Publications by authors named "Valerie Dupé"

28Publications

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit.

Authors:
Glenda Evangelina Comai Markéta Tesařová Valérie Dupé Muriel Rhinn Pedro Vallecillo-García Fabio da Silva Betty Feret Katherine Exelby Pascal Dollé Leif Carlsson Brian Pryce François Spitz Sigmar Stricker Tomáš Zikmund Jozef Kaiser James Briscoe Andreas Schedl Norbert B Ghyselinck Ronen Schweitzer Shahragim Tajbakhsh

PLoS Biol 2020 11 17;18(11):e3000902. Epub 2020 Nov 17.

Stem Cells & Development Unit, Institut Pasteur, Paris, France.

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November 2020

Synonymous variants in holoprosencephaly alter codon usage and impact the Sonic Hedgehog protein.

Authors:
Artem Kim Jérôme Le Douce Farah Diab Monika Ferovova Christèle Dubourg Sylvie Odent Valérie Dupé Véronique David Luis Diambra Erwan Watrin Marie de Tayrac

Brain 2020 07;143(7):2027-2038

Univ Rennes, CNRS, IGDR (Institut de génétique et développement de Rennes)-UMR 6290, F-35000 Rennes, France.

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July 2020

MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome.

Authors:
Ilaria Parenti Farah Diab Sara Ruiz Gil Eskeatnaf Mulugeta Valentina Casa Riccardo Berutti Rutger W W Brouwer Valerie Dupé Juliane Eckhold Elisabeth Graf Beatriz Puisac Feliciano Ramos Thomas Schwarzmayr Macarena Moronta Gines Thomas van Staveren Wilfred F J van IJcken Tim M Strom Juan Pié Erwan Watrin Frank J Kaiser Kerstin S Wendt

Cell Rep 2020 05;31(7):107647

Department of Cell Biology, Erasmus MC, Rotterdam, the Netherlands. Electronic address:

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May 2020

Disrupted Hypothalamo-Pituitary Axis in Association With Reduced SHH Underlies the Pathogenesis of NOTCH-Deficiency.

Authors:
Houda Hamdi-Rozé Michelle Ware Hélène Guyodo Aurélie Rizzo Leslie Ratié Maïlys Rupin Wilfrid Carré Artem Kim Sylvie Odent Christèle Dubourg Véronique David Marie de Tayrac Valérie Dupé

J Clin Endocrinol Metab 2020 Sep;105(9)

Univ Rennes, CNRS, IGDR - Institut de Génétique et Développement de Rennes - UMR6290, Rennes, France.

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September 2020

Targeted panel sequencing establishes the implication of planar cell polarity pathway and involves new candidate genes in neural tube defect disorders.

Authors:
Marie Beaumont Linda Akloul Wilfrid Carré Chloé Quélin Hubert Journel Laurent Pasquier Mélanie Fradin Sylvie Odent Houda Hamdi-Rozé Erwan Watrin Valérie Dupé Christèle Dubourg Véronique David

Hum Genet 2019 Apr 5;138(4):363-374. Epub 2019 Mar 5.

Service de Génétique Moléculaire et Génomique, CHU Pontchaillou, 2 rue Henri le Guilloux, 35033, Rennes, France.

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April 2019

Integrated clinical and omics approach to rare diseases: novel genes and oligogenic inheritance in holoprosencephaly.

Authors:
Artem Kim Clara Savary Christèle Dubourg Wilfrid Carré Charlotte Mouden Houda Hamdi-Rozé Hélène Guyodo Jerome Le Douce Laurent Pasquier Elisabeth Flori Marie Gonzales Claire Bénéteau Odile Boute Tania Attié-Bitach Joelle Roume Louise Goujon Linda Akloul Sylvie Odent Erwan Watrin Valérie Dupé Marie de Tayrac Véronique David

Brain 2019 01;142(1):35-49

Univ Rennes, CNRS, IGDR (Institut de génétique et développement de Rennes) - UMR 6290, F-35000 Rennes, France.

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January 2019

A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis.

Authors:
Myriam Vezain Matthieu Lecuyer Marina Rubio Valérie Dupé Leslie Ratié Véronique David Laurent Pasquier Sylvie Odent Sophie Coutant Isabelle Tournier Laetitia Trestard Homa Adle-Biassette Denis Vivien Thierry Frébourg Bruno J Gonzalez Annie Laquerrière Pascale Saugier-Veber

Acta Neuropathol Commun 2018 10 19;6(1):109. Epub 2018 Oct 19.

Normandie Univ, UNIROUEN, Inserm U1245, Normandy Centre for Genomic and Personalized Medicine, F 76000, Rouen, France.

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October 2018

Recent advances in understanding inheritance of holoprosencephaly.

Authors:
Christèle Dubourg Artem Kim Erwan Watrin Marie de Tayrac Sylvie Odent Véronique David Valérie Dupé

Am J Med Genet C Semin Med Genet 2018 06 22;178(2):258-269. Epub 2018 May 22.

Univ Rennes, CNRS, IGDR (Institut de génétique et développement de Rennes) - UMR 6290, F - 35000, Rennes, France.

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June 2018

[From cyclops to reality: a fresh look at the genetics of holoprosencephaly].

Authors:
Valérie Dupé Christèle Dubourg Marie de Tayrac Véronique David

Med Sci (Paris) 2017 Nov 4;33(11):924-926. Epub 2017 Dec 4.

UMR 6290 CNRS, institut de génétique et développement de Rennes, université de Rennes1, France - Service de génétique moléculaire et génomique, CHU Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes, France.

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November 2017

Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain.

Authors:
Michelle Ware Houda Hamdi-Rozé Julien Le Friec Véronique David Valérie Dupé

Neural Dev 2016 12 7;11(1):22. Epub 2016 Dec 7.

Institut de Génétique et Développement de Rennes, Faculté de Médecine, CNRS UMR6290, Université de Rennes 1, IFR140 GFAS, 2 Avenue du Pr. Léon Bernard, 35043, Rennes Cedex, France.

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December 2016

Mutational Spectrum in Holoprosencephaly Shows That FGF is a New Major Signaling Pathway.

Authors:
Christèle Dubourg Wilfrid Carré Houda Hamdi-Rozé Charlotte Mouden Joëlle Roume Benmansour Abdelmajid Daniel Amram Clarisse Baumann Nicolas Chassaing Christine Coubes Laurence Faivre-Olivier Emmanuelle Ginglinger Marie Gonzales Annie Levy-Mozziconacci Sally-Ann Lynch Sophie Naudion Laurent Pasquier Amélie Poidvin Fabienne Prieur Pierre Sarda Annick Toutain Valérie Dupé Linda Akloul Sylvie Odent Marie de Tayrac Véronique David

Hum Mutat 2016 12 23;37(12):1329-1339. Epub 2016 Aug 23.

Service de Génétique Moléculaire et Génomique, CHU, Rennes, France.

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December 2016

Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain.

Authors:
Michelle Ware Valérie Dupé Frank R Schubert

Dev Dyn 2015 Oct 13;244(10):1202-14. Epub 2015 Aug 13.

Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth, United Kingdom.

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October 2015

Homozygous STIL mutation causes holoprosencephaly and microcephaly in two siblings.

Authors:
Charlotte Mouden Marie de Tayrac Christèle Dubourg Sophie Rose Wilfrid Carré Houda Hamdi-Rozé Marie-Claude Babron Linda Akloul Bénédicte Héron-Longe Sylvie Odent Valérie Dupé Régis Giet Véronique David

PLoS One 2015 6;10(2):e0117418. Epub 2015 Feb 6.

Institut de Génétique et Développement de Rennes, Equipe Génétique des Pathologies Liées au Développement, Faculté de Médecine, Université de Rennes 1, 35043 Rennes, France; Laboratoire de Génétique Moléculaire et Génomique, CHU Pontchaillou, 35033 Rennes, France.

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February 2016

Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system.

Authors:
Leslie Ratié Michelle Ware Hélène Jagline Véronique David Valérie Dupé

Front Neuroanat 2014 18;8:158. Epub 2014 Dec 18.

CNRS UMR6290, Faculté de Médecine, Institut de Génétique et Développement de Rennes, Université de Rennes 1 Rennes, France.

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January 2015

Notch signaling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamus.

Authors:
Michelle Ware Houda Hamdi-Rozé Valérie Dupé

Front Neuroanat 2014 2;8:140. Epub 2014 Dec 2.

Institut de Génétique et Développement de Rennes, Faculté de Médecine, CNRS UMR6290, Université de Rennes 1 Rennes, France.

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December 2014

Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development.

Authors:
Leslie Ratié Michelle Ware Frédérique Barloy-Hubler Hélène Romé Isabelle Gicquel Christèle Dubourg Véronique David Valérie Dupé

Neural Dev 2013 Dec 23;8:25. Epub 2013 Dec 23.

Institut de Génétique et Développement de Rennes, CNRS UMR6290, Université de Rennes 1, IFR140 GFAS, Faculté de Médecine, Rennes, France.

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December 2013

NODAL and SHH dose-dependent double inhibition promotes an HPE-like phenotype in chick embryos.

Authors:
Sandra Mercier Véronique David Leslie Ratié Isabelle Gicquel Sylvie Odent Valérie Dupé

Dis Model Mech 2013 Mar 20;6(2):537-43. Epub 2012 Dec 20.

Institut de Génétique et Développement, CNRS UMR6290, Université de Rennes 1, IFR140 GFAS, Faculté de Médecine, 35043 Rennes, France.

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March 2013

New findings for phenotype-genotype correlations in a large European series of holoprosencephaly cases.

Authors:
Sandra Mercier Christèle Dubourg Nicolas Garcelon Boris Campillo-Gimenez Isabelle Gicquel Marion Belleguic Leslie Ratié Laurent Pasquier Philippe Loget Claude Bendavid Sylvie Jaillard Lucie Rochard Chloé Quélin Valérie Dupé Véronique David Sylvie Odent

J Med Genet 2011 Nov 22;48(11):752-60. Epub 2011 Sep 22.

Service de Génétique Clinique, CLAD Ouest, CHU Rennes, Rennes, France.

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November 2011

NOTCH, a new signaling pathway implicated in holoprosencephaly.

Authors:
Valérie Dupé Lucie Rochard Sandra Mercier Yann Le Pétillon Isabelle Gicquel Claude Bendavid Georges Bourrouillou Usha Kini Christel Thauvin-Robinet Timothy P Bohan Sylvie Odent Christèle Dubourg Véronique David

Hum Mol Genet 2011 Mar 31;20(6):1122-31. Epub 2010 Dec 31.

Institut de Génétique et Développement, CNRS UMR6061, Université de Rennes 1, IFR140 GFAS, Faculté de Médecine, Rennes, France.

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March 2011

Conditional ablation of integrin alpha-6 in mouse epidermis leads to skin fragility and inflammation.

Authors:
Cristina Niculescu Gitali Ganguli-Indra Véronique Pfister Valérie Dupé Nadia Messaddeq Adèle De Arcangelis Elisabeth Georges-Labouesse

Eur J Cell Biol 2011 Feb-Mar;90(2-3):270-7. Epub 2010 Oct 20.

Institut de génétique et de biologie moléculaire et cellulaire, Department of Cell Biology and Development, CNRS UdS UMR7104, Inserm U964, Illkirch, France.

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July 2011

Holoprosencephaly: An update on cytogenetic abnormalities.

Authors:
Claude Bendavid Valérie Dupé Lucie Rochard Isabelle Gicquel Christèle Dubourg Véronique David

Am J Med Genet C Semin Med Genet 2010 Feb;154C(1):86-92

Institut National de la Santé et de la Recherche Médicale, Rennes, France.

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February 2010

Retinoic acid receptors exhibit cell-autonomous functions in cranial neural crest cells.

Authors:
Valérie Dupé Isabelle Pellerin

Dev Dyn 2009 Oct;238(10):2701-11

Faculté de Médecine, Institut de Génétique et Développement, Université de Rennes 1, Rennes Cedex, France.

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October 2009

Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis.

Authors:
Nicolas Matt Norbert B Ghyselinck Isabelle Pellerin Valérie Dupé

Dev Biol 2008 Aug 11;320(1):140-8. Epub 2008 May 11.

UPR9022 du CNRS, IBMC, 15 rues Descartes, 67084 Strasbourg, France.

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August 2008

Identification of a new type of PBX1 partner that contains zinc finger motifs and inhibits the binding of HOXA9-PBX1 to DNA.

Authors:
Audrey Laurent Réjane Bihan Stéphane Deschamps Daniel Guerrier Valérie Dupé Francis Omilli Agnès Burel Isabelle Pellerin

Mech Dev 2007 May 8;124(5):364-76. Epub 2007 Feb 8.

UMR CNRS 6061, Génétique et Développement, IFR 140, Faculté de Médecine, Université de Rennes 1, Campus Villejean, 2 avenue du Professeur Léon Bernard, CS34317, F-35043 Rennes Cedex, France.

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May 2007

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells.

Authors:
Nicolas Matt Valérie Dupé Jean-Marie Garnier Christine Dennefeld Pierre Chambon Manuel Mark Norbert B Ghyselinck

Development 2005 Nov 5;132(21):4789-800. Epub 2005 Oct 5.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC Collège de France, BP10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

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November 2005

Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.

Authors:
Arup Kumar Indra Valérie Dupé Jean-Marc Bornert Nadia Messaddeq Moshe Yaniv Manuel Mark Pierre Chambon Daniel Metzger

Development 2005 Oct;132(20):4533-44

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Strasbourg, France.

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October 2005

Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.

Authors:
Nicolas Matt Carsten K Schmidt Valérie Dupé Christine Dennefeld Heinz Nau Pierre Chambon Manuel Mark Norbert B Ghyselinck

Dev Dyn 2005 May;233(1):167-76

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut Clinique de la Souris (ICS), CNRS/INSERM/ULP, Collège de France, BP10142, 67404 Illkirch Cedex, CU de Strasbourg, France.

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May 2005

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.

Authors:
Valérie Dupé Nicolas Matt Jean-Marie Garnier Pierre Chambon Manuel Mark Norbert B Ghyselinck

Proc Natl Acad Sci U S A 2003 Nov 17;100(24):14036-41. Epub 2003 Nov 17.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, Université Louis Pasteur, Collège de France, BP10142, 67404 Illkirch Cedex, Communauté Urbaine de Strasbourg, France.

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November 2003