Publications by authors named "Valerie Reinke"

67Publications

Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression.

BMC Genomics 2019 Jun 17;20(1):500. Epub 2019 Jun 17.

Department of Genetics, Yale University, New Haven, CT, 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-019-5893-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580472PMC
June 2019

The Germline-Specific Factor OEF-1 Facilitates Coordinated Progression Through Germ Cell Development in .

Genetics 2018 02 22;208(2):549-563. Epub 2017 Nov 22.

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.117.1123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788521PMC
February 2018

A Systematic RNAi Screen Reveals a Novel Role of a Spindle Assembly Checkpoint Protein BuGZ in Synaptic Transmission in .

Front Mol Neurosci 2017 11;10:141. Epub 2017 May 11.

Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Department of Neurobiology, Institute of Neuroscience, Zhejiang University School of MedicineHangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnmol.2017.00141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425591PMC
May 2017

The time-resolved transcriptome of C. elegans.

Genome Res 2016 10 16;26(10):1441-1450. Epub 2016 Aug 16.

Department of Genome Sciences, School of Medicine, University of Washington, Seattle, Washington 98195, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.202663.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052054PMC
October 2016

Single cell analysis in C. elegans.

Authors:
Valerie Reinke

Genesis 2016 Apr;54(4):150

Department of Genetics, Yale University, New Haven, CT, 06520.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dvg.22933DOI Listing
April 2016

The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance.

Dev Cell 2014 Oct;31(2):145-58

Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2014.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223638PMC
October 2014

Comparative analysis of the transcriptome across distant species.

Nature 2014 Aug;512(7515):445-8

1] Department of Genome Sciences and University of Washington School of Medicine, William H. Foege Building S350D, 1705 Northeast Pacific Street, Box 355065 Seattle, Washington 98195-5065, USA [2].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155737PMC
August 2014

Insulin/IGF1 signaling inhibits age-dependent axon regeneration.

Neuron 2014 Feb 16;81(3):561-73. Epub 2014 Jan 16.

Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2013.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924874PMC
February 2014

Homeland security in the C. elegans germ line: insights into the biogenesis and function of piRNAs.

Epigenetics 2014 Jan 22;9(1):62-74. Epub 2013 Oct 22.

Department of Genetics; Yale University; New Haven, CT USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.26647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928187PMC
January 2014

Transcriptional regulation of gene expression in C. elegans.

WormBook 2013 Jun 4:1-34. Epub 2013 Jun 4.

Department of Genetics, Yale University, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1895/wormbook.1.45.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893038PMC
June 2013

SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair.

Proc Natl Acad Sci U S A 2011 Aug 18;108(31):12805-10. Epub 2011 Jul 18.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1102298108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150895PMC
August 2011

Extrinsic and intrinsic control of germ cell proliferation in Caenorhabditis elegans.

Mol Reprod Dev 2011 Mar 17;78(3):151-60. Epub 2011 Feb 17.

Department of Genetics, Yale University, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrd.21289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375679PMC
March 2011

C. elegans meg-1 and meg-2 differentially interact with nanos family members to either promote or inhibit germ cell proliferation and survival.

Genesis 2011 May;49(5):380-91

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dvg.20726DOI Listing
May 2011

The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis.

Mech Dev 2011 Mar-Apr;128(3-4):178-90. Epub 2011 Jan 26.

Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mod.2011.01.004DOI Listing
August 2011

A widespread distribution of genomic CeMyoD binding sites revealed and cross validated by ChIP-Chip and ChIP-Seq techniques.

PLoS One 2010 Dec 29;5(12):e15898. Epub 2010 Dec 29.

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015898PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012110PMC
December 2010

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project.

Authors:
Mark B Gerstein Zhi John Lu Eric L Van Nostrand Chao Cheng Bradley I Arshinoff Tao Liu Kevin Y Yip Rebecca Robilotto Andreas Rechtsteiner Kohta Ikegami Pedro Alves Aurelien Chateigner Marc Perry Mitzi Morris Raymond K Auerbach Xin Feng Jing Leng Anne Vielle Wei Niu Kahn Rhrissorrakrai Ashish Agarwal Roger P Alexander Galt Barber Cathleen M Brdlik Jennifer Brennan Jeremy Jean Brouillet Adrian Carr Ming-Sin Cheung Hiram Clawson Sergio Contrino Luke O Dannenberg Abby F Dernburg Arshad Desai Lindsay Dick Andréa C Dosé Jiang Du Thea Egelhofer Sevinc Ercan Ghia Euskirchen Brent Ewing Elise A Feingold Reto Gassmann Peter J Good Phil Green Francois Gullier Michelle Gutwein Mark S Guyer Lukas Habegger Ting Han Jorja G Henikoff Stefan R Henz Angie Hinrichs Heather Holster Tony Hyman A Leo Iniguez Judith Janette Morten Jensen Masaomi Kato W James Kent Ellen Kephart Vishal Khivansara Ekta Khurana John K Kim Paulina Kolasinska-Zwierz Eric C Lai Isabel Latorre Amber Leahey Suzanna Lewis Paul Lloyd Lucas Lochovsky Rebecca F Lowdon Yaniv Lubling Rachel Lyne Michael MacCoss Sebastian D Mackowiak Marco Mangone Sheldon McKay Desirea Mecenas Gennifer Merrihew David M Miller Andrew Muroyama John I Murray Siew-Loon Ooi Hoang Pham Taryn Phippen Elicia A Preston Nikolaus Rajewsky Gunnar Rätsch Heidi Rosenbaum Joel Rozowsky Kim Rutherford Peter Ruzanov Mihail Sarov Rajkumar Sasidharan Andrea Sboner Paul Scheid Eran Segal Hyunjin Shin Chong Shou Frank J Slack Cindie Slightam Richard Smith William C Spencer E O Stinson Scott Taing Teruaki Takasaki Dionne Vafeados Ksenia Voronina Guilin Wang Nicole L Washington Christina M Whittle Beijing Wu Koon-Kiu Yan Georg Zeller Zheng Zha Mei Zhong Xingliang Zhou Julie Ahringer Susan Strome Kristin C Gunsalus Gos Micklem X Shirley Liu Valerie Reinke Stuart K Kim LaDeana W Hillier Steven Henikoff Fabio Piano Michael Snyder Lincoln Stein Jason D Lieb Robert H Waterston

Science 2010 Dec 22;330(6012):1775-87. Epub 2010 Dec 22.

Program in Computational Biology and Bioinformatics, Yale University, Bass 432, 266 Whitney Avenue, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1196914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142569PMC
December 2010

Genome-wide analysis of germ cell proliferation in C.elegans identifies VRK-1 as a key regulator of CEP-1/p53.

Dev Biol 2010 Aug 23;344(2):1011-25. Epub 2010 Jun 23.

Yale University School of Medicine, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2010.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375680PMC
August 2010

Learning "graph-mer" motifs that predict gene expression trajectories in development.

PLoS Comput Biol 2010 Apr 29;6(4):e1000761. Epub 2010 Apr 29.

Department of Physics, Columbia University, New York, New York, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1000761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861633PMC
April 2010

C. elegans sym-1 is a downstream target of the hunchback-like-1 developmental timing transcription factor.

Cell Cycle 2009 Dec 9;8(24):4147-54. Epub 2009 Dec 9.

Initiative for the Promotion of Young Scientists' Independent Research, Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895549PMC
http://dx.doi.org/10.4161/cc.8.24.10292DOI Listing
December 2009

Protein kinase VRK-1 regulates cell invasion and EGL-17/FGF signaling in Caenorhabditis elegans.

Dev Biol 2009 Nov 11;335(1):12-21. Epub 2009 Aug 11.

Centro Andaluz de Biología del Desarrollo (CABD), Consejo Superior de Investigaciones Científicas, Universidad Pablo de Olavide, Seville 41013, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2009.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378332PMC
November 2009

DPL-1 (DP) acts in the germ line to coordinate ovulation and fertilization in C. elegans.

Mech Dev 2009 May-Jun;126(5-6):406-16. Epub 2009 Feb 6.

Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mod.2009.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680456PMC
July 2009

Germline expression influences operon organization in the Caenorhabditis elegans genome.

Genetics 2009 Apr 9;181(4):1219-28. Epub 2009 Feb 9.

Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.108.099283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666493PMC
April 2009

Massively parallel sequencing of the polyadenylated transcriptome of C. elegans.

Genome Res 2009 Apr 30;19(4):657-66. Epub 2009 Jan 30.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195-5065, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.088112.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665784PMC
April 2009

Gene regulation: a tale of germline mRNA tails.

Authors:
Valerie Reinke

Curr Biol 2008 Oct;18(19):R915-6

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2008.08.001DOI Listing
October 2008

C. elegans nucleostemin is required for larval growth and germline stem cell division.

PLoS Genet 2008 Aug 22;4(8):e1000181. Epub 2008 Aug 22.

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1000181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515194PMC
August 2008

Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during Caenorhabditis elegans oogenesis.

J Cell Biol 2008 Aug;182(3):543-57

Joslin Diabetes Center, Harvard Stem Cell Institute, and 2Department of Pathology, Harvard Medical School, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200801183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500139PMC
August 2008

A C. elegans Piwi, PRG-1, regulates 21U-RNAs during spermatogenesis.

Curr Biol 2008 Jun 22;18(12):861-7. Epub 2008 May 22.

Department of Genetics, School of Medicine, Yale University, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S096098220800606
Publisher Site
http://dx.doi.org/10.1016/j.cub.2008.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494713PMC
June 2008

The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells.

Dev Biol 2008 Apr 8;316(1):50-61. Epub 2008 Jan 8.

Department of Genetics, School of Medicine, Yale University, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2007.12.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359152PMC
April 2008

DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.

Development 2008 Mar 30;135(5):983-93. Epub 2008 Jan 30.

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

View Article

Download full-text PDF

Source
http://dev.biologists.org/cgi/doi/10.1242/dev.015552
Publisher Site
http://dx.doi.org/10.1242/dev.015552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435365PMC
March 2008

MEG-1 and MEG-2 are embryo-specific P-granule components required for germline development in Caenorhabditis elegans.

Genetics 2008 Jan;178(1):295-306

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

View Article

Download full-text PDF

Source
http://www.genetics.org/lookup/doi/10.1534/genetics.107.0802
Publisher Site
http://dx.doi.org/10.1534/genetics.107.080218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206079PMC
January 2008

Germline genomics.

Authors:
Valerie Reinke

WormBook 2006 Jan 20:1-10. Epub 2006 Jan 20.

Department of Genetics, Yale University, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1895/wormbook.1.74.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780938PMC
January 2006

Think globally, act locally.

Authors:
Valerie Reinke

Nat Genet 2007 Mar;39(3):287-9

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng0307-287DOI Listing
March 2007

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.

PLoS Genet 2006 Nov 11;2(11):e183. Epub 2006 Sep 11.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.0020183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635533PMC
November 2006

Expression profiling of MAP kinase-mediated meiotic progression in Caenorhabditis elegans.

PLoS Genet 2006 Nov;2(11):e174

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pgen.0020174
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.0020174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635537PMC
November 2006

Promotion of oogenesis and embryogenesis in the C. elegans gonad by EFL-1/DPL-1 (E2F) does not require LIN-35 (pRB).

Development 2006 Aug 19;133(16):3147-57. Epub 2006 Jul 19.

Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.02490DOI Listing
August 2006

Genome-wide analysis of sex-enriched gene expression during C. elegans larval development.

Dev Biol 2005 Aug;284(2):500-8

Department of Genetics, Cell Biology, and Development, and Developmental Biology Center, University of Minnesota, Minneapolis, MN 55455, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2005.05.017DOI Listing
August 2005

Regulation of tissue-specific and extracellular matrix-related genes by a class I histone deacetylase.

Mol Cell 2005 May;18(4):483-90

Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2005.04.006DOI Listing
May 2005

Sex and the genome.

Authors:
Valerie Reinke

Nat Genet 2004 Jun;36(6):548-9

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ng0604-548
Publisher Site
http://dx.doi.org/10.1038/ng0604-548DOI Listing
June 2004

Genome-wide germline-enriched and sex-biased expression profiles in Caenorhabditis elegans.

Development 2004 Jan 10;131(2):311-23. Epub 2003 Dec 10.

Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.

View Article

Download full-text PDF

Source
http://dev.biologists.org/cgi/doi/10.1242/dev.00914
Publisher Site
http://dx.doi.org/10.1242/dev.00914DOI Listing
January 2004

Coordinate activation of maternal protein degradation during the egg-to-embryo transition in C. elegans.

Dev Cell 2003 Sep;5(3):451-62

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1534-5807(03)00231-4DOI Listing
September 2003

Functional exploration of the C. elegans genome using DNA microarrays.

Authors:
Valerie Reinke

Nat Genet 2002 Dec;32 Suppl:541-6

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1039DOI Listing
December 2002

Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans.

Curr Biol 2002 Nov;12(22):1959-64

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0960-9822(02)01301-5DOI Listing
November 2002

Developmental genomic approaches in model organisms.

Annu Rev Genomics Hum Genet 2002 15;3:153-78. Epub 2002 Apr 15.

Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev.genom.3.031302.100922DOI Listing
December 2002

X-chromosome silencing in the germline of C. elegans.

Development 2002 Jan;129(2):479-92

Biology Department, Emory University, Atlanta, GA 30322, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066729PMC
January 2002