Victor Nizet

Victor Nizet

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Victor Nizet

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Siglecs at the Host-Pathogen Interface.

Adv Exp Med Biol 2020 ;1204:197-214

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, and Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, 9500 Gilman Drive Mail Code 0760, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1007/978-981-15-1580-4_8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121523PMC
March 2020

Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages.

J Innate Immun 2019 2;11(1):86-98. Epub 2018 Nov 2.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, California, USA,

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https://www.karger.com/Article/FullText/493585
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http://dx.doi.org/10.1159/000493585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296884PMC
February 2020

Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program.

Genes Dev 2020 02 9;34(3-4):149-165. Epub 2020 Jan 9.

Division of Biological Sciences, Department of Molecular Biology, University of California at San Diego, La Jolla, California 92039, USA.

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http://dx.doi.org/10.1101/gad.333708.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000913PMC
February 2020

The Fungal Pathogen Promotes Bladder Colonization of Group B .

Front Cell Infect Microbiol 2019 10;9:437. Epub 2020 Jan 10.

Collaborative to Halt Antibiotic-Resistant Microbes, Department of Pediatrics, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966239PMC
January 2020

Siglec-14 Enhances NLRP3-Inflammasome Activation in Macrophages.

J Innate Immun 2019 Dec 5:1-11. Epub 2019 Dec 5.

Glycobiology Research and Training Center, UC San Diego, La Jolla, California, USA,

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http://dx.doi.org/10.1159/000504323DOI Listing
December 2019

A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus.

Nat Commun 2019 12 16;10(1):5726. Epub 2019 Dec 16.

Tata Institute for Genetics and Society, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0349, USA.

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http://dx.doi.org/10.1038/s41467-019-13649-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915771PMC
December 2019

Strain-Specific Metabolic Requirements Revealed by a Defined Minimal Medium for Systems Analyses of .

Appl Environ Microbiol 2019 11 16;85(21). Epub 2019 Oct 16.

Department of Bioengineering, University of California San Diego, La Jolla, California, USA

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http://dx.doi.org/10.1128/AEM.01773-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803309PMC
November 2019

Erythrocyte-Coated Nanoparticles Block Cytotoxic Effects of Group B β-Hemolysin/Cytolysin.

Front Pediatr 2019 1;7:410. Epub 2019 Nov 1.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fped.2019.00410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839037PMC
November 2019

Cefazolin and Ertapenem Salvage Therapy Rapidly Clears Persistent Methicillin-Susceptible Staphylococcus aureus Bacteremia.

Clin Infect Dis 2019 Nov 27. Epub 2019 Nov 27.

Collaborative to Halt Antibiotic-Resistant Microbes, Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla, California, USA.

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http://dx.doi.org/10.1093/cid/ciz995DOI Listing
November 2019

Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis.

Nat Commun 2019 10 11;10(1):4656. Epub 2019 Oct 11.

Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41467-019-12672-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789120PMC
October 2019

Detection of Epidemic Scarlet Fever Group A Streptococcus in Australia.

Clin Infect Dis 2019 Sep;69(7):1232-1234

Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia.

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http://dx.doi.org/10.1093/cid/ciz099DOI Listing
September 2019

Inflammasome inhibition blocks cardiac glycoside cell toxicity.

J Biol Chem 2019 08 12;294(34):12846-12854. Epub 2019 Jul 12.

Department of Pediatrics, University of California San Diego, La Jolla, California 92093

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http://dx.doi.org/10.1074/jbc.RA119.008330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709640PMC
August 2019

Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens.

EBioMedicine 2019 Aug 25;46:193-201. Epub 2019 Jul 25.

Department of Pediatrics, UC San Diego, La Jolla, CA 92093, USA; Collaborative to Halt Antibiotic-Resistant Microbes (CHARM), UC San Diego, La Jolla, CA 92093, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.07.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711115PMC
August 2019

IL-1β and IL-10 Host Responses in Patients with Staphylococcus aureus Bacteremia Determined by Antimicrobial Therapy.

Clin Infect Dis 2019 Aug 1. Epub 2019 Aug 1.

School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.

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http://dx.doi.org/10.1093/cid/ciz686DOI Listing
August 2019

PHLPP1 counter-regulates STAT1-mediated inflammatory signaling.

Elife 2019 08 13;8. Epub 2019 Aug 13.

Department of Pharmacology, University of California, San Diego, San Diego, United States.

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http://dx.doi.org/10.7554/eLife.48609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692130PMC
August 2019

Functional and Proteomic Analysis of Virulence Upon Loss of Its Native Cas9 Nuclease.

Front Microbiol 2019 22;10:1967. Epub 2019 Aug 22.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fmicb.2019.01967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714885PMC
August 2019

Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin.

Antimicrob Agents Chemother 2019 07 24;63(7). Epub 2019 Jun 24.

Center for Antimicrobial Resistance and Microbial Genomics (CARMiG), UTHealth McGovern Medical School, Houston, Texas, USA

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http://dx.doi.org/10.1128/AAC.02622-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591586PMC
July 2019

Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit.

Front Immunol 2018 9;9:679. Epub 2018 Apr 9.

Division of Cancer Biology and Inflammatory Disorder, CSIR-Indian Institute of Chemical Biology, Kolkata, India.

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http://dx.doi.org/10.3389/fimmu.2018.00679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900007PMC
June 2019

Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry.

Cell Chem Biol 2019 05 7;26(5):724-736.e7. Epub 2019 Mar 7.

Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525064PMC
May 2019

Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli.

J Innate Immun 2019 3;11(6):481-495. Epub 2019 May 3.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, California, USA,

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http://dx.doi.org/10.1159/000499342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758950PMC
May 2019

Docking simulation and antibiotic discovery targeting the MlaC protein in Gram-negative bacteria.

Chem Biol Drug Des 2019 04 19;93(4):647-652. Epub 2019 Feb 19.

Department of Pharmacology, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1111/cbdd.13462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737922PMC
April 2019

Dual actions of group B capsular sialic acid provide resistance to platelet-mediated antimicrobial killing.

Proc Natl Acad Sci U S A 2019 04 25;116(15):7465-7470. Epub 2019 Mar 25.

Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093;

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http://dx.doi.org/10.1073/pnas.1815572116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462088PMC
April 2019

Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion.

Front Pharmacol 2019 5;10:323. Epub 2019 Apr 5.

Department of Pharmacology, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fphar.2019.00323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460395PMC
April 2019

Impact of Anesthetics on Human Neutrophil Function.

Anesth Analg 2019 03;128(3):569-574

Department of Pediatrics, Division of Host-Microbe Systems & Therapeutics, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, San Diego, California.

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http://dx.doi.org/10.1213/ANE.0000000000003927DOI Listing
March 2019

Proton-pump inhibitors do not influence clinical outcomes in patients with bacteremia.

Therap Adv Gastroenterol 2019 21;12:1756284819834273. Epub 2019 Mar 21.

School of Medicine, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1177/1756284819834273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431768PMC
March 2019

Innate Immune Interactions between and Host Neutrophils.

Front Cell Infect Microbiol 2018 22;8. Epub 2018 Jan 22.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, San Diego, CA, United States.

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http://journal.frontiersin.org/article/10.3389/fcimb.2018.00
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http://dx.doi.org/10.3389/fcimb.2018.00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786542PMC
January 2019

Tamm-Horsfall Protein Protects the Urinary Tract against .

Infect Immun 2018 12 20;86(12). Epub 2018 Nov 20.

Department of Pediatrics, University of California, San Diego, La Jolla, California, USA

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http://iai.asm.org/lookup/doi/10.1128/IAI.00451-18
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http://dx.doi.org/10.1128/IAI.00451-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246913PMC
December 2018

Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection.

Toxins (Basel) 2018 12 17;10(12). Epub 2018 Dec 17.

Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.3390/toxins10120542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316385PMC
December 2018

The murine vaginal microbiota and its perturbation by the human pathogen group B Streptococcus.

BMC Microbiol 2018 11 26;18(1):197. Epub 2018 Nov 26.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, 9500 Gilman Dr, MC 0760, La Jolla, CA, 92093-0760, USA.

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https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12866-018-1341-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260558PMC
November 2018

Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance.

J Infect Dis 2018 10;218(10):1641-1652

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California-San Diego, La Jolla.

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http://dx.doi.org/10.1093/infdis/jiy341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173572PMC
October 2018

Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells.

Proc Natl Acad Sci U S A 2018 10 25;115(41):10410-10415. Epub 2018 Sep 25.

Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093

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http://dx.doi.org/10.1073/pnas.1804108115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187154PMC
October 2018

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis.

Cell Host Microbe 2018 10;24(4):500-513.e5

Center for Nanomedicine, University of California Santa Barbara, Santa Barbara, California 93106, USA; Sanford-Burham-Prebys Medical Discovery Institute, University of California Santa Barbara, Santa Barbara, California 93106, USA; Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California 93106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223661PMC
October 2018

Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors.

FEMS Microbiol Rev 2018 09;42(5):656-671

Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1093/femsre/fuy025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098222PMC
September 2018

Decontaminating surfaces with atomized disinfectants generated by a novel thickness-mode lithium niobate device.

Appl Microbiol Biotechnol 2018 Aug 26;102(15):6459-6467. Epub 2018 May 26.

Department of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1007/s00253-018-9088-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082180PMC
August 2018

Broad-Spectrum Neutralization of Pore-Forming Toxins with Human Erythrocyte Membrane-Coated Nanosponges.

Adv Healthc Mater 2018 07 13;7(13):e1701366. Epub 2018 Feb 13.

Department of NanoEngineering and Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1002/adhm.201701366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041168PMC
July 2018

The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis.

Microbiol Mol Biol Rev 2018 06 7;82(1). Epub 2018 Feb 7.

University of California, San Diego, Department of Pediatrics, Division of Host-Microbe Systems and Therapeutics, San Diego, California, USA.

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http://dx.doi.org/10.1128/MMBR.00057-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813886PMC
June 2018

Human evolutionary loss of epithelial Neu5Gc expression and species-specific susceptibility to cholera.

PLoS Pathog 2018 06 18;14(6):e1007133. Epub 2018 Jun 18.

Glycobiology Research and Training Center (GRTC), Center for Academic Research and Training in Anthropogeny (CARTA), Departments of Medicine and Cellular & Molecular Medicine, University of California San Diego, La Jolla, CA, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023241PMC
June 2018

Stabilization of Hypoxia-Inducible Factor-1 Alpha Augments the Therapeutic Capacity of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Pneumonia.

Front Med (Lausanne) 2018 4;5:131. Epub 2018 May 4.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA, United States.

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http://journal.frontiersin.org/article/10.3389/fmed.2018.001
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http://dx.doi.org/10.3389/fmed.2018.00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945808PMC
May 2018

Telavancin for refractory MRSA bacteraemia in intermittent haemodialysis recipients.

J Antimicrob Chemother 2018 03;73(3):764-767

Division of Host-Microbe Systems & Therapeutics, Center for Immunity, Infection & Inflammation, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA, USA.

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http://dx.doi.org/10.1093/jac/dkx437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890690PMC
March 2018

Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies.

Int J Antimicrob Agents 2018 Mar 11;51(3):468-478. Epub 2018 Jan 11.

Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.ijantimicag.2017.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860678PMC
March 2018

Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster.

J Antibiot (Tokyo) 2018 02 29;71(2):333-338. Epub 2017 Nov 29.

Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/ja.2017.146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960985PMC
February 2018

Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance.

Sci Rep 2018 02 2;8(1):2215. Epub 2018 Feb 2.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-018-20661-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797083PMC
February 2018

Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches.

Front Pediatr 2018 22;6:27. Epub 2018 Feb 22.

Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, CA, United States.

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http://dx.doi.org/10.3389/fped.2018.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827363PMC
February 2018

Modeling neuro-immune interactions during Zika virus infection.

Hum Mol Genet 2018 01;27(1):41-52

Department of Pediatrics/Rady Children's Hospital San Diego, University of California San Diego, La Jolla, CA 92093-0695, USA.

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http://dx.doi.org/10.1093/hmg/ddx382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886060PMC
January 2018

Group A Streptococcus encounters with host macrophages.

Future Microbiol 2018 01 11;13:119-134. Epub 2017 Dec 11.

Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.2217/fmb-2017-0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771463PMC
January 2018

Self-Assembled Colloidal Gel Using Cell Membrane-Coated Nanosponges as Building Blocks.

ACS Nano 2017 12 10;11(12):11923-11930. Epub 2017 Nov 10.

Department of Nanoengineering, ‡Moores Cancer Center, §Department of Pediatrics, ∥Skaggs School of Pharmacy and Pharmaceutical Sciences, ⊥Department of Bioengineering, and #Sanford Consortium for Regenerative Medicine, University of California San Diego , La Jolla, California 92093, United States.

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http://pubs.acs.org/doi/10.1021/acsnano.7b06968
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http://dx.doi.org/10.1021/acsnano.7b06968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336496PMC
December 2017

Interaction of Antibiotics with Innate Host Defense Factors against Serotype Newport.

mSphere 2017 Nov-Dec;2(6). Epub 2017 Dec 6.

University of California San Diego School of Medicine, La Jolla, California, USA.

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http://dx.doi.org/10.1128/mSphere.00410-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717323PMC
December 2017

Recurrent infection progressively disables host protection against intestinal inflammation.

Science 2017 12;358(6370)

Center for Nanomedicine, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.

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http://dx.doi.org/10.1126/science.aao5610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824721PMC
December 2017

Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract.

Immunol Cell Biol 2017 11 22;95(10):960-965. Epub 2017 Aug 22.

Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, UC San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/icb.2017.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698129PMC
November 2017

Group A streptococcal M protein activates the NLRP3 inflammasome.

Nat Microbiol 2017 Oct 7;2(10):1425-1434. Epub 2017 Aug 7.

Department of Pediatrics, University of California, San Diego, La Jolla, CA, 92093, USA.

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http://dx.doi.org/10.1038/s41564-017-0005-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750061PMC
October 2017

Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions.

Nat Commun 2017 09 7;8(1):477. Epub 2017 Sep 7.

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

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http://dx.doi.org/10.1038/s41467-017-00569-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589908PMC
September 2017

Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport.

PLoS Pathog 2017 Sep 25;13(9):e1006603. Epub 2017 Sep 25.

Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612732PMC
September 2017

The Accidental Orthodoxy of Drs. Mueller and Hinton.

Authors:
Victor Nizet

EBioMedicine 2017 08 4;22:26-27. Epub 2017 Jul 4.

Division of Host Microbe Systems & Therapeutics, Department of Pediatrics, UC San Diego School of Medicine, La Jolla, CA, USA; Skaggs School of Pharmacy & Pharmaceutical Sciences, UC San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552209PMC
August 2017

A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin -Mediated Virulence Phenotypes of Invasive Group A .

Front Pharmacol 2017 18;8:477. Epub 2017 Jul 18.

Biomedical Sciences Graduate Program, University of California, San Diego, La JollaCA, United States.

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http://dx.doi.org/10.3389/fphar.2017.00477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513932PMC
July 2017

Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs.

Trends Pharmacol Sci 2017 05 8;38(5):473-488. Epub 2017 Mar 8.

Department of Pediatrics, Division of Host-Microbe Systems and Therapeutics, University of California San Diego, La Jolla, CA 92093, USA; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA 92093, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093, USA; Rady Children's Hospital, San Diego, CA 92123, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750058PMC
May 2017

Evidence To Support Continuation of Statin Therapy in Patients with Staphylococcus aureus Bacteremia.

Antimicrob Agents Chemother 2017 03 23;61(3). Epub 2017 Feb 23.

Veterans Affairs Medical Center, Infectious Diseases Research Program and Center of Innovation in Long Term Services and Supports, Providence, Rhode Island, USA

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http://dx.doi.org/10.1128/AAC.02228-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328562PMC
March 2017

Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen.

EMBO J 2017 03 18;36(6):751-760. Epub 2017 Jan 18.

Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA

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http://dx.doi.org/10.15252/embj.201695581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350563PMC
March 2017

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones.

Sci Rep 2017 02 21;7:43039. Epub 2017 Feb 21.

Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America.

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http://dx.doi.org/10.1038/srep43039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318940PMC
February 2017

Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil.

Front Pediatr 2017 28;5:23. Epub 2017 Feb 28.

Division of Host-Microbe Systems and Therapeutics, UCSD, La Jolla, CA, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fped.2017.00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329040PMC
February 2017

SAMP-ending down sepsis.

Ann Transl Med 2016 Dec;4(24):509

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; ; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA; ; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.21037/atm.2016.11.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233519PMC
December 2016