Valeria Pittalà

Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy; Center for Research in Ocular Pharmacology-CERFO, University of Catania, Catania, Italy. Electronic address:

View Article and Find Full Text PDF

May 2020

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells.

Authors:

Valeria Ciaffaglione Sebastiano Intagliata Valeria Pittalà Agostino Marrazzo Valeria Sorrenti Luca Vanella Antonio Rescifina Giuseppe Floresta Ameera Sultan Khaled Greish Loredana Salerno

Int J Mol Sci 2020 Mar 11;21(6). Epub 2020 Mar 11.

Department of Drug Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.

View Article and Find Full Text PDF

March 2020

Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells.

Authors:

Carlo Castruccio Castracani Lucia Longhitano Alfio Distefano Michelino Di Rosa Valeria Pittalà Gabriella Lupo Massimo Caruso Daniela Corona Daniele Tibullo Giovanni Li Volti

Mol Neurobiol 2020 May 27;57(5):2436-2446. Epub 2020 Feb 27.

Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 97, 95125, Catania, Italy.

View Article and Find Full Text PDF

May 2020

The analgesic potential of glycosides derived from medicinal plants.

Authors:

Haroon Khan Aini Pervaiz Sebastiano Intagliata Niranjan Das Kalyan C Nagulapalli Venkata Atanas G Atanasov Agnieszka Najda Seyed Mohammad Nabavi Dongdong Wang Valeria Pittalà Anupam Bishayee

Daru 2020 Jun 14;28(1):387-401. Epub 2020 Feb 14.

Lake Erie College of Osteopathic Medicine, 5000 Lakewood Ranch Boulevard, Bradenton, FL, 34211, USA.

View Article and Find Full Text PDF

June 2020

Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation.

Authors:

Mariarita Spampinato Giuseppe Sferrazzo Valeria Pittalà Michelino Di Rosa Luca Vanella Loredana Salerno Valeria Sorrenti Giuseppe Carota Nunziatina Parrinello Marco Raffaele Daniele Tibullo Giovanni Li Volti Ignazio Barbagallo

Mol Biol Rep 2020 Mar 13;47(3):1949-1964. Epub 2020 Feb 13.

Department of Drug Science, Biochemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy.

View Article and Find Full Text PDF

March 2020

Ginseng and heme oxygenase-1: The link between an old herb and a new protective system.

Authors:

Giuseppe Carota Marco Raffaele Valeria Sorrenti Loredana Salerno Valeria Pittalà Sebastiano Intagliata

Fitoterapia 2019 Nov 17;139:104370. Epub 2019 Oct 17.

Department of Drug Science, Medicinal Chemistry Section, University of Catania, 95125 Catania, Italy. Electronic address:

View Article and Find Full Text PDF

November 2019

Progress in the development of more effective and safer analgesics for pain management.

Authors:

Rita Turnaturi Santina Chiechio Loredana Salerno Antonio Rescifina Valeria Pittalà Giuseppina Cantarella Emilia Tomarchio Carmela Parenti Lorella Pasquinucci

Eur J Med Chem 2019 Dec 16;183:111701. Epub 2019 Sep 16.

Department of Drug Sciences, Medicinal Chemistry Section, University of Catania, Viale A. Doria 6, 95125, Catania, Italy.

View Article and Find Full Text PDF

December 2019

Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.

Authors:

Sebastiano Intagliata Loredana Salerno Valeria Ciaffaglione Carmen Leonardi Antonino N Fallica Giuseppe Carota Emanuele Amata Agostino Marrazzo Valeria Pittalà Giuseppe Romeo

Eur J Med Chem 2019 Dec 17;183:111703. Epub 2019 Sep 17.

Department of Drug Sciences, University of Catania, Viale A. Doria 6, 95125, Catania, Italy.

View Article and Find Full Text PDF

December 2019

[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT receptor.

Authors:

Giuseppe Romeo Loredana Salerno Valeria Pittalà Marialuisa Candido Sebastiano Intagliata Emanuele Amata Mario Salmona Alfredo Cagnotto Antonio Rescifina Giuseppe Floresta Maria Nunziata Modica

Eur J Med Chem 2019 Dec 10;183:111690. Epub 2019 Sep 10.

Dipartimento di Scienze del Farmaco, Università di Catania, viale A. Doria 6, 95125, Catania, Italy.

View Article and Find Full Text PDF

December 2019

Synthesis, and studies of HO-1 inducers and lung antifibrotic agents.

Authors:

Valeria Pittalà Luca Vanella Chiara Bianca Maria Platania Loredana Salerno Marco Raffaele Emanuele Amata Agostino Marrazzo Giuseppe Floresta Giuseppe Romeo Khaled Greish Sebastiano Intagliata Claudio Bucolo Valeria Sorrenti

Future Med Chem 2019 07;11(13):1523-1536

Department of Drug Sciences, University of Catania, Viale A. Doria 6, Sicily, 95125, Italy.

View Article and Find Full Text PDF

July 2019

Heme Oxygenase-1 Inhibition Sensitizes Human Prostate Cancer Cells towards Glucose Deprivation and Metformin-Mediated Cell Death.

Authors:

Marco Raffaele Valeria Pittalà Veronica Zingales Ignazio Barbagallo Loredana Salerno Giovanni Li Volti Giuseppe Romeo Giuseppe Carota Valeria Sorrenti Luca Vanella

Int J Mol Sci 2019 May 27;20(10). Epub 2019 May 27.

Department of Drug Science, Biochemistry Section, University of Catania, 95125 Catania, Italy.

View Article and Find Full Text PDF

May 2019

Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats.

Authors:

Valeria Sorrenti Marco Raffaele Luca Vanella Rosaria Acquaviva Loredana Salerno Valeria Pittalà Sebastiano Intagliata Claudia Di Giacomo

Int J Mol Sci 2019 May 17;20(10). Epub 2019 May 17.

Department of Drug Science, Biochemistry Section, University of Catania, 95125 Catania, Italy.

View Article and Find Full Text PDF

May 2019

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.

Authors:

Giuseppe Romeo Orazio Prezzavento Sebastiano Intagliata Valeria Pittalà Maria N Modica Agostino Marrazzo Rita Turnaturi Carmela Parenti Santina Chiechio Emanuela Arena Agata Campisi Giovanni Sposito Loredana Salerno

Eur J Med Chem 2019 Jul 21;174:226-235. Epub 2019 Apr 21.

Department of Drug Sciences, University of Catania, Viale A. Doria 6, 95125, Catania, Italy.

View Article and Find Full Text PDF

July 2019

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application.

Authors:

Loredana Salerno Giuseppe Floresta Valeria Ciaffaglione Davide Gentile Fatima Margani Rita Turnaturi Antonio Rescifina Valeria Pittalà

Eur J Med Chem 2019 Apr 12;167:439-453. Epub 2019 Feb 12.

Department of Drug Sciences, University of Catania, V.le A. Doria 6, 95125, Catania, Italy. Electronic address:

View Article and Find Full Text PDF

April 2019

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.

Authors:

Giuseppe Floresta Emanuele Amata Davide Gentile Giuseppe Romeo Agostino Marrazzo Valeria Pittalà Loredana Salerno Antonio Rescifina

Mar Drugs 2019 Feb 12;17(2). Epub 2019 Feb 12.

Department of Drug Sciences, University of Catania, V.le A. Doria, 95125 Catania, Italy.

View Article and Find Full Text PDF

February 2019

Curcumin, the golden spice in treating cardiovascular diseases.

Authors:

Hong Li Antoni Sureda Hari Prasad Devkota Valeria Pittalà Davide Barreca Ana Sanches Silva Devesh Tewari Suowen Xu Seyed Mohammad Nabavi

Biotechnol Adv 2020 Jan - Feb;38:107343. Epub 2019 Feb 1.

Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran 14359-16471, Iran. Electronic address:

View Article and Find Full Text PDF

February 2020

The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice.

Authors:

Khaled Greish Abdulelah Abdullah Alqahtani Abdulla Falah Alotaibi Ahmed Mohamed Abdulla Aysha Tariq Bukelly Fanar Mohammed Alsobyani Ghazi Hamad Alharbi Israa Saeed Alkiyumi Majed Mutlaq Aldawish Turki Fahad Alshahrani Valeria Pittalà Sebastien Taurin Amer Kamal

Int J Environ Res Public Health 2019 01 8;16(1). Epub 2019 Jan 8.

Department of Physiology, Arabian Gulf University, Manama 329, Kingdom of Bahrain.

View Article and Find Full Text PDF

January 2019

Targeting STATs in neuroinflammation: The road less traveled!

Pharmacol Res 2019 03 11;141:73-84. Epub 2018 Dec 11.

Department of Pharmacology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

View Article and Find Full Text PDF

March 2019

Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity.

Authors:

Houman Alimoradi Khaled Greish Anita Barzegar-Fallah Lama Alshaibani Valeria Pittalà

Int J Nanomedicine 2018 20;13:7771-7787. Epub 2018 Nov 20.

Department of Drug Science, University of Catania, Catania, Italy.

View Article and Find Full Text PDF

January 2019

Curcumin⁻Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer.

Authors:

Khaled Greish Valeria Pittalà Sebastien Taurin Safa Taha Fatemah Bahman Aanchal Mathur Anfal Jasim Fatima Mohammed Ibrahim M El-Deeb Salim Fredericks Fiza Rashid-Doubell

Nanomaterials (Basel) 2018 Nov 1;8(11). Epub 2018 Nov 1.

Department of Basic Medical Sciences, Royal College of Surgeons in Ireland (RCSI), Medical University of Bahrain, Busaiteen 221, Bahrain.

View Article and Find Full Text PDF

November 2018

Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer.

Authors:

Khaled Greish Aanchal Mathur Reem Al Zahrani Sara Elkaissi Muna Al Jishi Osama Nazzal Safa Taha Valeria Pittalà Sebastien Taurin

J Control Release 2018 12 25;291:184-195. Epub 2018 Oct 25.

Department of Molecular Medicine, and Nanomedicine Unit, Princess Al-Jawhara Center for Molecular Medicine and inherited disorders, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA.

View Article and Find Full Text PDF

December 2018