Vicente Planelles

Vicente Planelles

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Vicente Planelles

Vicente Planelles

Publications by authors named "Vicente Planelles"

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Tyrosine Kinase Inhibition: a New Perspective in the Fight against HIV.

Curr HIV/AIDS Rep 2019 Oct;16(5):414-422

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo km2, 28220, Madrid, Spain.

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http://dx.doi.org/10.1007/s11904-019-00462-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814579PMC
October 2019

Transcriptional Circuit Fragility Influences HIV Proviral Fate.

Cell Rep 2019 04;27(1):154-171.e9

Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461408PMC
April 2019

Sex Influences SAMHD1 Activity and Susceptibility to Human Immunodeficiency Virus-1 in Primary Human Macrophages.

J Infect Dis 2019 02;219(5):777-785

Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine.

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http://dx.doi.org/10.1093/infdis/jiy583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376916PMC
February 2019

Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal.

Antimicrob Agents Chemother 2018 11 24;62(11). Epub 2018 Oct 24.

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1128/AAC.01361-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201092PMC
November 2018

Dual TLR2 and TLR7 agonists as HIV latency-reversing agents.

JCI Insight 2018 10 4;3(19). Epub 2018 Oct 4.

Department of Microbiology, Immunology, and Tropical Medicine, George Washington University, Washington, DC, USA.

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http://dx.doi.org/10.1172/jci.insight.122673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237480PMC
October 2018

Influence of Biological Sex, Age, and HIV Status in an In Vitro Primary Cell Model of HIV Latency Using a CXCR4 Tropic Virus.

AIDS Res Hum Retroviruses 2018 09 10;34(9):769-777. Epub 2018 Aug 10.

1 Department of Microbiology, Immunology, and Tropical Medicine, School of Medicine and Health Sciences, George Washington University , Washington, District of Columbia.

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https://www.liebertpub.com/doi/10.1089/aid.2018.0098
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http://dx.doi.org/10.1089/AID.2018.0098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152854PMC
September 2018

Novel Latency Reversal Agents for HIV-1 Cure.

Annu Rev Med 2018 01 3;69:421-436. Epub 2017 Nov 3.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84112; email:

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http://dx.doi.org/10.1146/annurev-med-052716-031710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892446PMC
January 2018

Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitro.

PLoS One 2017 26;12(9):e0185162. Epub 2017 Sep 26.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185162PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614573PMC
October 2017

When DNA damage is acceptable.

Cell Cycle 2017 06 19;16(11):1020-1021. Epub 2017 May 19.

a Division of Microbiology and Immunology, Department of Pathology , University of Utah , Salt Lake City , UT , USA.

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http://dx.doi.org/10.1080/15384101.2017.1324125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499848PMC
June 2017

Macrophage Cell Coinfected with HIV-1 and H37Ra.

AIDS Res Hum Retroviruses 2016 12 16;32(12):1171-1172. Epub 2016 Jun 16.

1 Department of Pharmacology and Toxicology, University of Utah , Salt Lake City, Utah.

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http://dx.doi.org/10.1089/aid.2016.0067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175448PMC
December 2016

Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo.

Retrovirology 2016 Dec 20;13(1):88. Epub 2016 Dec 20.

Department of Pathology, University of Utah School of Medicine, Emma Eccles Jones Medical Research Building Room 2520, 15 North Medical Drive East, Salt Lake City, UT, 84112, USA.

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http://dx.doi.org/10.1186/s12977-016-0319-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175306PMC
December 2016

HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function.

Front Immunol 2016 21;7:356. Epub 2016 Sep 21.

UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.3389/fimmu.2016.00356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030263PMC
September 2016

Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex.

Mol Ther 2016 Mar 19;24(3):488-98. Epub 2015 Nov 19.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1038/mt.2015.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786915PMC
March 2016

Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus.

AIDS Res Hum Retroviruses 2016 02 14;32(2):187-93. Epub 2015 Jul 14.

1 Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine , Salt Lake City, Utah.

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http://dx.doi.org/10.1089/aid.2015.0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761834PMC
February 2016

HIV-1 Eradication: Early Trials (and Tribulations).

Trends Mol Med 2016 Jan 12;22(1):10-27. Epub 2015 Dec 12.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889129PMC
January 2016

Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients.

Antimicrob Agents Chemother 2015 Oct 13;59(10):5984-91. Epub 2015 Jul 13.

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA

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http://dx.doi.org/10.1128/AAC.01077-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576101PMC
October 2015

An Ounce of Tat Prevention Is Worth a Pound of Functional Cure.

mBio 2015 Aug 18;6(4). Epub 2015 Aug 18.

Division of Microbiology & Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA

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http://dx.doi.org/10.1128/mBio.01269-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542193PMC
August 2015

HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins.

Retrovirology 2015 Jul 28;12:65. Epub 2015 Jul 28.

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, 84112, USA.

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http://dx.doi.org/10.1186/s12977-015-0192-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517359PMC
July 2015

Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.

Virology 2015 Mar 22;477:10-17. Epub 2015 Jan 22.

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East #2100, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.12.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455942PMC
March 2015

Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx.

Virology 2015 Feb 11;476:19-25. Epub 2014 Dec 11.

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East #2100, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.virol.2014.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323848PMC
February 2015

Sulfonation pathway inhibitors block reactivation of latent HIV-1.

Virology 2014 Dec 11;471-473:1-12. Epub 2014 Oct 11.

Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Rd., La Jolla, CA 92037, USA; Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392775PMC
December 2014

Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro.

Antimicrob Agents Chemother 2014 13;58(4):1977-86. Epub 2014 Jan 13.

Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1128/AAC.02496-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023721PMC
November 2014

An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription.

Mol Ther 2014 Jun 28;22(6):1164-1175. Epub 2014 Feb 28.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA; School of Biotechnology and Biomedical Sciences, University of New South Wales, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1038/mt.2014.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048891PMC
June 2014

Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells.

Cell Rep 2014 Jun 5;7(6):2019-30. Epub 2014 Jun 5.

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080720PMC
June 2014

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation.

Retrovirology 2013 Oct 24;10:119. Epub 2013 Oct 24.

Division of Microbiology and Immunology, Department of Pathology, University Of Utah School of Medicine, Emma Eccles Jones Medical Research Building, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1186/1742-4690-10-119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826617PMC
October 2013

Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells.

PLoS One 2012 3;7(5):e35385. Epub 2012 May 3.

Center for Retrovirus Research, Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343049PMC
January 2013

Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.

J Virol 2013 Jan 14;87(2):1211-20. Epub 2012 Nov 14.

Department of Molecular Microbiology and Virology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1128/JVI.02413-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554045PMC
January 2013

SAMHD1 Joins the red Queen's court.

Cell Host Microbe 2012 Feb;11(2):103-5

Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Emma Eccles Jones Building, 15 North Medical Drive East #2100, Room 2520, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.chom.2012.02.001DOI Listing
February 2012

Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs.

Curr HIV Res 2011 Dec;9(8):568-78

Department of Pathology, University of Utah, Salt Lake City, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771330PMC
http://dx.doi.org/10.2174/157016211798998826DOI Listing
December 2011

Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells.

PLoS Pathog 2011 Oct 6;7(10):e1002288. Epub 2011 Oct 6.

Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188522PMC
October 2011

Restricted access to myeloid cells explained.

Viruses 2011 09 5;3(9):1624-33. Epub 2011 Sep 5.

Division of Microbiology and Immunology, Department of Pathology, School of Medicine, University of Utah, Emma Eccles Jones Building, 15 North Medical Drive East 2100, Room 2520, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.3390/v3091624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187686PMC
September 2011

Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells.

Methods 2011 Jan 21;53(1):54-61. Epub 2010 Oct 21.

Department of Pathology, University of Utah, 15 North Medical Dr East #2100, Room 2520, Salt Lake City, UT 84112, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10462023100025
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http://dx.doi.org/10.1016/j.ymeth.2010.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031099PMC
January 2011

Roles of Vpr and Vpx in modulating the virus-host cell relationship.

Mol Aspects Med 2010 Oct 15;31(5):398-406. Epub 2010 Jun 15.

Division of Cell Biology and Immunology, Department of Pathology, University of Utah School of Medicine, #2100 - Room 2520, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.mam.2010.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967654PMC
October 2010

Vpr and its interactions with cellular proteins.

Curr Top Microbiol Immunol 2009 ;339:177-200

Division of Cell Biology and Immunology, Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East #2100-Room 2520, Salt Lake City, Utah 84112, USA.

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http://link.springer.com/10.1007/978-3-642-02175-6_9
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http://dx.doi.org/10.1007/978-3-642-02175-6_9DOI Listing
April 2010

HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.

PLoS Pathog 2009 Oct 2;5(10):e1000613. Epub 2009 Oct 2.

Department of Microbiology and Immunology, State University of New York, Upstate Medical University, Syracuse, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747015PMC
October 2009

Epigenetic regulation of HIV-1 latency by cytosine methylation.

PLoS Pathog 2009 Jun 26;5(6):e1000495. Epub 2009 Jun 26.

Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695767PMC
June 2009

Characterizing the anti-HIV activity of papuamide A.

Mar Drugs 2008 8;6(4):528-49. Epub 2008 Oct 8.

University of Utah, Department of Pharmacology and Toxicology, 30 S. 2000 E. Rm.201, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.3390/md20080027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630844PMC
March 2009

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells.

Blood 2009 Jan 10;113(1):58-65. Epub 2008 Oct 10.

Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East #2100, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1182/blood-2008-07-168393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614643PMC
January 2009

Human immunodeficiency virus type 1 Vif induces cell cycle delay via recruitment of the same E3 ubiquitin ligase complex that targets APOBEC3 proteins for degradation.

J Virol 2008 Sep 2;82(18):9265-72. Epub 2008 Jul 2.

Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East no. 2100, Room 2520, Salt Lake City, Utah 84112, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00377-08
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http://dx.doi.org/10.1128/JVI.00377-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546900PMC
September 2008

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.

Exp Mol Pathol 2008 Aug 25;85(1):2-10. Epub 2008 Apr 25.

Center for the Study of Aging and Human Development, Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.yexmp.2008.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610539PMC
August 2008

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.

J Virol 2008 Feb 12;82(3):1066-72. Epub 2007 Sep 12.

Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East #2100, Room 2520, Salt Lake City, UT 84112, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01628-07
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http://dx.doi.org/10.1128/JVI.01628-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224437PMC
February 2008

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.

Retrovirology 2008 Jan 31;5:11. Epub 2008 Jan 31.

Department of Microbiology and Immunology, School of Medicine, University of Rochester Medical Center 601 Elmwood Avenue Box 672 Rochester, New York 14742 USA.

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http://dx.doi.org/10.1186/1742-4690-5-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265748PMC
January 2008

Host factors influencing susceptibility to HIV infection and AIDS progression.

Retrovirology 2007 Jul 25;4:52. Epub 2007 Jul 25.

La Jolla Institute for Molecular Medicine, 4570 Executive Drive, Suite 100, San Diego, California 92121, USA.

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http://dx.doi.org/10.1186/1742-4690-4-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978541PMC
July 2007

HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system.

Virol J 2007 Jun 8;4:57. Epub 2007 Jun 8.

Division of Cell Biology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.

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http://virologyj.biomedcentral.com/articles/10.1186/1743-422
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http://dx.doi.org/10.1186/1743-422X-4-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904188PMC
June 2007

Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.

J Mol Biol 2007 Feb 10;366(1):67-81. Epub 2006 Nov 10.

Department of Microbiology and Immunology, School of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 672, Rochester, NY 14742, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360601540
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http://dx.doi.org/10.1016/j.jmb.2006.11.011DOI Listing
February 2007

HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

PLoS Pathog 2006 Dec;2(12):e127

Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.0020127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665652PMC
December 2006

CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection.

Virology 2006 Sep 14;352(2):268-84. Epub 2006 Jun 14.

Department of Molecular Biology and Biochemistry, Center for Immunology and Center for Virus Research, University of California, Irvine, CA 92697-3900, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220600297
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http://dx.doi.org/10.1016/j.virol.2006.04.037DOI Listing
September 2006

Efficiency of lentiviral transduction during development in normal and rd mice.

Mol Vis 2006 Jul 11;12:756-67. Epub 2006 Jul 11.

Eye Research Institute, Oakland University, Rochester, MI, USA.

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July 2006

Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 Vpr.

J Virol 2006 Apr;80(8):3694-700

Division of Cellular Biology and Immunology, Department of Pathology, University of Utah School of Medicine, 30 N 1900 East, SOM 5C210, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1128/JVI.80.8.3694-3700.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440437PMC
April 2006

Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines.

Clin Cancer Res 2006 Jan;12(1):250-6

Department of Radiation Oncology, University of Utah School of Medicine and Huntsman Cancer Hospital, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-1084DOI Listing
January 2006

Current status of gene therapy strategies to treat HIV/AIDS.

Mol Ther 2005 Jun;11(6):823-42

Department of Pathology, Jefferson Medical College, 1020 Locust Street, Room 251, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.ymthe.2005.01.020DOI Listing
June 2005

The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration.

J Virol 2005 Feb;79(3):1389-96

Division of Cellular Biology and Immunology, Department of Pathology, University of Utah School of Medicine, 30 N 1900 East, SOM 5C210, Salt Lake City, UT 84132, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.79.3.1389-1396.2005
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http://dx.doi.org/10.1128/JVI.79.3.1389-1396.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544104PMC
February 2005

The role of Vpr in HIV-1 pathogenesis.

Curr HIV Res 2005 Jan;3(1):43-51

Division of Cellular Biology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.2174/1570162052772988DOI Listing
January 2005

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase.

J Biol Chem 2004 Dec 26;279(49):51545-53. Epub 2004 Sep 26.

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M408573200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351161PMC
December 2004

Inhibition of HIV type 1 replication using lentiviral-mediated delivery of mutant tRNA(Lys3)A58U.

AIDS Res Hum Retroviruses 2004 Dec;20(12):1324-34

Department of Biochemistry, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

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http://www.liebertpub.com/doi/10.1089/aid.2004.20.1324
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http://dx.doi.org/10.1089/aid.2004.20.1324DOI Listing
December 2004

Identification of a preferred region for recombination and mutation in HIV-1 gag.

Virology 2004 Sep;326(2):262-79

Department of Medicine, University of Rochester School of Medicine and Dentistry, NY, USA.

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http://dx.doi.org/10.1016/j.virol.2004.02.033DOI Listing
September 2004

Hybrid lentivirus vectors.

Methods Mol Biol 2003 ;229:273-84

School of Medicine, University of Utah, Salt Lake City, USA.

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http://dx.doi.org/10.1385/1-59259-393-3:273DOI Listing
October 2003

Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA.

AIDS Res Hum Retroviruses 2003 Aug;19(8):699-706

Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

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http://dx.doi.org/10.1089/088922203322280928DOI Listing
August 2003

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

J Biol Chem 2003 Jul 8;278(28):25879-86. Epub 2003 May 8.

Department of Microbiology and Immunology, University of Rochester Cancer Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M303948200DOI Listing
July 2003

Vectors derived from the human immunodeficiency virus, HIV-1.

Front Biosci 2003 May 1;8:d491-510. Epub 2003 May 1.

Department of Microbiology and Immunology, State University of New York, Upstate Medical University, 750 East Adams Street, Syracuse, NY, USA.

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http://dx.doi.org/10.2741/939DOI Listing
May 2003

A multigene lentiviral vector system based on differential splicing.

Methods Mol Med 2003 ;76:433-48

Departments of Microbiology & Immunology and Medicine, University of Rochester Cancer Center, Rochester, NY, USA.

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http://dx.doi.org/10.1385/1-59259-304-6:433DOI Listing
April 2003

Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis.

Mol Ther 2002 May;5(5 Pt 1):547-54

Center for Cardiovascular Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1006/mthe.2002.0590DOI Listing
May 2002