Publications by authors named "Victor E Ortega"

54Publications

Step-Up Therapy in Black Patients with Asthma. Reply.

N Engl J Med 2020 01;382(4):391-392

Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1056/NEJMc1915819DOI Listing
January 2020

Immune and Cytokine Dysfunction in Cystic Fibrosis.

Am J Respir Cell Mol Biol 2019 11;61(5):656-658

Wake Forest School of MedicineWinston-Salem, North Carolinaand.

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http://dx.doi.org/10.1165/rcmb.2018-0361LEDOI Listing
November 2019

Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.

N Engl J Med 2019 09;381(13):1227-1239

From National Jewish Health (M.E.W., R.C., J.T.O.), Denver, and University of Colorado School of Medicine (M.E.W., S.J.S., R.C., F.H., J.T.O.) and Children's Hospital Colorado (S.J.S.), Aurora - all in Colorado; Wake Forest School of Medicine (V.E.O., W.C.M., S.P.P.), Winston-Salem, North Carolina Clinical Research (C.F.L.), Raleigh, and Duke University Medical Center (N.L., L.Q.), Durham - all in North Carolina; Ann and Robert H. Lurie Children's Hospital of Chicago (J.A.P., R.G.R.), University of Illinois at Chicago (J.A.K., H.K.), Rush University Medical Center (J.M.), University of Chicago (E.N., J.S., S. White), and Northwestern University Feinberg School of Medicine (L.J.S.) - all in Chicago; Penn State University (V.C., S.J.K., D.M.), Hershey, and Allegheny General Hospital (D.G.) and University of Pittsburgh Medical Center (S. Wenzel), Pittsburgh - all in Pennsylvania; Nemours Children's Health System, Jacksonville (J.J.L., K.V.B., J.L.), and University of South Florida Morsani College of Medicine, Tampa (J.-C.C.) - both in Florida; University of Arizona Health Sciences, Tucson (E.R.B., M.K., F.M., D.A.M.); Washington University School of Medicine, St. Louis (L.B.B., A.B., M.C.); University of California, San Francisco (UCSF), San Francisco (M.B., M.D.C., S.C.L., D.L.) and UCSF Benioff Children's Hospital, Oakland (M.B., D.L.) - both in California; Brigham and Women's Hospital and Harvard Medical School (J.-C.C., N.G., E.I.) and Boston Children's Hospital (W.P., W.S.) - all in Boston; University Hospitals Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland (J.F.C., K.R.); University of Wisconsin-Madison, Madison (L.D., D.J.J., R.F.L., C.A.S.) and Aurora Sinai Medical Center, Milwaukee (L.S.-V.) - both in Wisconsin; Columbia University Irving Medical Center, New York, (E.D.); Emory University, Atlanta (A.M.F.); and University of New Mexico, Albuquerque (H.R.).

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http://dx.doi.org/10.1056/NEJMoa1905560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026584PMC
September 2019

Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 Sep 4;10(1):4082. Epub 2019 Sep 4.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-12158-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726619PMC
September 2019

The discovery of novel mechanisms for lymphangioleiomyomatosis pathogenesis through GWAS: a rarity in rare respiratory disorders.

Eur Respir J 2019 Jun 27;53(6). Epub 2019 Jun 27.

Dept of Internal Medicine, Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

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http://dx.doi.org/10.1183/13993003.00863-2019DOI Listing
June 2019

Resequencing to Fine Map Known Idiopathic Pulmonary Fibrosis Risk Genes. Homing in on Causal Variants.

Am J Respir Crit Care Med 2019 Jul;200(2):125-127

2 Department of Internal Medicine Center for Precision Medicine Winston-Salem, North Carolina.

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http://dx.doi.org/10.1164/rccm.201905-0925EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635787PMC
July 2019

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 02 20;10(1):880. Epub 2019 Feb 20.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-08469-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382865PMC
February 2019

Genome-wide association study of lung function and clinical implication in heavy smokers.

BMC Med Genet 2018 08 1;19(1):134. Epub 2018 Aug 1.

Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, BioScience Research Lab, Room 253, 1230 N. Cherry Avenue, PO Box 210242, Tucson, AZ, 85721, USA.

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http://dx.doi.org/10.1186/s12881-018-0656-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090900PMC
August 2018

Picking the Right Fruit: Intersecting Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Discoveries with Epigenetics.

Authors:
Victor E Ortega

Am J Respir Crit Care Med 2018 05;197(10):1237-1239

1 Department of Internal Medicine and.

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http://dx.doi.org/10.1164/rccm.201801-0084EDDOI Listing
May 2018

Income is an independent risk factor for worse asthma outcomes.

J Allergy Clin Immunol 2018 02 20;141(2):754-760.e3. Epub 2017 May 20.

Department of Medicine, Brigham and Women's Hospital, Boston, Mass; the Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.04.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696111PMC
February 2018

Making progress toward understanding the genetic architecture of asthma in the most affected US ethnic group.

Eur Respir J 2017 05 1;49(5). Epub 2017 May 1.

Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1183/13993003.00329-2017DOI Listing
May 2017

Understanding at-risk subgroups for lung function impairment in life-long nonsmokers with α-antitrypsin deficiency.

Eur Respir J 2017 03 29;49(3). Epub 2017 Mar 29.

Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1183/13993003.00114-2017DOI Listing
March 2017

On a Collision Course: The Electronic Medical Record and Genetic Studies of Asthma.

Am J Respir Crit Care Med 2017 02;195(4):412-414

2 Lung Biology Center University of California San Francisco San Francisco, California.

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http://dx.doi.org/10.1164/rccm.201609-1941EDDOI Listing
February 2017

The Advent of High-Throughput Sequencing Studies of Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2016 06;193(12):1323-4

2 Children's Hospital of Pittsburgh of UPMC University of Pittsburgh Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201601-0074EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910894PMC
June 2016

The Effect of Ancestry and Genetic Variation on Lung Function Predictions: What Is "Normal" Lung Function in Diverse Human Populations?

Curr Allergy Asthma Rep 2015 Apr;15(4):16

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157, USA,

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http://dx.doi.org/10.1007/s11882-015-0516-2DOI Listing
April 2015

Predictive genetic profiles for β-agonist therapy in asthma. A future under construction.

Authors:
Victor E Ortega

Am J Respir Crit Care Med 2015 Mar;191(5):494-6

1 Center for Genomics and Personalized Medicine Research Wake Forest School of Medicine Winston-Salem, North Carolina.

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http://dx.doi.org/10.1164/rccm.201501-0055EDDOI Listing
March 2015

Asthma pharmacogenetics and the development of genetic profiles for personalized medicine.

Pharmgenomics Pers Med 2015 16;8:9-22. Epub 2015 Jan 16.

Center for Genomics and Personalized Medicine Research, Pulmonary Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://www.dovepress.com/asthma-pharmacogenetics-and-the-dev
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http://dx.doi.org/10.2147/PGPM.S52846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325626PMC
February 2015

Implications of population structure and ancestry on asthma genetic studies.

Curr Opin Allergy Clin Immunol 2014 Oct;14(5):381-9

Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1097/ACI.0000000000000102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278361PMC
October 2014

Pharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicine.

J Allergy Clin Immunol 2014 Jan;133(1):16-26

Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, NC. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933289PMC
January 2014

Pharmacogenetics and the development of personalized approaches for combination therapy in asthma.

Curr Allergy Asthma Rep 2013 Oct;13(5):443-52

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Medical Center Blvd, Winston- Salem, NC, 27157, USA.

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http://dx.doi.org/10.1007/s11882-013-0372-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878163PMC
October 2013

Asthma pharmacogenetics: responding to the call for a personalized approach.

Curr Opin Allergy Clin Immunol 2013 Aug;13(4):399-409

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1097/ACI.0b013e3283630c19DOI Listing
August 2013

Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects.

J Allergy Clin Immunol 2013 Jul 21;132(1):72-80. Epub 2013 May 21.

Center for Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.jaci.2013.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704048PMC
July 2013

Beta-2 adrenergic agonists: focus on safety and benefits versus risks.

Curr Opin Pharmacol 2010 Jun 6;10(3):246-53. Epub 2010 May 6.

Wake Forest University Health Sciences, Center for Genomics and Personalized Medicine Research, Medical Center Boulevard, Winston-Salem, NC, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S14714892100004
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http://dx.doi.org/10.1016/j.coph.2010.04.009DOI Listing
June 2010

Pharmacogenetics of the beta 2-adrenergic receptor gene.

Immunol Allergy Clin North Am 2007 Nov;27(4):665-84; vii

Center for Human Genomics, Section of Pulmonary, Critical Care, Allergy, and Immunologic Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S08898561070008
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http://dx.doi.org/10.1016/j.iac.2007.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736101PMC
November 2007

A Roadmap to functional genomics.

Physiol Genomics 2007 Jun 27;30(1):82-8. Epub 2007 Feb 27.

Department of Internal Medicine and the Center for Human Genomics, Wake Forest University Health Sciences, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00010.2007DOI Listing
June 2007