Vanessa Almendro

Vanessa Almendro

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Vanessa Almendro

Vanessa Almendro

Publications by authors named "Vanessa Almendro"

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49Publications

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Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.

Mol Oncol 2018 11 21;12(11):1838-1855. Epub 2018 Sep 21.

Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Norway.

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http://doi.wiley.com/10.1002/1878-0261.12375
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http://dx.doi.org/10.1002/1878-0261.12375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210052PMC
November 2018

Histamine receptor 1 inhibition enhances antitumor therapeutic responses through extracellular signal-regulated kinase (ERK) activation in breast cancer.

Cancer Lett 2018 06 14;424:70-83. Epub 2018 Mar 14.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Department of Medicine, University of Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.03.014DOI Listing
June 2018

The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation.

PLoS One 2015 26;10(6):e0129661. Epub 2015 Jun 26.

Department of Medical Oncology, Hospital Clínic, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain; Department of Medicine, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129661PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482606PMC
April 2016

The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women.

Cancer Res 2016 04 3;76(7):1926-34. Epub 2016 Mar 3.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873436PMC
April 2016

Comparison of methods for the isolation of human breast epithelial and myoepithelial cells.

Front Cell Dev Biol 2015 21;3:32. Epub 2015 May 21.

Department of Medical Oncology, Hospital Clínic Barcelona, Spain ; Department of Medicine, University of Barcelona Barcelona, Spain ; Institut d'Investigacions Biomediques August Pi i Sunyer Barcelona, Spain.

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http://dx.doi.org/10.3389/fcell.2015.00032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440402PMC
June 2015

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity.

Nature 2014 Oct 30;514(7520):54-8. Epub 2014 Jul 30.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [4] BBS Program, Harvard Medical School, Boston, Massachusetts 02115, USA [5] Harvard Stem Cell Institute and the Broad Institute, Cambridge, Massachusetts 02138, USA.

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http://dx.doi.org/10.1038/nature13556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184961PMC
October 2014

The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer.

Int J Oncol 2014 Oct 28;45(4):1658-72. Epub 2014 Jul 28.

Institute of Neurosciences of Castilla y León (INCYL), Laboratory of Neuroanatomy of the Peptidergic Systems (Lab. 14), Salamanca, Spain.

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http://dx.doi.org/10.3892/ijo.2014.2565DOI Listing
October 2014

JARID1B is a luminal lineage-driving oncogene in breast cancer.

Cancer Cell 2014 Jun;25(6):762-77

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02141, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.04.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079039PMC
June 2014

Genetic and phenotypic diversity in breast tumor metastases.

Cancer Res 2014 Mar 21;74(5):1338-48. Epub 2014 Jan 21.

Authors' Affiliations: Departments of Medical Oncology and Biostatistics and Computational Biology, Dana-Farber Cancer Institute; Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School; Department of Biostatistics, Harvard School of Public Health, Boston; Departments of Physics and Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Harvard Stem Cell Institute, Cambridge, Massachusetts; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Medical Oncology, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain; Department of Pathology, MizMedi Hospital, Seoul, South Korea; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel; and Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2357-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963810PMC
March 2014

Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.

Cell Rep 2014 Feb 23;6(3):514-27. Epub 2014 Jan 23.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.12.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928845PMC
February 2014

Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer.

Cancer Res 2013 Nov 12;73(21):6424-34. Epub 2013 Sep 12.

Authors' Affiliations: Department of Medical Oncology and Pathology, Hospital Clínic, Institut d'Investigacions Biomediques August Pi i Sunyer, Department of Medicine, University of Barcelona; Department of Cell Biology, Immunology, and Neurosciences, Medical School, University of Barcelona, Barcelona, Spain; Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea; Department of Genetics, Oslo University Hospital Radiumhospitalet, Norway; and Department of Medicine and Experimental Oncology, Torino University, Turin, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4573DOI Listing
November 2013

Cellular heterogeneity and molecular evolution in cancer.

Annu Rev Pathol 2013 Jan 22;8:277-302. Epub 2012 Oct 22.

Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA.

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http://dx.doi.org/10.1146/annurev-pathol-020712-163923DOI Listing
January 2013

Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2.

J Cell Physiol 2012 Apr;227(4):1358-66

Department of Medical Oncology, Hospital Clínic, Medical School, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/jcp.22848DOI Listing
April 2012

Intra-tumour heterogeneity: a looking glass for cancer?

Nat Rev Cancer 2012 Apr 19;12(5):323-34. Epub 2012 Apr 19.

Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston MA 02215, USA.

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http://dx.doi.org/10.1038/nrc3261DOI Listing
April 2012

The neuronal influence on tumor progression.

Biochim Biophys Acta 2011 Dec 14;1816(2):105-18. Epub 2011 May 14.

Department of Medical Oncology, Centro Esther Koplowitz CEK, Institut d' investigacions Biomèdiques August Pi i Sunyer IDIBAPS, Hospital Clinic, Medical School, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbcan.2011.04.005DOI Listing
December 2011

Characterization of human pancreatic orthotopic tumor xenografts suitable for drug screening.

Cell Oncol (Dordr) 2011 Dec 17;34(6):511-21. Epub 2011 Jun 17.

Departament de Bioquímica i Biologia Molecular, Institut de Biomedicina, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1007/s13402-011-0049-1DOI Listing
December 2011

Interleukin-15 affects differentiation and apoptosis in adipocytes: implications in obesity.

Lipids 2011 Nov 6;46(11):1033-42. Epub 2011 Sep 6.

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Cancer Research Group, Universitat de Barcelona, Diagonal 645, 08028, Barcelona, Spain.

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http://doi.wiley.com/10.1007/s11745-011-3594-5
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http://dx.doi.org/10.1007/s11745-011-3594-5DOI Listing
November 2011

Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death.

Cancer Biol Ther 2011 Jan 1;11(1):4-13. Epub 2011 Jan 1.

Department of Medical Oncology, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.4161/cbt.11.1.13672DOI Listing
January 2011

Tyrosine kinase receptor transactivation associated to G protein-coupled receptors.

Curr Drug Targets 2010 Sep;11(9):1169-80

Institut d'Investigacions Biomèdiques Agustí Pi y Sunyer, Laboratory of Molecular and Translational Oncology (ICMHO), University of Barcelona, Casanova 143, 08036 Barcelona, Spain.

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http://dx.doi.org/10.2174/138945010792006807DOI Listing
September 2010

Tumor promoting effects of CD95 signaling in chemoresistant cells.

Mol Cancer 2010 Jun 23;9:161. Epub 2010 Jun 23.

Medical Oncology, Institut d'Investigacions Biomèdiques Agustí Pi y Sunyer (IDIBAPS), Institut Clínic de Malalties Hemato-Oncològiques (ICMHO), Hospital Clínic, Facultat de Medicina, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1186/1476-4598-9-161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906471PMC
June 2010

Interleukin-15 increases calcineurin expression in 3T3-L1 cells: possible involvement on in vivo adipocyte differentiation.

Int J Mol Med 2009 Oct;24(4):453-8

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3892/ijmm_00000252DOI Listing
October 2009

The role of MMP7 and its cross-talk with the FAS/FASL system during the acquisition of chemoresistance to oxaliplatin.

PLoS One 2009 6;4(3):e4728. Epub 2009 Mar 6.

Facultat de Medicina, Hospital Clínic, Institut d'Investigacions Biomèdiques Agustí Pi y Sunyer, Universitat de Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004728PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648894PMC
May 2009

Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs.

Obesity (Silver Spring) 2008 Feb;16(2):285-9

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/oby.2007.47DOI Listing
February 2008

Antiproteolytic effects of plasma from hibernating bears: a new approach for muscle wasting therapy?

Clin Nutr 2007 Oct 27;26(5):658-61. Epub 2007 Sep 27.

Cancer Research Group, Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.clnu.2007.07.003DOI Listing
October 2007

The AP-1/NF-kappaB double inhibitor SP100030 can revert muscle wasting during experimental cancer cachexia.

Int J Oncol 2007 May;30(5):1239-45

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain.

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May 2007

Targets in clinical oncology: the metabolic environment of the patient.

Front Biosci 2007 May 1;12:3024-51. Epub 2007 May 1.

Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.2741/2293DOI Listing
May 2007

Interleukin-15 increases glucose uptake in skeletal muscle. An antidiabetogenic effect of the cytokine.

Biochim Biophys Acta 2006 Nov 12;1760(11):1613-7. Epub 2006 Sep 12.

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbagen.2006.09.001DOI Listing
November 2006

Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load.

Biochim Biophys Acta 2006 Jan 18;1761(1):37-42. Epub 2006 Jan 18.

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.bbalip.2005.12.006DOI Listing
January 2006

Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue.

Int J Oncol 2005 Sep;27(3):855-60

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain.

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September 2005

Interleukin-15 decreases proteolysis in skeletal muscle: a direct effect.

Int J Mol Med 2005 Sep;16(3):471-6

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain.

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September 2005

Interleukin-15 decreases lipid intestinal absorption.

Int J Mol Med 2005 Jun;15(6):963-7

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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June 2005

Cross-talk between skeletal muscle and adipose tissue: a link with obesity?

Med Res Rev 2005 Jan;25(1):49-65

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/med.20010DOI Listing
January 2005

Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake. Involvement of ROS in a model of mouse cancer cachexia.

FEBS Lett 2005 Jan;579(3):717-22

Cancer Research Group, Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.febslet.2004.12.050DOI Listing
January 2005

Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting.

Cancer Res 2004 Sep;64(18):6725-31

Cancer Research Group, Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-04-0425DOI Listing
September 2004

Sepsis induces DNA fragmentation in rat skeletal muscle.

Eur Cytokine Netw 2003 Oct-Dec;14(4):256-9

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain.

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August 2004

Interleukin-15 is able to suppress the increased DNA fragmentation associated with muscle wasting in tumour-bearing rats.

FEBS Lett 2004 Jul;569(1-3):201-6

Departament de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.febslet.2004.05.066DOI Listing
July 2004

Rat liver lipogenesis is modulated by interleukin-15.

Int J Mol Med 2004 Jun;13(6):817-9

Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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June 2004

The pharmacological treatment of cachexia.

Curr Drug Targets 2004 Apr;5(3):265-77

Department de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.2174/1389450043490505DOI Listing
April 2004