Veronique Witko-Sarsat

Veronique Witko-Sarsat

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Veronique Witko-Sarsat

Veronique Witko-Sarsat

Publications by authors named "Veronique Witko-Sarsat"

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Comment on: Subclassifying ANCA-associated vasculitis: a unifying view of disease spectrum.

Rheumatology (Oxford) 2020 Mar 12. Epub 2020 Mar 12.

Department of Internal Medicine, Université Paris-Descartes, Paris, France.

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http://dx.doi.org/10.1093/rheumatology/keaa068DOI Listing
March 2020

Inflammasome activation: Neutrophils go their own way.

J Leukoc Biol 2019 03 5;105(3):433-436. Epub 2019 Feb 5.

Cochin Institute, INSERM U1016, CNRS UMR 8104, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1002/JLB.3CE1118-433RDOI Listing
March 2019

Regulation of macrophage activation by proteins expressed on apoptotic neutrophils: Subversion towards autoimmunity by proteinase 3.

Eur J Clin Invest 2018 Nov;48 Suppl 2:e12990

Department of Biology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel.

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http://dx.doi.org/10.1111/eci.12990DOI Listing
November 2018

From Starfish Oocytes to Inflammation: The Unforeseeable Destiny of Roscovitine in Cystic Fibrosis.

J Innate Immun 2016 26;8(4):327-9. Epub 2016 Apr 26.

INSERM U1016, Institut Cochin, and CNRS-UMR 8104, Université Paris Descartes, Sorbonne Paris Cité, and Center of Excellence, Labex Inflamex, Paris, France.

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http://dx.doi.org/10.1159/000445967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738786PMC
May 2018

Granulomatosis with polyangiitis (Wegener granulomatosis): A proteinase-3 driven disease?

Joint Bone Spine 2018 03 8;85(2):185-189. Epub 2017 May 8.

Inserm U1016, Laboratoire d'excellence INFLAMEX, Institut Cochin, Université Paris Descartes, CNRS-UMR 8104, Université Sorbonne Paris Cité, 75014 Paris, France.

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http://dx.doi.org/10.1016/j.jbspin.2017.05.004DOI Listing
March 2018

Harnessing Neutrophil Survival Mechanisms during Chronic Infection by : Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis.

Front Cell Infect Microbiol 2017 30;7:243. Epub 2017 Jun 30.

Institut National de la Santé et de la Recherche Médicale, U1016, Institut CochinParis, France.

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http://dx.doi.org/10.3389/fcimb.2017.00243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492487PMC
March 2018

Proteinase 3: the odd one out that became an autoantigen.

J Leukoc Biol 2017 09 25;102(3):689-698. Epub 2017 May 25.

Institut National de la Santé et de la Recherche Médicale, U1016, Institut Cochin, Paris, France;

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http://dx.doi.org/10.1189/jlb.3MR0217-069RDOI Listing
September 2017

Molecular analysis of vascular smooth muscle cells from patients with giant cell arteritis: Targeting endothelin-1 receptor to control proliferation.

Autoimmun Rev 2017 Apr 14;16(4):398-406. Epub 2017 Feb 14.

Institut Cochin, INSERM U1016, CNRS UMR 8104, LabEx INFLAMEX, Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Pôle de Médecine Interne, Centre de Référence pour les vascularites nécrosantes et la sclérodermie systémique, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.02.006DOI Listing
April 2017

Proliferating cell nuclear antigen in neutrophil fate.

Immunol Rev 2016 09;273(1):344-56

INSERM U1016, Paris, France.

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http://dx.doi.org/10.1111/imr.12449DOI Listing
September 2016

Anoxia and glucose supplementation preserve neutrophil viability and function.

Blood 2016 08 8;128(7):993-1002. Epub 2016 Jul 8.

Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur, Paris, France, INSERM Unité 786, Paris, France; Laboratoire de Thérapie Cellulaire, Gustave Roussy Cancer Campus, Villejuif, France.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2015-11
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http://dx.doi.org/10.1182/blood-2015-11-680918DOI Listing
August 2016

Proteinase 3 Is a Phosphatidylserine-binding Protein That Affects the Production and Function of Microvesicles.

J Biol Chem 2016 May 9;291(20):10476-89. Epub 2016 Mar 9.

From the INSERM, U1016, Institut Cochin, 75014 Paris, France, CNRS-UMR8104, 75014 Paris, France, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France, Center of Excellence, Labex Inflamex, 75013 Paris, France,

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http://dx.doi.org/10.1074/jbc.M115.698639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865899PMC
May 2016

[Proteinase 3: a new danger signal and a double agent in vasculitis].

Med Sci (Paris) 2016 May 25;32(5):450-2. Epub 2016 May 25.

Inserm UMR1098, EFS BFC, université Bourgogne Franche-Comté, LabEx LipSTIC, Besançon, France.

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http://dx.doi.org/10.1051/medsci/20163205008DOI Listing
May 2016

Human neutrophils in auto-immunity.

Semin Immunol 2016 04 29;28(2):159-73. Epub 2016 Mar 29.

INSERM, U1016, Institut Cochin, Paris, France; CNRS UMR 8104, 75014 Paris, France; Université Paris-Descartes, 75014, France; Center of Excellence, LABEX Inflamex, 75014, France. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2016.03.004DOI Listing
April 2016

Dividing the Janus vasculitis? Pathophysiology of eosinophilic granulomatosis with polyangitis.

Autoimmun Rev 2016 Feb 23;15(2):139-45. Epub 2015 Oct 23.

INSERM, U1016, Institut Cochin, Paris, France; CNRS, UMR8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Université Paris Descartes, Faculté de Médecine, Pôle de Médecine Interne, Centre de référence pour les vascularites nécrosantes et la sclérodermie systémique, hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2015.10.006DOI Listing
February 2016

Promoting apoptosis of neutrophils and phagocytosis by macrophages: novel strategies in the resolution of inflammation.

Swiss Med Wkly 2015 21;145:w14056. Epub 2015 Feb 21.

INSERM U1016, Cochin Institute Paris, France; Paris Descartes University, Paris, France; CNRS-UMR 8104, Paris, France; Centre of Excellence, LABEX Inflamex, University Paris Diderot, France.

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http://dx.doi.org/10.4414/smw.2015.14056DOI Listing
September 2015

Autophagy and innate immunity.

J Innate Immun 2013 15;5(5):425-6. Epub 2013 Jun 15.

INSERM U1016, Cochin Institute, CNRS UMR8104, Université Paris Descartes, Université Paris Diderot, Sorbonne Paris Cité et Laboratoire d'Excellence INFLAMEX, Paris, France.

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http://dx.doi.org/10.1159/000353153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741537PMC
November 2013

Characterization of cytosolic proliferating cell nuclear antigen (PCNA) in neutrophils: antiapoptotic role of the monomer.

J Leukoc Biol 2013 Oct 3;94(4):723-31. Epub 2013 Jul 3.

1.Cochin Institute, 27 bis rue du Faubourg Saint Jacques, 75014 Paris, France.

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http://dx.doi.org/10.1189/jlb.1212637DOI Listing
October 2013

L34. Neutrophils in ANCA-associated vasculitis: still under investigation.

Presse Med 2013 Apr 6;42(4 Pt 2):595-7. Epub 2013 Mar 6.

Inserm U1016, institut Cochin, université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2013.01.034DOI Listing
April 2013

Targeting cytosolic proliferating cell nuclear antigen in neutrophil-dominated inflammation.

Front Immunol 2012 9;3:311. Epub 2012 Oct 9.

Department of Immunology and Hematology, INSERM U1016, Cochin Institute Paris France ; Paris Descartes University Paris, France ; CNRS-UMR 8104 Paris, France.

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http://dx.doi.org/10.3389/fimmu.2012.00311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501000PMC
November 2012

[Pathophysiology of ANCA-associated vasculitides].

Presse Med 2012 Oct 23;41(10):996-1003. Epub 2012 Aug 23.

Institut Cochin, Inserm U 1016, Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2012.07.007DOI Listing
October 2012

Regulating neutrophil apoptosis: new players enter the game.

Trends Immunol 2011 Mar 12;32(3):117-24. Epub 2011 Feb 12.

Institut National de la Santé et de la Recherche Médicale Unité 1016, 75014 Paris, France.

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http://dx.doi.org/10.1016/j.it.2011.01.001DOI Listing
March 2011

Apoptosis, cell death and inflammation.

J Innate Immun 2010 16;2(3):201-3. Epub 2010 Mar 16.

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http://dx.doi.org/10.1159/000296505DOI Listing
September 2010

Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.

FEBS J 2010 May;277(10):2238-54

Dipartimento di Fisica, University of Cagliari (CA), Italy.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07659.xDOI Listing
May 2010

Interaction of proteinase 3 with its associated partners: implications in the pathogenesis of Wegener's granulomatosis.

Curr Opin Rheumatol 2010 Jan;22(1):1-7

Inserm U567 and Université Paris Descartes, Cochin Hospital, Paris, France.

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http://dx.doi.org/10.1097/BOR.0b013e3283331594DOI Listing
January 2010

Neutrophils and B lymphocytes in ANCA-associated vasculitis.

APMIS Suppl 2009 Jun(127):27-31

Inserm U845, Necker Hospital and Université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1111/j.1600-0463.2009.02473.xDOI Listing
June 2009

The role of neutrophils and monocytes in innate immunity.

Contrib Microbiol 2008 ;15:118-146

INSERM U845, Necker Hospital, Paris, France.

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https://www.karger.com/Article/FullText/136335
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http://dx.doi.org/10.1159/000136335DOI Listing
September 2008

Computational prediction of the binding site of proteinase 3 to the plasma membrane.

Proteins 2008 Jun;71(4):1655-69

Computational Biology Unit, BCCS, University of Bergen, N-5008 Bergen, Norway.

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http://dx.doi.org/10.1002/prot.21853DOI Listing
June 2008

Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3.

J Biol Chem 2007 Oct 6;282(41):29998-30004. Epub 2007 Aug 6.

William Harvey Research Institute, Barts and The London, Charterhouse Square, London EC1M 6BQ, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M702876200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772024PMC
October 2007

Changes in glycation and oxidation markers in patients starting peritoneal dialysis: a pilot study.

Perit Dial Int 2006 Mar-Apr;26(2):207-12

Laboratory of Vascular and Cellular Biology, National Institute of Blood Transfusion, France.

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August 2006

Respective role of uraemic toxins and myeloperoxidase in the uraemic state.

Nephrol Dial Transplant 2006 Jun 13;21(6):1555-63. Epub 2006 Feb 13.

Université Paris 5, CNRS UMR 8601, 45 rue des Saints Pères, 75270 Paris Cedex 06, France.

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http://dx.doi.org/10.1093/ndt/gfl007DOI Listing
June 2006

Inspection of the binding sites of proteinase3 for the design of a highly specific substrate.

J Med Chem 2006 Feb;49(4):1248-60

Computational Biology Unit, BCCS, University of Bergen, N-5008 Bergen, Norway.

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http://dx.doi.org/10.1021/jm051018tDOI Listing
February 2006

Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.

J Biol Chem 2005 Aug 23;280(34):30242-53. Epub 2005 Jun 23.

Laboratoire de Spectrométrie de Masse des Protéines, Institut de Biologie Structurale Jean-Pierre Ebel, Commissariat à l'Energie Atomique-CNRS-Université Joseph Fourier, Grenoble 38000, France.

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http://dx.doi.org/10.1074/jbc.M414609200DOI Listing
August 2005

Proteinase-3 induces procaspase-3 activation in the absence of apoptosis: potential role of this compartmentalized activation of membrane-associated procaspase-3 in neutrophils.

J Immunol 2005 May;174(10):6381-90

Institut National de la Santé et de la Recherche Médicale Unité 507, Université René Descartes, Paris 5, Hôpital Necker, Paris, France.

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http://dx.doi.org/10.4049/jimmunol.174.10.6381DOI Listing
May 2005

Biochemical and spectrophotometric significance of advanced oxidized protein products.

Biochim Biophys Acta 2004 Jun;1689(2):91-102

Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (CNRS UMR 8601) Université Paris 5, Faculty of Medicine, 45 rue des Saints Pères, 75270 Paris Cedex 06, France.

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http://dx.doi.org/10.1016/j.bbadis.2004.02.008DOI Listing
June 2004

Apoptosis-induced proteinase 3 membrane expression is independent from degranulation.

J Leukoc Biol 2004 Jan 2;75(1):87-98. Epub 2003 Oct 2.

Inserm U507, Hôpital Necker, 161, rue de Sèvres, 75015 Paris, France.

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http://dx.doi.org/10.1189/jlb.0203079DOI Listing
January 2004

Immune system dysregulation in uremia: role of oxidative stress.

Blood Purif 2002 ;20(5):481-4

INSERM U507 and Department of Nephrology, Necker Hospital, Paris, France.

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http://dx.doi.org/10.1159/000063558DOI Listing
July 2003

Are advanced oxidation protein products potential uremic toxins?

Kidney Int Suppl 2003 May(84):S11-4

INSERM U507, Necker Hospital, Paris, France.

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http://dx.doi.org/10.1046/j.1523-1755.63.s84.47.xDOI Listing
May 2003

Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation.

J Biol Chem 2002 Dec 26;277(49):47338-47. Epub 2002 Sep 26.

INSERM U507, Hôpital Necker, 161, rue de Sèvres, and INSERM U370, Faculté de Médecine Necker, 156 rue de Vaugirard, 75015 Paris, France and INSERM U533, Faculté de Médecine, 1 rue Gaston Veil, 44000 Nantes, France.

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http://dx.doi.org/10.1074/jbc.M202789200DOI Listing
December 2002