Publications by authors named "Verena I Gaidzik"

39Publications

Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'.

Eur J Cancer 2020 Aug 7;135:1-7. Epub 2020 Jun 7.

University Comprehensive Cancer Center Hamburg, Department of Oncology, Hematology with Section Bone Marrow Transplantation and Pneumology, University Medical Center Hamburg-Eppendorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.04.019DOI Listing
August 2020

The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.

Exp Hematol 2017 11 28;55:76-85.e3. Epub 2017 Jul 28.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; Department of Hematology/Oncology, Medical Center Augsburg, Augsburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X173070
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http://dx.doi.org/10.1016/j.exphem.2017.07.009DOI Listing
November 2017

Evaluating the impact of genetic and epigenetic aberrations on survival and response in acute myeloid leukemia patients receiving epigenetic therapy.

Ann Hematol 2017 Apr 5;96(4):559-565. Epub 2017 Jan 5.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Hugstetterstr. 55, 79106, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00277-016-2912-7DOI Listing
April 2017

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia.

Blood 2017 02 21;129(7):e13-e25. Epub 2016 Dec 21.

Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1182/blood-2016-07-726877DOI Listing
February 2017

Genomic Classification and Prognosis in Acute Myeloid Leukemia.

N Engl J Med 2016 Jun;374(23):2209-2221

Cancer Genome Project, Wellcome Trust Sanger Institute (E.P., M.G., N.D.R., N.B., G.G., P.V.L., I.M., L.M., S.M., S.O., K.R., D.R.J., J.W.T., A.P.B., P.J.C.), and the European Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI) (M.G.), Hinxton, the Centre for Evolution and Cancer, Institute of Cancer Research, London (N.E.P., M.F.G.), and the Department of Haematology, University of Cambridge, Cambridge (N.B.) - all in the United Kingdom; the Departments of Epidemiology and Biostatistics and Cancer Biology, the Center for Molecular Oncology and the Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York (E.P.); the Department of Internal Medicine III, Ulm University, Ulm (L.B., V.I.G., P.P., K.D., R.F.S., H.D.), and the Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover (M.H., F.T., A.G.) - both in Germany; the Division of Hematology, Fondazione IRCCS, Istituto Nazionale dei Tumori, and Department of Oncology and Onco-Hematology, University of Milan, Milan (N.B.); the Department of Human Genetics, University of Leuven, Leuven, Belgium (P.V.L.); and the Department of Pathology, University of Otago, Christchurch, New Zealand (P.G., P.J.C.).

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http://dx.doi.org/10.1056/NEJMoa1516192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979995PMC
June 2016

Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.

Epigenetics 2014 Aug 27;9(8):1108-19. Epub 2014 May 27.

Center for Hematology and Regenerative Medicine (HERM); Department of Medicine Huddinge; Karolinska Institute; Stockholm, Sweden; Hematology Centre, M54; Karolinska University Hospital and Karolinska Institute; Stockholm, Sweden.

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http://dx.doi.org/10.4161/epi.29315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164496PMC
August 2014

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

Cancer Discov 2014 Mar 17;4(3):362-75. Epub 2013 Dec 17.

Departments of 1Leukemia, 2Pediatrics, and 3Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; 4Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; 5Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 6The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio; 7AbbVie Inc., North Chicago, Illinois; and 8Department of Laboratory Medicine, University of California San Francisco, San Francisco, California; 9Department of Internal Medicine III, University Hospital of Ulm, Ulm; 10MLL Munich Leukemia Laboratory, Munich, Germany.

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http://research4.dfci.harvard.edu/letai/Publications/2013-12
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http://cancerdiscovery.aacrjournals.org/cgi/doi/10.1158/2159
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http://dx.doi.org/10.1158/2159-8290.CD-13-0609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975047PMC
March 2014

Impact of genetic features on treatment decisions in AML.

Hematology Am Soc Hematol Educ Program 2011 ;2011:36-42

Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1182/asheducation-2011.1.36DOI Listing
April 2012