Publications by authors named "Venturina Stagni"

20Publications

Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma.

Int J Mol Sci 2020 Jul 11;21(14). Epub 2020 Jul 11.

Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/ijms21144910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402284PMC
July 2020

Targeting breast cancer stem-like cells using chloroquine encapsulated by a triphenylphosphonium-functionalized hyperbranched polymer.

Int J Pharm 2020 Jul 1;585:119465. Epub 2020 Jun 1.

Institute of Nanoscience and Nanotechnology, NCSR "Demokritos", 15310 Aghia Paraskevi, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2020.119465DOI Listing
July 2020

Caspase-8: A Novel Target to Overcome Resistance to Chemotherapy in Glioblastoma.

Int J Mol Sci 2018 Nov 29;19(12). Epub 2018 Nov 29.

Department of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.

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http://www.mdpi.com/1422-0067/19/12/3798
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http://dx.doi.org/10.3390/ijms19123798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320982PMC
November 2018

ATM: An unexpected tumor-promoting factor in HER2-expressing tumors.

Mol Cell Oncol 2016 Mar 10;3(2):e1054551. Epub 2015 Jun 10.

Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy; Department of Biology, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/23723556.2015.1054551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905372PMC
March 2016

ATM kinase sustains HER2 tumorigenicity in breast cancer.

Nat Commun 2015 Apr 16;6:6886. Epub 2015 Apr 16.

1] Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, 00179 Rome, Italy [2] Department of Biology, University of Rome 'Tor Vergata', 00133 Rome, Italy.

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http://dx.doi.org/10.1038/ncomms7886DOI Listing
April 2015

ITCH E3 ligase in ATM network.

Oncoscience 2014 4;1(6):394-5. Epub 2014 Jun 4.

Department of Biology, University of Rome "Tor Vergata", Rome, Italy and Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284624PMC
http://dx.doi.org/10.18632/oncoscience.50DOI Listing
January 2015

Tug of war between survival and death: exploring ATM function in cancer.

Int J Mol Sci 2014 Mar 27;15(4):5388-409. Epub 2014 Mar 27.

Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, 00179 Rome, Italy.

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http://dx.doi.org/10.3390/ijms15045388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013570PMC
March 2014

ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition.

J Exp Clin Cancer Res 2013 Nov 19;32:95. Epub 2013 Nov 19.

Experimental Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi, 53-00144 Rome, Italy.

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http://dx.doi.org/10.1186/1756-9966-32-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176289PMC
November 2013

A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.

Cancers (Basel) 2012 Apr 5;4(2):354-78. Epub 2012 Apr 5.

Department of Biology, University of Tor Vergata, Rome 00133, Italy.

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http://dx.doi.org/10.3390/cancers4020354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712690PMC
April 2012

Oxygen sensing is impaired in ATM-defective cells.

Cell Cycle 2011 Dec 15;10(24):4311-20. Epub 2011 Dec 15.

Istituto di Biologia Cellulare e Neurobiologia CNR and IRCCS Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.4161/cc.10.24.18663DOI Listing
December 2011

ATM kinase activity modulates cFLIP protein levels: potential interplay between DNA damage signalling and TRAIL-induced apoptosis.

Carcinogenesis 2010 Nov 27;31(11):1956-63. Epub 2010 Sep 27.

Laboratory of Cell Signaling, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.

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http://dx.doi.org/10.1093/carcin/bgq193DOI Listing
November 2010

Identification of a critical tyrosine residue in caspase 8 that promotes cell migration.

J Biol Chem 2008 May 23;283(19):13031-4. Epub 2008 Jan 23.

Department of Pathology, University of California San Diego School of Medicine, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1074/jbc.M800549200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442311PMC
May 2008

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Blood 2008 Jan 11;111(2):829-37. Epub 2007 Oct 11.

Dulbecco Telethon Institute, Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Italy.

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http://dx.doi.org/10.1182/blood-2007-04-085399DOI Listing
January 2008

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression.

EMBO J 2006 May 13;25(9):1895-905. Epub 2006 Apr 13.

Department of Experimental Medicine and Biochemical Sciences, Dulbecco Telethon Institute, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1038/sj.emboj.7601085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456929PMC
May 2006