Valeria Orrú

Valeria Orrú

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Valeria Orrú

Valeria Orrú

Publications by authors named "Valeria Orrú"

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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Authors:
Mengzhen Liu Yu Jiang Robbee Wedow Yue Li David M Brazel Fang Chen Gargi Datta Jose Davila-Velderrain Daniel McGuire Chao Tian Xiaowei Zhan Hélène Choquet Anna R Docherty Jessica D Faul Johanna R Foerster Lars G Fritsche Maiken Elvestad Gabrielsen Scott D Gordon Jeffrey Haessler Jouke-Jan Hottenga Hongyan Huang Seon-Kyeong Jang Philip R Jansen Yueh Ling Reedik Mägi Nana Matoba George McMahon Antonella Mulas Valeria Orrù Teemu Palviainen Anita Pandit Gunnar W Reginsson Anne Heidi Skogholt Jennifer A Smith Amy E Taylor Constance Turman Gonneke Willemsen Hannah Young Kendra A Young Gregory J M Zajac Wei Zhao Wei Zhou Gyda Bjornsdottir Jason D Boardman Michael Boehnke Dorret I Boomsma Chu Chen Francesco Cucca Gareth E Davies Charles B Eaton Marissa A Ehringer Tõnu Esko Edoardo Fiorillo Nathan A Gillespie Daniel F Gudbjartsson Toomas Haller Kathleen Mullan Harris Andrew C Heath John K Hewitt Ian B Hickie John E Hokanson Christian J Hopfer David J Hunter William G Iacono Eric O Johnson Yoichiro Kamatani Sharon L R Kardia Matthew C Keller Manolis Kellis Charles Kooperberg Peter Kraft Kenneth S Krauter Markku Laakso Penelope A Lind Anu Loukola Sharon M Lutz Pamela A F Madden Nicholas G Martin Matt McGue Matthew B McQueen Sarah E Medland Andres Metspalu Karen L Mohlke Jonas B Nielsen Yukinori Okada Ulrike Peters Tinca J C Polderman Danielle Posthuma Alexander P Reiner John P Rice Eric Rimm Richard J Rose Valgerdur Runarsdottir Michael C Stallings Alena Stančáková Hreinn Stefansson Khanh K Thai Hilary A Tindle Thorarinn Tyrfingsson Tamara L Wall David R Weir Constance Weisner John B Whitfield Bendik Slagsvold Winsvold Jie Yin Luisa Zuccolo Laura J Bierut Kristian Hveem James J Lee Marcus R Munafò Nancy L Saccone Cristen J Willer Marilyn C Cornelis Sean P David David A Hinds Eric Jorgenson Jaakko Kaprio Jerry A Stitzel Kari Stefansson Thorgeir E Thorgeirsson Gonçalo Abecasis Dajiang J Liu Scott Vrieze

Nat Genet 2019 02 14;51(2):237-244. Epub 2019 Jan 14.

Department of Psychology, University of Minnesota Twin Cities, Minneapolis, MN, USA.

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http://www.nature.com/articles/s41588-018-0307-5
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http://dx.doi.org/10.1038/s41588-018-0307-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358542PMC
February 2019

Cooperative translational control of polymorphic BAFF by NF90 and miR-15a.

Nucleic Acids Res 2018 12;46(22):12040-12051

Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1093/nar/gky866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294513PMC
December 2018

Genetic variants in mRNA untranslated regions.

Wiley Interdiscip Rev RNA 2018 07 26;9(4):e1474. Epub 2018 Mar 26.

Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy.

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http://dx.doi.org/10.1002/wrna.1474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002891PMC
July 2018

CD8CD28CD127CD39 regulatory T-cell expansion: A new possible pathogenic mechanism for HIV infection?

J Allergy Clin Immunol 2018 Jun 2;141(6):2220-2233.e4. Epub 2017 Nov 2.

Centre of Excellence for Biomedical Research, University of Genoa, Genoa, Italy; Department of Internal Medicine, University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliero Universitaria San Martino, IST-Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.08.021DOI Listing
June 2018

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

N Engl J Med 2017 04;376(17):1615-1626

From Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato (M.S., V.O., M.L.I., M. Pitzalis, M. Pala, C.S., V.F., M.F., M. Deiana, I.A., E.P., A. Mulas, M.G.P., M. Lobina, S.L., Mara Marongiu, V.S., Michele Marongiu, G.S., F.B., A. Maschio, F.D., M. Dei, F.V., S.O., A.A., M.B.W., A. Meloni, S. Sanna, E.F., M.Z., F.C.), Center for Advanced Studies, Research, and Development in Sardinia, Parco Scientifico e Tecnologico della Sardegna (I.Z., M.F., R.C., G. Cuccuru), Struttura Complessa Disciplina di Ematologia e Centro Trapianto Cellule Staminali Emopoietiche Wilma Deplano, Ospedale Oncologico di Riferimento Regionale Armando Businco (M. Pani), Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Università di Cagliari (E.C., J.F., G. Coghe, L.L., G. Fenu), Azienda Ospedaliera Brotzu, S.C. Neurologia (P.F., M. Melis), Division of Rheumatology, University and University Hospital of Cagliari (M. Piga, A. Mathieu), Department of Medical Sciences M. Aresu, University of Cagliari (D.F., S.D.G., M.G.M.), Azienda Ospedaliera Brotzu, U.S. Gastroenterologia Pediatrica Ospedale Pediatrico Microcitemico A. Cao (M.C.), and Nephrology, Dialysis, and Transplantation Unit, Giuseppe Brotzu Hospital (A.P.), Cagliari, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari (M.F., F.P., F.C.), Unit of Neurology, Department of Clinical and Experimental Medicine, University of Sassari (G. Farina, G.R.), and Servizio Trasfusionale (M.A.S.) and Clinica Medica (A.D.), Azienda Ospedaliero Universitaria di Sassari, Sassari, Neurology B, Department of Neurological, Biomedical, and Movement Sciences, University of Verona, Verona (G. Farina), Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases, University of Eastern Piedmont, Novara (N.B., S.D.), SC Neurologia, Dipartimento di Scienze Mediche, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo (M. Leone), Don C. Gnocchi Foundation IRCCS (F.R.G.), and Referral Center for Systemic Autoimmune Diseases Fondazione IRCCS Cá Granda Ospedale Maggiore Policlinico and University of Milan (M. Marchini), Milan, and Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche e Ospedali Riuniti, Ancona (M.G.D.) - all in Italy; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore (M.L.I., M.G., D.S.); the Department of Clinical Neurosciences (M.B., S. Sawcer) and JDRF-Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research (J.A.T.), University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna (I.K., I.L.B., T.O., J.H.), Institute of Environmental Medicine (L.A.) and Institute of Environmental Medicine, Unit of Immunology and Chronic Disease (M.E.A.R.), Karolinska Institute, and Center for Occupational and Environmental Medicine, Stockholm County Council (L.A.), Stockholm; Department of Functional Biology, University of Oviedo, Oviedo (A.S.), Rheumatology Department, Hospital Universitario 12 de Octubre, Madrid (P.E.C.), Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Seville (M.J.C.-P.), Laboratorio de Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela (A.G.), and Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada (M.E.A.R.) - all in Spain; Department of Human Genetics, University of Chicago, Chicago (J.H.M., J.N.); Centro Hospitalar do Porto-Hospital Santo Antonio and Unit for Multidisciplinary Research in Biomedicine-Unidade Multidisciplinar de Investigação Biomédica, Porto, Portugal (B.M.S.); Departments of Pathology and Genetics, Stanford University, Stanford, CA (S.B.M.); and Center for Statistical Genetics, University of Michigan, Ann Arbor (G.R.A.).

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http://dx.doi.org/10.1056/NEJMoa1610528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605835PMC
April 2017

Depressive symptoms, thyroid hormone and autoimmunity in a population-based cohort from Sardinia.

J Affect Disord 2016 Feb 26;191:82-7. Epub 2015 Nov 26.

Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Cagliari, Italy; Department of Biomedical Sciences, Azienda Ospedaliero-Universitaria di Sassari, Sassari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2015.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715961PMC
February 2016

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

PLoS One 2014 3;9(2):e86677. Epub 2014 Feb 3.

Division of Cellular Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America ; Institute for Genetic Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://www.lupusresearch.org/lupus-research/scientific-publi
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http://dx.plos.org/10.1371/journal.pone.0086677
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086677PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911918PMC
December 2014

Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain.

Biochemistry 2009 Aug;48(31):7525-32

Institute for Genetic Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1021/bi900332fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113683PMC
August 2009

Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study.

J Med Chem 2008 Aug 8;51(15):4790-5. Epub 2008 Jul 8.

Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1021/jm800101wDOI Listing
August 2008

Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.

Diabetes 2008 Jan 12;57(1):229-34. Epub 2007 Oct 12.

Dipartimento di Scienze Biomediche, University of Sassari, Sassari, Italy.

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http://dx.doi.org/10.2337/db07-0289DOI Listing
January 2008

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant.

Nat Genet 2005 Dec 6;37(12):1317-9. Epub 2005 Nov 6.

Program on Inflammatory Disease Research, Infectious and Inflammatory Disease Center, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/ng1673DOI Listing
December 2005