Publications by authors named "Valentina Nardi"

84Publications

Across Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections.

Front Endocrinol (Lausanne) 2020 24;11:480. Epub 2020 Sep 24.

Laboratory of Regenerative Hematopoiesis, Institute of Bioengineering and Institute for Experimental Cancer Research, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.3389/fendo.2020.00480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542184PMC
September 2020

Inflammatory Myofibroblastic Tumors associated with the placenta, a series of 9 cases.

Hum Pathol 2020 Sep 21. Epub 2020 Sep 21.

Massachusetts General Hospital, Department of Pathology, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2020.09.005DOI Listing
September 2020

Case 10-2020: An 83-Year-Old Man with Pancytopenia and Acute Renal Failure.

N Engl J Med 2020 03;382(13):1258-1266

From the Departments of Medicine (D.B.S., R.S.K.L., S.E.T.), Radiology (E.W.Z.), and Pathology (V.N., S.E.T.), Massachusetts General Hospital, and the Departments of Medicine (D.B.S., R.S.K.L., S.E.T.), Radiology (E.W.Z.), and Pathology (V.N., S.E.T.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1916250DOI Listing
March 2020

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors.

Bioorg Med Chem Lett 2020 04 22;30(8):127052. Epub 2020 Feb 22.

Departments of Chemistry and Biology, IRBM Spa, Via Pontina km 30, 600, 00071 Pomezia, Rome, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2020.127052DOI Listing
April 2020

Case 37-2019: A 20-Month-Old Boy with Severe Anemia.

N Engl J Med 2019 Nov;381(22):2158-2167

From the Departments of Pediatrics (B.M.C., A.M.R., M.S.H.), Radiology (R.S.), and Pathology (V.N.), Massachusetts General Hospital, and the Departments of Pediatrics (B.M.C., A.M.R., M.S.H.), Radiology (R.S.), and Pathology (V.N.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1904048DOI Listing
November 2019

Case 35-2019: A 66-Year-Old Man with Pancytopenia and Rash.

N Engl J Med 2019 Nov;381(20):1951-1960

From the Departments of Medicine (M.V.M., M.B.L.) and Pathology (K.M.C., V.N.), Massachusetts General Hospital, and the Departments of Medicine (M.V.M., M.B.L.) and Pathology (K.M.C., V.N.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1909627DOI Listing
November 2019

Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions.

Mod Pathol 2020 04 22;33(4):560-565. Epub 2019 Oct 22.

Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41379-019-0382-xDOI Listing
April 2020

Premalignant Clonal Hematopoietic Proliferations.

Am J Clin Pathol 2019 08;152(3):347-358

Department of Pathology, Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1093/ajcp/aqz079DOI Listing
August 2019

Case 35-2018: A Woman with Back Pain and a Remote History of Breast Cancer. Reply.

Authors:
Valentina Nardi

N Engl J Med 2019 04;380(15):e22

Massachusetts General Hospital, Boston, MA.

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http://www.nejm.org/doi/10.1056/NEJMc1817336
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http://dx.doi.org/10.1056/NEJMc1817336DOI Listing
April 2019

Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms.

Hum Pathol 2019 04 27;86:1-11. Epub 2018 Dec 27.

Department of Pathology, Massachusetts General Hospital, 02114 Boston, MA, USA; Harvard Medical School, 02114 Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.11.022DOI Listing
April 2019

Feasibility of Perioperative Micro-Computed Tomography of Human Lung Cancer Specimens: A Pilot Study.

Arch Pathol Lab Med 2019 03 20;143(3):319-325. Epub 2018 Nov 20.

From the Departments of Radiology (Mr Troschel and Drs Gottumukkala, Mario, Yang, Shepard, Fintelmann), Pathology (Mr DiCorpo and Drs Nardi, Michaelson, and Hariri), and Surgery (Drs Ott, Wright, Muniappan, and Lanuti), Massachusetts General Hospital, Boston; and Universitätsklinikum Münster, Münster, Germany (Mr Troschel). Mr Troschel and Dr Gottumukkala contributed equally to this manuscript and share first authorship. Drs Hariri and Fintelmann contributed equally to this manuscript and share senior authorship.

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http://dx.doi.org/10.5858/arpa.2018-0249-OADOI Listing
March 2019

Case 35-2018: A 68-Year-Old Woman with Back Pain and a Remote History of Breast Cancer.

N Engl J Med 2018 Nov;379(20):1946-1953

From the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Massachusetts General Hospital, and the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1616400DOI Listing
November 2018

A Nanopore Sequencing-Based Assay for Rapid Detection of Gene Fusions.

J Mol Diagn 2019 01 28;21(1):58-69. Epub 2018 Sep 28.

Department of Pathology, Massachusetts General Hospital, Boston; and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.08.003DOI Listing
January 2019

"Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism.

Mol Cancer Res 2018 12 23;16(12):1826-1833. Epub 2018 Aug 23.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279489PMC
December 2018

Uric acid is an independent predictor of cardiac allograft vasculopathy after heart transplantation.

J Heart Lung Transplant 2018 09 1;37(9):1083-1092. Epub 2018 May 1.

Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2018.04.017DOI Listing
September 2018

Laboratory testing in BCR-ABL1-like (Philadelphia-like) B-lymphoblastic leukemia/lymphoma.

Am J Hematol 2018 07 15;93(7):971-977. Epub 2018 May 15.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.25126DOI Listing
July 2018

Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsins.

Bioorg Med Chem Lett 2018 05 26;28(9):1540-1544. Epub 2018 Mar 26.

Department of Chemistry, IRBM Science Park, Via Pontina km 30, 600, Pomezia 00071, Rome, Italy.

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http://dx.doi.org/10.1016/j.bmcl.2018.03.069DOI Listing
May 2018

MET Amplification in Esophageal Squamous Carcinoma.

Int J Surg Pathol 2018 12 19;26(8):731-732. Epub 2018 Mar 19.

1 Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/1066896918764301DOI Listing
December 2018

Syphilis of the Aerodigestive Tract.

Am J Surg Pathol 2018 04;42(4):472-478

Department of Pathology, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000987DOI Listing
April 2018

Electromagnetic fields in neonatal incubators: the reasons for an alert.

J Matern Fetal Neonatal Med 2019 Feb 23;32(4):695-699. Epub 2017 Oct 23.

b Department of Pediatrics , University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1080/14767058.2017.1390559DOI Listing
February 2019

GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas.

Mod Pathol 2017 12 4;30(12):1720-1727. Epub 2017 Aug 4.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2017.88DOI Listing
December 2017

Case 5-2017. A 19-Year-Old Man with Hematuria and a Retroperitoneal Mass.

N Engl J Med 2017 02;376(7):684-692

From the Departments of Urology (M.L.B.), Medicine (J.S.A.), Radiology (K.C.C.), and Pathology (V.N.), Massachusetts General Hospital, and the Departments of Urology (M.L.B.), Medicine (J.S.A.), Radiology (K.C.C.), and Pathology (V.N.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1610100DOI Listing
February 2017

Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation.

Am J Surg Pathol 2017 Mar;41(3):299-312

*Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI †Department of Pathology, The James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston ‡‡Department of Pathology, North Shore Medical Center, Salem, MA ‡Department of Anatomical Pathology, St Vincent's Hospital, Melbourne, Vic., Australia §Institut Universitaire de Pathologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland ∥Department of Laboratory Medicine, University of Washington, Seattle, WA ¶Department of Pathology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea #Herbert Wertheim College of Medicine, Florida International University, Miami, FL **Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN ††Department of Pathology, Holmes Regional Medical Center, Melbourne, FL §§NeoGenomics Laboratories, Aliso Viejo, CA ∥∥Department of Pathology, Johns Hopkins University School of Medicine, Baltimore ¶¶Laboratory of Pathology, Hematopathology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/PAS.0000000000000775DOI Listing
March 2017

Diagnostic work-up of acute myeloid leukemia.

Am J Hematol 2017 Mar 3;92(3):317-321. Epub 2017 Feb 3.

Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/ajh.24648
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http://dx.doi.org/10.1002/ajh.24648DOI Listing
March 2017

EBV-negative monomorphic B-cell post-transplant lymphoproliferative disorders are pathologically distinct from EBV-positive cases and frequently contain TP53 mutations.

Mod Pathol 2016 10 22;29(10):1200-11. Epub 2016 Jul 22.

The James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, and The Department of Pathology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.130DOI Listing
October 2016

Primary Endometrial Marginal Zone Lymphoma (MALT Lymphoma): A Unique Clinicopathologic Entity.

Am J Surg Pathol 2016 09;40(9):1217-23

*Department of Pathology, Massachusetts General Hospital †Department of Pathology, The Brigham and Women's Hospital, Harvard Medical School Boston, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000683DOI Listing
September 2016

Genetic Testing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Surg Pathol Clin 2016 Mar;9(1):143-63

Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.path.2015.10.004DOI Listing
March 2016

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.

Cancer Discov 2015 Oct 30;5(10):1058-71. Epub 2015 Jul 30.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Broad Institute of Harvard University and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592453PMC
October 2015

Routine conventional karyotyping of lymphoma staging bone marrow samples does not contribute clinically relevant information.

Am J Hematol 2015 Jun 3;90(6):529-33. Epub 2015 May 3.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.24008DOI Listing
June 2015

A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.

Cancer Discov 2014 May 14;4(5):554-63. Epub 2014 Mar 14.

1Whitehead Institute for Biomedical Research; 2Howard Hughes Medical Institute and Department of Biology, MIT; 3Broad Institute of Harvard and MIT; 4The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge; 5Department of Pathology, Massachusetts General Hospital Cancer Center; and 6Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012430PMC
May 2014

Case records of the Massachusetts General Hospital. Case 24-2013. A 53-year-old woman with erythroderma, pruritus, and lymphadenopathy.

N Engl J Med 2013 Aug;369(6):559-69

Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1056/NEJMcpc1201415DOI Listing
August 2013

Parasitic infection by larval helminths in Antarctic fishes: pathological changes and impact on the host body condition index.

Dis Aquat Organ 2013 Jul;105(2):139-48

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.3354/dao02626DOI Listing
July 2013

Merkel cell carcinoma: 30-year experience from a single institution.

Ann Surg Oncol 2013 Apr 1;20(4):1365-73. Epub 2012 Dec 1.

Department of Surgery, Massachusetts General Hospital, Harvard Medical School, YAW 7B, 55 Fruit Street, Boston, MA 02114, USA.

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http://www.researchgate.net/profile/Genevieve_Boland/publica
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http://dx.doi.org/10.1245/s10434-012-2779-3DOI Listing
April 2013

Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients.

Clin Cancer Res 2012 Oct 21;18(20):5761-72. Epub 2012 Aug 21.

Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759991PMC
October 2012

Administration of vincristine in a patient with Machado-Joseph disease.

Oncology 2012 15;82(3):165-7. Epub 2012 Mar 15.

Department of Medicine, Haematology and Clinical Immunology, University of Padua School of Medicine, Padua, Italy.

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https://www.karger.com/Article/FullText/336602
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http://dx.doi.org/10.1159/000336602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701890PMC
June 2012

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment.

Nature 2009 Jul 10;460(7252):259-63. Epub 2009 Jun 10.

Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana Farber Cancer Institute, Massachusetts 02115, USA.

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http://www.nature.com/articles/nature08099
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http://dx.doi.org/10.1038/nature08099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831539PMC
July 2009

FAK silencing inhibits leukemogenesis in BCR/ABL-transformed hematopoietic cells.

Am J Hematol 2009 May;84(5):273-8

Department of Pathology, Joint Program in Transfusion Medicine, Children's Hospital Boston, Karp Research Building, Room 10217, One Blackfan Circle, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/ajh.21381DOI Listing
May 2009

Farnesyl transferase inhibitor resistance probed by target mutagenesis.

Blood 2007 Sep 29;110(6):2102-9. Epub 2007 May 29.

Division of Hematology/Oncology, Children's Hospital Boston, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1182/blood-2006-12-064907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976354PMC
September 2007

Mechanisms and implications of imatinib resistance mutations in BCR-ABL.

Curr Opin Hematol 2004 Jan;11(1):35-43

Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1097/00062752-200401000-00006DOI Listing
January 2004

A screen to identify drug resistant variants to target-directed anti-cancer agents.

Biol Proced Online 2003;5:204-210. Epub 2003 Oct 24.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Division of Pediatric Hematology/Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115 USA. Children's Hospital, 300 Longwood Ave, Boston, MA 02115. USA.

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http://dx.doi.org/10.1251/bpo63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC248481PMC
October 2003