Valerio De Stefano

Valerio De Stefano

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Valerio De Stefano

Publications by authors named "Valerio De Stefano"

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Epidemiology of Budd-Chiari syndrome: A systematic review and meta-analysis.

Clin Res Hepatol Gastroenterol 2019 Aug 7;43(4):468-474. Epub 2018 Dec 7.

Department of Gastroenterology, Northern Theater Command General Hospital (formerly General Hospital of Shenyang Military Area), Shenyang, Liaoning Province 110840, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2018.10.014DOI Listing
August 2019

Nonselective beta-blockers and development of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis.

Hepatol Int 2019 Jul 7;13(4):468-481. Epub 2019 Jun 7.

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Northern Theater Command (Formerly Called General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, 110840, Liaoning, China.

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http://dx.doi.org/10.1007/s12072-019-09951-6DOI Listing
July 2019

Identification of novel mutations in patients with fibrinogen disorders and genotype/phenotype correlations.

Blood Transfus 2019 05 8;17(3):247-254. Epub 2018 Oct 8.

Atherosclerosis and Thrombosis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo (Foggia), Italy.

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http://dx.doi.org/10.2450/2018.0123-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596374PMC
May 2019

Remission of acquired von Willebrand syndrome in a patient with chronic lymphocytic leukemia treated with venetoclax.

Leuk Lymphoma 2019 May 20:1-3. Epub 2019 May 20.

a Institute of Hematology , Fondazione Policlinico Universitario A Gemelli IRCCS , Rome , Italy.

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http://dx.doi.org/10.1080/10428194.2019.1612063DOI Listing
May 2019

Prognostic significance of normalized FDG-PET parameters in patients with multiple myeloma undergoing induction chemotherapy and autologous hematopoietic stem cell transplantation: a retrospective single-center evaluation.

Eur J Nucl Med Mol Imaging 2019 01 27;46(1):116-128. Epub 2018 Jul 27.

Istituto di Medicina Nucleare, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, Rome, Italy.

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http://link.springer.com/10.1007/s00259-018-4108-y
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http://dx.doi.org/10.1007/s00259-018-4108-yDOI Listing
January 2019

Indications and use of therapeutic phlebotomy in polycythemia vera: which role for erythrocytapheresis?

Leukemia 2019 01 5;33(1):279-281. Epub 2018 Dec 5.

Fondazione Policlinico Universitario A. Gemelli IRCCS and Istituto di Ematologia, Università Cattolica, Roma, Italy.

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http://dx.doi.org/10.1038/s41375-018-0304-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326952PMC
January 2019

Targeting myeloid cells to prevent recurrent stroke in general population: the lesson of hydroxyurea in myeloproliferative neoplasms.

Blood Cancer J 2018 11 7;8(11):103. Epub 2018 Nov 7.

Fondazione Policlinico Universitario A. Gemelli IRCCS, and Istituto di Ematologia, Università Cattolica del Sacro Cuore, Roma, Italy.

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http://www.nature.com/articles/s41408-018-0143-y
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http://dx.doi.org/10.1038/s41408-018-0143-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221886PMC
November 2018

Different effect of hydroxyurea and phlebotomy on prevention of arterial and venous thrombosis in Polycythemia Vera.

Blood Cancer J 2018 11 26;8(12):124. Epub 2018 Nov 26.

Department of Experimental and Clinical Medicine, Center of Research and Innovation of Myeloproliferative neoplasms (CRIMM), AOU Careggi, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1038/s41408-018-0161-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255832PMC
November 2018

Arterial thrombosis and cancer: the neglected side of the coin of Trousseau syndrome.

Haematologica 2018 09;103(9):1419-1421

Fondazione Policlinico Universitario A. Gemelli IRCCS, Istituto di Ematologia, Università Cattolica, Roma, Italia

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http://dx.doi.org/10.3324/haematol.2018.197814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119149PMC
September 2018

Prevalence of CALR mutations in splanchnic vein thrombosis: A systematic review and meta-analysis.

Thromb Res 2018 07 8;167:96-103. Epub 2018 May 8.

Meta-Analysis Interest Group & Liver Cirrhosis Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.05.007DOI Listing
July 2018

A STARD-compliant prediction model for diagnosing thrombotic microangiopathies.

J Nephrol 2018 06 20;31(3):405-410. Epub 2018 Jan 20.

Divisione di Nefrologia, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Via G. Moscati 31, 00168, Rome, Italy.

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http://dx.doi.org/10.1007/s40620-018-0468-4DOI Listing
June 2018

Risk factors for venous thromboembolism in patients with lymphoma requiring hospitalization.

Blood Cancer J 2018 06 7;8(6):54. Epub 2018 Jun 7.

Institute of Hematology, IRCCS Policlinico Gemelli Foundation, Catholic University of the Sacred Heart, Rome, Italy.

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http://dx.doi.org/10.1038/s41408-018-0096-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993802PMC
June 2018

Antithrombotic therapy for venous thromboembolism in myeloproliferative neoplasms.

Blood Cancer J 2018 06 26;8(7):65. Epub 2018 Jun 26.

FROM Research Foundation, ASST Papa Giovanni XXIII, Bergamo, Italy.

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http://dx.doi.org/10.1038/s41408-018-0101-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018810PMC
June 2018

Splanchnic vein thrombosis in myeloproliferative neoplasms: treatment algorithm 2018.

Blood Cancer J 2018 06 26;8(7):64. Epub 2018 Jun 26.

FROM Research Foundation, ASST Papa Giovanni XXIII, Bergamo, Italy.

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http://dx.doi.org/10.1038/s41408-018-0100-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018786PMC
June 2018

Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure.

Transl Gastroenterol Hepatol 2017 12;2:71. Epub 2017 Sep 12.

Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang 110840, China.

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http://dx.doi.org/10.21037/tgh.2017.08.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639022PMC
September 2017

Management of venous thromboembolism in myeloproliferative neoplasms.

Curr Opin Hematol 2017 03;24(2):108-114

aFROM Research Foundation, Ospedale Papa Giovanni XXIII, Bergamo bInstitute of Hematology, Catholic University, Rome, Italy.

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http://Insights.ovid.com/crossref?an=00062752-201703000-0000
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http://dx.doi.org/10.1097/MOH.0000000000000312DOI Listing
March 2017

Improved Detection of Minimal Residual Disease by 11C-Methionine PET/CT in a Young Patient With Unusual Extramedullary Presentation of Recurrent Multiple Myeloma.

Clin Nucl Med 2017 Feb;42(2):e130-e134

From the Institutes of *Nuclear Medicine, and †Hematology, Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1097/RLU.0000000000001462DOI Listing
February 2017

Thrombocytosis in a patient with upper gastrointestinal bleeding.

Intractable Rare Dis Res 2017 Feb;6(1):69-71

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China.

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http://dx.doi.org/10.5582/irdr.2016.01080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359359PMC
February 2017

Anticoagulation with intravenous unfractionated heparin and major bleeding in cirrhosis.

Hepatology 2016 12 25;64(6):2269-2270. Epub 2016 Aug 25.

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China.

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http://dx.doi.org/10.1002/hep.28743DOI Listing
December 2016

Quality of anticoagulation and outcome of bleeding in cirrhosis.

Hepatology 2016 07 12;64(1):320-1. Epub 2016 Jan 12.

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China.

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http://dx.doi.org/10.1002/hep.28369DOI Listing
July 2016

Epidemiology, Risk Factors, and In-Hospital Mortality of Venous Thromboembolism in Liver Cirrhosis: A Single-Center Retrospective Observational Study.

Med Sci Monit 2016 Mar 24;22:969-76. Epub 2016 Mar 24.

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, Liaoning, China (mainland).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809389PMC
http://dx.doi.org/10.12659/msm.896153DOI Listing
March 2016

Splanchnic vein thrombosis and myeloproliferative neoplasms: molecular-driven diagnosis and long-term treatment.

Thromb Haemost 2016 Jan 3;115(2):240-9. Epub 2015 Sep 3.

Valerio De Stefano, MD, Institute of Hematology, Catholic University, Largo Gemelli 8, 00168 Rome, Italy, Tel.: +39 06 30154968, Fax: +39 06 30155209, E-mail:

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http://dx.doi.org/10.1160/TH15-04-0326DOI Listing
January 2016

Splanchnic Vein Thrombosis: Etiology, Diagnosis, and Treatment.

Gastroenterol Res Pract 2015 25;2015:506136. Epub 2015 Oct 25.

Epatologia e Gastroenterologia, Ospedale Niguarda Cà Granda, Piazza Ospedale Maggiore 3, 20162 Milano, Italy ; Medicina Interna 1, Azienda di Rilievo Nazionale ad Alta Specializzazione Civico-Di Cristina-Benfratelli, Piazzale Liotti 4, 90100 Palermo, Italy.

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http://dx.doi.org/10.1155/2015/506136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637062PMC
November 2015

Thrombopoietin receptor agonists significantly increase the risk of portal vein thrombosis in liver diseases: Meta-analysis of RCTs.

Thromb Haemost 2015 Jun 12;113(6):1378-80. Epub 2015 Mar 12.

Prof. Xiaozhong Guo, MD PhD, Department of Gastroenterology, General Hospital of Shenyang Military Area, No. 83 Wenhua Road, Shenyang, 110840 China, Tel.: +86 24 28897603, Fax: +86 24 28851113, E-mail:

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http://dx.doi.org/10.1160/TH14-10-0892DOI Listing
June 2015

Venous thromboembolism in patients with liver diseases.

Intern Emerg Med 2015 Jun 13;10(4):489-91. Epub 2015 Mar 13.

Institute of Hematology, Catholic University, Rome, Italy,

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http://dx.doi.org/10.1007/s11739-015-1215-7DOI Listing
June 2015

Haemostatic alterations induced by treatment with asparaginases and clinical consequences.

Thromb Haemost 2015 Feb 23;113(2):247-61. Epub 2014 Oct 23.

Valerio De Stefano, MD, Institute of Hematology, Catholic University, Largo Gemelli 8, 00168 Rome, Italy, Tel.: +39 06 30154968, Fax: +39 06 30155209, E-mail:

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http://dx.doi.org/10.1160/TH14-04-0372DOI Listing
February 2015

Anticoagulation for the treatment of portal vein thrombosis in liver cirrhosis: a systematic review and meta-analysis of observational studies.

Eur J Intern Med 2015 Jan 5;26(1):23-9. Epub 2015 Jan 5.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09536205140035
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http://dx.doi.org/10.1016/j.ejim.2014.12.002DOI Listing
January 2015

Associations of antiphospholipid antibodies with splanchnic vein thrombosis: a systematic review with meta-analysis.

Medicine (Baltimore) 2015 Jan;94(4):e496

From the Department of Gastroenterology (XQ, XG), General Hospital of Shenyang Military Area, Shenyang; Xijing Hospital of Digestive Diseases (XQ, MB, DF), Fourth Military Medical University, Xi'an, China; Institute of Hematology (VDS), Catholic University, Rome, Italy; and Library of Fourth Military Medical University (CS), Xi'an, China.

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http://dx.doi.org/10.1097/MD.0000000000000496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602955PMC
January 2015

Methylenetetrahydrofolate reductase C677T gene mutation and hyperhomocysteinemia in Budd-Chiari syndrome and portal vein thrombosis: A systematic review and meta-analysis of observational studies.

Hepatol Res 2014 Dec 20;44(14):E480-98. Epub 2014 May 20.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China; Department of Gastroenterology, no. 463 Hospital of Chinese PLA, Shenyang, China.

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http://dx.doi.org/10.1111/hepr.12348DOI Listing
December 2014

Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd-Chiari syndrome and portal vein thrombosis: a systematic review and meta-analysis.

Clin Gastroenterol Hepatol 2014 Nov 30;12(11):1801-12.e7. Epub 2014 Apr 30.

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2014.04.026DOI Listing
November 2014

Haemoglobin levels in autoimmune haemolytic anaemias at diagnosis: relationship with immunoproteins on red blood cells.

Immunol Res 2014 Oct;60(1):127-31

Transfusion Centre, Institute of Hematology, Catholic University, Rome, Italy,

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http://dx.doi.org/10.1007/s12026-014-8497-0DOI Listing
October 2014

Evaluation of the prevalence of severe hyperhomocysteinemia in adult patients with thrombosis who underwent screening for thrombophilia.

Thromb Res 2013 16;132(6):681-4. Epub 2013 Oct 16.

Medicina III, Azienda Ospedaliera San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2013.09.038DOI Listing
September 2014

Cerebral venous thrombosis and myeloproliferative neoplasms: results from two large databases.

Thromb Res 2014 Jul 29;134(1):41-3. Epub 2014 Mar 29.

Division of Hematology, Department of Internal Medicine, Ospedale di Circolo & Fondazione Macchi, Varese, Italy.

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http://dx.doi.org/10.1016/j.thromres.2014.03.040DOI Listing
July 2014

Reply: Interaction between inherited thrombophilia and HIV infection: fact or fancy?

Nat Rev Cardiol 2014 Jun 8;11(6):321. Epub 2014 Apr 8.

Scientific Direction, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via F. Sforza 28, 20122 Milan, Italy.

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http://dx.doi.org/10.1038/nrcardio.2013.211-c2DOI Listing
June 2014

Myeloid sarcoma with megakaryoblastic differentiation mimicking a sellar tumor.

Neuropathology 2014 Apr 30;34(2):179-84. Epub 2013 Sep 30.

Department of Anatomic Pathology, Catholic University, Rome, Italy.

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http://dx.doi.org/10.1111/neup.12071DOI Listing
April 2014

Venous thromboembolism in multiple myeloma.

Semin Thromb Hemost 2014 Apr 5;40(3):338-47. Epub 2014 Mar 5.

Institute of Hematology, Department of Medical Sciences, Catholic University, Rome, Italy.

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http://dx.doi.org/10.1055/s-0034-1370793DOI Listing
April 2014

Risk factor and etiology analysis of ischemic stroke in young adult patients.

J Stroke Cerebrovasc Dis 2014 Mar 11;23(3):e221-7. Epub 2014 Jan 11.

Department of Neurology, Institute of Neurology, Campus Bio-Medico University, Rome, Italy; Fondazione Alberto Sordi, Research Institute for Ageing, Rome, Italy.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2013.10.008DOI Listing
March 2014

Inherited risk factors for venous thromboembolism.

Nat Rev Cardiol 2014 Mar 14;11(3):140-56. Epub 2014 Jan 14.

Scientific Direction, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via F. Sforza 28, 20122 Milan, Italy.

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http://dx.doi.org/10.1038/nrcardio.2013.211DOI Listing
March 2014

Scientific publications on portal vein thrombosis and Budd-Chiari syndrome: a global survey of the literature.

J Gastrointestin Liver Dis 2014 Mar;23(1):65-71

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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March 2014

Autoimmune hemolytic anemia with gel-based immunohematology tests: neural network analysis.

Immunol Res 2014 Jan;58(1):70-4

Internal Medicine Department, Transfusion Centre, Catholic University, Largo A. Gemelli 8, 00168, Rome, Italy,

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http://dx.doi.org/10.1007/s12026-013-8480-1DOI Listing
January 2014

Are MPNs vascular diseases?

Curr Hematol Malig Rep 2013 Dec;8(4):307-16

Division of Hematology, Ospedale Papa Giovanni XXIII, Piazza OMS, 1, 24127, Bergamo, BG, Italy,

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http://dx.doi.org/10.1007/s11899-013-0176-zDOI Listing
December 2013

Testing for inherited thrombophilia and consequences for antithrombotic prophylaxis in patients with venous thromboembolism and their relatives. A review of the Guidelines from Scientific Societies and Working Groups.

Thromb Haemost 2013 Oct 11;110(4):697-705. Epub 2013 Jul 11.

Valerio De Stefano, MD, Institute of Hematology, Catholic University, Largo Gemelli 8, 00168 Rome, Italy, Tel.: +39 06 30154968, Fax: +39 06 30154206, E-mail:

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http://dx.doi.org/10.1160/TH13-01-0011DOI Listing
October 2013

Influence of proband's characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms.

Blood 2013 Oct 2;122(15):2555-61. Epub 2013 Aug 2.

A. Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Medicine and Medical Specialties, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and University of Milan, Milan, Italy;

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http://dx.doi.org/10.1182/blood-2013-05-503649DOI Listing
October 2013

Platelet activation and inhibition in polycythemia vera and essential thrombocythemia.

Blood 2013 Mar 18;121(10):1701-11. Epub 2013 Jan 18.

Department of Pharmacology, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1182/blood-2012-10-429134DOI Listing
March 2013

Causes of adult splanchnic vein thrombosis in the mediterranean area.

Mediterr J Hematol Infect Dis 2011 19;3(1):e2011063. Epub 2011 Dec 19.

Institute of Hematology, Catholic University, Rome, Italy.

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http://dx.doi.org/10.4084/MJHID.2011.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248340PMC
October 2012

Cerebral sinus-venous thrombosis.

Intern Emerg Med 2012 Oct;7 Suppl 3:S221-5

Department of Internal Medicine and Medical Specialities, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Pace, 9, 20122, Milan, Italy.

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http://dx.doi.org/10.1007/s11739-012-0806-9DOI Listing
October 2012

Abdominal thromboses of splanchnic, renal and ovarian veins.

Best Pract Res Clin Haematol 2012 Sep 11;25(3):253-64. Epub 2012 Aug 11.

Institute of Hematology, Catholic University, Largo Gemelli, Rome, Italy.

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http://dx.doi.org/10.1016/j.beha.2012.07.002DOI Listing
September 2012

Extra-abdominal venous thromboses at unusual sites.

Best Pract Res Clin Haematol 2012 Sep 11;25(3):265-74. Epub 2012 Aug 11.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Internal Medicine and Medical Specialities, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15216926120006
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http://dx.doi.org/10.1016/j.beha.2012.07.003DOI Listing
September 2012

Efficacy of lenalidomide plus dexamethasone for POEMS syndrome relapsed after autologous peripheral stem-cell transplantation.

Am J Hematol 2012 Jun 10;87(6):641-2. Epub 2012 Apr 10.

Department of Hematology, Catholic University of the Sacred Heart, Hospital A. Gemelli, Largo A. Gemelli 8, Rome, Italy.

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http://dx.doi.org/10.1002/ajh.23195DOI Listing
June 2012

Splanchnic vein thrombosis: clinical presentation, risk factors and treatment.

Intern Emerg Med 2010 Dec 8;5(6):487-94. Epub 2010 Jun 8.

Institute of Hematology, Catholic University, Largo Gemelli 8, 00168 Rome, Italy.

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http://dx.doi.org/10.1007/s11739-010-0413-6DOI Listing
December 2010

Rare thromboses of cerebral, splanchnic and upper-extremity veins. A narrative review.

Thromb Haemost 2010 Jun 29;103(6):1136-44. Epub 2010 Mar 29.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Maggiore Hospital, Mangiagalli and Regina Elena Foundation, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1160/TH09-12-0873DOI Listing
June 2010