Victor Quesada

Victor Quesada

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Victor Quesada

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Differential mechanisms of tolerance to extreme environmental conditions in tardigrades.

Sci Rep 2019 Oct 17;9(1):14938. Epub 2019 Oct 17.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006, Oviedo, Spain.

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http://dx.doi.org/10.1038/s41598-019-51471-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797769PMC
October 2019

Genome Sequencing and Analysis Methods in Chronic Lymphocytic Leukemia.

Methods Mol Biol 2019 ;1881:319-325

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1007/978-1-4939-8876-1_22DOI Listing
July 2019

Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome.

Nat Med 2019 03 18;25(3):423-426. Epub 2019 Feb 18.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1038/s41591-018-0338-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546610PMC
March 2019

Transcriptional and Post-transcriptional Regulation of Organellar Gene Expression (OGE) and Its Roles in Plant Salt Tolerance.

Int J Mol Sci 2019 Feb 28;20(5). Epub 2019 Feb 28.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://dx.doi.org/10.3390/ijms20051056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429081PMC
February 2019

The Characterization of Arabidopsis Mutants Reveals a New Role for mTERF6 in Tolerance to Abiotic Stress.

Int J Mol Sci 2018 Aug 14;19(8). Epub 2018 Aug 14.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://www.mdpi.com/1422-0067/19/8/2388
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http://dx.doi.org/10.3390/ijms19082388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121570PMC
August 2018

nVenn: generalized, quasi-proportional Venn and Euler diagrams.

Bioinformatics 2018 07;34(13):2322-2324

Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1093/bioinformatics/bty109DOI Listing
July 2018

Arabidopsis mTERF6 is required for leaf patterning.

Plant Sci 2018 Jan 8;266:117-129. Epub 2017 Nov 8.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.plantsci.2017.11.003DOI Listing
January 2018

Emerging Roles of Mitochondrial Ribosomal Proteins in Plant Development.

Int J Mol Sci 2017 Dec 2;18(12). Epub 2017 Dec 2.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://dx.doi.org/10.3390/ijms18122595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751198PMC
December 2017

USP39 Deubiquitinase Is Essential for Oncogene-driven Cancer.

J Biol Chem 2017 03 1;292(10):4164-4175. Epub 2017 Feb 1.

From the Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain,

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http://dx.doi.org/10.1074/jbc.M116.762757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354494PMC
March 2017

Novel mutations cause an aggressive atypical neonatal progeria without progerin accumulation.

J Med Genet 2016 Nov 22;53(11):776-785. Epub 2016 Jun 22.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1136/jmedgenet-2015-103695DOI Listing
November 2016

The roles of mitochondrial transcription termination factors (MTERFs) in plants.

Authors:
Víctor Quesada

Physiol Plant 2016 Jul 14;157(3):389-99. Epub 2016 Mar 14.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202, Elche, Spain.

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http://dx.doi.org/10.1111/ppl.12416DOI Listing
July 2016

Adaptive Evolution Favoring KLK4 Downregulation in East Asians.

Mol Biol Evol 2016 Jan 29;33(1):93-108. Epub 2015 Sep 29.

Instituto de Investigação e Inovação em Saúde, Universidade do Porto (I3S), Porto, Portugal Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal

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http://dx.doi.org/10.1093/molbev/msv199DOI Listing
January 2016

The Degradome database: expanding roles of mammalian proteases in life and disease.

Nucleic Acids Res 2016 Jan 8;44(D1):D351-5. Epub 2015 Nov 8.

From the Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain

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http://dx.doi.org/10.1093/nar/gkv1201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702854PMC
January 2016

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

Nat Commun 2015 Dec 9;6:10001. Epub 2015 Dec 9.

CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1038/ncomms10001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682041PMC
December 2015

Plastid control of abaxial-adaxial patterning.

Sci Rep 2015 Nov 2;5:15975. Epub 2015 Nov 2.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://dx.doi.org/10.1038/srep15975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629159PMC
November 2015

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.

Blood 2015 Jul 1;126(2):195-202. Epub 2015 Jun 1.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, Oviedo, Spain;

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http://dx.doi.org/10.1182/blood-2014-10-604959DOI Listing
July 2015

Mutations in the plant-conserved MTERF9 alter chloroplast gene expression, development and tolerance to abiotic stress in Arabidopsis thaliana.

Physiol Plant 2015 Jun 8;154(2):297-313. Epub 2014 Dec 8.

Instituto de Bioingeniería, Universidad Miguel Hernández, Elche 03202, Spain.

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http://dx.doi.org/10.1111/ppl.12307DOI Listing
June 2015

Molecular pathogenesis of CLL and its evolution.

Int J Hematol 2015 Mar 29;101(3):219-28. Epub 2015 Jan 29.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología-IUOPA, Universidad de Oviedo, 33006, Oviedo, Spain.

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http://link.springer.com/content/pdf/10.1007%2Fs12185-015-17
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http://link.springer.com/10.1007/s12185-015-1733-0
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http://dx.doi.org/10.1007/s12185-015-1733-0DOI Listing
March 2015

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.

J Natl Cancer Inst 2015 Feb 13;107(2). Epub 2014 Dec 13.

Affiliations of authors: QIMR Berghofer Medical Research Institute, Brisbane, Australia (LGA, ALP, MG, PJ, JMP, JS, VB, SW, KDR, MSS, GWM, NGM, NKH); Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK (CDRE, TMK, DJA); Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark (KW, AMG); Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK (MH, HSn, DTB, JANB); Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JC, KMB); Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo, Oviedo, Spain (VQ, AJR, CLO); Cancer Genomics Research Laboratory, NCI Frederick, SAIC-Frederick Inc., Frederick MD (XZ, KJ); Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands (RvD, NAG); Department of Clinical Sciences Lund, Division of Oncology and Pathology, Lund University, Lund, Sweden (HO, CI, ÅB, GJ); Translational Genomics Institute, Phoenix, AZ (JMT); University of Sydney at Westmead Millennium Institute, Westmead, Sydney, NSW, Australia (EAH, HSc, GJM); Melanoma Institute Australia, North Sydney, NSW, Australia (EAH, HSc, GJM).

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http://dx.doi.org/10.1093/jnci/dju408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334787PMC
February 2015

Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.

Nat Commun 2013 ;4:2531

1] Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, Oviedo 33006, Spain [2].

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http://dx.doi.org/10.1038/ncomms3531DOI Listing
May 2014

Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome.

BMC Med Genet 2014 May 2;15:51. Epub 2014 May 2.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1186/1471-2350-15-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022398PMC
May 2014

Recurrent gene mutations in CLL.

Adv Exp Med Biol 2013 ;792:87-107

Unidad de Hematopatologia, Departamento de Anatomía Patológica, Hospital Clinic, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/978-1-4614-8051-8_4DOI Listing
February 2014

Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients.

Hum Mol Genet 2013 Jun 14;22(11):2273-82. Epub 2013 Feb 14.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1093/hmg/ddt078DOI Listing
June 2013

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia.

Nat Genet 2013 May 17;45(5):526-30. Epub 2013 Mar 17.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo, Oviedo, Spain.

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http://www.nature.com/articles/ng.2584
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http://dx.doi.org/10.1038/ng.2584DOI Listing
May 2013

The genomic landscape of chronic lymphocytic leukemia: clinical implications.

BMC Med 2013 May 9;11:124. Epub 2013 May 9.

Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo - IUOPA, Oviedo, Spain.

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http://dx.doi.org/10.1186/1741-7015-11-124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655884PMC
May 2013

Arabidopsis MDA1, a nuclear-encoded protein, functions in chloroplast development and abiotic stress responses.

PLoS One 2012 8;7(8):e42924. Epub 2012 Aug 8.

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, Elche, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042924PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414458PMC
February 2013

Next-generation sequencing reveals the secrets of the chronic lymphocytic leukemia genome.

Clin Transl Oncol 2013 Jan 22;15(1):3-8. Epub 2012 Aug 22.

Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1007/s12094-012-0922-zDOI Listing
January 2013

Chronic lymphocytic leukemia with SF3B1 mutation.

N Engl J Med 2012 Jun;366(26):2530

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http://dx.doi.org/10.1056/NEJMc1204033DOI Listing
June 2012

Unveiling plant mTERF functions.

Mol Plant 2012 Mar;5(2):294-6

Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://dx.doi.org/10.1093/mp/sss016DOI Listing
March 2012

Comparative and demographic analysis of orang-utan genomes.

Authors:
Devin P Locke LaDeana W Hillier Wesley C Warren Kim C Worley Lynne V Nazareth Donna M Muzny Shiaw-Pyng Yang Zhengyuan Wang Asif T Chinwalla Pat Minx Makedonka Mitreva Lisa Cook Kim D Delehaunty Catrina Fronick Heather Schmidt Lucinda A Fulton Robert S Fulton Joanne O Nelson Vincent Magrini Craig Pohl Tina A Graves Chris Markovic Andy Cree Huyen H Dinh Jennifer Hume Christie L Kovar Gerald R Fowler Gerton Lunter Stephen Meader Andreas Heger Chris P Ponting Tomas Marques-Bonet Can Alkan Lin Chen Ze Cheng Jeffrey M Kidd Evan E Eichler Simon White Stephen Searle Albert J Vilella Yuan Chen Paul Flicek Jian Ma Brian Raney Bernard Suh Richard Burhans Javier Herrero David Haussler Rui Faria Olga Fernando Fleur Darré Domènec Farré Elodie Gazave Meritxell Oliva Arcadi Navarro Roberta Roberto Oronzo Capozzi Nicoletta Archidiacono Giuliano Della Valle Stefania Purgato Mariano Rocchi Miriam K Konkel Jerilyn A Walker Brygg Ullmer Mark A Batzer Arian F A Smit Robert Hubley Claudio Casola Daniel R Schrider Matthew W Hahn Victor Quesada Xose S Puente Gonzalo R Ordoñez Carlos López-Otín Tomas Vinar Brona Brejova Aakrosh Ratan Robert S Harris Webb Miller Carolin Kosiol Heather A Lawson Vikas Taliwal André L Martins Adam Siepel Arindam Roychoudhury Xin Ma Jeremiah Degenhardt Carlos D Bustamante Ryan N Gutenkunst Thomas Mailund Julien Y Dutheil Asger Hobolth Mikkel H Schierup Oliver A Ryder Yuko Yoshinaga Pieter J de Jong George M Weinstock Jeffrey Rogers Elaine R Mardis Richard A Gibbs Richard K Wilson

Nature 2011 Jan;469(7331):529-33

The Genome Center at Washington University, Washington University School of Medicine, 4444 Forest Park Avenue, Saint Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature09687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060778PMC
January 2011

Noncanonical translation initiation of the Arabidopsis flowering time and alternative polyadenylation regulator FCA.

Plant Cell 2010 Nov 12;22(11):3764-77. Epub 2010 Nov 12.

Department of Cell and Developmental Biology, John Ines Centre, Norfolk NR4 7UH, United Kingdom.

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http://dx.doi.org/10.1105/tpc.110.077990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3015108PMC
November 2010

Comparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals.

BMC Genomics 2010 Apr 1;11:220. Epub 2010 Apr 1.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1186/1471-2164-11-220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865498PMC
April 2010

The genome of a songbird.

Nature 2010 Apr;464(7289):757-62

The Genome Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature08819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187626PMC
April 2010

International network of cancer genome projects.

Authors:
Thomas J Hudson Warwick Anderson Axel Artez Anna D Barker Cindy Bell Rosa R Bernabé M K Bhan Fabien Calvo Iiro Eerola Daniela S Gerhard Alan Guttmacher Mark Guyer Fiona M Hemsley Jennifer L Jennings David Kerr Peter Klatt Patrik Kolar Jun Kusada David P Lane Frank Laplace Lu Youyong Gerd Nettekoven Brad Ozenberger Jane Peterson T S Rao Jacques Remacle Alan J Schafer Tatsuhiro Shibata Michael R Stratton Joseph G Vockley Koichi Watanabe Huanming Yang Matthew M F Yuen Bartha M Knoppers Martin Bobrow Anne Cambon-Thomsen Lynn G Dressler Stephanie O M Dyke Yann Joly Kazuto Kato Karen L Kennedy Pilar Nicolás Michael J Parker Emmanuelle Rial-Sebbag Carlos M Romeo-Casabona Kenna M Shaw Susan Wallace Georgia L Wiesner Nikolajs Zeps Peter Lichter Andrew V Biankin Christian Chabannon Lynda Chin Bruno Clément Enrique de Alava Françoise Degos Martin L Ferguson Peter Geary D Neil Hayes Thomas J Hudson Amber L Johns Arek Kasprzyk Hidewaki Nakagawa Robert Penny Miguel A Piris Rajiv Sarin Aldo Scarpa Tatsuhiro Shibata Marc van de Vijver P Andrew Futreal Hiroyuki Aburatani Mónica Bayés David D L Botwell Peter J Campbell Xavier Estivill Daniela S Gerhard Sean M Grimmond Ivo Gut Martin Hirst Carlos López-Otín Partha Majumder Marco Marra John D McPherson Hidewaki Nakagawa Zemin Ning Xose S Puente Yijun Ruan Tatsuhiro Shibata Michael R Stratton Hendrik G Stunnenberg Harold Swerdlow Victor E Velculescu Richard K Wilson Hong H Xue Liu Yang Paul T Spellman Gary D Bader Paul C Boutros Peter J Campbell Paul Flicek Gad Getz Roderic Guigó Guangwu Guo David Haussler Simon Heath Tim J Hubbard Tao Jiang Steven M Jones Qibin Li Nuria López-Bigas Ruibang Luo Lakshmi Muthuswamy B F Francis Ouellette John V Pearson Xose S Puente Victor Quesada Benjamin J Raphael Chris Sander Tatsuhiro Shibata Terence P Speed Lincoln D Stein Joshua M Stuart Jon W Teague Yasushi Totoki Tatsuhiko Tsunoda Alfonso Valencia David A Wheeler Honglong Wu Shancen Zhao Guangyu Zhou Lincoln D Stein Roderic Guigó Tim J Hubbard Yann Joly Steven M Jones Arek Kasprzyk Mark Lathrop Nuria López-Bigas B F Francis Ouellette Paul T Spellman Jon W Teague Gilles Thomas Alfonso Valencia Teruhiko Yoshida Karen L Kennedy Myles Axton Stephanie O M Dyke P Andrew Futreal Daniela S Gerhard Chris Gunter Mark Guyer Thomas J Hudson John D McPherson Linda J Miller Brad Ozenberger Kenna M Shaw Arek Kasprzyk Lincoln D Stein Junjun Zhang Syed A Haider Jianxin Wang Christina K Yung Anthony Cros Anthony Cross Yong Liang Saravanamuttu Gnaneshan Jonathan Guberman Jack Hsu Martin Bobrow Don R C Chalmers Karl W Hasel Yann Joly Terry S H Kaan Karen L Kennedy Bartha M Knoppers William W Lowrance Tohru Masui Pilar Nicolás Emmanuelle Rial-Sebbag Laura Lyman Rodriguez Catherine Vergely Teruhiko Yoshida Sean M Grimmond Andrew V Biankin David D L Bowtell Nicole Cloonan Anna deFazio James R Eshleman Dariush Etemadmoghadam Brooke B Gardiner Brooke A Gardiner James G Kench Aldo Scarpa Robert L Sutherland Margaret A Tempero Nicola J Waddell Peter J Wilson John D McPherson Steve Gallinger Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Debabrata Mukhopadhyay Lynda Chin Ronald A DePinho Sarah Thayer Lakshmi Muthuswamy Kamran Shazand Timothy Beck Michelle Sam Lee Timms Vanessa Ballin Youyong Lu Jiafu Ji Xiuqing Zhang Feng Chen Xueda Hu Guangyu Zhou Qi Yang Geng Tian Lianhai Zhang Xiaofang Xing Xianghong Li Zhenggang Zhu Yingyan Yu Jun Yu Huanming Yang Mark Lathrop Jörg Tost Paul Brennan Ivana Holcatova David Zaridze Alvis Brazma Lars Egevard Egor Prokhortchouk Rosamonde Elizabeth Banks Mathias Uhlén Anne Cambon-Thomsen Juris Viksna Fredrik Ponten Konstantin Skryabin Michael R Stratton P Andrew Futreal Ewan Birney Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Sancha Martin Jorge S Reis-Filho Andrea L Richardson Christos Sotiriou Hendrik G Stunnenberg Giles Thoms Marc van de Vijver Laura van't Veer Fabien Calvo Daniel Birnbaum Hélène Blanche Pascal Boucher Sandrine Boyault Christian Chabannon Ivo Gut Jocelyne D Masson-Jacquemier Mark Lathrop Iris Pauporté Xavier Pivot Anne Vincent-Salomon Eric Tabone Charles Theillet Gilles Thomas Jörg Tost Isabelle Treilleux Fabien Calvo Paulette Bioulac-Sage Bruno Clément Thomas Decaens Françoise Degos Dominique Franco Ivo Gut Marta Gut Simon Heath Mark Lathrop Didier Samuel Gilles Thomas Jessica Zucman-Rossi Peter Lichter Roland Eils Benedikt Brors Jan O Korbel Andrey Korshunov Pablo Landgraf Hans Lehrach Stefan Pfister Bernhard Radlwimmer Guido Reifenberger Michael D Taylor Christof von Kalle Partha P Majumder Rajiv Sarin T S Rao M K Bhan Aldo Scarpa Paolo Pederzoli Rita A Lawlor Massimo Delledonne Alberto Bardelli Andrew V Biankin Sean M Grimmond Thomas Gress David Klimstra Giuseppe Zamboni Tatsuhiro Shibata Yusuke Nakamura Hidewaki Nakagawa Jun Kusada Tatsuhiko Tsunoda Satoru Miyano Hiroyuki Aburatani Kazuto Kato Akihiro Fujimoto Teruhiko Yoshida Elias Campo Carlos López-Otín Xavier Estivill Roderic Guigó Silvia de Sanjosé Miguel A Piris Emili Montserrat Marcos González-Díaz Xose S Puente Pedro Jares Alfonso Valencia Heinz Himmelbauer Heinz Himmelbaue Victor Quesada Silvia Bea Michael R Stratton P Andrew Futreal Peter J Campbell Anne Vincent-Salomon Andrea L Richardson Jorge S Reis-Filho Marc van de Vijver Gilles Thomas Jocelyne D Masson-Jacquemier Samuel Aparicio Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Hendrik G Stunnenberg Laura van't Veer Douglas F Easton Paul T Spellman Sancha Martin Anna D Barker Lynda Chin Francis S Collins Carolyn C Compton Martin L Ferguson Daniela S Gerhard Gad Getz Chris Gunter Alan Guttmacher Mark Guyer D Neil Hayes Eric S Lander Brad Ozenberger Robert Penny Jane Peterson Chris Sander Kenna M Shaw Terence P Speed Paul T Spellman Joseph G Vockley David A Wheeler Richard K Wilson Thomas J Hudson Lynda Chin Bartha M Knoppers Eric S Lander Peter Lichter Lincoln D Stein Michael R Stratton Warwick Anderson Anna D Barker Cindy Bell Martin Bobrow Wylie Burke Francis S Collins Carolyn C Compton Ronald A DePinho Douglas F Easton P Andrew Futreal Daniela S Gerhard Anthony R Green Mark Guyer Stanley R Hamilton Tim J Hubbard Olli P Kallioniemi Karen L Kennedy Timothy J Ley Edison T Liu Youyong Lu Partha Majumder Marco Marra Brad Ozenberger Jane Peterson Alan J Schafer Paul T Spellman Hendrik G Stunnenberg Brandon J Wainwright Richard K Wilson Huanming Yang

Nature 2010 Apr;464(7291):993-8

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http://dx.doi.org/10.1038/nature08987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902243PMC
April 2010

Lessons from a search for leaf mutants in Arabidopsis thaliana.

Int J Dev Biol 2009 ;53(8-10):1623-34

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, Elche, Alicante, Spain.

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http://dx.doi.org/10.1387/ijdb.072534jpDOI Listing
March 2010

Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.

Hum Mol Genet 2009 Oct 10;18(19):3673-83. Epub 2009 Jul 10.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1093/hmg/ddp315DOI Listing
October 2009

Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.

J Clin Invest 2009 Aug;119(8):2343-58

Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Madrid, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719930PMC
http://dx.doi.org/10.1172/jci37205DOI Listing
August 2009

Proteolytic systems: constructing degradomes.

Methods Mol Biol 2009 ;539:33-47

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.

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http://dx.doi.org/10.1007/978-1-60327-003-8_2DOI Listing
May 2009

The Degradome database: mammalian proteases and diseases of proteolysis.

Nucleic Acids Res 2009 Jan 6;37(Database issue):D239-43. Epub 2008 Sep 6.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1093/nar/gkn570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686449PMC
January 2009

The ABA1 gene and carotenoid biosynthesis are required for late skotomorphogenic growth in Arabidopsis thaliana.

Plant Cell Environ 2008 Feb 7;31(2):227-34. Epub 2007 Dec 7.

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Alicante, Spain.

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http://dx.doi.org/10.1111/j.1365-3040.2007.01759.xDOI Listing
February 2008

The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC.

Mol Cell 2007 Nov;28(3):398-407

Department of Cell and Developmental Biology, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.

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http://dx.doi.org/10.1016/j.molcel.2007.10.018DOI Listing
November 2007

A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infection.

J Virol 2007 Oct 18;81(19):10300-9. Epub 2007 Jul 18.

Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1128/JVI.01149-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045495PMC
October 2007

Visualization of gene expression by fluorescent multiplex reverse transcriptase-PCR amplification.

Methods Mol Biol 2007 ;353:143-52

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Alicante, Spain.

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http://dx.doi.org/10.1385/1-59745-229-7:143DOI Listing
April 2007

Mutations in the RETICULATA gene dramatically alter internal architecture but have little effect on overall organ shape in Arabidopsis leaves.

J Exp Bot 2006 26;57(12):3019-31. Epub 2006 Jul 26.

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, E-03202 Elche, Spain.

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https://academic.oup.com/jxb/article-lookup/doi/10.1093/jxb/
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http://dx.doi.org/10.1093/jxb/erl063DOI Listing
December 2006

Both abscisic acid (ABA)-dependent and ABA-independent pathways govern the induction of NCED3, AAO3 and ABA1 in response to salt stress.

Plant Cell Environ 2006 Oct;29(10):2000-8

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Alicante, Spain.

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http://dx.doi.org/10.1111/j.1365-3040.2006.01576.xDOI Listing
October 2006

The SCABRA3 nuclear gene encodes the plastid RpoTp RNA polymerase, which is required for chloroplast biogenesis and mesophyll cell proliferation in Arabidopsis.

Plant Physiol 2006 Jul 12;141(3):942-56. Epub 2006 May 12.

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.

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http://dx.doi.org/10.1104/pp.106.080069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489898PMC
July 2006

Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain.

BMC Biochem 2006 Mar 27;7. Epub 2006 Mar 27.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1186/1471-2091-7-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435904PMC
March 2006

Regulated RNA processing in the control of Arabidopsis flowering.

Int J Dev Biol 2005 ;49(5-6):773-80

División de Genética and Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, Elche, Spain.

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http://dx.doi.org/10.1387/ijdb.051995vqDOI Listing
December 2005

Identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in Archaea.

J Biol Chem 2005 Aug 22;280(34):30367-75. Epub 2005 Jun 22.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M504533200DOI Listing
August 2005

Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase.

J Biol Chem 2005 Apr 1;280(14):14310-7. Epub 2005 Feb 1.

Departamento de Bioquímica y Biología Molecular and Biología Funcional, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M413222200DOI Listing
April 2005

Human polyserase-2, a novel enzyme with three tandem serine protease domains in a single polypeptide chain.

J Biol Chem 2005 Jan 9;280(3):1953-61. Epub 2004 Nov 9.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M409139200DOI Listing
January 2005

Identification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish.

J Biol Chem 2004 Jun 15;279(25):26627-34. Epub 2004 Apr 15.

Departamento de Bioquimica y Biologia Molecular and Morfologia y Biologia Celular, Facultad de Medicina, Instituto Universitario de Oncologia, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M401588200DOI Listing
June 2004

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

Biochem Biophys Res Commun 2004 Jan;314(1):54-62

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Spain.

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http://dx.doi.org/10.1016/j.bbrc.2003.12.050DOI Listing
January 2004

Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.

Proc Natl Acad Sci U S A 2003 Aug 28;100(16):9185-90. Epub 2003 Jul 28.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1073/pnas.1633392100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC170893PMC
August 2003

Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time.

EMBO J 2003 Jun;22(12):3142-52

Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, UK.

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http://dx.doi.org/10.1093/emboj/cdg305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162157PMC
June 2003

FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition.

Cell 2003 Jun;113(6):777-87

Department of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.

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http://dx.doi.org/10.1016/s0092-8674(03)00425-2DOI Listing
June 2003

Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.

J Biol Chem 2003 Apr 31;278(15):13382-9. Epub 2003 Jan 31.

Departamento de Bioquíimica y Biologíia Molecular, Facultad de Medicina, Instituto Universitario de Oncologíia, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://www.jbc.org/content/early/2003/01/31/jbc.M211900200.f
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http://www.jbc.org/cgi/doi/10.1074/jbc.M211900200
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http://dx.doi.org/10.1074/jbc.M211900200DOI Listing
April 2003

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.

J Biol Chem 2003 Feb 21;278(6):3671-8. Epub 2002 Nov 21.

Departamento de Bioquimíca y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Spain.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M208247200
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http://dx.doi.org/10.1074/jbc.M208247200DOI Listing
February 2003

Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.

J Biol Chem 2002 Oct 30;277(40):37637-46. Epub 2002 Jul 30.

Departamento de Bioquimica y Biologia Molecular, Instituto Universitario de Oncologia, Universidad de Oviedo, 33006 Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M203007200DOI Listing
October 2002

Genetic architecture of NaCl tolerance in Arabidopsis.

Plant Physiol 2002 Oct;130(2):951-63

División de Genética, , Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Alicante, Spain.

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http://dx.doi.org/10.1104/pp.006536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166621PMC
October 2002

Structural and enzymatic characterization of Drosophila Dm2-MMP, a membrane-bound matrix metalloproteinase with tissue-specific expression.

J Biol Chem 2002 Jun 19;277(26):23321-9. Epub 2002 Apr 19.

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006-Oviedo, Spain.

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http://dx.doi.org/10.1074/jbc.M200121200DOI Listing
June 2002

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

Gene 2002 Jan;283(1-2):49-62

Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006, Oviedo, Spain.

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http://dx.doi.org/10.1016/s0378-1119(01)00861-7DOI Listing
January 2002