Valter Torri

Valter Torri

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Valter Torri

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Assessing assumptions for statistical analyses in randomised clinical trials.

BMJ Evid Based Med 2019 Oct 4;24(5):185-189. Epub 2019 Apr 4.

Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Kobenhavn, Denmark.

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http://dx.doi.org/10.1136/bmjebm-2019-111174DOI Listing
October 2019

Gadoxetate Disodium-Enhanced MR Cholangiography for Evaluation of Biliary-Enteric Anastomoses: Added Value Beyond Conventional T2-Weighted Images.

AJR Am J Roentgenol 2019 09 7;213(3):W123-W133. Epub 2019 May 7.

Laboratory of Methodology for Clinical Research, Istituto di Ricerche Farmacologiche "Mario Negri," Milano, Italy.

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http://dx.doi.org/10.2214/AJR.18.20626DOI Listing
September 2019

Turn off pain evaluates the quality of pain care provided for paediatric inpatients.

Acta Paediatr 2019 01 21;108(1):16-18. Epub 2018 Sep 21.

Vivere Senza Dolore Onlus, Milan, Italy.

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http://doi.wiley.com/10.1111/apa.14562
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http://dx.doi.org/10.1111/apa.14562DOI Listing
January 2019

Assessment of proportional hazard assumption in aggregate data: a systematic review on statistical methodology in clinical trials using time-to-event endpoint.

Br J Cancer 2018 12 13;119(12):1456-1463. Epub 2018 Nov 13.

Laboratory of Methodology for Clinical Research, Oncology Department, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

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http://www.nature.com/articles/s41416-018-0302-8
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http://dx.doi.org/10.1038/s41416-018-0302-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288087PMC
December 2018

The Glaucoma Italian Pediatric Study (GIPSy): 3-Year Results.

J Glaucoma 2018 10;27(10):856-863

Hamilton Glaucoma Center, Shiley Eye Institute and the Department of Ophthalmology, University of California, San Diego, CA.

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http://dx.doi.org/10.1097/IJG.0000000000001038DOI Listing
October 2018

Choosing the Best Chemotherapy Agent to Boost Immune Checkpoint Inhibition Activity.

Cancer Res 2018 10;78(20):5729-5730

Department of Pharmaceutical Sciences, University of Eastern Piedmont, A. Avogadro, Novara, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2245DOI Listing
October 2018

Soluble stroma-related biomarkers of pancreatic cancer.

EMBO Mol Med 2018 08;10(8)

Laboratory of Biology and Treatment of Metastasis, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo and Milan, Italy

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http://dx.doi.org/10.15252/emmm.201708741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079536PMC
August 2018

Brain Gliomas: Multicenter Standardized Assessment of Dynamic Contrast-enhanced and Dynamic Susceptibility Contrast MR Images.

Radiology 2018 06 22;287(3):933-943. Epub 2018 Jan 22.

From the Neuroradiology Unit and CERMAC, Vita-Salute San Raffaele University and IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy (N.A., A. Castellano, M. Cadioli, G.M.C.); Neuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (V.C., A.B., D.A.); Department of Radiology, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy (M.G.); Department of Neuroradiology, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico, Milan, Italy (A. Costa); IRCCS Neuromed, Pozzilli (Isernia), Italy (G.G.); Neuroradiology Unit, C. Mondino National Neurologic Institute, Pavia, Italy (P.V.); Pathology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy (M.R.T.); Methodology for Clinical Research Laboratory, Department of Oncology, IRCCS Mario Negri, Milan, Italy (V.T.); Department of Radiology, Mayo Clinic, Rochester, Minn (B.J.E.); and Department of Neuroscience and Imaging and ITAB-Institute of Advanced Biomedical Technologies, University G. d'Annunzio, Chieti, Italy (M. Caulo).

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http://dx.doi.org/10.1148/radiol.2017170362DOI Listing
June 2018

Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.

N Engl J Med 2018 Mar;378(13):1177-1188

From the Divisions of Medical Oncology (A.G.) and Biomedical Statistics and Informatics (Q.S., J.P.M., L.A.R., D.J.S.), Mayo Clinic, Rochester, MN; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Martino-IST, Genoa (A.F. Sobrero), Ospedale Papa Giovanni XXIII, Bergamo (R.L.), and IRCCS Mario Negri Institute for Pharmacological Research, Milan (V.T.) - all in Italy; Karmanos Cancer Institute, Wayne State University, Detroit (A.F. Shields); National Cancer Center Hospital East, Chiba (T. Yoshino), Yokohama City University School of Medicine, Yokohama (T. Yamanaka), and the University of Tokyo, Tokyo (T.W.) - all in Japan; the Institute of Cancer Sciences, University of Glasgow, Glasgow (J.P.), the University of Oxford, Oxford (R.K.), Christie Hospital, Manchester (M.S.), and University Hospital Southampton, Southampton (T.I.) - all in the United Kingdom; Hôpital Européen Georges-Pompidou, Sorbonne Paris Cite/Paris Descartes University (J.T.), and Saint-Antoine Hospital and Sorbonne Universités, Pierre and Marie Curie University-Paris 6 (T.A.), Paris, and Methodology and Quality of Life Unit, INSERM Unité 1098, Besançon (D.V.) - all in France; the Department of Medical Oncology, University Hospital of Heraklion, Faculty of Medicine, University of Crete, Heraklion (J.S.), and Bioclinic Thessaloniki, Thessaloniki (I.B.) - both in Greece; Dana-Farber Cancer Institute, Boston (J.A.M.); and Duke Cancer Institute, Durham, NC (D.N.).

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http://dx.doi.org/10.1056/NEJMoa1713709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426127PMC
March 2018

Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study.

Sci Rep 2018 01 12;8(1):619. Epub 2018 Jan 12.

Hamilton Glaucoma Center, Shiley Eye Institute, and the Department of Ophthalmology, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1038/s41598-017-19113-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766542PMC
January 2018

The Glaucoma Italian Pediatric Study (GIPSy): 1-Year Results.

J Glaucoma 2017 Nov;26(11):987-994

*Department of Medical and Surgical Specialties Section of Ophthalmology, University of Brescia, Brescia †Laboratory of Methodology for Clinical Research, IRCCS-Institute for Pharmacological research Mario Negri, Milan §Department of Ophthalmology, University of Catania, Catania, Italy ‡Department of Ophthalmology, University of Ioannina, Ioannina, Greece ∥Department of Ophthalmology, Hamilton Glaucoma Center, Shiley Eye Institute, the, University of California, San Diego, CA.

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http://dx.doi.org/10.1097/IJG.0000000000000773DOI Listing
November 2017

A MALT lymphoma prognostic index.

Blood 2017 09 18;130(12):1409-1417. Epub 2017 Jul 18.

Lymphoma Unit, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.

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http://dx.doi.org/10.1182/blood-2017-03-771915DOI Listing
September 2017

Final Results of the IELSG-19 Randomized Trial of Mucosa-Associated Lymphoid Tissue Lymphoma: Improved Event-Free and Progression-Free Survival With Rituximab Plus Chlorambucil Versus Either Chlorambucil or Rituximab Monotherapy.

J Clin Oncol 2017 Jun 29;35(17):1905-1912. Epub 2017 Mar 29.

Emanuele Zucca and Franco Cavalli, Oncology Institute of Southern Switzerland, Bellinzona; Luca Mazzucchelli, Cantonal Institute of Pathology, Locarno, Switzerland; Annarita Conconi, Ospedale degli Infermi, Biella; Giovanni Martinelli, European Institute of Oncology; Liliana Devizzi, Fondazione Istituto Nazionale Tumori; Valter Torri, Mario Negri Institute; Andrés J.M. Ferreri, San Raffaele Scientific Institute; Maurilio Ponzoni, San Raffaele Hospital, Milan; Alessandra Tucci, Spedali Civili, Brescia; Umberto Vitolo, University-Hospital Città della Salute e della Scienza, Turin; Maurizio Martelli, Sapienza University; Stefan Hohaus, Catholic University of the Sacred Heart, Rome; Graziella Pinotti, Fondazione Macchi Hospital, Varese; Caterina Stelitano, Bianchi-Melacrino-Morelli Hospitals, Reggio Calabria; Monica Bellei, University of Modena and Reggio Emilia, Modena, Italy; Reda Bouabdallah, Institut Paoli-Calmettes, Marseille; Gilles Salles, Hospices Civils de Lyon and Université Claude Bernard Lyon-1, Pierre-Benite; Catherine Sebban, Centre Léon Bérard, Lyon; Franck Morschhauser, Claude Huriez Hospital, Lille; Anne Moreau, University Hospital of Nantes, Nantes; Hervé Tilly, Centre Henri Becquerel, Rouen; Corinne Haioun, Henri-Mondor Hospital, Paris Créteil; Corinne Haioun, UPEC, Assistance Publique-Hopitaux de Paris; Catherine Thieblemont, Assistance Publique-Hopitaux de Paris, Hôpital-Saint-Louis, Hematooncology-Université Paris Diderot, Sorbonne Paris-Cité, Paris, France; Ruth Pettengell, St George's University of London, London; Andrew Jack, St James's University Hospital, Leeds; Peter Johnson, Southampton General Hospital, Southampton, United Kingdom; Armando Lopez Guillermo and Elias Campo, Hospital Clinic, Barcelona, Spain; Pierre Zachée, ZNA Stuivenberg, Antwerp; and André Bosly, Mont-Godinne UCL, Yvoir, Belgium.

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http://dx.doi.org/10.1200/JCO.2016.70.6994DOI Listing
June 2017

Stereotactic Body Radiation Therapy for Locally Advanced Pancreatic Cancer: A Systematic Review and Pooled Analysis of 19 Trials.

Int J Radiat Oncol Biol Phys 2017 02 24;97(2):313-322. Epub 2016 Oct 24.

Oncology Unit, Department of Oncology, ASST Bergamo Ovest, Treviglio, Italy.

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http://dx.doi.org/10.1016/j.ijrobp.2016.10.030DOI Listing
February 2017

Non-clinical factors influencing pain intensity in cancer patients: Socio-cultural-economic status, awareness of disease and the relation with the oncologist.

Eur J Intern Med 2016 Sep 5;33:e18-9. Epub 2016 May 5.

Medical Oncology Unit 1, Istituto Oncologico Veneto, IRCCS Padova, AIOM, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2016.04.019DOI Listing
September 2016

Waiting for Godot: Predictive factors for adjuvant treatment of patients with luminal breast cancer.

Breast 2016 Jun 23;27:187-8. Epub 2016 Apr 23.

Laboratory of Methodology for Clinical Research, IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2016.02.002DOI Listing
June 2016

In memoriam: Dr. Irene Claudia Floriani (1964-2016).

Endocrine 2016 Apr 29;52(1):178-9. Epub 2016 Feb 29.

Endocrine Unit, Department of Internal Medicine, ASST "Carlo Poma", Mantua, Italy.

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http://dx.doi.org/10.1007/s12020-016-0891-zDOI Listing
April 2016

ACROSCORE: a new and simple tool for the diagnosis of acromegaly, a rare and underdiagnosed disease.

Clin Endocrinol (Oxf) 2016 Mar 21;84(3):380-5. Epub 2015 Oct 21.

Department of Medical Science, Division of Endocrinology, Diabetology and Metabolism, Città della Salute e della Scienza di Torino, University of Torino, Torino, Italy.

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http://doi.wiley.com/10.1111/cen.12959
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http://dx.doi.org/10.1111/cen.12959DOI Listing
March 2016

Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas.

Clin Cancer Res 2015 Dec 21;21(24):5519-31. Epub 2015 Aug 21.

Department of Oncology, University of Turin Medical School, Turin, Italy. Laboratory of Translational Cancer Medicine, Candiolo Cancer Institute-FPO IRCCS, Turin, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3066DOI Listing
December 2015

Safety of Abiraterone Acetate in Castration-resistant Prostate Cancer Patients With Concomitant Cardiovascular Risk Factors.

Am J Clin Oncol 2015 Oct;38(5):479-82

Departments of *Medical Oncology ‡Urology §Prostate Programme, Fondazione IRCCS Istituto Nazionale dei Tumori †Mario Negri Institute for Pharmacological Research, Milan, Italy.

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http://dx.doi.org/10.1097/COC.0b013e3182a790ceDOI Listing
October 2015

Oral prevalence and clearance of oncogenic human papilloma virus in a rehabilitation community for substance abusers in Italy: a case of behavioral correction?

J Oral Pathol Med 2015 Oct 17;44(9):728-33. Epub 2014 Nov 17.

Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1111/jop.12291DOI Listing
October 2015

EGFR mutations and EGFR tyrosine kinase inhibitors.

Lancet Oncol 2015 Jul 4;16(7):746-8. Epub 2015 Jun 4.

Thoracic Oncology, Medical Oncology Department 1, Fondazione IRCCS Istituto Nazionale dei Tumori, 20129 Milano. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00028-5DOI Listing
July 2015

Efficacy of biological agents in metastatic triple-negative breast cancer.

Cancer Treat Rev 2014 Jun 4;40(5):605-13. Epub 2014 Feb 4.

Department of Oncology, Fatebenefratelli e Oftalmico, Corso di Porta Nuova, 23, 20121 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2014.01.003DOI Listing
June 2014

Targeted therapies in advanced renal cell carcinoma: the role of metastatic sites as a prognostic factor.

Future Oncol 2014 Jun;10(8):1361-72

Medical Oncology 1, Fondazione IRCCS, Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.2217/fon.14.69DOI Listing
June 2014

The impact of personalized medicine on survival: comparisons of results in metastatic breast, colorectal and non-small-cell lung cancers.

Cancer Treat Rev 2014 May 25;40(4):485-94. Epub 2013 Sep 25.

Department of Medical Oncology, National Cancer Research Center Giovanni Paolo II, Bari, Italy.

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http://dx.doi.org/10.1016/j.ctrv.2013.09.012DOI Listing
May 2014

Sequential Tyrosine Kinase Inhibitors (TKIs) in metastatic renal cell carcinoma: results from a large cohort of patients.

Anticancer Res 2014 May;34(5):2395-8

Medical Oncology 1, Fondazione IRCCS Istituto Nazionale Tumori Via Venezian 1, 20133 Milan, Italy.

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May 2014

DRAGO (KIAA0247), a new DNA damage-responsive, p53-inducible gene that cooperates with p53 as oncosuppressor. [Corrected].

J Natl Cancer Inst 2014 Apr 20;106(4):dju053. Epub 2014 Mar 20.

Affiliations of authors: Laboratory of Molecular Pharmacology (FP, PR, SZ, FM, MBo, AM, SM, MBr), and Laboratory of Methodology for Biomedical Research (VT), Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy; Dipartimento di Patologia Animale, Igiene e Sanità Pubblica Veterinaria, Università degli Studi di Milano, Milan, Italy (VC, ES); Mouse and Animal Pathology Laboratory, Fondazione Filarete, Milan, Italy (VC, ES); Present address: Laboratory of Genome Integrity, National Cancer Institute, National Institutes of Health, Bethesda, MD (FP).

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http://dx.doi.org/10.1093/jnci/dju053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988459PMC
April 2014

Do we really need another epidermal growth factor receptor tyrosine kinase inhibitor in first-line treatment for patients with non-small-cell lung cancer and EGFR mutations?

J Clin Oncol 2014 Mar 3;32(8):859-63. Epub 2014 Feb 3.

Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1200/JCO.2013.52.8794DOI Listing
March 2014

Does surgery improve survival of patients with malignant pleural mesothelioma?: a multicenter retrospective analysis of 1365 consecutive patients.

J Thorac Oncol 2014 Mar;9(3):390-6

*Department of Thoracic Surgery, Ospedale Civili Brescia, Brescia, Italy; †Department of Thoracic Surgery, Ospedale Maggiore Novara, Novara, Italy; ‡Department of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; §Department of Thoracic Surgery, San Luigi Hospital, Orbassano, Torino, Italy; ‖Department of Thoracic Surgery, Ospedale Policlinico, Milan, Italy; ¶Department of Thoracic Surgery, IRCCS Azienda Ospedaliera Universitaria San Martino, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy; #Department of Thoracic Surgery, Ospedale San Gerardo, Monza, Italy; and **Laboratory of Methodology for Biomedical Research, Oncology Department, IRCCS, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000064DOI Listing
March 2014

Afatinib for lung cancer: let there be light?

Lancet Oncol 2014 Feb 15;15(2):133-4. Epub 2014 Jan 15.

Laboratory of Methodology of Biomedical Research, IRCCS Mario Negri, Milan, Italy.

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http://dx.doi.org/10.1016/S1470-2045(14)70002-6DOI Listing
February 2014

The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.

Acta Ophthalmol 2013 Dec 25;91(8):e612-9. Epub 2013 May 25.

Department of Ophthalmology, University Medical Center Mainz, Mainz, GermanyDepartment of Ophthalmology, University of Milan, Monza, ItalyLeuven University Hospitals, Leuven, BelgiumInstitute Mario Negri, Milan, ItalyDepartment of Ophthalmology, Coimbra University Hospital, Coimbra, Portugal.

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http://dx.doi.org/10.1111/aos.12180DOI Listing
December 2013

ALDH enzymatic activity and CD133 positivity and response to chemotherapy in ovarian cancer patients.

Am J Cancer Res 2013 3;3(2):221-9. Epub 2013 Apr 3.

Department of Oncology, Istituto di Ricerche Farmacologiche "Mario Negri"- IRCCS Via La Masa 19, 20156 Milan, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623840PMC
April 2013

To target or not to target, that is the question.

J Clin Oncol 2013 Mar 28;31(9):1254. Epub 2013 Jan 28.

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http://dx.doi.org/10.1200/JCO.2012.45.9818DOI Listing
March 2013

Meta-analysis on the effects of octreotide on tumor mass in acromegaly.

PLoS One 2012 4;7(5):e36411. Epub 2012 May 4.

Department of Medical and Surgical Sciences, University of Brescia, Montichiari Hospital, Brescia, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036411PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344864PMC
September 2012

Evidence-based guidelines: Improving AGREEment on consistence evaluation.

J Bone Oncol 2012 Jun 30;1(1):30-4. Epub 2012 Apr 30.

University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.

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http://dx.doi.org/10.1016/j.jbo.2012.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723325PMC
June 2012

Dipyridamole stress echocardiography in diagnosis and prognosis of hemodialysis patients with asymptomatic coronary disease.

Hemodial Int 2011 Oct 26;15(4):468-76. Epub 2011 Jul 26.

Dipartimento di Medicina Clinica e Prevenzione, Università degli Studi di Milano Bicocca, Milan, Italy.

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http://dx.doi.org/10.1111/j.1542-4758.2011.00572.xDOI Listing
October 2011

Antibiotics versus surgery for appendicitis.

Lancet 2011 Sep;378(9796):1067-8; author reply 1068

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http://dx.doi.org/10.1016/S0140-6736(11)61471-2DOI Listing
September 2011