Publications by authors named "Vanessa Deschoolmeester"

32Publications

Biomarker recommendation for PD-1/PD-L1 immunotherapy development in pediatric cancer based on digital image analysis of PD-L1 and immune cells.

Authors:
Manuel A Silva Nicolas Triltsch Simon Leis Ivan Kanchev Tze Heng Tan Benjamine Van Peel Marian Van Kerckhoven Vanessa Deschoolmeester Johannes Zimmermann

J Pathol Clin Res 2020 04 10;6(2):124-137. Epub 2020 Jan 10.

Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.

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April 2020

In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.

Authors:
Jolien Van den Bossche Christophe Deben Ines De Pauw Hilde Lambrechts Christophe Hermans Vanessa Deschoolmeester Julie Jacobs Pol Specenier Patrick Pauwels Jan Baptist Vermorken Marc Peeters Filip Lardon An Wouters

Mol Oncol 2019 05 5;13(5):1196-1213. Epub 2019 Apr 5.

Center for Oncological Research (CORE), University of Antwerp, Wilrijk, Belgium.

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May 2019

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation.

Authors:
Julie Jacobs Vanessa Deschoolmeester Karen Zwaenepoel Tal Flieswasser Christophe Deben Jolien Van den Bossche Christophe Hermans Christian Rolfo Marc Peeters Olivier De Wever Filip Lardon Vasiliki Siozopoulou Evelien Smits Patrick Pauwels

Oncoimmunology 2018;7(7):e1440167. Epub 2018 Mar 19.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, Wilrijk, Belgium.

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March 2018

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress.

Authors:
Christophe Deben Vanessa Deschoolmeester Jorrit De Waele Julie Jacobs Jolien Van den Bossche An Wouters Marc Peeters Christian Rolfo Evelien Smits Filip Lardon Patrick Pauwels

Cancers (Basel) 2018 Apr 21;10(4). Epub 2018 Apr 21.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

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April 2018

Mutation and Methylation Analysis of Circulating Tumor DNA Can Be Used for Follow-up of Metastatic Colorectal Cancer Patients.

Authors:
Nele Boeckx Ken Op de Beeck Matthias Beyens Vanessa Deschoolmeester Christophe Hermans Peggy De Clercq Sonia Garrigou Corinne Normand Els Monsaert Konstantinos Papadimitriou Pierre Laurent-Puig Patrick Pauwels Guy Van Camp Valerie Taly Marc Peeters

Clin Colorectal Cancer 2018 06 22;17(2):e369-e379. Epub 2018 Feb 22.

Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium; Department of Oncology, Antwerp University Hospital, Antwerp, Belgium. Electronic address:

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June 2018

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

Authors:
Ines De Pauw Filip Lardon Jolien Van den Bossche Hasan Baysal Erik Fransen Vanessa Deschoolmeester Patrick Pauwels Marc Peeters Jan Baptist Vermorken An Wouters

Mol Oncol 2018 06 1;12(6):830-854. Epub 2018 May 1.

Center for Oncological Research (CORE), University of Antwerp, Wilrijk, Belgium.

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June 2018

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.

Authors:
Julie Jacobs Vanessa Deschoolmeester Christian Rolfo Karen Zwaenepoel Jolien Van den Bossche Christophe Deben Karen Silence Hans de Haard Christophe Hermans Sylvie Rottey Christel Vangestel Filip Lardon Evelien Smits Patrick Pauwels

Oncotarget 2017 Sep 23;8(43):74058-74067. Epub 2017 May 23.

Center for Oncological Research, University of Antwerp, Antwerp, 2610 Wilrijk, Belgium.

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September 2017

Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines.

Authors:
Ines De Pauw An Wouters Jolien Van den Bossche Vanessa Deschoolmeester Hasan Baysal Patrick Pauwels Marc Peeters Jan B Vermorken Filip Lardon

Cancer Biother Radiopharm 2017 Sep;32(7):229-238

1 Center for Oncological Research (CORE), University of Antwerp , Antwerp, Belgium .

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September 2017

SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

Authors:
Christophe Deben Ken Op de Beeck Jolien Van den Bossche Julie Jacobs Filip Lardon An Wouters Marc Peeters Guy Van Camp Christian Rolfo Vanessa Deschoolmeester Patrick Pauwels

J Cancer 2017 15;8(12):2154-2162. Epub 2017 Jul 15.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium.

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July 2017

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the Mutation Status and Hypoxia.

Authors:
Jolien Van den Bossche Christophe Deben Ken Op de Beeck Vanessa Deschoolmeester Christophe Hermans Ines De Pauw Julie Jacobs Paul Van Schil Jan Baptist Vermorken Patrick Pauwels Marc Peeters Filip Lardon An Wouters

J Cancer 2017 12;8(8):1441-1452. Epub 2017 May 12.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.

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May 2017

Deep sequencing of the TP53 gene reveals a potential risk allele for non-small cell lung cancer and supports the negative prognostic value of TP53 variants.

Authors:
Christophe Deben Jolien Van den Bossche Nele Van Der Steen Filip Lardon An Wouters Ken Op de Beeck Christophe Hermans Julie Jacobs Marc Peeters Guy Van Camp Christian Rolfo Vanessa Deschoolmeester Patrick Pauwels

Tumour Biol 2017 Feb;39(2):1010428317694327

1 Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium.

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February 2017

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer.

Authors:
Nele Van Der Steen Christophe Deben Vanessa Deschoolmeester An Wouters Filip Lardon Christian Rolfo Paul Germonpré Elisa Giovannetti Godefridus J Peters Patrick Pauwels

World J Clin Oncol 2016 Dec;7(6):425-432

Nele Van Der Steen, Christophe Deben, Vanessa Deschoolmeester, An Wouters, Filip Lardon, Christian Rolfo, Paul Germonpré, Patrick Pauwels, Center for Oncological Research, University of Antwerp, 2610 Wilrijk, Belgium.

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December 2016

A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.

Authors:
Laure Sorber Karen Zwaenepoel Vanessa Deschoolmeester Geert Roeyen Filip Lardon Christian Rolfo Patrick Pauwels

J Mol Diagn 2017 01 17;19(1):162-168. Epub 2016 Nov 17.

Center for Oncological Research, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium; Department of Pathology, Antwerp University Hospital, Edegem, Belgium. Electronic address:

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January 2017

APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

Authors:
Christophe Deben Filip Lardon An Wouters Ken Op de Beeck Jolien Van den Bossche Julie Jacobs Nele Van Der Steen Marc Peeters Christian Rolfo Vanessa Deschoolmeester Patrick Pauwels

Cancer Lett 2016 Jun 11;375(2):313-322. Epub 2016 Mar 11.

Center for Oncological Research (CORE), University of Antwerp, Universiteitsplein 1 2610 Wilrijk, Antwerp, Belgium; Department of Pathology, Antwerp University Hospital, Wilrijkstraat 10 2650 Edegem, Antwerp, Belgium.

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June 2016

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.

Authors:
Christophe Deben Vanessa Deschoolmeester Filip Lardon Christian Rolfo Patrick Pauwels

Crit Rev Oncol Hematol 2016 Mar 28;99:63-73. Epub 2015 Nov 28.

Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium; Department of Pathology, Antwerp University Hospital, Antwerp, Belgium.

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March 2016

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect.

Authors:
Julie Jacobs Evelien Smits Filip Lardon Patrick Pauwels Vanessa Deschoolmeester

J Immunol Res 2015 29;2015:158038. Epub 2015 Oct 29.

Center for Oncological Research, University of Antwerp, 2610 Wilrijk, Belgium ; Department of Pathology, Antwerp University Hospital, 2650 Edegem, Belgium.

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August 2016

Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.

Authors:
Nele Boeckx Marc Peeters Guy Van Camp Patrick Pauwels Ken Op de Beeck Vanessa Deschoolmeester

Drugs 2015 Oct;75(15):1739-56

Center for Oncological Research Antwerp, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, Wilrijk, 2610, Antwerp, Belgium.

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October 2015

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer.

Authors:
Christophe Deben An Wouters Ken Op de Beeck Jolien van Den Bossche Julie Jacobs Karen Zwaenepoel Marc Peeters Jan Van Meerbeeck Filip Lardon Christian Rolfo Vanessa Deschoolmeester Patrick Pauwels

Oncotarget 2015 Sep;6(26):22666-79

Center for Oncological Research (CORE), University of Antwerp, Antwerp, Belgium.

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September 2015

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer.

Authors:
Julie Jacobs Karen Zwaenepoel Christian Rolfo Jolien Van den Bossche Christophe Deben Karen Silence Christophe Hermans Evelien Smits Paul Van Schil Filip Lardon Vanessa Deschoolmeester Patrick Pauwels

Oncotarget 2015 May;6(15):13462-75

Center for Oncological Research Antwerp, Center for Oncological Research Antwerp (CORE), Antwerp University, Wilrijk, Belgium.

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May 2015

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins.

Authors:
Carolien Boeckx Ken Op de Beeck An Wouters Vanessa Deschoolmeester Ridha Limame Karen Zwaenepoel Pol Specenier Patrick Pauwels Jan B Vermorken Marc Peeters Guy Van Camp Marc Baay Filip Lardon

Cancer Lett 2014 Nov 2;354(2):365-77. Epub 2014 Sep 2.

Center for Oncological Research (CORE) Antwerp, Laboratory of Cancer Research and Clinical Oncology, University of Antwerp, Universiteitsplein1, Wilrijk, Belgium.

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November 2014