Victor Segura

Victor Segura

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Victor Segura

Victor Segura

Publications by authors named "Victor Segura"

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Identification of Coding and Long Noncoding RNAs Differentially Expressed in Tumors and Preferentially Expressed in Healthy Tissues.

Cancer Res 2019 Oct 6;79(20):5167-5180. Epub 2019 Aug 6.

University of Navarra (UNAV). Center for Applied Medical Research (CIMA). Program of Gene Therapy and Hepatology. Pamplona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0400DOI Listing
October 2019

DeepMSPeptide: peptide detectability prediction using deep learning.

Bioinformatics 2019 Sep 14. Epub 2019 Sep 14.

Bioinformatics Platform, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btz708DOI Listing
September 2019

MiTPeptideDB: a proteogenomic resource for the discovery of novel peptides.

Bioinformatics 2019 Jun 27. Epub 2019 Jun 27.

Bioinformatics Platform, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btz530DOI Listing
June 2019

The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma.

Clin Cancer Res 2019 May 28;25(10):3176-3187. Epub 2019 Jan 28.

Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigación Sanitaria de Navarra (IDISNA), CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1597DOI Listing
May 2019

Proteogenomics in the context of the Human Proteome Project (HPP).

Expert Rev Proteomics 2019 Mar 28;16(3):267-275. Epub 2019 Jan 28.

a Bioinformatics Platform, Center for Applied Medical Research , University of Navarra , Pamplona , Spain.

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http://dx.doi.org/10.1080/14789450.2019.1571916DOI Listing
March 2019

Erratum to "A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction" [J Hepatol 67 (2017) 669-679].

J Hepatol 2018 07;69(1):262-264

Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Calle Irunlarrea 3, Pamplona 31008, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.04.003DOI Listing
July 2018

Deregulation of in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells.

Oncotarget 2018 Feb 5;9(16):12842-12852. Epub 2018 Feb 5.

Laboratory of Myeloproliferative Syndromes, Oncology Area, Foundation for Applied Medical Research, IDISNA, CIBERONC, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.18632/oncotarget.24401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849178PMC
February 2018

Methylation changes and pathways affected in preterm birth: a role for SLC6A3 in neurodevelopment.

Epigenomics 2018 01 27;10(1):91-103. Epub 2017 Nov 27.

Department of Nutrition, Food Sciences & Physiology, Universidad de Navarra, Irunlarrea 1, 31008 Pamplona, Spain.

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http://dx.doi.org/10.2217/epi-2017-0082DOI Listing
January 2018

A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction.

J Hepatol 2017 10 18;67(4):669-679. Epub 2017 May 18.

Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Calle Irunlarrea 3, Pamplona 31008, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.05.010DOI Listing
October 2017

Proteogenomic Analysis of Single Amino Acid Polymorphisms in Cancer Research.

Adv Exp Med Biol 2016 ;926:93-113

Proteomics and Bioinformatics Unit, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://link.springer.com/10.1007/978-3-319-42316-6_7
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http://dx.doi.org/10.1007/978-3-319-42316-6_7DOI Listing
June 2017

X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver.

Gastroenterology 2017 04 9;152(5):1203-1216.e15. Epub 2017 Jan 9.

Department of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.12.040DOI Listing
April 2017

Progress and pitfalls in finding the 'missing proteins' from the human proteome map.

Expert Rev Proteomics 2017 01 2;14(1):9-14. Epub 2016 Dec 2.

a Proteomics and Bioinformatics Laboratory, CIMA , University of Navarra , Pamplona , Spain.

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http://dx.doi.org/10.1080/14789450.2017.1265450DOI Listing
January 2017

Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication.

EMBO Rep 2016 07 9;17(7):1013-28. Epub 2016 Jun 9.

Department of Gene Therapy and Hepatology, Center for Applied Medical Research (CIMA) and IdiSNA Navarra Institute for Health Research University of Navarra, Pamplona, Spain

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http://dx.doi.org/10.15252/embr.201541763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931568PMC
July 2016

Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.

Antimicrob Agents Chemother 2015 Dec 28;59(12):7581-92. Epub 2015 Sep 28.

Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CIBERES, Madrid, Spain Instituto de Agrobiotecnología, CSIC-Universidad Pública Navarra-Gobierno Navarra, Mutilva, Spain

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http://dx.doi.org/10.1128/AAC.01278-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649218PMC
December 2015

Vitamin D-binding protein as a biomarker of active disease in acute intermittent porphyria.

J Proteomics 2015 Sep 13;127(Pt B):377-85. Epub 2015 May 13.

Hepatology Area, Centre for Applied Medical Research, University of Navarra, Spain; CIBEREHD, University Clinic Navarra, Instituto de Salud Carlos III, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18743919153000
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http://dx.doi.org/10.1016/j.jprot.2015.05.004DOI Listing
September 2015

Proteogenomics Dashboard for the Human Proteome Project.

J Proteome Res 2015 Sep 16;14(9):3738-49. Epub 2015 Jul 16.

ProteoRed-ISCIII, National Center for Biotechnology-CSIC (CNB) , C/Darwin 3, Madrid 28049, Spain.

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http://dx.doi.org/10.1021/acs.jproteome.5b00466DOI Listing
September 2015

Virotherapy with a Semliki Forest Virus-Based Vector Encoding IL12 Synergizes with PD-1/PD-L1 Blockade.

Cancer Immunol Res 2015 May 17;3(5):449-54. Epub 2015 Feb 17.

Division of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), and University Clinic, University of Navarra, Pamplona, Navarra, Spain.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0216DOI Listing
May 2015

Prediction of a missing protein expression map in the context of the human proteome project.

J Proteome Res 2015 Mar 5;14(3):1350-60. Epub 2015 Feb 5.

Proteomics, Genomics and Bioinformatics Unit, §Division of Hepatology and Gene Therapy, Center for Applied Medical Research, University of Navarra , Pamplona 31008, Spain.

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http://dx.doi.org/10.1021/pr500850uDOI Listing
March 2015

Long Non-Coding RNA BST2/BISPR is Induced by IFN and Regulates the Expression of the Antiviral Factor Tetherin.

Front Immunol 2014 9;5:655. Epub 2015 Jan 9.

Department of Gene Therapy and Hepatology, Center for Applied Medical Research (CIMA), University of Navarra , Pamplona , Spain.

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http://dx.doi.org/10.3389/fimmu.2014.00655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288319PMC
January 2015

Type I Interferon Regulates the Expression of Long Non-Coding RNAs.

Front Immunol 2014 6;5:548. Epub 2014 Nov 6.

Department of Gene therapy and Hepatology, Center for Applied Medical Research (CIMA), University of Navarra , Pamplona , Spain.

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http://dx.doi.org/10.3389/fimmu.2014.00548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222131PMC
November 2014

Base pairing interaction between 5'- and 3'-UTRs controls icaR mRNA translation in Staphylococcus aureus.

PLoS Genet 2013 19;9(12):e1004001. Epub 2013 Dec 19.

Laboratory of Microbial Biofilms. Instituto de Agrobiotecnología (IDAB). Universidad Pública de Navarra-CSIC-Gobierno de Navarra. Campus de Arrosadía. Pamplona, Spain.

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http://dx.doi.org/10.1371/journal.pgen.1004001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868564PMC
August 2014

A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool.

Neuro Oncol 2014 Apr 16;16(4):520-7. Epub 2014 Jan 16.

Instituto Biodonostia and Hospital Universitario Donostia, San Sebastian, Spain (L.M., N.S., C.B., I.R., A.M., A.L.-M.); Center for Applied Medical Research (CIMA), Pamplona, Spain (E.G., V.S.); Clínica Universidad de Navarra, Pamplona, Spain (J.G.P-L., M.G-H., P.J., S.T., R.D.-V., J.R., A.G., E.X., M.M.A.); Polymat, University of the Basque Country, San Sebastian, Spain (A.A.); IMMA-CIOCC, Fundación Hospital de Madrid, Madrid, Spain (A.A.); Fundación Jimenez-Díaz, Madrid, Spain (J.G.-F.); Complejo Hospitalario de Navarra, Pamplona, Spain (T.T., I.Z.); Pitié-Salpètriere, Paris, France (S.P., J.Y.D.).

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http://dx.doi.org/10.1093/neuonc/not218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956347PMC
April 2014

Functional interpretation of microRNA-mRNA association in biological systems using R.

Comput Biol Med 2014 Jan 13;44:124-31. Epub 2013 Nov 13.

Unit of Proteomics, Genomics and Bioinformatics, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2013.11.001DOI Listing
January 2014

Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature.

Blood 2013 Dec 9;122(24):3982-92. Epub 2013 Oct 9.

Department of Cardiovascular Sciences, Molecular and Vascular Biology Research Unit, Endothelial Cell Biology Unit, KU Leuven, Leuven, Belgium;

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http://dx.doi.org/10.1182/blood-2013-02-483255DOI Listing
December 2013

Atrial fibrillation in pigs induces left atrial endocardial transcriptional remodelling.

Thromb Haemost 2012 Oct 26;108(4):742-9. Epub 2012 Jul 26.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1160/TH12-05-0285DOI Listing
October 2012

Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury.

J Proteomics 2012 Oct 21;75(18):5783-92. Epub 2012 Aug 21.

Center for Applied Medical Research (CIMA), University of Navarra. Pamplona, Spain.

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http://dx.doi.org/10.1016/j.jprot.2012.08.009DOI Listing
October 2012

Wavelet-based detection of transcriptional activity on a novel Staphylococcus aureus tiling microarray.

BMC Bioinformatics 2012 Sep 5;13:222. Epub 2012 Sep 5.

Genomics, Proteomics and Bioinformatics Unit, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1186/1471-2105-13-222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563573PMC
September 2012

Genome-wide antisense transcription drives mRNA processing in bacteria.

Proc Natl Acad Sci U S A 2011 Dec 28;108(50):20172-7. Epub 2011 Nov 28.

Laboratory of Microbial Biofilms, Instituto de Agrobiotecnología, Consejo Superior de Investigaciones Científicas-Universidad Pública de Navarra-Gobierno de Navarra, 31006 Pamplona, Spain.

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http://dx.doi.org/10.1073/pnas.1113521108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250193PMC
December 2011

A signature of six genes highlights defects on cell growth and specific metabolic pathways in murine and human hepatocellular carcinoma.

Funct Integr Genomics 2011 Sep 12;11(3):419-29. Epub 2011 May 12.

Division of Hepatology and Gene Therapy, Proteomics, Genomics & Bioinformatics Unit, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1007/s10142-011-0230-7DOI Listing
September 2011

Prohibitin deficiency blocks proliferation and induces apoptosis in human hepatoma cells: molecular mechanisms and functional implications.

Proteomics 2010 Apr;10(8):1609-20

Division of Hepatology and Gene Therapy, Proteomics Unit, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1002/pmic.200900757DOI Listing
April 2010

Genome-wide proximal promoter analysis and interpretation.

Methods Mol Biol 2010 ;593:157-74

CEIT, Centro de Estudios e Investigaciones Técnicas de Gipuzkoa, San Sebastian, Spain.

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http://dx.doi.org/10.1007/978-1-60327-194-3_8DOI Listing
February 2010

VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop.

Exp Cell Res 2010 Feb 16;316(4):554-67. Epub 2009 Dec 16.

Laboratory of Novel Therapeutic Targets, Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Avda. Pio XII, 55, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1016/j.yexcr.2009.11.020DOI Listing
February 2010

Oncostatin M enhances the antiviral effects of type I interferon and activates immunostimulatory functions in liver epithelial cells.

J Virol 2009 Apr 21;83(7):3298-311. Epub 2009 Jan 21.

Division of Hepatology and Gene Therapy, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1128/JVI.02167-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655580PMC
April 2009

FactorY, a bioinformatic resource for genome-wide promoter analysis.

Comput Biol Med 2009 Apr 9;39(4):385-7. Epub 2009 Mar 9.

Unit of Proteomics, Genomics and Bioinformatics, CIMA, Pamplona 31008, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S00104825090002
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http://dx.doi.org/10.1016/j.compbiomed.2009.01.008DOI Listing
April 2009

Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.

Cancer Res 2009 Feb 3;69(4):1358-67. Epub 2009 Feb 3.

Division of Hepatology and Gene Therapy,CIMA and CIBERehd, University Clinic, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2545DOI Listing
February 2009

Methylseleninic acid enhances the effect of etoposide to inhibit prostate cancer growth in vivo.

Int J Cancer 2007 Sep;121(6):1197-204

Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1002/ijc.22764DOI Listing
September 2007

Correlation between gene expression and GO semantic similarity.

IEEE/ACM Trans Comput Biol Bioinform 2005 Oct-Dec;2(4):330-8

Strathmore University, Ole Sangale Road, Madaraka Estate, PO Box 59857, 00200 Nairobi, Kenya.

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http://dx.doi.org/10.1109/TCBB.2005.50DOI Listing
October 2006

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

Bioinformatics 2003 Nov;19(16):2158-60

Department of Internal Medicine, Unit of Proteomics, Genomics and Bioinformatics, University of Navarra, Pamplona-31008, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btg291DOI Listing
November 2003