical Oncology, Sacro Cuore-Don Calabria Hospital, Negrar, VR, Italy.

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May 2015

MYC and human telomerase gene (TERC) copy number gain in early-stage non-small cell lung cancer.

Authors:

Antonella Flacco Vienna Ludovini Fortunato Bianconi Mark Ragusa Guido Bellezza Francesca R Tofanetti Lorenza Pistola Annamaria Siggillino Jacopo Vannucci Lucio Cagini Angelo Sidoni Francesco Puma Marileila Varella-Garcia Lucio Crinò

Am J Clin Oncol 2015 Apr;38(2):152-8

*Department of Medical Oncology, S. Maria della Misericordia Hospital Departments of †Electronic and Information Engineering ‡Thoracic Surgery §Institute of Pathological Anatomy and Histology, University of Perugia, Perugia, Italy ∥Department of Medicine/Medical Oncology, University of Colorado Cancer Center, Aurora, CO.

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April 2015

Unique case of sporadic multiple gastro intestinal stromal tumour.

Authors:

Luigina Graziosi Elisabetta Marino Vienna Ludovini Alberto Rebonato Verena De Angelis Annibale Donini

Int J Surg Case Rep 2015 15;9:98-100. Epub 2015 Jan 15.

General and Emergency Surgery, Santa Maria della Misericordia Hospital, University of Perugia, Via dottori, 06134 Perugia, Italy.

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April 2015

Impact of upfront cellular enrichment by laser capture microdissection on protein and phosphoprotein drug target signaling activation measurements in human lung cancer: Implications for personalized medicine.

Authors:

Elisa Baldelli Eric B Haura Lucio Crinò Douglas W Cress Vienna Ludovini Matthew B Schabath Lance A Liotta Emanuel F Petricoin Mariaelena Pierobon

Proteomics Clin Appl 2015 Oct 24;9(9-10):928-37. Epub 2015 Mar 24.

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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October 2015

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer.

Oncotarget 2014 Nov;5(22):11054-63

Laboratory of Immunology, Regina Elena National Cancer Institute, Rome, Italy.

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November 2014

MicroRNA signature in metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies.

Authors:

Federico Cappuzzo Andrea Sacconi Lorenza Landi Vienna Ludovini Francesca Biagioni Armida D'Incecco Alessandra Capodanno Jessica Salvini Enrichetta Corgna Samanta Cupini Cecilia Barbara Gabriella Fontanini Lucio Crinò Giovanni Blandino

Clin Colorectal Cancer 2014 Mar 14;13(1):37-45.e4. Epub 2013 Nov 14.

Translational Oncogenomic Unit, National Cancer Institute Regina Elena, Rome, Italy.

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March 2014

Long-term response to gefitinib and crizotinib in lung adenocarcinoma harboring both epidermal growth factor receptor mutation and EML4-ALK fusion gene.

Authors:

Rita Chiari Simona Duranti Vienna Ludovini Guido Bellezza Anjuta Pireddu Vincenzo Minotti Chiara Bennati Lucio Crinò

J Clin Oncol 2014 Mar 13;32(9):e30-2. Epub 2014 Jan 13.

Santa Maria della Misericordia Hospital, Perugia, Italy.

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March 2014

Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status.

Authors:

Giulio Metro Rita Chiari Chiara Bennati Matteo Cenci Biagio Ricciuti Francesco Puma Antonella Flacco Alberto Rebonato Diana Giannarelli Vienna Ludovini Guido Bellezza Piero Ferolla Vincenzo Minotti Lucio Crinò

Clin Lung Cancer 2014 Jan 17;15(1):86-92. Epub 2013 Oct 17.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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January 2014

Co-expression of receptors of the HER family correlates with clinical outcome in non-small cell lung cancer (NSCLC).

Authors:

Guido Bellezza Rachele Del Sordo Renato Colella Vienna Ludovini Mark Ragusa Fortunato Bianconi Ivana Ferri Filippo Borri Rita Chiari Francesco Puma Lucio Crinò Angelo Sidoni

Virchows Arch 2013 Nov 7;463(5):663-71. Epub 2013 Sep 7.

Institute of Pathological Anatomy and Histology, Perugia University, Perugia, Italy,

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November 2013

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcome in resected non-small cell lung cancer patients.

Authors:

Mark Ragusa Jacopo Vannucci Vienna Ludovini Fortunato Bianconi Stefano Treggiari Francesca R Tofanetti Antonella Flacco Renato Colella Angelo Sidoni Lucio Crinò Francesco Puma

Am J Clin Oncol 2014 Aug;37(4):343-9

*Thoracic Surgery Unit ∥Institute of Pathological Anatomy and Histology, University of Perugia Medical School †Medical Oncology Division, S. Maria della Misericordia Hospital ‡Department of Electronic and Information Engineering, University of Perugia, Perugia §Thoracic Surgery Unit, S. Camillo Forlanini Hospital, Roma, Italy.

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August 2014

DKC1 gene mutations in human sporadic cancer.

Authors:

Marianna Penzo Lucia Casoli Claudio Ceccarelli Davide Treré Vienna Ludovini Lucio Crinò Lorenzo Montanaro

Histol Histopathol 2013 03;28(3):365-72

Department of Experimental Pathology, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

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March 2013

Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype.

Authors:

Giulio Metro Rita Chiari Simona Duranti Annamaria Siggillino Matthias J Fischer Diana Giannarelli Vienna Ludovini Chiara Bennati Luca Marcomigni Alice Baldi Michele Giansanti Vincenzo Minotti Lucio Crinò

Lung Cancer 2012 Oct 4;78(1):81-6. Epub 2012 Jul 4.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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October 2012

Association of cytidine deaminase and xeroderma pigmentosum group D polymorphisms with response, toxicity, and survival in cisplatin/gemcitabine-treated advanced non-small cell lung cancer patients.

Authors:

Vienna Ludovini Irene Floriani Lorenza Pistola Vincenzo Minotti Marialuisa Meacci Rita Chiari Daniela Garavaglia Francesca Romana Tofanetti Antonella Flacco Annamaria Siggillino Elisa Baldelli Maurizio Tonato Lucio Crinò

J Thorac Oncol 2011 Dec;6(12):2018-26

Medical Oncology Department, S. Maria della Misericordia Hospital, Perugia, Italy.

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December 2011

Computational model of EGFR and IGF1R pathways in lung cancer: a Systems Biology approach for Translational Oncology.

Authors:

Fortunato Bianconi Elisa Baldelli Vienna Ludovini Lucio Crinò Antonella Flacco Paolo Valigi

Biotechnol Adv 2012 Jan-Feb;30(1):142-53. Epub 2011 May 18.

Department of Electronic and Information Engineering, Perugia University, Italy.

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July 2012

Phosphoinositide-3-kinase catalytic alpha and KRAS mutations are important predictors of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer.

Authors:

Vienna Ludovini Fortunato Bianconi Lorenza Pistola Rita Chiari Vincenzo Minotti Renato Colella Dario Giuffrida Francesca Romana Tofanetti Annamaria Siggillino Antonella Flacco Elisa Baldelli Daniela Iacono Maria Grazia Mameli Antonio Cavaliere Lucio Crinò

J Thorac Oncol 2011 Apr;6(4):707-15

Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy.

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April 2011

CYP17, GSTP1, PON1 and GLO1 gene polymorphisms as risk factors for breast cancer: an Italian case-control study.

Authors:

Cinzia Antognelli Chiara Del Buono Vienna Ludovini Stefania Gori Vincenzo N Talesa Lucio Crinò Francesco Barberini Antonio Rulli

BMC Cancer 2009 Apr 20;9:115. Epub 2009 Apr 20.

Department of Experimental Medicine, University of Perugia, Perugia, Italy.

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April 2009

Biological markers and DNA flow cytometric analysis in radically resected patients with non-small cell lung cancer. A study of the Perugia Multidisciplinary Team for Thoracic Tumors.

Authors:

Vienna Ludovini Lorenza Pistola Vanesa Gregorc Irene Floriani Eliana Rulli Luciana Di Carlo Antonia Semeraro Giuliano Daddi Samir Darwish Lucia Stocchi Francesca Romana Tofanetti Guido Bellezza Angelo Sidoni Rita Tognellini Lucio Crinò Maurizio Tonato

Tumori 2008 May-Jun;94(3):398-405

Medical Oncology, Azienda Ospedaliera, Perugia, Italy.

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August 2008

Long-lasting complete remission with tyrosine kinase inhibitor in bronchioloalveolar carcinoma with a so far unknown EGFR mutation.

Authors:

Vienna Ludovini Stefania Gori Lorenza Pistola Maria Agnese Della Fazia Danilo Piobbico Giuseppe Servillo Antonella Flacco Cristina Scuderi Lucio Crinò

J Thorac Oncol 2008 Apr;3(4):452-3

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April 2008

Plasma DNA, microsatellite alterations, and p53 tumor mutations are associated with disease-free survival in radically resected non-small cell lung cancer patients: a study of the perugia multidisciplinary team for thoracic oncology.

Authors:

Vienna Ludovini Lorenza Pistola Vanesa Gregorc Irene Floriani Eliana Rulli Simonetta Piattoni Luciana Di Carlo Antonia Semeraro Samir Darwish Francesca Romana Tofanetti Lucia Stocchi Zhasmina Mihaylova Guido Bellezza Rachele Del Sordo Giuliano Daddi Lucio Crinò Maurizio Tonato

J Thorac Oncol 2008 Apr;3(4):365-73

Medical Oncology Division, Azienda Ospedale Perugia, Via Brunamonti 51, 06122 Perugia, Italy.

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April 2008

Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties.

Authors:

Andrea Prodosmo Simona Giglio Sonia Moretti Francesca Mancini Flavia Barbi Nicola Avenia Giusy Di Conza Holger J Schünemann Lorenza Pistola Vienna Ludovini Ada Sacchi Alfredo Pontecorvi Efisio Puxeddu Fabiola Moretti

J Mol Med (Berl) 2008 May 12;86(5):585-96. Epub 2008 Mar 12.

Lab. Molecular Oncogenesis, Regina Elena Cancer Institute, Rome, Italy.

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May 2008

Prognostic value of circulating chromogranin A and soluble tumor necrosis factor receptors in advanced nonsmall cell lung cancer.

Authors:

Vanesa Gregorc Anna Spreafico Irene Floriani Barbara Colombo Vienna Ludovini Lorenza Pistola Guido Bellezza Maria Grazia Viganò Eugenio Villa Angelo Corti

Cancer 2007 Aug;110(4):845-53

Department of Oncology, San Raffaele Scientific Institute, Milan, Italy.

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August 2007

Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort cross-institutional study.

J Natl Cancer Inst 2007 Jun;99(11):838-46

Department of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, TN 37232-6838, USA.

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June 2007

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib.

Authors:

George Cusatis Vanesa Gregorc Jing Li Anna Spreafico Roxann G Ingersoll Jaap Verweij Vienna Ludovini Eugenio Villa Manuel Hidalgo Alex Sparreboom Sharyn D Baker

J Natl Cancer Inst 2006 Dec;98(23):1739-42

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.

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December 2006

Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients.

Authors:

Federico Cappuzzo Marileila Varella-Garcia Hisayuki Shigematsu Irene Domenichini Stefania Bartolini Giovanni L Ceresoli Elisa Rossi Vienna Ludovini Vanesa Gregorc Luca Toschi Wilbur A Franklin Lucio Crino Adi F Gazdar Paul A Bunn Fred R Hirsch

J Clin Oncol 2005 Aug;23(22):5007-18

University of Colorado Cancer Center, Department of Medicine and Pathology, Aurora, CO 80010, USA.

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August 2005

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer.

J Natl Cancer Inst 2005 May;97(9):643-55

University of Colorado Health Sciences Center and University of Colorado Cancer Center, Aurora, CO 80010, USA.

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May 2005

Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer.

Authors:

Vanesa Gregorc Giovanni Luca Ceresoli Irene Floriani Anna Spreafico Katia Bruna Bencardino Vienna Ludovini Lorenza Pistola Zhasmina Mihaylova Francesca Romana Tofanetti Massimiliano Ferraldeschi Valter Torri Federico Cappuzzo Lucio Crinò Maurizio Tonato Eugenio Villa

Clin Cancer Res 2004 Sep;10(18 Pt 1):6006-12

Department of Oncology, Scientific Institute University Hospital San Raffaele, Milan.

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September 2004

Vascular endothelial growth factor, p53, Rb, Bcl-2 expression and response to chemotherapy in advanced non-small cell lung cancer.

Authors:

Vienna Ludovini Vanesa Gregorc Lorenza Pistola Zhasmina Mihaylova Irene Floriani Samir Darwish Fabrizio Stracci Francesca Romana Tofanetti Massimiliano Ferraldeschi Luciana Di Carlo Mark Ragusa Giuliano Daddi Maurizio Tonato

Lung Cancer 2004 Oct;46(1):77-85

Division of Medical Oncology, Policlinico Monteluce Hospital, Via Brunamonti 51, 06122 Perugia, Italy.

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October 2004

Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer.

Authors:

Federico Cappuzzo Elisabetta Magrini Giovanni Luca Ceresoli Stefania Bartolini Elisa Rossi Vienna Ludovini Vanesa Gregorc Claudia Ligorio Alessandra Cancellieri Stefania Damiani Anna Spreafico Carlo Terenzio Paties Laura Lombardo Cesare Calandri Guido Bellezza Maurizio Tonato Lucio Crinò

J Natl Cancer Inst 2004 Aug;96(15):1133-41

Department of Oncologic Sciences, Bellaria-Maggiore Hospital, Bologna, Italy.

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August 2004

The clinical relevance of Bcl-2, Rb and p53 expression in advanced non-small cell lung cancer.

Authors:

Vanesa Gregorc Samir Darwish Vienna Ludovini Lorenza Pistola Verena De Angelis Zhasmina Mihaylova Guido Bellezza Angelo Sidoni Antonio Cavaliere Emilio Bucciarelli Giovanni Massaro Maurizio Tonato

Lung Cancer 2003 Dec;42(3):275-81

Division of Medical Oncology, Policlinico Monteluce, Via Brunamonti 51, Perugia 06122, Italy.

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December 2003

Relevance of p53, bcl-2 and Rb expression on resistance to cisplatin-based chemotherapy in advanced non-small cell lung cancer.

Authors:

Vanesa Gregorc Vienna Ludovini Lorenza Pistola Samir Darwish Irene Floriani Guido Bellezza Angelo Sidoni Antonio Cavaliere Massimo Scheibel Verena De Angelis Emilio Bucciarelli Maurizio Tonato

Lung Cancer 2003 Jan;39(1):41-8

Division of Medical Oncology, Policlinico Monteluce, Perugia, Italy.

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January 2003

Publications by authors named "Vienna Ludovini"

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