Publications by authors named "Veronika Vymetalkova"

49Publications

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.

Authors:
Minta Thomas Lori C Sakoda Michael Hoffmeister Elisabeth A Rosenthal Jeffrey K Lee Franzel J B van Duijnhoven Elizabeth A Platz Anna H Wu Christopher H Dampier Albert de la Chapelle Alicja Wolk Amit D Joshi Andrea Burnett-Hartman Andrea Gsur Annika Lindblom Antoni Castells Aung Ko Win Bahram Namjou Bethany Van Guelpen Catherine M Tangen Qianchuan He Christopher I Li Clemens Schafmayer Corinne E Joshu Cornelia M Ulrich D Timothy Bishop Daniel D Buchanan Daniel Schaid David A Drew David C Muller David Duggan David R Crosslin Demetrius Albanes Edward L Giovannucci Eric Larson Flora Qu Frank Mentch Graham G Giles Hakon Hakonarson Heather Hampel Ian B Stanaway Jane C Figueiredo Jeroen R Huyghe Jessica Minnier Jenny Chang-Claude Jochen Hampe John B Harley Kala Visvanathan Keith R Curtis Kenneth Offit Li Li Loic Le Marchand Ludmila Vodickova Marc J Gunter Mark A Jenkins Martha L Slattery Mathieu Lemire Michael O Woods Mingyang Song Neil Murphy Noralane M Lindor Ozan Dikilitas Paul D P Pharoah Peter T Campbell Polly A Newcomb Roger L Milne Robert J MacInnis Sergi Castellví-Bel Shuji Ogino Sonja I Berndt Stéphane Bézieau Stephen N Thibodeau Steven J Gallinger Syed H Zaidi Tabitha A Harrison Temitope O Keku Thomas J Hudson Veronika Vymetalkova Victor Moreno Vicente Martín Volker Arndt Wei-Qi Wei Wendy Chung Yu-Ru Su Richard B Hayes Emily White Pavel Vodicka Graham Casey Stephen B Gruber Robert E Schoen Andrew T Chan John D Potter Hermann Brenner Gail P Jarvik Douglas A Corley Ulrike Peters Li Hsu

Am J Hum Genet 2020 Jul 29. Epub 2020 Jul 29.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2020.07.006DOI Listing
July 2020

DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers.

Int J Mol Sci 2020 Aug 3;21(15). Epub 2020 Aug 3.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21155561DOI Listing
August 2020

Distant Metastasis in Colorectal Cancer Patients-Do We Have New Predicting Clinicopathological and Molecular Biomarkers? A Comprehensive Review.

Int J Mol Sci 2020 Jul 24;21(15). Epub 2020 Jul 24.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21155255DOI Listing
July 2020

Methylation-Based Therapies for Colorectal Cancer.

Cells 2020 Jun 24;9(6). Epub 2020 Jun 24.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14 200 Prague, Czech Republic.

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http://dx.doi.org/10.3390/cells9061540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349319PMC
June 2020

Colorectal Adenomas-Genetics and Searching for New Molecular Screening Biomarkers.

Int J Mol Sci 2020 May 5;21(9). Epub 2020 May 5.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21093260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247353PMC
May 2020

Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients.

Int J Mol Sci 2020 Apr 2;21(7). Epub 2020 Apr 2.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.

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http://dx.doi.org/10.3390/ijms21072473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177219PMC
April 2020

Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.

Gastroenterology 2020 04 27;158(5):1300-1312.e20. Epub 2019 Dec 27.

Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1053/j.gastro.2019.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152801PMC
April 2020

5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future.

Pharmacol Ther 2020 02 19;206:107447. Epub 2019 Nov 19.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00 Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2019.107447DOI Listing
February 2020

Diagnostic and prognostic impact of cell-free DNA in human cancers: Systematic review.

Mutat Res 2019 Jul - Sep;781:100-129. Epub 2019 May 11.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Albertov 4, Charles University, 12800 Prague, Czech Republic; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 32300 Pilsen, Czech Republic.

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http://dx.doi.org/10.1016/j.mrrev.2019.05.002DOI Listing
March 2020

Fusobacterium nucleatum tumor DNA levels are associated with survival in colorectal cancer patients.

Eur J Clin Microbiol Infect Dis 2019 Oct 31;38(10):1891-1899. Epub 2019 Jul 31.

Cancer Biology and Therapeutics Group, School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Dublin, D04 V1W8, Ireland.

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http://dx.doi.org/10.1007/s10096-019-03649-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778531PMC
October 2019

Circulating biomarkers for early detection and clinical management of colorectal cancer.

Mol Aspects Med 2019 10 14;69:107-122. Epub 2019 Jun 14.

Gastrointestinal & Pancreatic Oncology Group, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD) / Hospital Clínic of Barcelona/ Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.06.002DOI Listing
October 2019

DNA methylation and chromatin modifiers in colorectal cancer.

Mol Aspects Med 2019 10 30;69:73-92. Epub 2019 Apr 30.

Experimental Tumorpathology, Institute of Pathology, University Hospital of Friedrich-Alexander-University Erlangen-Nürnberg, Universitätsstrasse 22, 91054, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.04.002DOI Listing
October 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Genetic variation of acquired structural chromosomal aberrations.

Mutat Res Genet Toxicol Environ Mutagen 2018 Dec 19;836(Pt A):13-21. Epub 2018 May 19.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, D69120, Germany; Center for Primary Health Care Research, Lund University, Malmö, 214 28, Sweden.

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https://www.researchgate.net/publication/236938844_From_DNA_
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https://linkinghub.elsevier.com/retrieve/pii/S13835718183002
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http://dx.doi.org/10.1016/j.mrgentox.2018.05.014DOI Listing
December 2018

Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review.

Int J Mol Sci 2018 Oct 26;19(11). Epub 2018 Oct 26.

Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 00 Prague, Czech Republic.

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http://www.mdpi.com/1422-0067/19/11/3356
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http://dx.doi.org/10.3390/ijms19113356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274807PMC
October 2018

Base excision repair capacity as a determinant of prognosis and therapy response in colon cancer patients.

DNA Repair (Amst) 2018 12 1;72:77-85. Epub 2018 Oct 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00, Prague, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00, Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2018.09.006DOI Listing
December 2018

DNA and chromosomal damage in medical workers exposed to anaesthetic gases assessed by the lymphocyte cytokinesis-block micronucleus (CBMN) assay. A critical review.

Mutat Res 2016 Oct - Dec;770(Pt A):26-34. Epub 2016 Apr 8.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00 Prague, Czech Republic; Human Genetics Foundation (HuGeF) Turin, via Nizza 52, 10126 Turin, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S13835742163002
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http://dx.doi.org/10.1016/j.mrrev.2016.04.003DOI Listing
May 2017

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.

Carcinogenesis 2017 01 1;38(1):28-39. Epub 2016 Nov 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgw114DOI Listing
January 2017

Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.

Adv Exp Med Biol 2016 ;937:123-49

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00, Prague, Czech Republic.

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http://dx.doi.org/10.1007/978-3-319-42059-2_7DOI Listing
July 2017

Epigenome-wide analysis of DNA methylation reveals a rectal cancer-specific epigenomic signature.

Epigenomics 2016 09 16;8(9):1193-207. Epub 2016 Aug 16.

Department of Laboratory Medicine, Örebro University; Örebro, Sweden.

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http://dx.doi.org/10.2217/epi-2016-0044DOI Listing
September 2016

Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans.

Cancer Lett 2016 10 15;380(2):442-6. Epub 2016 Jul 15.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835163040
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http://dx.doi.org/10.1016/j.canlet.2016.07.011DOI Listing
October 2016

Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects.

Carcinogenesis 2015 Nov 8;36(11):1299-306. Epub 2015 Sep 8.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany, Center for Primary Health Care Research, Lund University, 20506 Malmö, Sweden and.

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http://dx.doi.org/10.1093/carcin/bgv127DOI Listing
November 2015

Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes.

PLoS One 2015 30;10(7):e0134463. Epub 2015 Jul 30.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine Charles University, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134463PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520609PMC
May 2016

Metabolic gene variants associated with chromosomal aberrations in healthy humans.

Genes Chromosomes Cancer 2015 Apr 27;54(4):260-6. Epub 2015 Jan 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22239DOI Listing
April 2015

Telomere length in circulating lymphocytes: Association with chromosomal aberrations.

Genes Chromosomes Cancer 2015 Mar 27;54(3):194-6. Epub 2014 Nov 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center Heidelberg, (DKFZ), Im Neuenheimer Feld 580, 69121, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22225DOI Listing
March 2015

Polymorphisms in microRNA genes as predictors of clinical outcomes in colorectal cancer patients.

Carcinogenesis 2015 Jan 3;36(1):82-6. Epub 2014 Nov 3.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, 14200 Prague, Czech Republic, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, 12108 Prague, Czech Republic.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgu224DOI Listing
January 2015

Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

PLoS One 2014 28;9(10):e111061. Epub 2014 Oct 28.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Center of Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211713PMC
January 2016

Variations in mismatch repair genes and colorectal cancer risk and clinical outcome.

Mutagenesis 2014 Jul 22;29(4):259-65. Epub 2014 Apr 22.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14200 Prague, Czech Republic, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Katerinska 32, 12800 Prague, Czech Republic.

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http://dx.doi.org/10.1093/mutage/geu014DOI Listing
July 2014