Valeria V Orlova

Valeria V Orlova

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Valeria V Orlova

Valeria V Orlova

Publications by authors named "Valeria V Orlova"

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38Publications

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Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives.

Stem Cell Reports 2019 Jun;12(6):1282-1297

Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565887PMC
June 2019

Scalable microphysiological system to model three-dimensional blood vessels.

APL Bioeng 2019 Jun 21;3(2):026105. Epub 2019 Jun 21.

Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.

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http://dx.doi.org/10.1063/1.5090986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588522PMC
June 2019

Quantifying Ca signaling and contraction in vascular pericytes and smooth muscle cells.

Biochem Biophys Res Commun 2019 May 30;513(1):112-118. Epub 2019 Mar 30.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, 2333 ZC, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.03.143DOI Listing
May 2019

Quantitative Analysis of Intracellular Ca Release and Contraction in hiPSC-Derived Vascular Smooth Muscle Cells.

Stem Cell Reports 2019 Apr 7;12(4):647-656. Epub 2019 Mar 7.

Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449838PMC
April 2019

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology.

Adv Drug Deliv Rev 2019 Feb 23;140:68-77. Epub 2018 Jun 23.

Applied Stem Cell Technologies group, University of Twente, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0169409X183014
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http://dx.doi.org/10.1016/j.addr.2018.06.007DOI Listing
February 2019

Microfluidic Assay for the Assessment of Leukocyte Adhesion to Human Induced Pluripotent Stem Cell-derived Endothelial Cells (hiPSC-ECs).

J Vis Exp 2018 11 26(141). Epub 2018 Nov 26.

Department of Anatomy and Embryology, Leiden University Medical Center;

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http://dx.doi.org/10.3791/58678DOI Listing
November 2018

Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.

Stem Cell Reports 2018 05 12;10(5):1642-1656. Epub 2018 Apr 12.

Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333ZC Leiden, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183013
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http://dx.doi.org/10.1016/j.stemcr.2018.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995303PMC
May 2018

Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives.

Biomacromolecules 2018 04 12;19(4):1091-1099. Epub 2018 Mar 12.

Department of Supramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry , Leiden University , P.O. Box 9502, 2300 RA , Leiden , The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.biomac.7b01614
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http://dx.doi.org/10.1021/acs.biomac.7b01614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894061PMC
April 2018

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

Circ Res 2018 02 27;122(3):e5-e16. Epub 2017 Dec 27.

From the Department of Anatomy and Embryology, Leiden University Medical Center, The Netherlands (L.S., B.J.v.M., L.G.J.T., M.B., R.P.D., M.A.E.D., E.G., C.G., M.R.M.J., M.P.H.M., V.V.O., R.P., C.L.M.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary, and Life Science, University of Glasgow, United Kingdom (Q.L., G.L.S., F.L.B.); Hubrecht Institute - Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands (J.B., S.M.K., C.D.K.); Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham, United Kingdom (C.D., D.M.); Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Germany (T.E., A.H., I.M., U.S.); DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck (T.E., A.H., I.M., U.S.); Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Hamburg, Germany (U.S.); Hart Long Centrum, Leiden University Medical Center, The Netherlands (E.R.H., M.R.M.J.); Department of Applied Stem Cell Technologies, University of Twente, Enschede, The Netherlands (R.P., M.C.R., C.L.M.).; Division of Heart and Lungs, Department of Medical Physiology, University Medical Center Utrecht, The Netherlands (J.B., S.M.K., C.D.K.); and Clyde Biosciences, Ltd, BioCity Scotland, United Kingdom (G.L.S., F.L.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805275PMC
February 2018

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes.

Stem Cell Reports 2017 12 22;9(6):1765-1779. Epub 2017 Nov 22.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, the Netherlands; Department of Applied Stem Cell Technologies, MIRA Institute, University of Twente, Twente, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711173047
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http://dx.doi.org/10.1016/j.stemcr.2017.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785710PMC
December 2017

Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells.

Stem Cell Reports 2017 12 22;9(6):1754-1764. Epub 2017 Nov 22.

Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, the Netherlands; Department of Applied Stem Cell Technologies, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Building Zuidhorst, 7500 AE Enschede, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785703PMC
December 2017

Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue.

Curr Protoc Hum Genet 2017 10 18;95:21.9.1-21.9.22. Epub 2017 Oct 18.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cphg.46DOI Listing
October 2017

BMP-SMAD signaling: From pluripotent stem cells to cardiovascular commitment.

Cytokine Growth Factor Rev 2016 Feb 24;27:55-63. Epub 2015 Nov 24.

Department Biochemistry and Molecular Biology, BioMedical Center, University of Iceland, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.cytogfr.2015.11.007DOI Listing
February 2016

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.

Stem Cell Reports 2015 Dec 26;5(6):963-970. Epub 2015 Nov 26.

Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center, Leiden 2300, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682290PMC
December 2015

Endothelial-specific deficiency of Junctional Adhesion Molecule-C promotes vessel normalisation in proliferative retinopathy.

Thromb Haemost 2015 Nov 27;114(6):1241-9. Epub 2015 Aug 27.

Matina Economopoulou, Department of Ophthalmology, Univ. Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany, Tel.: +49 351 45819291, E-mail:

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http://dx.doi.org/10.1160/TH15-01-0051DOI Listing
November 2015

Assessment of functional competence of endothelial cells from human pluripotent stem cells in zebrafish embryos.

Methods Mol Biol 2014 ;1213:107-19

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden Einthovenweg 20, 2333, ZC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-1453-1_10DOI Listing
May 2015

What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease.

Cell Stem Cell 2015 May;16(5):455-7

Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909150016
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http://dx.doi.org/10.1016/j.stem.2015.04.006DOI Listing
May 2015

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.

Nat Protoc 2014 29;9(6):1514-31. Epub 2014 May 29.

Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.nature.com/articles/nprot.2014.102
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http://dx.doi.org/10.1038/nprot.2014.102DOI Listing
December 2014

Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.

Arterioscler Thromb Vasc Biol 2014 Jan 24;34(1):177-86. Epub 2013 Oct 24.

From the Department of Anatomy and Embryology (V.V.O., C.F., S.P.-R., F.E.v.d.H., S.M., C.L.M.) and Department of Molecular Cell Biology (V.V.O., Y.D., P.t.D.), Cancer Genomics Centre and Centre for Biomedical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.113.302598DOI Listing
January 2014

Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device.

Lab Chip 2013 Sep;13(18):3562-8

BIOS/Lab on a Chip, MESA+ Institute for Nanotechnology, University of Twente, The Netherlands.

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http://xlink.rsc.org/?DOI=c3lc50435b
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http://dx.doi.org/10.1039/c3lc50435bDOI Listing
September 2013

Controlling angiogenesis by two unique TGF-β type I receptor signaling pathways.

Histol Histopathol 2011 09;26(9):1219-30

Department of Molecular Cell Biology, and Centre for Biomedical Genetics, Leiden University Medical Center, RC Leiden, The Netherlands.

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http://www.hh.um.es/Abstracts/Vol_26/26_9/26_9_1219.htm
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http://dx.doi.org/10.14670/HH-26.1219DOI Listing
September 2011

Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins.

Blood 2008 Apr 31;111(7):3607-14. Epub 2008 Jan 31.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2007-07-103077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275024PMC
April 2008

The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).

J Biol Chem 2007 Aug 19;282(32):23603-12. Epub 2007 Jun 19.

Institute for Clinical Immunology and Transfusion Medicine, Justus Liebig University, Langhansstrasse 7, Giessen D-35392, Germany.

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http://dx.doi.org/10.1074/jbc.M701120200DOI Listing
August 2007

Regulation of vascular endothelial permeability by junctional adhesion molecules (JAM).

Thromb Haemost 2007 Aug;98(2):327-32

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive, Rm 4B17, Bethesda, MD 20892, USA.

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August 2007

Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts.

J Exp Med 2006 Nov 20;203(12):2703-14. Epub 2006 Nov 20.

Experimental Immunology Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20051730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118160PMC
November 2006

The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions.

J Biol Chem 2005 Oct 23;280(43):36326-33. Epub 2005 Aug 23.

Experimental Immunology Branch, NCI, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M505059200
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http://dx.doi.org/10.1074/jbc.M505059200DOI Listing
October 2005