Victor de Ledinghen

Victor de Ledinghen

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Victor de Ledinghen

Publications by authors named "Victor de Ledinghen"

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Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2019 Sep 28. Epub 2019 Sep 28.

Centre d'Investigation de la Fibrose Hépatique, Bordeaux University Hospital, Pessac, France; INSERM U1053, Bordeaux University, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.09.027DOI Listing
September 2019

Hepatitis C virus infection impacts work productivity and fatigue: An epidemiologic real-life study.

Ann Hepatol 2019 Sep - Oct;18(5):708-714. Epub 2019 May 30.

Hepatology Unit, University Hospital Montpellier, Montpellier, France.

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http://dx.doi.org/10.1016/j.aohep.2019.04.015DOI Listing
May 2019

The R178Q mutation is a recurrent cause of hemochromatosis and is associated with a novel pathogenic mechanism.

Haematologica 2018 11 12;103(11):1796-1805. Epub 2018 Jul 12.

UMR1078, INSERM, Université Bretagne Loire - Université de Bretagne Occidentale, Etablissement Français du Sang - Bretagne, Institut Brestois Santé-Agro-Matière, Brest, France

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http://dx.doi.org/10.3324/haematol.2018.189845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278975PMC
November 2018

Reply to: "Non-invasive prediction of oesophageal varices in patients with cirrhosis secondary to non-alcoholic fatty liver disease".

J Hepatol 2018 11 5;69(5):1203-1204. Epub 2018 Sep 5.

Sezione di Gastroenterologia e Epatologia, Di.Bi.M.I.S, Università di Palermo, Italy; Centre d'Investigation de la Fibrose Hépatique, INSERM U1053, Hôpital Haut-Lévêque, Bordeaux University Hospital, Pessac, France.

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http://dx.doi.org/10.1016/j.jhep.2018.08.017DOI Listing
November 2018

French Patients with Hepatitis C Treated with Direct-Acting Antiviral Combinations: The Effect on Patient-Reported Outcomes.

Value Health 2018 10 21;21(10):1218-1225. Epub 2018 Feb 21.

Department of Medicine, Center for Liver Diseases, Inova Fairfax Hospital, Falls Church, VA, USA; Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, VA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10983015183018
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http://dx.doi.org/10.1016/j.jval.2018.01.006DOI Listing
October 2018

Noninvasive biomarkers in NAFLD and NASH - current progress and future promise.

Nat Rev Gastroenterol Hepatol 2018 08;15(8):461-478

University of Buenos Aires, Institute of Medical Research A Lanari, Buenos Aires, Argentina.

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http://www.nature.com/articles/s41575-018-0014-9
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http://dx.doi.org/10.1038/s41575-018-0014-9DOI Listing
August 2018

A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis.

N Engl J Med 2018 Jun;378(23):2171-2181

From the Reference Center for Inflammatory Biliary Diseases and Autoimmune Hepatitis, Hepatology and Gastroenterology Department, Saint-Antoine University Hospital, Assistance Publique-Hôpitaux de Paris (APHP) (C.C., O.C., S.L., F.G., R.P.), INSERM Unité Mixte de Recherche (UMR) S938 (C.C., O.C., S.L., R.P.) and the Biochemistry Laboratory (L.H., D.R.), Saint-Antoine University Hospital, APHP, INSERM Unité 1157/UMR 7203, Sorbonne University, the Biochemistry Laboratory, Tenon University Hospital, APHP (G.L.), and the Immunology Laboratory, INSERM UMR S996, Bichat University Hospital, APHP (L.C., S.C.-M.), Paris-Sud University, the Department of Clinical Pharmacology and Clinical Research Platform of the East of Paris, APHP (A.R., F.-H.A., T.S.), and Sorbonne University (T.S.), Paris, the Hepatology and Gastroenterology Department, Rouen University Hospital, Rouen (O.G.), the Hepatology and Gastroenterology Department, Pontchaillou University Hospital, Rennes (A.L.G.), the Hepatology and Gastroenterology Department, University Hospitals of Strasbourg, Institute of Viral and Liver Diseases, INSERM Unité 1110, Laboratory of Excellence HepSYS, University of Strasbourg, Strasbourg (F.H.), the Hepatology and Gastroenterology Department, Claude Huriez University Hospital, Lille (P.M.), the Hepatology and Gastroenterology Department, Orleans Hospital, Orleans (P.P.), the Hepatology and Gastroenterology Department, Dijon Bourgogne University Hospital, Dijon (A.M.), the Hepatology and Gastroenterology Department, University Hospital of Poitiers, Poitiers (C.S.), the Hepatology and Gastroenterology Department, Estaing University Hospital, Clermont-Ferrand (A.A.), the Hepatology and Gastroenterology Department, University Hospital of Limoges, Limoges (M.D.-G.), the Hepatology and Gastroenterology Department, Saint-Eloi University Hospital, Montpellier (D.L.), the Hepatology Department, Beaujon University Hospital, Clichy (O.R.), the Hepatology and Gastroenterology Department, Brabois University Hospital, Nancy (J.-P.B.), the Hepatology and Gastroenterology Department, University Hospital of Angers, Hemodynamics, Interaction, Fibrosis, and Tumor Invasiveness in Hepatic and Digestive Organs Laboratory, Unité Propre de Recherche de l'Enseignement Supérieur 3859, Structures Fédératives de Recherche 4208, Bretagne Loire University, Angers (J.B.), the Hepatology and Gastroenterology Department, Haut-Lévêque University Hospital, Pessac (V.L.), the Hepatology and Gastroenterology Department, Robert Debré University Hospital, Reims (A.H.-B.), the Hepatology and Gastroenterology Department, University Hospital of Amiens, Amiens (E.N.-K.), the Hepatology and Gastroenterology Department, Croix-Rousse University Hospital, Lyon (F.Z.), the Hepatology and Gastroenterology Department, University Hospital of Caen, Caen (I.O.-H.), the Hepatology and Gastroenterology Department, Michallon University Hospital, Grenoble (J.-P.Z.), and the Hepatology and Gastroenterology Department, Jean Verdier University Hospital, Bondy (G.N.) - all in France.

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http://dx.doi.org/10.1056/NEJMoa1714519DOI Listing
June 2018

Diagnostic performance of a new noninvasive test for nonalcoholic steatohepatitis using a simplified histological reference.

Eur J Gastroenterol Hepatol 2018 May;30(5):569-577

Groupe Hospitalier Pitié Salpêtrière APHP, Sorbonne Universités, UPMC Univ Paris 06, UMR_S 938, Institute of Cardiometabolism and Nutrition (ICAN).

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http://dx.doi.org/10.1097/MEG.0000000000001064DOI Listing
May 2018

Rapid and large-scale implementation of HCV treatment advances in France, 2007-2015.

BMC Infect Dis 2017 12 20;17(1):784. Epub 2017 Dec 20.

INSERM 1181, Biostatistics, Biomathematics, Pharmacoepidemiology, and Infectious Diseases (B2PHI), Paris, France.

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http://dx.doi.org/10.1186/s12879-017-2889-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738822PMC
December 2017

Albumin Use in Patients With Cirrhosis in France: Results of the "ALBU-LIVE" Survey: A Case for Better EASL Guidelines Diffusion and/or Revision.

J Clin Gastroenterol 2017 Oct;51(9):831-838

*Service d'Hépato-gastroentérologie, de Nutrition et d'Alcoologie, GHPSO, Creil †Service d'Hépato-gastroentérologie, Centre Hospitalier de Gonesse, Gonesse ‡Service d'Hépato-gastroentérologie, CHRU La Cavale Blanche, Brest §Service d'Hépatologie, CHRU Jean Minjoz, Besançon ∥Service d'Hépato-gastroentérologie, CHU, Caen ¶Service d'Hépatologie, CHRU, Lille #Service d'Hépatologie, CHU Cochin §§Service d'Hépatologie, CHU Pitié-Salpêtrière ‡‡‡Service d'Hépatologie, CHU Saint-Antoine ∥∥∥Service d'Hépato-gastroentérologie, CHU Tenon, Paris **Service d'Hépato-gastroentérologie, Centre Hospitalier, Tourcoing ††Service d'Hépatologie, Centre Hépatobiliaire, Villejuif ‡‡Service d'Hépato-gastroentérologie †††Service de Médecine Interne, CHU, Toulouse ∥∥Service d'Hépatologie, CHU Beaujon, Clichy-la-Garenne ¶¶Service d'Hépato-gastroentérologie, Centre Hospitalier, Montfermeil ##Service d'Hépato-gastroentérologie, Centre Hospitalier, Lagny-sur-Marne ***Service d'Hépatologie, CHU, Reims §§§Service d'Hépato-gastroentérologie, Centre Hospitalier, Saint-Denis ¶¶¶Service d'Hépato-gastroentérologie, CHU, Clermont-Ferrand ###Cabinet médical, Montpellier ****Service d'Hépato-gastroentérologie, CHU, Grenoble ††††Service d'Hépato-gastroentérologie, CHU, Pessac ‡‡‡‡Service d'Hépato-gastroentérologie, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France.

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http://dx.doi.org/10.1097/MCG.0000000000000735DOI Listing
October 2017

Validity criteria for the diagnosis of fatty liver by M probe-based controlled attenuation parameter.

J Hepatol 2017 09 12;67(3):577-584. Epub 2017 May 12.

Centre d'Investigation de la Fibrose Hépatique, Hôpital Haut-Lévêque, Bordeaux University Hospital, Pessac, France; INSERM U1053, Bordeaux University, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.05.005DOI Listing
September 2017

Controlled Attenuation Parameter (CAP) with the XL Probe of the Fibroscan: A Comparative Study with the M Probe and Liver Biopsy.

Dig Dis Sci 2017 09 2;62(9):2569-2577. Epub 2017 Jun 2.

Department of Pathology, Physiology and Imaging, Hôpital Beaujon, Clichy, France.

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http://link.springer.com/10.1007/s10620-017-4638-3
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http://dx.doi.org/10.1007/s10620-017-4638-3DOI Listing
September 2017

A Single Test Combining Blood Markers and Elastography is More Accurate Than Other Fibrosis Tests in the Main Causes of Chronic Liver Diseases.

J Clin Gastroenterol 2017 Aug;51(7):639-649

*Virology Department††Department of Hepato-Gastroenterology, Angers University Hospital‡‡HIFIH Laboratory, UNIV Angers, Université Bretagne Loire, Angers†Liver-Gastroenterology Department, University Hospital‡INSERM/UJF U823, IAPC, IAB, University, Grenoble§Liver-Gastroenterology Department, Haut Levêque Hospital∥INSERM 1053, Segalen University¶Department of Pathology, Pellegrin Hospital, Bordeaux University Hospital, Bordeaux#Department of Hepato-Gastroenterology, Amiens University Hospital, Amiens**Infectious Diseases Unit, Paris Center Hospital Group, APHP, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1097/MCG.0000000000000788DOI Listing
August 2017

A stepwise algorithm using an at-a-glance first-line test for the non-invasive diagnosis of advanced liver fibrosis and cirrhosis.

J Hepatol 2017 06 12;66(6):1158-1165. Epub 2017 Jan 12.

Hepatology Department, University Hospital, Angers, France; HIFIH Laboratory, UPRES 3859, SFR 4208, Bretagne Loire University, Angers, France.

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http://dx.doi.org/10.1016/j.jhep.2017.01.003DOI Listing
June 2017

Reply.

Hepatology 2017 06 28;65(6):2128. Epub 2017 Apr 28.

Centre d'Investigation de la Fibrose Hépatique, Hôpital Haut-Lévêque, Bordeaux University Hospital, Pessac, France.

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http://dx.doi.org/10.1002/hep.29065DOI Listing
June 2017

Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection.

N Engl J Med 2017 06;376(22):2134-2146

From Hospital Saint Joseph, Marseille (M.B.), and University Hospital of Bordeaux, Pessac (V.L.) - both in France; Henry Ford Health System, Detroit (S.C.G.); Northwestern University, Chicago (S.L.F.); Ottawa Hospital Research Institute, Ottawa (C.L.C.), and St. Paul's Hospital, Vancouver, BC (A.R.) - both in Canada; Huntington Medical Research Institutes, Pasadena (M.T.), Cedars-Sinai Medical Center, Los Angeles (T.T.T.), and Gilead Sciences, Foster City (R.H.H., L.M.S., H.D.-S., E.S., J.Z., K.C.H., G.M.S., D.M.B., J.G.M.) - all in California; Digestive Disease Associates, Catonsville, MD (N.R.); Baylor College of Medicine, Houston (J.M.V.); Monash Health and Monash University, Clayton, VIC (S.P.), and Royal Prince Alfred Hospital, Sydney (S.I.S.) - both in Australia; Icahn School of Medicine at Mount Sinai (M.B.B.) and Columbia University Medical Center (E.C.V.) - both in New York; ifi-Institute for Interdisciplinary Medicine, Hamburg (P.B.), Hannover Medical School, Hannover (M.P.M.), and Johann Wolfgang Goethe University Medical Center, Frankfurt (S.Z.) - all in Germany; University of Washington (C.S.L.) and Swedish Medical Center (K.V.K.) - both in Seattle; Gastro One, Germantown, TN (Z.H.Y.); Beth Israel Deaconess Medical Center, Boston (M.P.C.); University of Miami, Miami (E.R.S.); and University of Pennsylvania, Philadelphia (K.R.R.).

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http://dx.doi.org/10.1056/NEJMoa1613512DOI Listing
June 2017

Real-World Efficacy of Daclatasvir and Sofosbuvir, With and Without Ribavirin, in HIV/HCV Coinfected Patients With Advanced Liver Disease in a French Early Access Cohort.

J Acquir Immune Defic Syndr 2017 05;75(1):97-107

1Department of Infectious and Tropical Diseases, Hôpitaux Universitaires Saint-Antoine, Assistance Publique Hôpitaux de Paris (APHP), Paris, France; 2Sorbonne Universités, INSERM, UPMC Univ Paris 06, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP UMRS 1136), Paris, France; 3Hepatology Unit, Cochin Hospital, APHP, INSERM USM20, Pasteur Institute, Paris, France; 4Department of Infectious Diseases, CHU de la Conception, Marseilles, France; 5Department of Hepato-gastroenterology, CHU Purpan, Toulouse, France; 6Department of Internal Medicine and COREVIH PACA-EST, CHU Archet, Nice, France; 7Hepatobiliary Centre, CHU Paul-Brousse, Villejuif, France; 8Department of Infectious and Tropical Diseases, CHU Pitié-Salpêtrière, Paris, France; 9Department of Infectious and Tropical Diseases, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France; 10Department of Infectious and Tropical Diseases, Bichat-Claude Bernard Hospital, Paris, France; 11Department of Clinical Immunology, Georges-Pompidou European Hospital, Paris, France; 12Department of Hepato-gastroenterology, CHU de Montpellier, Montpellier, France; 13Department of Infectious and Tropical Diseases, Hôpitaux Universitaires Tenon, APHP, Paris, France; 14Department of Infectious and Tropical Diseases, CHU Perpignan, Perpignan, France; 15Department of Clinical Immunology, CHU Henri Mondor, Créteil, France; 16Department of Hemato-oncology, CH Aix-en-Provence, Aix-en-Provence, France; 17Department of Infectious Diseases, CHU Toulon, Toulon, France; 18Department of Infectious and Tropical Diseases, CHU Hôtel Dieu, Nantes, France; 19Department of Infectious Diseases, Raymond Poincaré Hospital, APHP, Garches, France; 20Department of Internal Medicine, CHD La Roche-sur-Yon, La Roche-sur-Yon, France; 21Department of Hepato-gastroenterology, CHU Grenoble Alpes, Grenoble, France; 22Hepatic Fibrosis Investigation Centre, Haut-Lévêque Hospital, CHU de Bordeaux, Pessac, France; 23INSERM U1223, Pasteur Institute, Paris-Descartes University and Hepatology Department, Cochin Hospital, Paris, France; 24INSERM U1219, ISPED University of Bordeaux, Bordeaux, France; 25Bristol-Myers Squibb Research and Development, Princeton, NJ; 26Bristol-Myers Squibb Research and Development, Rueil-Malmaison, Paris, France; and 27Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1097/QAI.0000000000001342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389585PMC
May 2017

Impact of Surgery and Valvuloplasty on Liver Stiffness in a Patient With Pericarditis and Pulmonary Valvulopathy.

World J Pediatr Congenit Heart Surg 2017 01 23;8(1):103-105. Epub 2016 Jun 23.

1 Department of pediatric and congenital cardiology, University Hospital of Bordeaux, Pessac, France.

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http://dx.doi.org/10.1177/2150135115614575DOI Listing
January 2017

Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease.

J Hepatol 2016 09 2;65(3):570-8. Epub 2016 May 2.

Centre d'Investigation de la Fibrose Hépatique, Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, Pessac, France; INSERM U1053, Université Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1016/j.jhep.2016.04.023DOI Listing
September 2016

Diagnostic performance of controlled attenuation parameter for predicting steatosis grade in chronic hepatitis B.

Ann Hepatol 2015 Nov-Dec;14(6):826-36

Department of Hepatology and INSERM U773-CRB3, Hôpital Beaujon, APHP, University of Paris 7, Clichy, France.

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http://dx.doi.org/10.5604/16652681.1171762DOI Listing
July 2016

Reply to: "New imaging assisted methods for liver fibrosis quantification: Is it really favorable to classical transient elastography?".

J Hepatol 2015 Sep 14;63(3):767. Epub 2015 May 14.

University Hospital, Hepatology Unit, Hôpital de Haut Lévêque, Pessac, France.

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http://dx.doi.org/10.1016/j.jhep.2015.05.002DOI Listing
September 2015

Liver stiffness measurements for evaluation of central venous pressure in congenital heart diseases.

Heart 2015 Sep 17;101(18):1499-504. Epub 2015 Jun 17.

Department of Pediatric and Congenital Cardiology, University Hospital of Bordeaux, Pessac, France INSERM 1053, Université Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1136/heartjnl-2014-307385DOI Listing
September 2015

Liver and spleen elastography using supersonic shear imaging for the non-invasive diagnosis of cirrhosis severity and oesophageal varices.

Dig Liver Dis 2015 Aug 20;47(8):695-701. Epub 2015 Apr 20.

INSERM U1053, Université Bordeaux, Bordeaux, France; Centre d'investigation de la fibrose hépatique, Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, Pessac, France.

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http://dx.doi.org/10.1016/j.dld.2015.04.008DOI Listing
August 2015

MR relaxometry in chronic liver diseases: Comparison of T1 mapping, T2 mapping, and diffusion-weighted imaging for assessing cirrhosis diagnosis and severity.

Eur J Radiol 2015 Aug 19;84(8):1459-1465. Epub 2015 May 19.

INSERM U1053, Université Bordeaux, Bordeaux, France; Centre D'investigation de la Fibrose Hépatique, Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, 1 Avenue de Magellan, 33604 Pessac, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2015.05.019DOI Listing
August 2015

Cirrhosis Diagnosis and Liver Fibrosis Staging: Transient Elastometry Versus Cirrhosis Blood Test.

J Clin Gastroenterol 2015 Jul;49(6):512-9

*Liver-Gastroenterology Department, CHU Angers †HIFIH Laboratory, LUNAM University, Angers ‡Liver-Gastroenterology Department, University Hospital §INSERM/UJF U823, IAPC, IAB, University, Grenoble ∥Liver-Gastroenterology Unit, University Hospital, Pessac ¶INSERM U1053, Bordeaux University, Bordeaux, France.

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http://dx.doi.org/10.1097/MCG.0000000000000138DOI Listing
July 2015

Non-invasive assessment of liver fibrosis with impulse elastography: comparison of Supersonic Shear Imaging with ARFI and FibroScan®.

J Hepatol 2014 Sep 9;61(3):550-7. Epub 2014 May 9.

INSERM U1053, Université Bordeaux, Bordeaux, France; Centre d'investigation de la fibrose hépatique, Hôpîtal Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, 1 Avenue de Magellan, 33604 Pessac, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01688278140030
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http://dx.doi.org/10.1016/j.jhep.2014.04.044DOI Listing
September 2014