Publications by authors named "Valerie Devauchelle-Pensec"

100Publications

Tocilizumab controls bone turnover in early polymyalgia rheumatica.

Joint Bone Spine 2020 Dec 7:105117. Epub 2020 Dec 7.

Laboratory of immunology and immunotherapy, UMR1227, CHRU Morvan, Brest, France.

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December 2020

Systemic phenotype related to primary Sjögren's syndrome in 279 patients carrying isolated anti-La/SSB antibodies.

Clin Exp Rheumatol 2020 Jul-Aug;38 Suppl 126(4):85-94. Epub 2020 Oct 22.

Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic, Barcelona, and Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA-Sanitas, Barcelona, Spain.

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October 2020

The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle.

Autoimmun Rev 2020 Nov 15;19(11):102670. Epub 2020 Sep 15.

Univ Brest, Inserm, CHU de Brest, LBAI, UMR1227, Brest, France; Service de Rhumatologie, Centre de Référence Maladies Autoimmunes Rares CERAINO, CHU Cavale Blanche, Brest, France.

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November 2020

Aortic involvement in giant cell arteritis.

Joint Bone Spine 2020 Jul 7:105045. Epub 2020 Jul 7.

UMR 1227 « Lymphocytes B et Autoimmunité », Inserm, Labex IGO, University of Brest, Brest, France; Rheumatology department, CERAINO « Centre de référence des maladies auto-immunes rares », CHRU Cavale Blanche, Brest, France. Electronic address:

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July 2020

Is Tocilizumab as efficient as steroids early in polymyalgia rheumatica?

Semin Arthritis Rheum 2020 08 16;50(4):582. Epub 2020 May 16.

Univ Brest, Inserm, CHU de Brest, LBAI, UMR1227, Brest, France; Service de rhumatologie, Centre de Référence Maladies Autoimmunes Rares CERAINO, CHU Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest, France. Electronic address:

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August 2020

Epigenetics in Primary Sjögren's Syndrome.

Adv Exp Med Biol 2020 ;1253:285-308

INSERM U1227, «Lymphocyte B et autoimmunité», Labex Igo "Immunotherapy Graft, Oncology", Réseau épigénétique du cancéropole Grand Ouest, Université de Brest, Brest, France.

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July 2020

Seasonal effect on fatigue, pain and dryness in primary Sjögren's syndrome.

Arthritis Res Ther 2020 02 24;22(1):39. Epub 2020 Feb 24.

Department of Rheumatology, Referral Center for Rare Autoimmune and Systemic Diseases, Strasbourg University Hospital, Strasbourg, France.

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February 2020

Should we use ultrasonography in the clinic to detect pSS?

Nat Rev Rheumatol 2019 11;15(11):642-643

Department of Rheumatology, Brest University Hospital, Brest, France.

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November 2019

Plea for standardization of disease activity scores.

Rheumatology (Oxford) 2019 08;58(8):1500-1501

Rheumatology Department, Centre National de Référence des Maladies Auto-Immunes Rares du Nord Ouest (CeRAINO), Brest, CHU Brest.

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August 2019

Salivary gland ultrasonography in primary Sjögren's syndrome: opportunities and challenges.

Rheumatology (Oxford) 2019 Mar 19. Epub 2019 Mar 19.

Rheumatology Clinic, Department of Medical and Biological Sciences, Santa Maria della Misericordia University Hospital, Udine, Italy.

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March 2019

Localized Myofascial Inflammation Revealed by Magnetic Resonance Imaging in Recent-onset Polymyalgia Rheumatica and Effect of Tocilizumab Therapy.

J Rheumatol 2019 12 15;46(12):1619-1626. Epub 2019 Mar 15.

From the Radiology department, Centre Hospitalier Universitaire (CHU) de Brest; Rheumatology department, Centre National de Référence des Maladies Auto-Immunes Rares (CERAINO), CHU Brest; INSERM UMR 1227, Laboratoire d'Immunothérapie et Pathologies lymphocytaires B, Labex Immunotherapy, Graft, Oncology, Université de Brest, Brest, France.

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December 2019

Peripheral-blood b-cell subset disturbances in inflammatory joint diseases induced by Tropheryma whipplei.

PLoS One 2019 27;14(2):e0211536. Epub 2019 Feb 27.

Rheumatology Unit, Centre National de Référence des Maladies Auto-Immunes Rares (CERAINO), Victor Hugo Network, Brest Teaching Hospital, Brest, France.

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December 2019

Assessment of major salivary gland size in primary Sjögren's syndrome: Comparison between clinical examination and ultrasonography.

Joint Bone Spine 2019 Oct 11;86(5):627-632. Epub 2019 Feb 11.

Service de rhumatologie, centre national de référence des maladies auto-immunes rares de l'adulte CERAINO, CHU de Brest, 29200 Brest, France; UMR1227, lymphocytes B et autoimmunité, université de Brest, Inserm, LabEx IGO, 29200 Brest, France.

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October 2019

Time-course of ultrasound abnormalities of major salivary glands in suspected Sjögren's syndrome.

Joint Bone Spine 2018 03 27;85(2):227-232. Epub 2017 Feb 27.

Rheumatology Unit, Hôpital de la Cavale Blanche, Brest 29609, France; INSERM U1227, Université de Brest, LabEx IGO, 29609 Brest, France.

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March 2018

Vascular endothelial growth factor levels and rheumatic diseases of the elderly.

Arthritis Res Ther 2016 12 1;18(1):283. Epub 2016 Dec 1.

Département de rhumatologie, Centre Hospitalier Universitaire Gabriel Montpied, 58, rue Montalembert, 63000, Clermont-Ferrand, France.

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December 2016

Interleukin-6: a promising target for the treatment of polymyalgia rheumatica or giant cell arteritis?

RMD Open 2016 31;2(2):e000305. Epub 2016 Aug 31.

Department of Internal Medicine , Centre de référence maladies auto-immunes et systémiques rares, Hôpital Cochin, AP-HP , Paris , France.

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August 2016

Has the time come for biotherapies in giant cell arteritis and polymyalgia rheumatica?

Joint Bone Spine 2016 Oct 12;83(5):471-2. Epub 2016 Aug 12.

Département de rhumatologie, hôpital de la Cavale-Blanche, 29609 Brest, France; EA2216, INSERM ESPRI, ERI29, université de Brest, LabEx IGO, 29609 Brest, France. Electronic address:

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October 2016

Treatment of primary Sjögren syndrome.

Nat Rev Rheumatol 2016 08 14;12(8):456-71. Epub 2016 Jul 14.

EA2216, INSERM ESPRI ERI29, Laboratoire d'Immunothérapie et Pathologies lymphocytaires B, Université de Brest, Labex 'Immunotherapy, Graft, Oncology', 29609 Brest Cedex, France.

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August 2016

The active immunological profile in patients with primary Sjögren's syndrome is restricted to typically encountered autoantibodies.

Clin Exp Rheumatol 2016 Jul-Aug;34(4):722. Epub 2016 May 9.

Laboratory of Immunology and Immunotherapy, CHU Morvan, Brest; and INSERM ESPRI, ERI29/EA2216, Innovative Medicines Initiative PRECISESADS, European University of Brittany, Brest, France.

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September 2016

Comparison of modified disease-activity scores with original composite scores for prediction of structural damages in rheumatoid arthritis: Data from the ESPOIR cohort.

Joint Bone Spine 2017 Jan 23;84(1):111-112. Epub 2016 Apr 23.

Rheumatology Department, Clermont-Ferrand University Hospital, CHU Gabriel-Montpied, place Henri-Dunant, 63000 Clermont-Ferrand, France.

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January 2017

Efficacy of first-line tocilizumab therapy in early polymyalgia rheumatica: a prospective longitudinal study.

Ann Rheum Dis 2016 Aug 29;75(8):1506-10. Epub 2016 Feb 29.

Rheumatology Department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France EA 2216, ERI 29, Brest University, Brest, France.

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August 2016

Do high numbers of salivary gland-infiltrating B cells predict better or worse outcomes after rituximab in patients with primary Sjögren's syndrome?

Ann Rheum Dis 2016 06 19;75(6):e33. Epub 2016 Feb 19.

EA2216, INSERM ESPRI, ERI29, Laboratoire d'Immunothérapies et Pathologies lymphocytaires B, Université de Brest, and Labex "IGO", Brest, France.

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June 2016

Sicca symptoms are associated with similar fatigue, anxiety, depression, and quality-of-life impairments in patients with and without primary Sjögren's syndrome.

Joint Bone Spine 2016 Dec 13;83(6):681-685. Epub 2016 Jan 13.

Rheumatology Unit and Immunology Department (EA 2216), hôpital de la Cavale-Blanche, université Bretagne-Occidentale, CHU de Brest, BP 814, 29609 Brest cedex, France.

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December 2016

Blood and salivary-gland BAFF-driven B-cell hyperactivity is associated to rituximab inefficacy in primary Sjögren's syndrome.

J Autoimmun 2016 Feb 10;67:102-110. Epub 2015 Dec 10.

EA2216, INSERM ESPRI, ERI29, Laboratoire d'Immunothérapies et Pathologies lymphocytaires B, Université de Brest, and Labex "IGO", Brest, France. Electronic address:

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February 2016

Can ARFI elastometry of the salivary glands contribute to the diagnosis of Sjögren's syndrome?

Joint Bone Spine 2016 May 8;83(3):301-6. Epub 2015 Dec 8.

Service de rhumatologie, CHU de la Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest, France; Unité de médecine vasculaire, CHU de la Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest, France; EA 2216, université Bretagne-Occidentale, BP 824, 29200 Brest, France. Electronic address:

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May 2016

Abatacept efficacy in rheumatoid arthritis is dependent upon baseline blood B-cell levels.

Rheumatology (Oxford) 2016 06 14;55(6):1138-40. Epub 2015 Dec 14.

Service de Rhumatologie, CHRU Brest, EA 2216, INSERM ESPRI, ERI29, Université de Brest, LabEx IGO and

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June 2016

Eosinophilia predicts poor clinical outcomes in recent-onset arthritis: results from the ESPOIR cohort.

RMD Open 2015 15;1(1):e000070. Epub 2015 Jul 15.

Department of Rheumatology , CHU de la Cavale Blanche, Boulevard Tanguy Prigent , Brest , France ; EA 2216, INSERM ESPRI, ERI29 Université Bretagne Occidentale , Brest , France.

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October 2015

Managing monoarthritis in children.

Joint Bone Spine 2016 Jan 4;83(1):25-30. Epub 2015 Aug 4.

Université de Bretagne occidentale, 29200 Brest, France; Département de médecine physique et de réadaptation, CHRU Morvan, 29200 Brest, France.

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January 2016

Lymphopenia in early arthritis: Impact on diagnosis and 3-year outcomes (ESPOIR cohort).

Joint Bone Spine 2015 Dec 14;82(6):417-22. Epub 2015 Jul 14.

Rheumatology unit and immunology department (EA 2216), hôpital de la Cavale-Blanche, CHU de Brest, université Bretagne occidentale, BP 824, 29609 Brest cedex, France. Electronic address:

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December 2015

ANCA-associated vasculitis in patients with primary Sjögren's syndrome: detailed analysis of 7 new cases and systematic literature review.

Autoimmun Rev 2015 Aug 24;14(8):742-50. Epub 2015 Apr 24.

Service de Rhumatologie, CHRU Brest, France; EA2216, INSERM ESPRI, ERI29, Laboratoire d'Immunothérapies et Pathologies lymphocytaires B, Université de Brest, Brest, France. Electronic address:

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August 2015

Genetic contribution of DKK-1 polymorphisms to RA structural severity and DKK-1 level of expression.

Ann Rheum Dis 2015 Jul 24;74(7):1480-1. Epub 2015 Mar 24.

Division of rheumatology, Rosalind Russell / Ephraim P Engleman Rheumatology Research Center, University of California, San Francisco, California, USA.

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July 2015

Reliability of histopathological salivary gland biopsy assessment in Sjögren's syndrome: a multicentre cohort study.

Rheumatology (Oxford) 2015 Jun 27;54(6):1056-64. Epub 2014 Nov 27.

Pathology Department, Brest University Hospital, Brest, France, Pathology Department, Vannes General Hospital, Vannes, Brest Occidental University, Rheumatology Unit, Hôpital de la Cavale Blanche, EA 2216, ESPRI 29, Brest University, Brest, Rheumatology Department, Hôtel Dieu University Hospital, Nantes, Department of Internal Medicine, Nord-de-France University, Claude-Huriez Hospital, Lille, Rheumatology Department, Rouen University Hospital, Rouen and Brest Occidental University, Clinical Investigation Centre, Institut National de la Santé et de la Recherche Médicale, Brest, France Pathology Department, Brest University Hospital, Brest, France, Pathology Department, Vannes General Hospital, Vannes, Brest Occidental University, Rheumatology Unit, Hôpital de la Cavale Blanche, EA 2216, ESPRI 29, Brest University, Brest, Rheumatology Department, Hôtel Dieu University Hospital, Nantes, Department of Internal Medicine, Nord-de-France University, Claude-Huriez Hospital, Lille, Rheumatology Department, Rouen University Hospital, Rouen and Brest Occidental University, Clinical Investigation Centre, Institut National de la Santé et de la Recherche Médicale, Brest, France

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June 2015

Salivary gland ultrasound to diagnose Sjögren's syndrome: a claim to standardize the procedure.

Rheumatology (Oxford) 2015 Jan 6;54(1):199-200. Epub 2014 Oct 6.

Department of Rheumatology, Brest Teaching Hospital and EA2216, INSERM ESPRI, ERI29, Université de Brest, LabEx IGO, Brest, France. Department of Rheumatology, Brest Teaching Hospital and EA2216, INSERM ESPRI, ERI29, Université de Brest, LabEx IGO, Brest, France.

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January 2015

Is there specific neurological disorders of primary Sjögren's syndrome?

Joint Bone Spine 2015 Mar 20;82(2):86-9. Epub 2014 Jun 20.

Service de rhumatologie, hôpital de la Cavale-Blanche, CHU de Brest, 29609 Brest cedex, France. Electronic address:

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March 2015

SPP1 rs9138 variant contributes to the severity of radiological damage in anti-citrullinated protein autoantibody-negative rheumatoid arthritis.

Ann Rheum Dis 2014 Oct 16;73(10):1840-3. Epub 2014 Jun 16.

Department of Rheumatology, DHU FIRE, Assistance Publique Hôpitaux de Paris, Bichat Hospital, Université Paris Diderot, PRES Sorbonne Paris Cité, Paris, France INSERM U699, Bichat Faculty of Medicine, Université Paris Diderot, PRES Sorbonne Paris Cité, Paris, France.

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October 2014

Salivary gland ultrasonography improves the diagnostic performance of the 2012 American College of Rheumatology classification criteria for Sjögren's syndrome.

Rheumatology (Oxford) 2014 Sep 4;53(9):1604-7. Epub 2014 Apr 4.

Department of Rheumatology, EA 2216 Immunology and Pathology, SFR ScinBios, Labex Immunotherapy, Graft, Oncology, Brest University, Department of Odontology and Laboratory of Immunology and Immunotherapy, Brest Teaching Hospital, Brest, France. Department of Rheumatology, EA 2216 Immunology and Pathology, SFR ScinBios, Labex Immunotherapy, Graft, Oncology, Brest University, Department of Odontology and Laboratory of Immunology and Immunotherapy, Brest Teaching Hospital, Brest, France.

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September 2014

Long-term efficacy of infliximab in autoimmune sensorineural hearing loss associated with rheumatoid arthritis.

Rheumatology (Oxford) 2014 Sep 12;53(9):1715-6. Epub 2014 Mar 12.

Service de Rhumatologie, Hôpital de la Cavale Blanche, Brest Cedex, France.

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September 2014

Ultrasound assessment of the entheses in primary Sjögren syndrome.

Ultrasound Med Biol 2013 Dec 12;39(12):2485-7. Epub 2013 Sep 12.

Unit of Rheumatology, Hôpital de la Cavale Blanche, CHU Brest, France and Unit of Immunology, Morvan Hospital, Brest, France.

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December 2013

The future of B cell-targeted therapies in Sjögren's syndrome.

Immunotherapy 2013 Jun;5(6):639-46

Department of Rheumatology, CHRU la Cavale Blanche, Brest, France.

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June 2013

[Osteoarthritis epidemiology and risk factors].

Soins 2012 Sep(768):28-9

CHRU La Cavale blanche, service de rhumatologie, pôle neuro-locomoteur, Brest.

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September 2012