Vesa M Olkkonen

Vesa M Olkkonen

UNVERIFIED PROFILE

Are you Vesa M Olkkonen?   Register this Author

Register author
Vesa M Olkkonen

Vesa M Olkkonen

Publications by authors named "Vesa M Olkkonen"

Are you Vesa M Olkkonen?   Register this Author

100Publications

1511Reads

13Profile Views

Bis(monoacylglycero)phosphate regulates oxysterol binding protein-related protein 11 dependent sterol trafficking.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 Sep 25;1864(9):1247-1257. Epub 2019 May 25.

Inserm, U1060, CarMeN Laboratory, Villeurbanne, France; INSA-Lyon, Villeurbanne, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2019.05.011DOI Listing
September 2019

Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State.

Arterioscler Thromb Vasc Biol 2019 Apr;39(4):665-674

Department of Internal Medicine and Medical Specialties (I.M., A.D.C., L.D., M.A.), Sapienza University of Rome, Italy.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/ATVBAHA.118.312021
Publisher Site
http://dx.doi.org/10.1161/ATVBAHA.118.312021DOI Listing
April 2019

ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol.

Biochimie 2019 Mar 24;158:90-101. Epub 2018 Dec 24.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290, Helsinki, Finland; Department of Anatomy, Faculty of Medicine, FI-00014, University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03009084183035
Publisher Site
http://dx.doi.org/10.1016/j.biochi.2018.12.013DOI Listing
March 2019

OSBP-related protein 2 (ORP2): Unraveling its functions in cellular lipid/carbohydrate metabolism, signaling and F-actin regulation.

J Steroid Biochem Mol Biol 2019 Feb 2. Epub 2019 Feb 2.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290, Helsinki, Finland; Department of Anatomy, Faculty of Medicine, FI-00014, University of Helsinki, Finland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09600760183076
Publisher Site
http://dx.doi.org/10.1016/j.jsbmb.2019.01.016DOI Listing
February 2019

ORP4L Extracts and Presents PIP from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells.

Cell Rep 2019 Feb;26(8):2166-2177.e9

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biology, Jinan University, Guangzhou 510632, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.01.082DOI Listing
February 2019

miR-107 inhibits CDK6 expression, differentiation, and lipid storage in human adipocytes.

Mol Cell Endocrinol 2019 01 24;479:110-116. Epub 2018 Sep 24.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland; Department of Anatomy, Faculty of Medicine, University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mce.2018.09.007DOI Listing
January 2019

Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.

Cell Calcium 2018 06 13;72:62-69. Epub 2018 Mar 13.

Åbo Akademi University, Tykistökatu 6A, 20520 Turku, Finland; Minerva Foundation Institute For Medical Research, Biomedicum Helsinki, 00290 Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceca.2018.03.001DOI Listing
June 2018

New medications targeting triglyceride-rich lipoproteins: Can inhibition of ANGPTL3 or apoC-III reduce the residual cardiovascular risk?

Atherosclerosis 2018 May 8;272:27-32. Epub 2018 Mar 8.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.019DOI Listing
May 2018

Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation.

FASEB J 2018 03 3;32(3):1281-1295. Epub 2018 Jan 3.

Minerva Foundation Institute for Medical Research, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201700604RDOI Listing
March 2018

MicroRNA-221-3p Regulates Angiopoietin-Like 8 (ANGPTL8) Expression in Adipocytes.

J Clin Endocrinol Metab 2017 11;102(11):4001-4012

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2017-00453DOI Listing
November 2017

Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition.

Chem Phys Lipids 2017 10 18;207(Pt B):246-252. Epub 2017 May 18.

Minerva Foundation Institute for Medical Research, Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2017.05.002DOI Listing
October 2017

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD.

J Hepatol 2017 07 22;67(1):128-136. Epub 2017 Feb 22.

Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2017.02.014DOI Listing
July 2017

Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Jul 18;1862(7):676-685. Epub 2017 Apr 18.

Department of Biosciences, University of Helsinki, FI-00014 Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2017.04.004DOI Listing
July 2017

Plant sterols, cholesterol precursors and oxysterols: Minute concentrations-Major physiological effects.

J Steroid Biochem Mol Biol 2017 05 28;169:4-9. Epub 2015 Dec 28.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland; Department of Anatomy, Faculty of Medicine, FI-00014 University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsbmb.2015.12.026DOI Listing
May 2017

Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307.

Antiviral Res 2017 04 11;140:37-44. Epub 2017 Jan 11.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.antiviral.2017.01.008DOI Listing
April 2017

Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans.

Thromb Haemost 2017 01 8;117(2):286-294. Epub 2016 Dec 8.

Susanna Lallukka, MD, Minerva Institute for Medical Research, Biomedicum Helsinki 2U, Room DP02b, Tukholmankatu 8, 00290 Helsinki, Finland, Tel.: +358 2941 25708, Fax: +358 9 471 71896, E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1160/TH16-09-0716DOI Listing
January 2017

ORP4L Facilitates Macrophage Survival via G-Protein-Coupled Signaling: ORP4L-/- Mice Display a Reduction of Atherosclerosis.

Circ Res 2016 Dec 11;119(12):1296-1312. Epub 2016 Oct 11.

From the Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou, China (W.Z., G.P., L.W., J.L., B.Z., X.C., H.M., C.L., D.Y.); Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland (S.L., V.M.O.); Division of Cardiac Surgery, the First Affiliated Hospital (J.O.) and Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China (M.X., J.X.); and U1011 Inserm, EGID, Université Lille, CHU Lille, Institut Pasteur de Lille, France (B.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.116.309603DOI Listing
December 2016

OSBP-Related Protein Family: Mediators of Lipid Transport and Signaling at Membrane Contact Sites.

Int Rev Cell Mol Biol 2016 18;321:299-340. Epub 2015 Nov 18.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.ircmb.2015.09.006DOI Listing
October 2016

ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival.

Nat Commun 2016 09 1;7:12702. Epub 2016 Sep 1.

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Department of Biotechnology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms12702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025801PMC
September 2016

A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity.

Atherosclerosis 2016 06 11;249:140-7. Epub 2016 Apr 11.

Department of Anatomy, Faculty of Medicine, University of Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.005DOI Listing
June 2016

MicroRNA-192* impairs adipocyte triglyceride storage.

Biochim Biophys Acta 2016 Apr 30;1861(4):342-51. Epub 2015 Dec 30.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland; Department of Anatomy, Faculty of Medicine, University of Helsinki, FI-00014 Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2015.12.019DOI Listing
April 2016

The Sec1/Munc18 Protein Groove Plays a Conserved Role in Interaction with Sec9p/SNAP-25.

Traffic 2016 Feb 21;17(2):131-53. Epub 2015 Dec 21.

Cell and Molecular Biology Program, Institute of Biotechnology, University of Helsinki, P.O. Box 56, FI-00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tra.12349DOI Listing
February 2016

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease.

Physiol Rep 2016 Jan;4(1)

Minerva Foundation Institute for Medical Research, Helsinki, Finland Institute of Biomedicine, Anatomy, University of Helsinki, Helsinki, Finland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14814/phy2.12661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760405PMC
January 2016

OSBP-Related Protein Family in Lipid Transport Over Membrane Contact Sites.

Authors:
Vesa M Olkkonen

Lipid Insights 2015 12;8(Suppl 1):1-9. Epub 2015 Nov 12.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland. ; Department of Anatomy, Faculty of Medicine, University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://www.la-press.com/redirect_file.php?fileId=6949&filena
Web Search
http://www.la-press.com/osbp-related-protein-family-in-lipid
Publisher Site
http://dx.doi.org/10.4137/LPI.S31726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685180PMC
December 2015

Bimolecular fluorescence complementation (BiFC) technique in yeast Saccharomyces cerevisiae and mammalian cells.

Methods Mol Biol 2015 ;1270:277-88

Research Program in Cell and Molecular Biology, Institute of Biotechnology, University of Helsinki, 00014, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-2309-0_20DOI Listing
November 2015

Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin.

J Clin Endocrinol Metab 2015 Oct 23;100(10):E1299-307. Epub 2015 Jul 23.

Minerva Foundation Institute for Medical Research (P.A.N.H., J.S., S.S., R.M., J.P., V.M.O., H.J.-J.), FI-00290 Helsinki, Finland; Public Health Genomics Unit (J.S., J.M., C.E., M.J.), National Institute for Health and Welfare, Helsinki, FI-00290 Helsinki, Finland; Department of Medicine (S.S.), FI-00014 University of Helsinki, Helsinki, Finland; Department of Internal Medicine (F.Q.), University of Texas Southwestern Medical Center, Dallas, Texas 75390; Haartman Institute (A.P., O.R.), FI-00014 University of Helsinki, FI-00029 Helsinki, Finland; Department of Surgery (M.L.), Helsinki University Central Hospital, University of Helsinki, FI-00029 Helsinki, Finland; Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research (C.M.S.), University of Toledo College of Medicine, Toledo, Ohio 43614; Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine (P.F.-P., M.W.), University of Ulm, D-89075 Ulm Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2015-1254DOI Listing
October 2015

Sterol liganding of OSBP-related proteins (ORPs) regulates the subcellular distribution of ORP-VAPA complexes and their impacts on organelle structure.

Steroids 2015 Jul 11;99(Pt B):248-58. Epub 2015 Feb 11.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.steroids.2015.01.027DOI Listing
July 2015

Ligand-dependent localization and function of ORP-VAP complexes at membrane contact sites.

Cell Mol Life Sci 2015 May 25;72(10):1967-87. Epub 2014 Nov 25.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, 00290, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-014-1786-xDOI Listing
May 2015

OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.

Exp Cell Res 2015 Feb 29;331(2):278-91. Epub 2014 Oct 29.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland; Institute of Biomedicine/Anatomy, FI-00014 University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2014.10.019DOI Listing
February 2015

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.

Cell Rep 2015 Feb 29;10(4):600-15. Epub 2015 Jan 29.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584CL Utrecht, the Netherlands; Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, 6525GA Nijmegen, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.12.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383725PMC
February 2015

Impact of non-alcoholic fatty liver disease on liver volume in humans.

Hepatol Res 2015 Jan 18;45(2):210-9. Epub 2014 Jul 18.

Minerva Foundation Institute for Medical Research, Helsinki, Finland; Department of Endocrinology, Zhongshan Hospital, Fudan University, Shanghai, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hepr.12338DOI Listing
January 2015

Extendable blocking probe in reverse transcription for analysis of RNA variants with superior selectivity.

Nucleic Acids Res 2015 Jan 5;43(1):e4. Epub 2014 Nov 5.

Minerva Foundation Institute for Medical Research, Helsinki, 00290, Finland Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, FI-00014, Finland Department of Women's and Children's Health, Karolinska Institutet, Stockholm, SE-17176, Sweden

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku1048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288146PMC
January 2015

A vertebrate model for the study of lipid binding/transfer protein function: conservation of OSBP-related proteins between zebrafish and human.

Biochem Biophys Res Commun 2014 Apr 8;446(3):675-80. Epub 2013 Dec 8.

Minerva Foundation Institute for Medical Research, Helsinki, Finland; Institute of Biomedicine, Anatomy, University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0006291X130205
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2013.12.002DOI Listing
April 2014

Cholesterol precursors: more than mere markers of biosynthesis.

Curr Opin Lipidol 2014 Apr;25(2):133-9

aSchool of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, New South Wales, Australia bInstitute of Biomedicine, Anatomy, University of Helsinki cMinerva Foundation Institute for Medical Research, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOL.0000000000000038DOI Listing
April 2014

OSBP-related protein 8 (ORP8) interacts with Homo sapiens sperm associated antigen 5 (SPAG5) and mediates oxysterol interference of HepG2 cell cycle.

Exp Cell Res 2014 Apr 11;322(2):227-35. Epub 2014 Jan 11.

Department of Biotechnology, Jinan University, Guangzhou 510632, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2014.01.002DOI Listing
April 2014

PNPLA3 mediates hepatocyte triacylglycerol remodeling.

J Lipid Res 2014 Apr 7;55(4):739-46. Epub 2014 Feb 7.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://www.jlr.org/content/55/4/739.full.pdf
Web Search
http://www.jlr.org/cgi/doi/10.1194/jlr.M046607
Publisher Site
http://dx.doi.org/10.1194/jlr.M046607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966707PMC
April 2014

ABC-cassette transporter 1 (ABCA1) expression in epithelial cells in Chlamydia pneumoniae infection.

Microb Pathog 2013 Aug-Sep;61-62:57-61. Epub 2013 May 21.

Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micpath.2013.05.006DOI Listing
February 2014

Egg consumption and risk of bladder cancer: a meta-analysis.

Nutr Cancer 2013 ;65(4):538-46

Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2013.770041DOI Listing
December 2013

OSBP-related proteins: liganding by glycerophospholipids opens new insight into their function.

Authors:
Vesa M Olkkonen

Molecules 2013 Nov 5;18(11):13666-79. Epub 2013 Nov 5.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, Helsinki FI-00290, Finland.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1420-3049/18/11/13666
Publisher Site
http://dx.doi.org/10.3390/molecules181113666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270239PMC
November 2013

Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism.

Prog Lipid Res 2013 Oct 2;52(4):529-38. Epub 2013 Jul 2.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, FI-00290 Helsinki, Finland; Institute of Biomedicine, Anatomy, Biomedicum 1, Haartmaninkatu 8, FI-00014 University of Helsinki, Finland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.plipres.2013.06.004DOI Listing
October 2013

The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models.

Cardiovasc Res 2013 Sep 10;99(4):716-23. Epub 2013 Jun 10.

Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://cardiovascres.oxfordjournals.org/content/cardiovascre
Web Search
http://cardiovascres.oxfordjournals.org/cgi/doi/10.1093/cvr/
Publisher Site
http://dx.doi.org/10.1093/cvr/cvt148DOI Listing
September 2013

Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism.

Biochem Pharmacol 2013 Jul 18;86(1):89-95. Epub 2013 Feb 18.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2013.02.016DOI Listing
July 2013

Association between baseline lipoprotein (a) levels and restenosis after coronary stenting: meta-analysis of 9 cohort studies.

Atherosclerosis 2013 Apr 21;227(2):360-6. Epub 2013 Jan 21.

First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2013.01.014DOI Listing
April 2013

Modification of the lipidome in RAW264.7 macrophage subjected to stable silencing of oxysterol-binding proteins.

Biochimie 2013 Mar 16;95(3):538-47. Epub 2012 May 16.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2012.05.004DOI Listing
March 2013

ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.

Biochim Biophys Acta 2012 Dec 11;1821(12):1472-84. Epub 2012 Aug 11.

Institute of Biomedicine, Anatomy, PO Box 63, FI-00014 University of Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2012.08.004DOI Listing
December 2012

Identification of urinary Gc-globulin as a novel biomarker for bladder cancer by two-dimensional fluorescent differential gel electrophoresis (2D-DIGE).

J Proteomics 2012 Dec 9;77:225-36. Epub 2012 Sep 9.

Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jprot.2012.09.002DOI Listing
December 2012

Macrophage oxysterols and their binding proteins: roles in atherosclerosis.

Authors:
Vesa M Olkkonen

Curr Opin Lipidol 2012 Oct;23(5):462-70

Minerva Foundation Institute for Medical Research bInstitute of Biomedicine, Anatomy, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/MOL.0b013e328356dba0DOI Listing
October 2012

Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity.

Exp Cell Res 2012 Sep 5;318(15):1933-45. Epub 2012 Jun 5.

Minerva Foundation Institute for Medical Research, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2012.05.026DOI Listing
September 2012

Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.

Cell Mol Life Sci 2012 Jun 20;69(12):2075-89. Epub 2012 Jan 20.

National Institute for Health and Welfare and FIMM, Institute for Molecular Medicine Finland, Biomedicum Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-011-0913-1DOI Listing
June 2012

PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis.

Am J Physiol Endocrinol Metab 2012 May 14;302(9):E1063-9. Epub 2012 Feb 14.

Minerva Foundation Institute for Medical Research, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://www.physiology.org/doi/10.1152/ajpendo.00125.2011
Publisher Site
http://dx.doi.org/10.1152/ajpendo.00125.2011DOI Listing
May 2012

Oxysterols and their cellular effectors.

Biomolecules 2012 Feb 15;2(1):76-103. Epub 2012 Feb 15.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Tukholmankatu 8, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biom2010076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030866PMC
February 2012

OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability.

Exp Cell Res 2011 Oct 6;317(16):2353-63. Epub 2011 Jun 6.

Department of Biotechnology, Jinan University, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2011.05.028DOI Listing
October 2011

Cytoplasmic oxysterol-binding proteins: sterol sensors or transporters?

Chem Phys Lipids 2011 Sep 17;164(6):443-50. Epub 2011 Mar 17.

Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2011.03.002DOI Listing
September 2011

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.

Nat Cell Biol 2011 Apr 27;13(4):434-46. Epub 2011 Mar 27.

Department of Mouse Genetics and Metabolism, Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, University Hospital Cologne, Max Planck Institute for Neurological Research, Zülpicher Strasse 47, D-50674 Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2211DOI Listing
April 2011

Sterol binding by OSBP-related protein 1L regulates late endosome motility and function.

Cell Mol Life Sci 2011 Feb 6;68(3):537-51. Epub 2010 Aug 6.

Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Tukholmankatu 8, 00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-010-0470-zDOI Listing
February 2011

OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface.

Exp Cell Res 2010 Nov 16;316(19):3304-16. Epub 2010 Jun 16.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, and National Institute for Health and Welfare/Public Health Genomics Unit, Biomedicum 1, FI-00290, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2010.06.008DOI Listing
November 2010

OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.

J Lipid Res 2009 Jul 17;50(7):1305-15. Epub 2009 Feb 17.

National Institute for Health and Welfare, University of Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M800661-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694330PMC
July 2009

Cab45b, a Munc18b-interacting partner, regulates exocytosis in pancreatic beta-cells.

J Biol Chem 2009 Jul 1;284(31):20840-7. Epub 2009 Jun 1.

Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.017467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742849PMC
July 2009

Regulation of exocytotic protein expression and Ca2+-dependent peptide secretion in astrocytes.

J Neurochem 2009 Jul 15;110(1):143-56. Epub 2009 May 15.

Department of Cell Biology, University of Barcelona, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1471-4159.2009.06116.xDOI Listing
July 2009

Interactions of oxysterols with membranes and proteins.

Mol Aspects Med 2009 Jun 25;30(3):123-33. Epub 2009 Feb 25.

National Public Health Institute and FIMM, Institute for Molecular Medicine Finland, Biomedicum, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S009829970900005
Publisher Site
http://dx.doi.org/10.1016/j.mam.2009.02.004DOI Listing
June 2009

Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages.

Arterioscler Thromb Vasc Biol 2009 Jun 19;29(6):883-8. Epub 2009 Mar 19.

Institute of Biomedicine/Anatomy, Haartmaninkatu 8, 00014 University of Helsinki, Finland.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/ATVBAHA.108.179481
Publisher Site
http://dx.doi.org/10.1161/ATVBAHA.108.179481DOI Listing
June 2009

Characteristics of oxysterol binding proteins.

Int Rev Cytol 2008 ;265:253-85

Department of Molecular Medicine, National Public Health Institute, Biomedicum, FI-00290 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0074-7696(07)65007-4DOI Listing
April 2008

The R-Ras interaction partner ORP3 regulates cell adhesion.

J Cell Sci 2008 Mar 12;121(Pt 5):695-705. Epub 2008 Feb 12.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, FI-00251 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://jcs.biologists.org/cgi/doi/10.1242/jcs.016964
Publisher Site
http://dx.doi.org/10.1242/jcs.016964DOI Listing
March 2008

OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages.

J Biol Chem 2008 Jan 8;283(1):332-40. Epub 2007 Nov 8.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, FI-00251 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M705313200DOI Listing
January 2008

Cholesterol efflux from macrophage foam cells is enhanced by active phospholipid transfer protein through generation of two types of acceptor particles.

Biochemistry 2007 Oct 27;46(42):11979-86. Epub 2007 Sep 27.

National Public Health Institute, Department of Molecular Medicine, Biomedicum, P.O. Box 104, FI-00251 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi700833hDOI Listing
October 2007

Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice.

Arterioscler Thromb Vasc Biol 2007 Jul 3;27(7):1618-24. Epub 2007 May 3.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, P.O. Box 104, FI-00251 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.107.144121DOI Listing
July 2007

Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis.

Arterioscler Thromb Vasc Biol 2007 May 15;27(5):1108-14. Epub 2007 Feb 15.

Department of Molecular Medicine, National Public Health Institute, Biomedicum, P.O.Box 104, FI-00251 Helsinki, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.106.138545DOI Listing
May 2007