Publications by authors named "Vibhor Gupta"

15Publications

In silico screening, genotyping, molecular dynamics simulation and activity studies of SNPs in pyruvate kinase M2.

PLoS One 2015 13;10(3):e0120469. Epub 2015 Mar 13.

National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India; School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120469PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359060PMC
February 2016

Pyruvate kinase M2 and cancer: an updated assessment.

FEBS Lett 2014 Aug 18;588(16):2685-92. Epub 2014 Apr 18.

National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.04.011DOI Listing
August 2014

Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner.

J Biol Chem 2014 Mar 3;289(12):8098-105. Epub 2014 Feb 3.

From the National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Mehrauli Road, New Delhi, 110067 India.

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http://dx.doi.org/10.1074/jbc.M113.515742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961641PMC
March 2014

A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses.

Cell Rep 2013 Oct 26;5(1):180-93. Epub 2013 Sep 26.

Department of Animal Biology and Mari Lowe Comparative Oncology Center, School of Veterinary Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.08.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813903PMC
October 2013

Interplay between epigenetics & cancer metabolism.

Curr Pharm Des 2014 ;20(11):1706-14

National Center of Applied Human Genetics, School of Life Science, Jawaharlal Nehru University, New Delhi-110067, India.

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http://dx.doi.org/10.2174/13816128113199990536DOI Listing
December 2014

Pyruvate kinase M2: regulatory circuits and potential for therapeutic intervention.

Curr Pharm Des 2014 ;20(15):2595-606

Nal Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.

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http://dx.doi.org/10.2174/13816128113199990484DOI Listing
February 2015

RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.

Sci Signal 2012 Dec 4;5(253):ra88. Epub 2012 Dec 4.

Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/scisignal.2003485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131685PMC
December 2012

Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors.

PLoS One 2012 30;7(3):e33453. Epub 2012 Mar 30.

Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033453PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316569PMC
August 2012

Human pyruvate kinase M2: a multifunctional protein.

Protein Sci 2010 Nov;19(11):2031-44

National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

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http://dx.doi.org/10.1002/pro.505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005776PMC
November 2010

Dominant negative mutations affect oligomerization of human pyruvate kinase M2 isozyme and promote cellular growth and polyploidy.

J Biol Chem 2010 May 19;285(22):16864-73. Epub 2010 Mar 19.

National Centre of Applied Human Genetics, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.065029
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http://dx.doi.org/10.1074/jbc.M109.065029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878009PMC
May 2010

Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes.

PLoS Biol 2007 Dec;5(12):e326

Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom.

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http://dx.plos.org/10.1371/journal.pbio.0050326
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http://dx.doi.org/10.1371/journal.pbio.0050326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121114PMC
December 2007