Vasundhara Kain

Vasundhara Kain

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Vasundhara Kain

Vasundhara Kain

Publications by authors named "Vasundhara Kain"

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Role of neutrophils in ischemic heart failure.

Pharmacol Ther 2020 Jan 16;205:107424. Epub 2019 Oct 16.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2019.107424DOI Listing
January 2020

Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure.

Mol Metab 2020 Jan 16;31:138-149. Epub 2019 Nov 16.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Alabama, 35294, United States. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920298PMC
January 2020

Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.

Circ Res 2019 Nov 6;125(11):957-968. Epub 2019 Oct 6.

From the Division of Cardiovascular Disease (N.P., G.H., V.K., S.D.P., G.A., P.A.), University of Alabama at Birmingham.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315026DOI Listing
November 2019

Gravin gravitates atherogenesis to atheroprogression in the obesogenic setting.

Am J Physiol Heart Circ Physiol 2019 Oct 13;317(4):H790-H792. Epub 2019 Sep 13.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1152/ajpheart.00508.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843014PMC
October 2019

Inhibition of FPR2 impaired leukocytes recruitment and elicited non-resolving inflammation in acute heart failure.

Pharmacol Res 2019 08 16;146:104295. Epub 2019 Jun 16.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2019.104295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679729PMC
August 2019

Lipoxygenase drives lipidomic and metabolic reprogramming in ischemic heart failure.

Metabolism 2019 Jul 15;96:22-32. Epub 2019 Apr 15.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00260495193007
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http://dx.doi.org/10.1016/j.metabol.2019.04.011DOI Listing
July 2019

Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment.

J Cell Physiol 2019 Apr 7;234(4):3910-3920. Epub 2018 Sep 7.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.

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http://doi.wiley.com/10.1002/jcp.27165
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http://dx.doi.org/10.1002/jcp.27165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317995PMC
April 2019

Pretreatment of carprofen impaired initiation of inflammatory- and overlapping resolution response and promoted cardiorenal syndrome in heart failure.

Life Sci 2019 Feb 28;218:224-232. Epub 2018 Dec 28.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2018.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462225PMC
February 2019

Subacute treatment of carprofen facilitate splenocardiac resolution deficit in cardiac injury.

J Leukoc Biol 2018 12 26;104(6):1173-1186. Epub 2018 Aug 26.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Alabama, USA.

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http://dx.doi.org/10.1002/JLB.3A0618-223RDOI Listing
December 2018

Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium.

Am J Physiol Heart Circ Physiol 2018 11 3;315(5):H1091-H1100. Epub 2018 Aug 3.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham , Birmingham, Alabama.

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http://dx.doi.org/10.1152/ajpheart.00290.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734064PMC
November 2018

Immune responsive resolvin D1 programs myocardial infarction-induced cardiorenal syndrome in heart failure.

FASEB J 2018 07 13;32(7):3717-3729. Epub 2018 Feb 13.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1096/fj.201701173RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998972PMC
July 2018

ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK.

Biochim Biophys Acta Mol Basis Dis 2018 May 27;1864(5 Pt A):1702-1716. Epub 2018 Feb 27.

Department of Biology, Dr. Reddy's Institute of Life Sciences (DRILS), University of Hyderabad Campus, Hyderabad 500046, India. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.02.019DOI Listing
May 2018

Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction.

J Mol Cell Cardiol 2018 05 8;118:70-80. Epub 2018 Mar 8.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940552PMC
May 2018

Comprehensive targeted and non-targeted lipidomics analyses in failing and non-failing heart.

Anal Bioanal Chem 2018 Mar 6;410(7):1965-1976. Epub 2018 Feb 6.

Chimie et Biologie des Membranes et Nanoobjets, University of Bordeaux, CNRS UMR 5248, 146, rue Léo Saignat, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s00216-018-0863-7DOI Listing
March 2018

Splenic leukocytes define the resolution of inflammation in heart failure.

Sci Signal 2018 03 6;11(520). Epub 2018 Mar 6.

Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1126/scisignal.aao1818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145858PMC
March 2018

Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology.

Am J Physiol Heart Circ Physiol 2018 02 3;314(2):H255-H267. Epub 2017 Nov 3.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Alabama.

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http://dx.doi.org/10.1152/ajpheart.00528.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867656PMC
February 2018

Obesity and Cardiometabolic Defects in Heart Failure Pathology.

Compr Physiol 2017 Sep 12;7(4):1463-1477. Epub 2017 Sep 12.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Alabama, USA.

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http://dx.doi.org/10.1002/cphy.c170011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903473PMC
September 2017

Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing.

Am J Physiol Heart Circ Physiol 2017 Jul 14;313(1):H89-H102. Epub 2017 Apr 14.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1152/ajpheart.00040.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538863PMC
July 2017

Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy.

Front Cardiovasc Med 2017 31;4:31. Epub 2017 May 31.

Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.

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http://dx.doi.org/10.3389/fcvm.2017.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449449PMC
May 2017

MicroRNA-712 restrains macrophage pro-inflammatory responses by targeting LRRK2 leading to restoration of insulin stimulated glucose uptake by myoblasts.

Mol Immunol 2017 02 16;82:1-9. Epub 2016 Dec 16.

Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.12.014DOI Listing
February 2017

Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction.

Aging (Albany NY) 2016 10;8(11):2611-2634

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL 35233, USA.

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http://dx.doi.org/10.18632/aging.101077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191859PMC
October 2016

Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation.

Am J Physiol Heart Circ Physiol 2015 Dec 2;309(11):H1827-36. Epub 2015 Oct 2.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama

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http://www.physiology.org/doi/10.1152/ajpheart.00608.2015
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http://dx.doi.org/10.1152/ajpheart.00608.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698380PMC
December 2015

MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts.

Biochimie 2015 Dec 8;119:16-26. Epub 2015 Oct 8.

Department of Biology, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2015.10.004DOI Listing
December 2015

Big eater macrophages dominate inflammation resolution following myocardial infarction.

J Mol Cell Cardiol 2015 Oct 2;87:225-7. Epub 2015 Sep 2.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Alabama, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.08.019DOI Listing
October 2015

Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function.

J Mol Cell Cardiol 2015 Jul 11;84:24-35. Epub 2015 Apr 11.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468047PMC
July 2015

Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction.

Basic Res Cardiol 2014 24;109(6):444. Epub 2014 Sep 24.

Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, 703 19th Street South, Birmingham, AL, 35233, USA.

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http://dx.doi.org/10.1007/s00395-014-0444-7DOI Listing
May 2015

Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction.

Am J Physiol Heart Circ Physiol 2015 Feb 5;308(4):H269-80. Epub 2014 Dec 5.

Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama;

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http://dx.doi.org/10.1152/ajpheart.00604.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329482PMC
February 2015

High glucose-induced Ca2+ overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways.

Biochim Biophys Acta 2012 Jul 28;1820(7):907-20. Epub 2012 Feb 28.

National Centre for Cell Science, Pune University, Maharashtra, India.

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http://dx.doi.org/10.1016/j.bbagen.2012.02.010DOI Listing
July 2012

Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis.

Cardiovasc Diabetol 2011 Nov 4;10:97. Epub 2011 Nov 4.

National Centre for Cell Science, NCCS Complex, Pune University Campus, Ganeshkhind Road, Pune-411007, Maharashtra, India.

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http://dx.doi.org/10.1186/1475-2840-10-97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234183PMC
November 2011

Azelnidipine protects myocardium in hyperglycemia-induced cardiac damage.

Cardiovasc Diabetol 2010 Dec 1;9:82. Epub 2010 Dec 1.

National Centre for Cell Science, NCCS Complex, Pune University Campus, Ganeshkhind Road, Pune 411007, Maharashtra, India.

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http://dx.doi.org/10.1186/1475-2840-9-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004822PMC
December 2010

Cardiotoxicity of calmidazolium chloride is attributed to calcium aggravation, oxidative and nitrosative stress, and apoptosis.

Free Radic Biol Med 2009 Sep 2;47(6):699-709. Epub 2009 Jun 2.

National Centre for Cell Science, NCCS Complex, Pune University Campus, Ganeshkhind, Pune 411007, Maharashtra, India.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849090031
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http://dx.doi.org/10.1016/j.freeradbiomed.2009.05.028DOI Listing
September 2009