Valerie Gailus-Durner

Valerie Gailus-Durner

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Valerie Gailus-Durner

Valerie Gailus-Durner

Publications by authors named "Valerie Gailus-Durner"

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Costs of Implementing Quality in Research Practice.

Handb Exp Pharmacol 2019 Sep 21. Epub 2019 Sep 21.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1007/164_2019_294DOI Listing
September 2019

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.

Mol Neurobiol 2019 Jun 6;56(6):4215-4230. Epub 2018 Oct 6.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, 85764, Neuherberg, Germany.

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http://link.springer.com/10.1007/s12035-018-1365-5
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http://dx.doi.org/10.1007/s12035-018-1365-5DOI Listing
June 2019

Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.

Exp Eye Res 2019 Apr 13;188:107632. Epub 2019 Apr 13.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, D-85764 Neuherberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183070
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http://dx.doi.org/10.1016/j.exer.2019.03.024DOI Listing
April 2019

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res 2018 10 29;352:187-196. Epub 2017 Sep 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.09.048DOI Listing
October 2018

Analysis of locomotor behavior in the German Mouse Clinic.

J Neurosci Methods 2018 04 5;300:77-91. Epub 2017 May 5.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany; Institute of Developmental Genetics, Helmholtz Zentrum München, Ingolstaedter Landstr.1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.jneumeth.2017.05.005DOI Listing
April 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4 T cells in both mice and humans.

Dev Comp Immunol 2017 12 22;77:69-76. Epub 2017 Jul 22.

National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" - INGM, Via F. Sforza 35, 20122 Milan, Italy; Department of Biosciences, University of Milan, Via Celoria 26, 20133 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dci.2017.07.022DOI Listing
December 2017

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Nature 2017 11 8;551(7680):398. Epub 2017 Nov 8.

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http://dx.doi.org/10.1038/nature24643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849394PMC
November 2017

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.

Cell Metab 2017 Oct 21;26(4):620-632.e6. Epub 2017 Sep 21.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Division of Metabolic Diseases, Department of Medicine, Technische Universität München, 80333 Munich, Germany; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstraße, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.08.023DOI Listing
October 2017

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia.

Glycoconj J 2017 06 6;34(3):393-404. Epub 2016 Sep 6.

Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Klinikum der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s10719-016-9722-yDOI Listing
June 2017

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.

Nucleic Acids Res 2017 04;45(6):3031-3045

Protein Section, Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/nar/gkw1222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389484PMC
April 2017

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).

J Am Assoc Lab Anim Sci 2016 ;55(4):375-86

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Germany; German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany; Experimental Genetics, Center of Life and Food Sciences, Weihenstephan, Technische Universitaet Muenchen, Freising-Weihenstephan, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943607PMC
February 2017

High-throughput discovery of novel developmental phenotypes.

Nature 2016 09 14;537(7621):508-514. Epub 2016 Sep 14.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/nature19356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295821PMC
September 2016

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines.

PLoS One 2015 11;10(8):e0134503. Epub 2015 Aug 11.

Helmholtz Zentrum München GmbH, German Mouse Clinic, Institute of Experimental Genetics, D-85764 Neuherberg, Germany; Technische Universität München, Chair of Experimental Genetics, D-85354 Freising, Germany; German Center for Diabetes Research (DZD), D-85764 Neuherberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134503PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532500PMC
May 2016

Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse.

J Proteomics 2016 Feb 9;133:66-75. Epub 2015 Dec 9.

Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland; Turku Center for Disease Modeling, University of Turku, Turku, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2015.12.009DOI Listing
February 2016

Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice.

J Breath Res 2016 Feb 10;10(1):016009. Epub 2016 Feb 10.

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Munich, Germany. German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Munich, Germany. German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1088/1752-7155/10/1/016009DOI Listing
February 2016

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.

Arterioscler Thromb Vasc Biol 2016 Jan 12;36(1):122-33. Epub 2015 Nov 12.

From the Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark (A.S., B.P., L.E.H., K.K., G.B.K., H.W.-J., J.B.M., K.K.-M., L.K.D., P.B.L.H., J.S., U.H, G.L.S.); Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark (E.-M.F.); Department of Pathology, Odense University Hospital, Odense, Denmark (O.N.); Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany (C.W., J.H., M.O.); Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany (C.W., J.H., M.O.); REBIRTH Cluster of Excellence, Hannover, Germany (C.W., J.H., M.O.); German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany (B.R., A.S., V.G.-D., H.F., M.H.d.A.); Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-University München, Munich, Germany (B.R, E.W.); Division of Cardiology, Department of Medicine III, University of Heidelberg, Heidelberg, Germany (A.S., R.B.); Chair of Experimental Genetics, Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising-Weihenstephan, Munich, Germany (M.H.d.A.); Cardiovascular Research Unit, Viborg Hospital, Viborg, Denmark (J.S.L.); and Department of Cardiothoracic and Vascular Surgery, Center of Individualized Medicine in Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark (J.S.L.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306672DOI Listing
January 2016

Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing.

Hum Mol Genet 2015 Dec 12;24(25):7286-94. Epub 2015 Oct 12.

Department of Laboratory Medicine, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany

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http://dx.doi.org/10.1093/hmg/ddv427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664167PMC
December 2015

Tests for Anxiety-Related Behavior in Mice.

Curr Protoc Mouse Biol 2015 Dec 2;5(4):291-309. Epub 2015 Dec 2.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Munich, Germany.

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http://dx.doi.org/10.1002/9780470942390.mo150010DOI Listing
December 2015

Assessing Cognition in Mice.

Curr Protoc Mouse Biol 2015 Dec 2;5(4):331-358. Epub 2015 Dec 2.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.

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http://dx.doi.org/10.1002/9780470942390.mo150068DOI Listing
December 2015

MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.

PLoS One 2014 15;9(12):e114918. Epub 2014 Dec 15.

Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University, Munich, Germany; German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environment and Health, Neuherberg, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; German Center for Vertigo and Balance Disorders, Munich, Germany; German Network for Mitochondrial Disorders (mitoNET), Munich, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:2147508:2/comp
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http://dx.plos.org/10.1371/journal.pone.0114918
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266617PMC
November 2015

Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors.

Front Behav Neurosci 2015 12;9:302. Epub 2015 Nov 12.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health Neuherberg, Germany ; German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health Neuherberg, Germany.

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http://dx.doi.org/10.3389/fnbeh.2015.00302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642364PMC
November 2015

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Erratum to: High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice.

Int J Cardiovasc Imaging 2015 Aug;31(6):1137

Institute of Experimental Genetics and the German Mouse Clinic, Helmholtz-Zentrum München, German Center for Environmental Health, Building 34/32; R207, Neuherberg, Germany,

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http://link.springer.com/10.1007/s10554-015-0667-1
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http://dx.doi.org/10.1007/s10554-015-0667-1DOI Listing
August 2015

MiR-34a deficiency accelerates medulloblastoma formation in vivo.

Int J Cancer 2015 May 25;136(10):2293-303. Epub 2014 Nov 25.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Hufelandstr. 55 45147, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29294DOI Listing
May 2015

High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice.

Int J Cardiovasc Imaging 2015 Apr 28;31(4):669-79. Epub 2015 Jan 28.

Institute of Experimental Genetics and the German Mouse Clinic, Helmholtz-Zentrum München, German Center for Environmental Health, Building 34/32; R207, Neuherberg, Germany,

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http://dx.doi.org/10.1007/s10554-015-0596-zDOI Listing
April 2015

Glucose tolerance tests for systematic screening of glucose homeostasis in mice.

Curr Protoc Mouse Biol 2015 Mar 2;5(1):65-84. Epub 2015 Mar 2.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1002/9780470942390.mo140111DOI Listing
March 2015

Peroxidasin is essential for eye development in the mouse.

Hum Mol Genet 2014 Nov 3;23(21):5597-614. Epub 2014 Jun 3.

Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Developmental Genetics, Neuherberg, Germany, German Mouse Clinic, Neuherberg, Germany,

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http://hmg.oxfordjournals.org/content/early/2014/06/16/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu274
Publisher Site
http://dx.doi.org/10.1093/hmg/ddu274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189897PMC
November 2014

High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains.

J Comp Physiol B 2014 Aug 1;184(6):763-75. Epub 2014 May 1.

Institute of Experimental Genetics and the German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany,

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http://link.springer.com/10.1007/s00360-014-0830-3
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http://dx.doi.org/10.1007/s00360-014-0830-3DOI Listing
August 2014

A robust and reliable non-invasive test for stress responsivity in mice.

Front Behav Neurosci 2014 15;8:125. Epub 2014 Apr 15.

Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics Neuherberg, Germany ; German Mouse Clinic, Helmholtz Zentrum München Neuherberg, Germany.

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http://journal.frontiersin.org/article/10.3389/fnbeh.2014.00
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http://dx.doi.org/10.3389/fnbeh.2014.00125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995076PMC
April 2014

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis.

Mol Metab 2013 3;2(4):435-46. Epub 2013 Aug 3.

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany ; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1016/j.molmet.2013.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855089PMC
December 2013

Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters.

Mamm Genome 2013 Oct 6;24(9-10):376-88. Epub 2013 Oct 6.

Helmholtz Zentrum München, German Mouse Clinic, Institute of Experimental Genetics, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, 85764, Neuherberg, Germany,

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http://dx.doi.org/10.1007/s00335-013-9477-8DOI Listing
October 2013

Novel small-eye allele in paired box gene 6 (Pax6) is caused by a point mutation in intron 7 and creates a new exon.

Mol Vis 2013 12;19:877-84. Epub 2013 Apr 12.

Helmholtz Center Munich, German Research Center for Environmental Health, German Mouse Clinic, Institute of Developmental Genetics, Neuherberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626302PMC
September 2013

Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum.

Curr Protoc Mouse Biol 2013 Jun 1;3(2):69-100. Epub 2013 Jun 1.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Research Center for Environmental Health, GmbH, Neuherberg, Germany.

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http://dx.doi.org/10.1002/9780470942390.mo130043DOI Listing
June 2013

Blood Collection from Mice and Hematological Analyses on Mouse Blood.

Curr Protoc Mouse Biol 2013 Jun 1;3(2):101-19. Epub 2013 Jun 1.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Research Center for Environmental Health, GmbH, Neuherberg, Germany.

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http://dx.doi.org/10.1002/9780470942390.mo130054DOI Listing
June 2013