Veerle Baekelandt

Veerle Baekelandt

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Veerle Baekelandt

Publications by authors named "Veerle Baekelandt"

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RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits.

Hum Mol Genet 2019 11;28(21):3552-3568

Institute of Parasitology and Biomedicine 'López-Neyra', Consejo Superior de Investigaciones Científicas (CSIC), Avda del Conocimiento s/n, Granada 18016, Spain.

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http://dx.doi.org/10.1093/hmg/ddz201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927464PMC
November 2019

Temporal changes in neuroinflammation and brain glucose metabolism in a rat model of viral vector-induced α-synucleinopathy.

Exp Neurol 2019 10 25;320:112964. Epub 2019 May 25.

Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, University Hospitals Leuven, Leuven, Belgium; MoSAIC - Molecular Small Animal Imaging Centre, KU Leuven, Leuven, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S00144886193011
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http://dx.doi.org/10.1016/j.expneurol.2019.112964DOI Listing
October 2019

Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson's disease.

Acta Neuropathol Commun 2019 10 22;7(1):160. Epub 2019 Oct 22.

KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium.

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http://dx.doi.org/10.1186/s40478-019-0814-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805517PMC
October 2019

Increased P2X7 Receptor Binding Is Associated With Neuroinflammation in Acute but Not Chronic Rodent Models for Parkinson's Disease.

Front Neurosci 2019 31;13:799. Epub 2019 Jul 31.

Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, University Hospital Leuven, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fnins.2019.00799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684733PMC
July 2019

Probing the Mechanisms of Repetition Suppression in Inferior Temporal Cortex with Optogenetics.

Curr Biol 2019 06 6;29(12):1988-1998.e4. Epub 2019 Jun 6.

Laboratory for Neuro- and Psychophysiology, KU Leuven, Leuven 3000, Belgium; Leuven Brain Institute, KU Leuven, Leuven 3000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.05.014DOI Listing
June 2019

Retinal α-synuclein deposits in Parkinson's disease patients and animal models.

Acta Neuropathol 2019 03 5;137(3):379-395. Epub 2019 Feb 5.

Research Group of Neural Circuit Development and Regeneration, Department of Biology, KU Leuven, Naamsestraat 61, Box 2464, Louvain, Belgium.

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http://dx.doi.org/10.1007/s00401-018-01956-zDOI Listing
March 2019

Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine.

Elife 2019 02 12;8. Epub 2019 Feb 12.

Laboratory for Enteric NeuroScience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.7554/eLife.42914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391068PMC
February 2019

RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A.

Front Mol Neurosci 2018 13;11:417. Epub 2018 Nov 13.

Institute of Parasitology and Biomedicine "López-Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.

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http://dx.doi.org/10.3389/fnmol.2018.00417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243087PMC
November 2018

LRRK2 Phosphorylation: Behind the Scenes.

Neuroscientist 2018 10 31;24(5):486-500. Epub 2018 Jan 31.

1 Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1177/1073858418756309DOI Listing
October 2018

Linking Neuroinflammation and Neurodegeneration in Parkinson's Disease.

J Immunol Res 2018 16;2018:4784268. Epub 2018 Apr 16.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1155/2018/4784268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926497PMC
October 2018

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.

Cell 2018 10 30;175(2):400-415.e13. Epub 2018 Aug 30.

Laboratory for Intestinal Neuroimmune Interactions, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, University of Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.048DOI Listing
October 2018

Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia.

Neurobiol Aging 2018 01 21;61:82-92. Epub 2017 Sep 21.

Division of Nuclear Medicine, Department of Imaging and Pathology, KU Leuven and University Hospital Leuven, Leuven, Belgium; MoSAIC - Molecular Small Animal Imaging Centre, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.006DOI Listing
January 2018

Evaluation of WGA-Cre-dependent topological transgene expression in the rodent brain.

Brain Struct Funct 2017 03 3;222(2):717-733. Epub 2016 Jun 3.

Department of Neurosciences, Laboratory for Neurobiology and Gene Therapy, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00429-016-1241-xDOI Listing
March 2017

ɑ-Synuclein strains and the variable pathologies of synucleinopathies.

J Neurochem 2016 10 30;139 Suppl 1:256-274. Epub 2016 Mar 30.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/jnc.13595DOI Listing
October 2016

Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB.

PLoS One 2015 11;10(11):e0142067. Epub 2015 Nov 11.

Neural Circuit Development and Regeneration Research Group, Department of Biology, KU Leuven, Leuven, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142067PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641732PMC
June 2016

α-synuclein folds: the cards are on the table.

Nat Struct Mol Biol 2016 05;23(5):359-60

Department of Neurosciences, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nsmb.3209DOI Listing
May 2016

Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.

Parkinsons Dis 2016 17;2016:9531917. Epub 2016 Mar 17.

Laboratory of Cellular Transport Systems, Department of Cellular and Molecular Medicine, KU Leuven, Campus Gasthuisberg O&N 1, Herestraat 49, P.O. Box 802, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1155/2016/9531917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814700PMC
April 2016

High-content analysis of α-synuclein aggregation and cell death in a cellular model of Parkinson's disease.

J Neurosci Methods 2016 Mar 24;261:117-27. Epub 2015 Nov 24.

KU Leuven, Laboratory for Neurobiology and Gene Therapy, Kapucijnenvoer 33, Leuven B-3000, Flanders, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2015.11.009DOI Listing
March 2016

Noninvasive Imaging Reveals Stable Transgene Expression in Mouse Airways After Delivery of a Nonintegrating Recombinant Adeno-Associated Viral Vector.

Hum Gene Ther 2016 01 21;27(1):60-71. Epub 2015 Dec 21.

1 Laboratory for Molecular Virology and Gene Therapy , Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Flanders, Belgium.

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http://dx.doi.org/10.1089/hum.2015.109DOI Listing
January 2016

Oncostatin M protects against demyelination by inducing a protective microglial phenotype.

Glia 2015 Oct 29;63(10):1729-37. Epub 2015 Apr 29.

Department of Immunology, Biomedical Research Institute, Hasselt University, Diepenbeek, Belgium.

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http://dx.doi.org/10.1002/glia.22840DOI Listing
October 2015

Evaluation of the expression pattern of rAAV2/1, 2/5, 2/7, 2/8, and 2/9 serotypes with different promoters in the mouse visual cortex.

J Comp Neurol 2015 Oct 19;523(14):2019-42. Epub 2015 Jun 19.

KU Leuven, Laboratory of Neuroplasticity and Neuroproteomics, Department of Biology, Leuven, Belgium.

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http://dx.doi.org/10.1002/cne.23819DOI Listing
October 2015

Viral vector-based models of Parkinson's disease.

Curr Top Behav Neurosci 2015 ;22:271-301

Katholieke Universiteit Leuven, Leuven, Belgium,

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http://dx.doi.org/10.1007/7854_2014_310DOI Listing
September 2015

Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.

FASEB J 2015 Jul 8;29(7):2980-92. Epub 2015 Apr 8.

*Novartis Institutes for Biomedical Research, Basel, Switzerland; and Department of Neurosciences, Research Group for Neurobiology and Gene Therapy, Katholieke Universiteit (KU) Leuven, Leuven, Belgium

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http://dx.doi.org/10.1096/fj.14-262329DOI Listing
July 2015

A lipid switch unlocks Parkinson's disease-associated ATP13A2.

Proc Natl Acad Sci U S A 2015 Jul 1;112(29):9040-5. Epub 2015 Jul 1.

Laboratory of Cellular Transport Systems, Department of Cellular and Molecular Medicine, ON1 Campus Gasthuisberg, KU Leuven, B3000 Leuven, Belgium;

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http://dx.doi.org/10.1073/pnas.1508220112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517210PMC
July 2015

Serotype-dependent transduction efficiencies of recombinant adeno-associated viral vectors in monkey neocortex.

Neurophotonics 2015 Jul 1;2(3):031209. Epub 2015 Oct 1.

KU Leuven, Laboratory of Neuro- and Psychophysiology, Department of Neurosciences, O&N2 Herestraat 49 bus 10.21, 3000 Leuven, Belgium; Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, 149 13th street, Charlestown, Massachusetts 02129, United States; Harvard Medical School, Department of Radiology, 149 13th street, Charlestown, Massachusetts 02129, United States.

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http://neurophotonics.spiedigitallibrary.org/data/Journals/N
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http://neurophotonics.spiedigitallibrary.org/article.aspx?do
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http://dx.doi.org/10.1117/1.NPh.2.3.031209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729112PMC
July 2015

Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis.

Cell Stem Cell 2015 May;16(5):488-503

Achucarro Basque Center for Neuroscience, Laida Bidea 205, 48170 Zamudio, Spain; Ikerbasque Foundation, María Díaz de Haro 3, 6(th) Floor, 48013 Bilbao, Spain; University of the Basque Country (UPV/EHU), Barrio Sarrena s/n, 48940 Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443499PMC
May 2015

Leukemia inhibitory factor tips the immune balance towards regulatory T cells in multiple sclerosis.

Brain Behav Immun 2015 Mar 13;45:180-8. Epub 2014 Dec 13.

Department of Immunology, Biomedical Research Institute, Hasselt University, Agoralaan Building C, 3590 Diepenbeek, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2014.11.010DOI Listing
March 2015

FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease.

Neurobiol Aging 2015 Mar 21;36(3):1559-68. Epub 2015 Jan 21.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Flanders, Belgium; Leuven Viral Vector Core, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.01.014DOI Listing
March 2015

IL-10 regulates adult neurogenesis by modulating ERK and STAT3 activity.

Front Cell Neurosci 2015 25;9:57. Epub 2015 Feb 25.

Unit of Brain Ischemia, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona Spain ; Department of Brain Ischemia and Neurodegeneration, Institute of Biomedical Research of Barcelona, Consejo Superior de Investigaciones Científicas, Barcelona Spain.

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http://dx.doi.org/10.3389/fncel.2015.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340210PMC
March 2015

Neurogenesis as a new target for the development of antidepressant drugs.

Curr Pharm Des 2014 ;20(23):3763-75

Achucarro Basque Centre for Neuroscience., Bizkaia Technological Park building 205. 48170 Zamudio, Bizkaia, Spain.

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http://dx.doi.org/10.2174/13816128113196660739DOI Listing
January 2015

Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice.

Neurobiol Aging 2014 Nov 14;35(11):2625-2636. Epub 2014 Jun 14.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.04.032DOI Listing
November 2014

Phosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of Parkinsonism.

Front Genet 2014 7;5:382. Epub 2014 Nov 7.

Department of Neurosciences, Laboratory for Neurobiology and Gene Therapy, KU Leuven Leuven, Belgium.

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http://dx.doi.org/10.3389/fgene.2014.00382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224088PMC
November 2014

Indolinone based LRRK2 kinase inhibitors with a key hydrogen bond.

Bioorg Med Chem Lett 2014 Oct 29;24(19):4630-4637. Epub 2014 Aug 29.

Clemens Schöpf-Institute of Organic Chemistry and Biochemistry, Technische Universität Darmstadt, 64287 Darmstadt, Hessen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.08.049DOI Listing
October 2014

Bioluminescence imaging of stroke-induced endogenous neural stem cell response.

Neurobiol Dis 2014 Sep 27;69:144-55. Epub 2014 May 27.

KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, 3000 Leuven, Flanders, Belgium; KU Leuven, Molecular Small Animal Imaging Center, MOSAIC, KU Leuven, 3000 Leuven, Flanders, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.05.014DOI Listing
September 2014

Loss-of-function rodent models for parkin and PINK1.

J Parkinsons Dis 2011 ;1(3):229-51

Laboratory for Neurobiology and Gene Therapy, Division of Molecular Medicine, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3233/JPD-2011-11041DOI Listing
July 2014

Long-term overexpression of human wild-type and T240R mutant Parkin in rat substantia nigra induces progressive dopaminergic neurodegeneration.

J Neuropathol Exp Neurol 2014 Feb;73(2):159-74

From KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Flanders, Belgium (A-SVR, EL, AVdP, CVdH, VB); and KU Leuven, Leuven Viral Vector Core, (CVdH) Flanders, Belgium.

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http://dx.doi.org/10.1097/NEN.0000000000000039DOI Listing
February 2014

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.

Proc Natl Acad Sci U S A 2014 Feb 7;111(7):2626-31. Epub 2014 Feb 7.

Cell Biology and Gene Expression Section, Computational Biology Core, Laboratory of Neurogenetics, and Molecular Genetics Section, National Institute on Aging/National Institutes of Health, Bethesda, MD 20892.

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http://dx.doi.org/10.1073/pnas.1318306111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932908PMC
February 2014

Viral vectors expressing a single microRNA-based short-hairpin RNA result in potent gene silencing in vitro and in vivo.

J Biotechnol 2014 Jan 16;169:71-81. Epub 2013 Nov 16.

KU Leuven, Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2013.11.004DOI Listing
January 2014

In vitro phosphorylation does not influence the aggregation kinetics of WT α-synuclein in contrast to its phosphorylation mutants.

Int J Mol Sci 2014 Jan 15;15(1):1040-67. Epub 2014 Jan 15.

Laboratory of Biomolecular Dynamics, KU Leuven, Celestijnenlaan 200G, Leuven B-3001, Belgium.

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http://dx.doi.org/10.3390/ijms15011040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907855PMC
January 2014

Local overexpression of interleukin-11 in the central nervous system limits demyelination and enhances remyelination.

Mediators Inflamm 2013 30;2013:685317. Epub 2013 May 30.

Biomedical Research Institute, School of Life Sciences, Hasselt University and Transnational University Limburg, 3590 Diepenbeek, Belgium.

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http://dx.doi.org/10.1155/2013/685317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683504PMC
December 2013

Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle.

Biochem J 2013 Nov;456(1):119-28

*Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1042/BJ20121772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141581PMC
November 2013

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.

Mol Neurodegener 2013 Nov 25;8:44. Epub 2013 Nov 25.

Department of Neurosciences and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Laboratory for Neurobiology and Gene Therapy, Kapucijnenvoer 33, box 7001, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1186/1750-1326-8-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222878PMC
November 2013

Human mesenchymal stem cells overexpressing the IL-33 antagonist soluble IL-1 receptor-like-1 attenuate endotoxin-induced acute lung injury.

Am J Respir Cell Mol Biol 2013 Oct;49(4):552-62

1 Human Molecular Genetics Group, Institut d'Investigació Biomèdica de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1165/rcmb.2012-0406OCDOI Listing
October 2013

Metabolic labeling of leucine rich repeat kinases 1 and 2 with radioactive phosphate.

J Vis Exp 2013 Sep 18(79):e50523. Epub 2013 Sep 18.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven and Leuven Institute for Neuroscience and Disease (LIND).

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http://dx.doi.org/10.3791/50523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923590PMC
September 2013

Levodopa gains psychostimulant-like properties after nigral dopaminergic loss.

Ann Neurol 2013 Jul 6;74(1):140-4. Epub 2013 Aug 6.

Institute of Neurodegenerative Diseases, UMR 5293, F-33000 Bordeaux, France, University of Bordeaux, Bordeaux, France; Institute of Neurodegenerative Diseases, UMR 5293, F-33000 Bordeaux, France, National Center for Scientific Research, Bordeaux, France.

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http://dx.doi.org/10.1002/ana.23881DOI Listing
July 2013

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?

Trends Mol Med 2013 Jun 3;19(6):368-77. Epub 2013 May 3.

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Flanders, Belgium.

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http://dx.doi.org/10.1016/j.molmed.2013.04.002DOI Listing
June 2013

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.

Hum Mol Genet 2013 Feb 2;22(3):608-20. Epub 2012 Nov 2.

Transgenics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/dds470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542867PMC
February 2013

P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.

J Med Chem 2012 Nov 13;55(22):9856-67. Epub 2012 Nov 13.

Laboratory of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

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http://pubs.acs.org/doi/10.1021/jm301060g
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http://dx.doi.org/10.1021/jm301060gDOI Listing
November 2012

Phosphorylation of LRRK2: from kinase to substrate.

Biochem Soc Trans 2012 Oct;40(5):1102-10

Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, and Leuven Research Institute for Neuroscience & Disease (LIND), Katholieke Universiteit Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1042/BST20120128DOI Listing
October 2012

Quantitative evaluation of MRI-based tracking of ferritin-labeled endogenous neural stem cell progeny in rodent brain.

Neuroimage 2012 Aug 1;62(1):367-80. Epub 2012 May 1.

Biomedical NMR Unit, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Leuven, Flanders, Belgium.

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http://dx.doi.org/10.1016/j.neuroimage.2012.04.040DOI Listing
August 2012

Preclinical evaluation of [11C]NE40, a type 2 cannabinoid receptor PET tracer.

Nucl Med Biol 2012 Apr 11;39(3):389-99. Epub 2011 Dec 11.

Laboratory for Radiopharmacy, K.U. Leuven, Leuven, Belgium BE3000.

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http://dx.doi.org/10.1016/j.nucmedbio.2011.09.005DOI Listing
April 2012

Acute versus long-term effects of 6-hydroxydopamine on oxidative stress and dopamine depletion in the striatum of mice.

J Neurosci Methods 2011 Nov 18;202(2):128-36. Epub 2011 Jul 18.

Department of Pharmaceutical Chemistry and Drug Analysis, Center for Neuroscience, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.jneumeth.2011.07.004DOI Listing
November 2011

Kinases as targets for Parkinson's disease: from genetics to therapy.

CNS Neurol Disord Drug Targets 2011 Sep;10(6):724-40

Laboratory for Biomolecular Modelling, Katholieke Universiteit Leuven, Belgium.

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http://dx.doi.org/10.2174/187152711797247858DOI Listing
September 2011

Unraveling the role of peptidyl-prolyl isomerases in neurodegeneration.

Mol Neurobiol 2011 Aug 7;44(1):13-27. Epub 2011 May 7.

Laboratory of Biochemistry, IRC, K.U. Leuven-Kortrijk, Etienne Sabbelaan 53, 8500 Kortrijk, Flanders, Belgium.

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http://dx.doi.org/10.1007/s12035-011-8184-2DOI Listing
August 2011

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.

Bioorg Med Chem 2011 Aug 16;19(15):4499-505. Epub 2011 Jun 16.

Laboratory for Radiopharmacy, IMIR K.U. Leuven, O&N2, Herestraat 49, Bus 821, BE-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.bmc.2011.06.033DOI Listing
August 2011

Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease.

Neurochem Int 2011 Jun 31;58(7):785-93. Epub 2011 Mar 31.

Department of Anatomy and Neurosciences, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.neuint.2011.03.004DOI Listing
June 2011

Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance.

J Cell Sci 2011 Apr 8;124(Pt 7):1115-25. Epub 2011 Mar 8.

Laboratory for Neurobiology and Gene Therapy, Molecular Medicine, Katholieke Universiteit Leuven, 3000 Leuven, Flanders, Belgium.

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http://dx.doi.org/10.1242/jcs.078303DOI Listing
April 2011