Victoria B Risbrough

Victoria B Risbrough

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Victoria B Risbrough

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Angiotensin II Signaling and Fear Extinction: Translational Evidence and Novel Receptor Targets.

Biol Psychiatry 2019 Dec;86(12):874-876

Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, San Diego, California; Department of Psychiatry, University of California San Diego, San Diego, California. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.09.026DOI Listing
December 2019

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Authors:
Caroline M Nievergelt Adam X Maihofer Torsten Klengel Elizabeth G Atkinson Chia-Yen Chen Karmel W Choi Jonathan R I Coleman Shareefa Dalvie Laramie E Duncan Joel Gelernter Daniel F Levey Mark W Logue Renato Polimanti Allison C Provost Andrew Ratanatharathorn Murray B Stein Katy Torres Allison E Aiello Lynn M Almli Ananda B Amstadter Søren B Andersen Ole A Andreassen Paul A Arbisi Allison E Ashley-Koch S Bryn Austin Esmina Avdibegovic Dragan Babić Marie Bækvad-Hansen Dewleen G Baker Jean C Beckham Laura J Bierut Jonathan I Bisson Marco P Boks Elizabeth A Bolger Anders D Børglum Bekh Bradley Megan Brashear Gerome Breen Richard A Bryant Angela C Bustamante Jonas Bybjerg-Grauholm Joseph R Calabrese José M Caldas-de-Almeida Anders M Dale Mark J Daly Nikolaos P Daskalakis Jürgen Deckert Douglas L Delahanty Michelle F Dennis Seth G Disner Katharina Domschke Alma Dzubur-Kulenovic Christopher R Erbes Alexandra Evans Lindsay A Farrer Norah C Feeny Janine D Flory David Forbes Carol E Franz Sandro Galea Melanie E Garrett Bizu Gelaye Elbert Geuze Charles Gillespie Aferdita Goci Uka Scott D Gordon Guia Guffanti Rasha Hammamieh Supriya Harnal Michael A Hauser Andrew C Heath Sian M J Hemmings David Michael Hougaard Miro Jakovljevic Marti Jett Eric Otto Johnson Ian Jones Tanja Jovanovic Xue-Jun Qin Angela G Junglen Karen-Inge Karstoft Milissa L Kaufman Ronald C Kessler Alaptagin Khan Nathan A Kimbrel Anthony P King Nastassja Koen Henry R Kranzler William S Kremen Bruce R Lawford Lauren A M Lebois Catrin E Lewis Sarah D Linnstaedt Adriana Lori Bozo Lugonja Jurjen J Luykx Michael J Lyons Jessica Maples-Keller Charles Marmar Alicia R Martin Nicholas G Martin Douglas Maurer Matig R Mavissakalian Alexander McFarlane Regina E McGlinchey Katie A McLaughlin Samuel A McLean Sarah McLeay Divya Mehta William P Milberg Mark W Miller Rajendra A Morey Charles Phillip Morris Ole Mors Preben B Mortensen Benjamin M Neale Elliot C Nelson Merete Nordentoft Sonya B Norman Meaghan O'Donnell Holly K Orcutt Matthew S Panizzon Edward S Peters Alan L Peterson Matthew Peverill Robert H Pietrzak Melissa A Polusny John P Rice Stephan Ripke Victoria B Risbrough Andrea L Roberts Alex O Rothbaum Barbara O Rothbaum Peter Roy-Byrne Ken Ruggiero Ariane Rung Bart P F Rutten Nancy L Saccone Sixto E Sanchez Dick Schijven Soraya Seedat Antonia V Seligowski Julia S Seng Christina M Sheerin Derrick Silove Alicia K Smith Jordan W Smoller Scott R Sponheim Dan J Stein Jennifer S Stevens Jennifer A Sumner Martin H Teicher Wesley K Thompson Edward Trapido Monica Uddin Robert J Ursano Leigh Luella van den Heuvel Miranda Van Hooff Eric Vermetten Christiaan H Vinkers Joanne Voisey Yunpeng Wang Zhewu Wang Thomas Werge Michelle A Williams Douglas E Williamson Sherry Winternitz Christiane Wolf Erika J Wolf Jonathan D Wolff Rachel Yehuda Ross McD Young Keith A Young Hongyu Zhao Lori A Zoellner Israel Liberzon Kerry J Ressler Magali Haas Karestan C Koenen

Nat Commun 2019 Oct 8;10(1):4558. Epub 2019 Oct 8.

Broad Institute of MIT and Harvard, Stanley Center for Psychiatric Research, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41467-019-12576-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783435PMC
October 2019

Sleep disturbance at pre-deployment is a significant predictor of post-deployment re-experiencing symptoms.

Eur J Psychotraumatol 2019 29;10(1):1679964. Epub 2019 Oct 29.

Center for Excellence in Stress and Mental Health, VA San Diego Healthcare System, San Diego, CA, USA.

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http://dx.doi.org/10.1080/20008198.2019.1679964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830277PMC
October 2019

Common pathways and communication between the brain and heart: connecting post-traumatic stress disorder and heart failure.

Stress 2019 Sep 4;22(5):530-547. Epub 2019 Jun 4.

h Department of Cell Biology and Anatomy, University of South Carolina School of Medicine and Research Service, Columbia VA Health Care System , Columbia , SC , USA.

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https://www.tandfonline.com/doi/full/10.1080/10253890.2019.1
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http://dx.doi.org/10.1080/10253890.2019.1621283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690762PMC
September 2019

Characterizing the neural circuitry associated with configural threat learning.

Brain Res 2019 Sep 4;1719:225-234. Epub 2019 Jun 4.

Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, CA 92161, USA; Department of Psychiatry, University of California San Diego, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1016/j.brainres.2019.06.003DOI Listing
September 2019

Sleep Disruption, Safety Learning, and Fear Extinction in Humans: Implications for Posttraumatic Stress Disorder.

Curr Top Behav Neurosci 2018;38:193-205

Research Service, VA San Diego Healthcare System, San Diego, CA, USA.

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http://dx.doi.org/10.1007/7854_2017_31DOI Listing
May 2019

The Future of Contextual Fear Learning for PTSD Research: A Methodological Review of Neuroimaging Studies.

Curr Top Behav Neurosci 2018;38:207-228

Center of Excellence for Stress and Mental Health, Veterans Affairs San Diego Healthcare System, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1007/7854_2017_30DOI Listing
May 2019

REM sleep and safety signal learning in posttraumatic stress disorder: A preliminary study in military veterans.

Neurobiol Stress 2018 Nov 20;9:22-28. Epub 2018 Jul 20.

Monash Institute for Cognitive and Clinical Neuroscience, School of Psychological Sciences, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1016/j.ynstr.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084022PMC
November 2018

Heritable Differences in Catecholamine Signaling Modulate Susceptibility to Trauma and Response to Methylphenidate Treatment: Relevance for PTSD.

Front Behav Neurosci 2019 17;13:111. Epub 2019 May 17.

Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fnbeh.2019.00111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534065PMC
May 2019

Measuring novel antecedents of mental illness: the Questionnaire of Unpredictability in Childhood.

Neuropsychopharmacology 2019 04 23;44(5):876-882. Epub 2018 Nov 23.

Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA.

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http://dx.doi.org/10.1038/s41386-018-0280-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461958PMC
April 2019

Impact of TBI, PTSD, and Hearing Loss on Tinnitus Progression in a US Marine Cohort.

Mil Med 2019 Feb 22. Epub 2019 Feb 22.

VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA.

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https://academic.oup.com/milmed/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/milmed/usz016DOI Listing
February 2019

Aversive distractors modulate affective working memory in frontoparietal regions.

Emotion 2018 Dec 20. Epub 2018 Dec 20.

Center of Excellence for Stress and Mental Health.

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http://dx.doi.org/10.1037/emo0000544DOI Listing
December 2018

REM sleep and safety signal learning in posttraumatic stress disorder: A preliminary study in military veterans.

Neurobiol Stress 2018 Nov 20;9:22-28. Epub 2018 Jul 20.

Monash Institute for Cognitive and Clinical Neuroscience, School of Psychological Sciences, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1016/j.ynstr.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084022PMC
November 2018

A signal detection-item response theory model for evaluating neuropsychological measures.

J Clin Exp Neuropsychol 2018 10 5;40(8):745-760. Epub 2018 Feb 5.

a Department of Psychiatry , University of California San Diego , La Jolla , CA , USA.

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http://dx.doi.org/10.1080/13803395.2018.1427699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050112PMC
October 2018

Current Status of Animal Models of Posttraumatic Stress Disorder: Behavioral and Biological Phenotypes, and Future Challenges in Improving Translation.

Biol Psychiatry 2018 05 20;83(10):895-907. Epub 2017 Nov 20.

Department of Psychiatry, University of California San Diego, La Jolla, California; Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085893PMC
May 2018

Neural measures associated with configural threat acquisition.

Neurobiol Learn Mem 2018 04 12;150:99-106. Epub 2018 Mar 12.

Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, CA 92161, USA; Department of Psychiatry, University of California San Diego, San Diego, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nlm.2018.03.012DOI Listing
April 2018

Individual variation in working memory is associated with fear extinction performance.

Behav Res Ther 2018 03 5;102:52-59. Epub 2018 Jan 5.

Research Service, VA San Diego Healthcare system, San Diego, CA 92161, USA.

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http://dx.doi.org/10.1016/j.brat.2018.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182776PMC
March 2018

PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma.

Neuropsychopharmacology 2018 02 19;43(3):469-481. Epub 2017 Sep 19.

Departments of Psychiatry and Behavioral Sciences & Neuroscience and Physiology, Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), SUNY Upstate Medical University, Syracuse, NY, USA.

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http://dx.doi.org/10.1038/npp.2017.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770765PMC
February 2018

Effects of military service and deployment on clinical symptomatology: The role of trauma exposure and social support.

J Psychiatr Res 2017 12 19;95:121-128. Epub 2017 Aug 19.

Department of Psychiatry, Brain Behavior Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; VISN4 Mental Illness Research, Education, and Clinical Center at the Philadelphia VA Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2017.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653464PMC
December 2017

Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms.

Depress Anxiety 2017 08 10;34(8):723-733. Epub 2017 May 10.

Center of Excellence for Stress and Mental Health, San Diego Veterans Affairs Health Services, CA, USA.

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http://dx.doi.org/10.1002/da.22642DOI Listing
August 2017

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Authors:
Ilja M Nolte M Loretto Munoz Vinicius Tragante Azmeraw T Amare Rick Jansen Ahmad Vaez Benedikt von der Heyde Christy L Avery Joshua C Bis Bram Dierckx Jenny van Dongen Stephanie M Gogarten Philippe Goyette Jussi Hernesniemi Ville Huikari Shih-Jen Hwang Deepali Jaju Kathleen F Kerr Alexander Kluttig Bouwe P Krijthe Jitender Kumar Sander W van der Laan Leo-Pekka Lyytikäinen Adam X Maihofer Arpi Minassian Peter J van der Most Martina Müller-Nurasyid Michel Nivard Erika Salvi James D Stewart Julian F Thayer Niek Verweij Andrew Wong Delilah Zabaneh Mohammad H Zafarmand Abdel Abdellaoui Sulayma Albarwani Christine Albert Alvaro Alonso Foram Ashar Juha Auvinen Tomas Axelsson Dewleen G Baker Paul I W de Bakker Matteo Barcella Riad Bayoumi Rob J Bieringa Dorret Boomsma Gabrielle Boucher Annie R Britton Ingrid Christophersen Andrea Dietrich George B Ehret Patrick T Ellinor Markku Eskola Janine F Felix John S Floras Oscar H Franco Peter Friberg Maaike G J Gademan Mark A Geyer Vilmantas Giedraitis Catharina A Hartman Daiane Hemerich Albert Hofman Jouke-Jan Hottenga Heikki Huikuri Nina Hutri-Kähönen Xavier Jouven Juhani Junttila Markus Juonala Antti M Kiviniemi Jan A Kors Meena Kumari Tatiana Kuznetsova Cathy C Laurie Joop D Lefrandt Yong Li Yun Li Duanping Liao Marian C Limacher Henry J Lin Cecilia M Lindgren Steven A Lubitz Anubha Mahajan Barbara McKnight Henriette Meyer Zu Schwabedissen Yuri Milaneschi Nina Mononen Andrew P Morris Mike A Nalls Gerjan Navis Melanie Neijts Kjell Nikus Kari E North Daniel T O'Connor Johan Ormel Siegfried Perz Annette Peters Bruce M Psaty Olli T Raitakari Victoria B Risbrough Moritz F Sinner David Siscovick Johannes H Smit Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Jan A Staessen Phyllis K Stein Adrienne M Stilp Katarzyna Stolarz-Skrzypek Konstantin Strauch Johan Sundström Cees A Swenne Ann-Christine Syvänen Jean-Claude Tardif Kent D Taylor Alexander Teumer Timothy A Thornton Lesley E Tinker André G Uitterlinden Jessica van Setten Andreas Voss Melanie Waldenberger Kirk C Wilhelmsen Gonneke Willemsen Quenna Wong Zhu-Ming Zhang Alan B Zonderman Daniele Cusi Michele K Evans Halina K Greiser Pim van der Harst Mohammad Hassan Erik Ingelsson Marjo-Riitta Järvelin Stefan Kääb Mika Kähönen Mika Kivimaki Charles Kooperberg Diana Kuh Terho Lehtimäki Lars Lind Caroline M Nievergelt Chris J O'Donnell Albertine J Oldehinkel Brenda Penninx Alexander P Reiner Harriëtte Riese Arie M van Roon John D Rioux Jerome I Rotter Tamar Sofer Bruno H Stricker Henning Tiemeier Tanja G M Vrijkotte Folkert W Asselbergs Bianca J J M Brundel Susan R Heckbert Eric A Whitsel Marcel den Hoed Harold Snieder Eco J C de Geus

Nat Commun 2017 08 2;8:16140. Epub 2017 Aug 2.

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http://dx.doi.org/10.1038/ncomms16140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543301PMC
August 2017

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Authors:
Ilja M Nolte M Loretto Munoz Vinicius Tragante Azmeraw T Amare Rick Jansen Ahmad Vaez Benedikt von der Heyde Christy L Avery Joshua C Bis Bram Dierckx Jenny van Dongen Stephanie M Gogarten Philippe Goyette Jussi Hernesniemi Ville Huikari Shih-Jen Hwang Deepali Jaju Kathleen F Kerr Alexander Kluttig Bouwe P Krijthe Jitender Kumar Sander W van der Laan Leo-Pekka Lyytikäinen Adam X Maihofer Arpi Minassian Peter J van der Most Martina Müller-Nurasyid Michel Nivard Erika Salvi James D Stewart Julian F Thayer Niek Verweij Andrew Wong Delilah Zabaneh Mohammad H Zafarmand Abdel Abdellaoui Sulayma Albarwani Christine Albert Alvaro Alonso Foram Ashar Juha Auvinen Tomas Axelsson Dewleen G Baker Paul I W de Bakker Matteo Barcella Riad Bayoumi Rob J Bieringa Dorret Boomsma Gabrielle Boucher Annie R Britton Ingrid Christophersen Andrea Dietrich George B Ehret Patrick T Ellinor Markku Eskola Janine F Felix John S Floras Oscar H Franco Peter Friberg Maaike G J Gademan Mark A Geyer Vilmantas Giedraitis Catharina A Hartman Daiane Hemerich Albert Hofman Jouke-Jan Hottenga Heikki Huikuri Nina Hutri-Kähönen Xavier Jouven Juhani Junttila Markus Juonala Antti M Kiviniemi Jan A Kors Meena Kumari Tatiana Kuznetsova Cathy C Laurie Joop D Lefrandt Yong Li Yun Li Duanping Liao Marian C Limacher Henry J Lin Cecilia M Lindgren Steven A Lubitz Anubha Mahajan Barbara McKnight Henriette Meyer Zu Schwabedissen Yuri Milaneschi Nina Mononen Andrew P Morris Mike A Nalls Gerjan Navis Melanie Neijts Kjell Nikus Kari E North Daniel T O'Connor Johan Ormel Siegfried Perz Annette Peters Bruce M Psaty Olli T Raitakari Victoria B Risbrough Moritz F Sinner David Siscovick Johannes H Smit Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Jan A Staessen Phyllis K Stein Adrienne M Stilp Katarzyna Stolarz-Skrzypek Konstantin Strauch Johan Sundström Cees A Swenne Ann-Christine Syvänen Jean-Claude Tardif Kent D Taylor Alexander Teumer Timothy A Thornton Lesley E Tinker André G Uitterlinden Jessica van Setten Andreas Voss Melanie Waldenberger Kirk C Wilhelmsen Gonneke Willemsen Quenna Wong Zhu-Ming Zhang Alan B Zonderman Daniele Cusi Michele K Evans Halina K Greiser Pim van der Harst Mohammad Hassan Erik Ingelsson Marjo-Riitta Järvelin Stefan Kääb Mika Kähönen Mika Kivimaki Charles Kooperberg Diana Kuh Terho Lehtimäki Lars Lind Caroline M Nievergelt Chris J O'Donnell Albertine J Oldehinkel Brenda Penninx Alexander P Reiner Harriëtte Riese Arie M van Roon John D Rioux Jerome I Rotter Tamar Sofer Bruno H Stricker Henning Tiemeier Tanja G M Vrijkotte Folkert W Asselbergs Bianca J J M Brundel Susan R Heckbert Eric A Whitsel Marcel den Hoed Harold Snieder Eco J C de Geus

Nat Commun 2017 06 14;8:15805. Epub 2017 Jun 14.

Department of Biological Psychology, Behavioral and Movement Sciences, VU University, Amsterdam 1081 BT, The Netherlands.

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http://dx.doi.org/10.1038/ncomms15805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474732PMC
June 2017

Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice.

Behav Brain Res 2017 04 31;323:117-123. Epub 2017 Jan 31.

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA; Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.01.048DOI Listing
April 2017

Immune signaling mechanisms of PTSD risk and symptom development: insights from animal models.

Curr Opin Behav Sci 2017 Apr;14:123-132

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.cobeha.2017.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525319PMC
April 2017

Sleep Deprivation Disrupts Recall of Conditioned Fear Extinction.

Biol Psychiatry Cogn Neurosci Neuroimaging 2017 Mar;2(2):123-129

Monash Institute of Cognitive and Clinical Neurosciences. Clayton, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.bpsc.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526630PMC
March 2017

On the Road to Translation for PTSD Treatment: Theoretical and Practical Considerations of the Use of Human Models of Conditioned Fear for Drug Development.

Curr Top Behav Neurosci 2016;28:173-96

Center of Excellence for Stress and Mental Health, San Diego, VA, USA.

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http://dx.doi.org/10.1007/7854_2015_5010DOI Listing
December 2016

Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females.

Neuropsychopharmacology 2016 12;41(13):2963-2964

Department of Psychiatry, Columbia University, College of Physicians & Surgeons, New York, NY, USA.

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http://dx.doi.org/10.1038/npp.2015.363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101545PMC
December 2016

Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines.

J Head Trauma Rehabil 2016 Jan-Feb;31(1):30-9

VA San Diego Healthcare System, San Diego, California (Drs Yurgil, Risbrough, Geyer, and Baker); VA Center of Excellence for Stress and Mental Health, San Diego, California (Drs Yurgil, Risbrough, and Baker); Department of Psychological Sciences, Loyola University New Orleans, New Orleans, Louisiana (Dr Yurgil); Naval Medical Center San Diego, San Diego, California (Dr Clifford); Harvard School of Public Health, Boston, Massachusetts (Dr Clifford); Departments of Psychiatry (Drs Risbrough, Geyer, and Baker) and Radiology (Dr Huang), University of California San Diego; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles (Dr Barkauskas); VA Boston Healthcare System, Boston, Massachusetts (Dr Vasterling); VA National Center for PTSD, Boston, Massachusetts (Dr Vasterling); and Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts (Dr Vasterling).

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http://pdfs.journals.lww.com/headtraumarehab/2016/01000/Pros
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/HTR.0000000000000117DOI Listing
October 2016

Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood.

Neuropsychopharmacology 2016 May 5;41(6):1681-90. Epub 2015 Nov 5.

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/npp.2015.338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832031PMC
May 2016

HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES.

Depress Anxiety 2016 Mar 15;33(3):192-202. Epub 2016 Feb 15.

Center of Excellence for Stress and Mental Health, San Diego Veterans Affairs Health Services, San Diego, California.

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http://dx.doi.org/10.1002/da.22475DOI Listing
March 2016

Heart Rate Variability and Posttraumatic Stress Disorder.

JAMA Psychiatry 2016 Feb;73(2):178-9

Center of Excellence for Stress and Mental Health, Veterans Administration, San Diego, California2Department of Psychiatry, University of California-San Diego3Veterans Administration San Diego Healthcare System, San Diego, California.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.2663DOI Listing
February 2016

The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats.

Neuropharmacology 2015 Oct 19;97:357-64. Epub 2015 May 19.

Department of Psychiatry, Health Sciences, University of California San Diego, La Jolla, CA, USA; Veterans Affairs Center of Excellence for Stress and Mental Health, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537349PMC
October 2015

Fear extinction memory performance in a sample of stable, euthymic patients with bipolar disorder.

J Affect Disord 2015 Oct 21;185:230-8. Epub 2015 Jul 21.

Department of Psychiatry, University of California San Diego, USA; Center for Excellence in Stress and Mental Health, USA.

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http://dx.doi.org/10.1016/j.jad.2015.06.053DOI Listing
October 2015

Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines.

JAMA Psychiatry 2015 Oct;72(10):979-86

Center of Excellence for Stress and Mental Health, Veteran's Administration, San Diego, California2Department of Psychiatry, University of California, San Diego, La Jolla, California3Department of Psychiatry, Veterans Administration San Diego Healthcare S.

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http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamapsychiatry.2015.0922DOI Listing
October 2015

Oxytocin enhancement of fear extinction: a new target for facilitating exposure-based treatments?

Biol Psychiatry 2015 Aug;78(3):154-5

Department of Veterans Affairs Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, California. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.06.002DOI Listing
August 2015

Intranasal oxytocin administration prior to exposure therapy for arachnophobia impedes treatment response.

Depress Anxiety 2015 Jun 31;32(6):400-7. Epub 2015 Mar 31.

Department of Psychiatry, University of California, San Diego, La Jolla, San Diego, California.

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http://dx.doi.org/10.1002/da.22362DOI Listing
June 2015

Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice.

Int J Neuropsychopharmacol 2015 Jun 2;18(11):pyv063. Epub 2015 Jun 2.

Department of Psychiatry, University of California San Diego, La Jolla, CA (Ms Higa, Drs Ji, Risbrough, Powell, Young, Geyer, and Zhou, and Ms Buell); Research Service, VA San Diego Healthcare System, La Jolla, CA (Drs Risbrough, Powell, Young, Geyer, and Zhou, and Ms Buell); Neurosciences Graduate Program, University of California San Diego, La Jolla, CA (Ms Higa).

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http://biorxiv.org/content/biorxiv/early/2015/02/26/015677.f
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http://ijnp.oxfordjournals.org/lookup/doi/10.1093/ijnp/pyv06
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http://dx.doi.org/10.1093/ijnp/pyv063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756721PMC
June 2015

Pavlovian conditioning to hedonic food cues in overweight and lean individuals.

Appetite 2015 Apr 16;87:56-61. Epub 2014 Dec 16.

Department of Pediatrics, University of California San Diego, USA; Department of Psychiatry, University of California San Diego, USA. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2014.12.002DOI Listing
April 2015

Voxel-wise resting-state MEG source magnitude imaging study reveals neurocircuitry abnormality in active-duty service members and veterans with PTSD.

Neuroimage Clin 2014 7;5:408-19. Epub 2014 Aug 7.

Radiology, Research, and Psychiatry Services, VA San Diego Healthcare System, San Diego, CA, USA ; VA Center of Excellence for Stress and Mental Health, San Diego, CA, USA ; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1016/j.nicl.2014.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145534PMC
March 2015

Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.

Psychoneuroendocrinology 2015 Jan 30;51:459-71. Epub 2014 Oct 30.

VA Center of Excellence for Stress and Mental Health (CESAMH), VA San Diego Healthcare System, La Jolla, CA 92161, USA; Department of Psychiatry, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.psyneuen.2014.10.017DOI Listing
January 2015

Fear conditioning, safety learning, and sleep in humans.

J Neurosci 2014 Aug;34(35):11754-60

Psychology Services, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, Veterans Affairs San Diego Center for Excellence in Stress and Mental Health, San Diego, California 92161, Department of Psychiatry, University of California San Diego, San Diego, California 92093-0603, and SDSU-UCSD Joint Doctoral Program in Clinical Psychology; San Diego, California 92120

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0478-14.2
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http://dx.doi.org/10.1523/JNEUROSCI.0478-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608408PMC
August 2014

Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry.

Behav Brain Res 2014 Jul 19;267:6-11. Epub 2014 Mar 19.

VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA; Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059187PMC
July 2014

Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice.

Neuropsychopharmacology 2014 May 11;39(6):1409-19. Epub 2013 Dec 11.

1] Department of Psychiatry, University of California San Diego, La Jolla, CA, USA [2] Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/npp.2013.336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988544PMC
May 2014

Inhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating.

Psychopharmacology (Berl) 2014 May 21;231(10):2189-97. Epub 2013 Dec 21.

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA,

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http://dx.doi.org/10.1007/s00213-013-3371-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017785PMC
May 2014

Heart rate variability characteristics in a large group of active-duty marines and relationship to posttraumatic stress.

Psychosom Med 2014 May;76(4):292-301

From the Center of Excellence for Stress and Mental Health (A.M., M.A.G., D.G.B., C.M.N., V.B.R.), Veteran's Administration, San Diego, California; Departments of Psychiatry (A.M., M.A.G., D.G.B., C.M.N., V.B.R.) and Medicine (D.T.O.), University of California San Diego, La Jolla, California; and VA San Diego Healthcare System (M.A.G., D.G.B., C.M.N., V.B.R.), San Diego, California.

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http://dx.doi.org/10.1097/PSY.0000000000000056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062545PMC
May 2014

Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice.

Neuropharmacology 2013 Jul 29;70:156-67. Epub 2013 Jan 29.

Department of Psychiatry, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2013.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644349PMC
July 2013

The effect of pregabalin on sensorimotor gating in 'low' gating humans and mice.

Neuropharmacology 2012 Sep 2;63(3):480-5. Epub 2012 May 2.

Mental Illness Research, Education and Clinical Center-MIRECC, Veterans Affairs VISN22, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2012.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572212PMC
September 2012

Effects of anxiolytic treatment on potentiated startle during aversive image anticipation.

Hum Psychopharmacol 2012 Jul 10;27(4):419-27. Epub 2012 Jul 10.

Mental Illness Research, Education and Clinical Center (MIRECC), Veterans Affairs VISN22, San Diego, California, USA.

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http://dx.doi.org/10.1002/hup.2243DOI Listing
July 2012

Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged mice.

Neurosci Lett 2012 May 6;516(1):161-5. Epub 2012 Apr 6.

Sam and Rose Stein Institute for Research on Aging, Department of Psychiatry, School of Medicine, University of California, San Diego, CA 92093-0603, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338865PMC
May 2012

Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice.

Age (Dordr) 2012 Apr 23;34(2):305-16. Epub 2011 Mar 23.

Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, 92093-0603, USA.

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http://link.springer.com/10.1007/s11357-011-9234-4
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http://dx.doi.org/10.1007/s11357-011-9234-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312638PMC
April 2012

Impaired sensorimotor gating in unmedicated adults with obsessive-compulsive disorder.

Neuropsychopharmacology 2012 Apr 4;37(5):1216-23. Epub 2012 Jan 4.

Department of Psychiatry, Columbia University, College of Physicians & Surgeons, New York, NY 10032-2695-2695, USA.

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http://dx.doi.org/10.1038/npp.2011.308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306882PMC
April 2012

Hippocampal dysfunction effects on context memory: possible etiology for posttraumatic stress disorder.

Neuropharmacology 2012 Feb 11;62(2):674-85. Epub 2011 May 11.

Mental Illness Research, Education and Clinical Center (MIRECC), Veterans Affairs VISN22, CA, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2011.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175276PMC
February 2012

Corticotropin-releasing factor and noradrenergic signalling exert reciprocal control over startle reactivity.

Int J Neuropsychopharmacol 2011 Oct 21;14(9):1179-94. Epub 2010 Dec 21.

Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1017/S1461145710001409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601827PMC
October 2011

Factor analysis of attentional set-shifting performance in young and aged mice.

Behav Brain Funct 2011 Aug 12;7:33. Epub 2011 Aug 12.

Department of Information & Communication Sciences, Sophia University, Tokyo, Japan.

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http://dx.doi.org/10.1186/1744-9081-7-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174878PMC
August 2011

Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice.

Brain Res 2011 Jan 11;1368:65-70. Epub 2010 Nov 11.

Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.brainres.2010.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018762PMC
January 2011

The effects of globin on microarray-based gene expression analysis of mouse blood.

Mamm Genome 2010 Jun 16;21(5-6):268-75. Epub 2010 May 16.

Graduate Program in Biomedical Sciences, Department of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1007/s00335-010-9261-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890980PMC
June 2010

Isolation rearing-induced deficits in contextual fear learning do not require CRF(2) receptors.

Behav Brain Res 2010 May 25;209(1):80-4. Epub 2010 Jan 25.

Department of Psychiatry, University of California, San Diego, MC0804, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1016/j.bbr.2010.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832092PMC
May 2010

The mouse attentional-set-shifting task: a method for assaying successful cognitive aging?

Cogn Affect Behav Neurosci 2010 May;10(2):243-51

University of California, San Diego, La Jolla, California 92093-0804, USA.

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http://dx.doi.org/10.3758/CABN.10.2.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877277PMC
May 2010

5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition.

Pharmacol Biochem Behav 2009 Sep 31;93(3):349-53. Epub 2009 May 31.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, United States.

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http://dx.doi.org/10.1016/j.pbb.2009.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724836PMC
September 2009

5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice.

Neuropsychopharmacology 2009 Jul 25;34(8):1958-67. Epub 2009 Mar 25.

Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1038/npp.2009.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697271PMC
July 2009

5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition.

Pharmacol Biochem Behav 2009 Sep 31;93(3):349-53. Epub 2009 May 31.

Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, United States.

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http://dx.doi.org/10.1016/j.pbb.2009.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724836PMC
September 2009

CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues.

Neuropsychopharmacology 2009 May 19;34(6):1494-503. Epub 2008 Nov 19.

Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr. MC0804, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1038/npp.2008.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900918PMC
May 2009

Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors.

Psychopharmacology (Berl) 2008 Nov 8;201(1):55-66. Epub 2008 Jul 8.

Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1007/s00213-008-1247-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929165PMC
November 2008

Spontaneous nicotine withdrawal potentiates the effects of stress in rats.

Neuropsychopharmacology 2008 Aug 21;33(9):2131-8. Epub 2007 Nov 21.

Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA 92093-0603, USA.

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http://dx.doi.org/10.1038/sj.npp.1301607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648847PMC
August 2008

Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating.

Pharmacol Biochem Behav 2007 Mar 31;86(3):550-8. Epub 2007 Jan 31.

Department of Psychopharmacology, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.pbb.2007.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892615PMC
March 2007

Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice.

Neuropsychopharmacology 2006 Nov 19;31(11):2349-58. Epub 2006 Jul 19.

Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1038/sj.npp.1301161DOI Listing
November 2006

Role of corticotropin releasing factor in anxiety disorders: a translational research perspective.

Horm Behav 2006 Nov 25;50(4):550-61. Epub 2006 Jul 25.

Department of Psychiatry, University of California, San Diego, USA.

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http://dx.doi.org/10.1016/j.yhbeh.2006.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884405PMC
November 2006

Anxiogenic treatments do not increase fear-potentiated startle in mice.

Biol Psychiatry 2005 Jan;57(1):33-43

Departments of Psychiatry and Neurosciences, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1016/j.biopsych.2004.10.006DOI Listing
January 2005

Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice.

Psychopharmacology (Berl) 2003 Nov 4;170(2):178-87. Epub 2003 Jul 4.

Department of Neurosciences, University of California San Diego, 9500 Gilman Drive, Mail Code 0804, La Jolla, CA 92093-0804, USA.

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http://dx.doi.org/10.1007/s00213-003-1535-6DOI Listing
November 2003

GABA-A and 5-HT1A receptor agonists block expression of fear-potentiated startle in mice.

Neuropsychopharmacology 2003 Apr 3;28(4):654-63. Epub 2002 Oct 3.

Department of Neurosciences, University of California, San Diego, La Jolla 92093-0804, USA.

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http://dx.doi.org/10.1038/sj.npp.1300079DOI Listing
April 2003