Dr. Valdis Pirags, MD, PhD - University of Latvia - Professor of Medicine, Senator

Dr. Valdis Pirags

MD, PhD

University of Latvia

Professor of Medicine, Senator

Riga | Latvia

Main Specialties: Internal Medicine

Additional Specialties: Medicine


Top Author

Dr. Valdis Pirags, MD, PhD - University of Latvia - Professor of Medicine, Senator

Dr. Valdis Pirags

MD, PhD

Introduction

Dr. Valdis Pirags, MD is Professor of Medicine at the University of Latvia and the Head of the Clinic of Internal Medicine at the Pauls Stradi?š Clinical University Hospital in Riga, Latvia. He graduated the Medical Academy of Latvia (now: Stradi?š University of Riga) in 1990 and was awarded his PhD (Dr. med. magna cum laude) from the Ruhr-University of Bochum, Germany in 1995. He first became interested in genetics of multifactorial diseases while undertaking studies on molecular pathogenesis of late diabetic complications under supervision of Professor A.F.H. Pfeiffer. On his return to Latvia in 1996, he continued his work on molecular medicine and genetics of endocrine diseases at the Pauls Stradi?š Clinical University Hospital. These studies embrace the effects of hyperglycemia on cellular signaling pathways and genetics of type 2 diabetes mellitus. He was recipient of the Karl Oberdisse award for the best first author publication in 1996 and the Distinguished Research Award from the Kuwait Foundation for the Advancement of Sciences (KFAS) in 2003. More recently, he has also been working on epidemiology of diabetes mellitus in Latvia and creation of the Genome Database of the Latvian Population.

Dr. Pirags has authored or coauthored more than 150 original scientific articles, book chapters, and abstracts in Latvian and international journals. He is serving as a peer reviewer or member of the Editorial Board of several international medical journals. He organized several Postgraduate Courses in Clinical Endocrinology of the European Federation of Endocrine Societies (EFES) and the European Society of Endocrinology (ESE) in across Europe since 2003.

Professor Pirags served as an independent expert for the evaluation of the 6th and 7th Framework Program projects at the European Commission, a member of the Working Party on Research on Stored Human Biological Materials at the Steering Committee on Bioethics (CDBI-CO-GT2biomat) at the Council of Europe, member of the Forum of Research Managers in the Field of Genome Research at the European Commission, and member of the Executive Committee of ScanBalt BioRegion. He was member of the Executive Committee of the European Society of Endocrinology and Council member of the European Association for the Study of Diabetes (EASD) for 2006-2009. His is the director of the Latvian National Research Programme on Clinical Medicine and Public Health since 2009.

Primary Affiliation: University of Latvia - Riga , Latvia

Specialties:

Additional Specialties:

Research Interests:


View Dr. Valdis Pirags’s Resume / CV

Education

Jul 1995
Ruhr University Bochum
Jun 1990
Riga Medical Institute
Jun 1984
University of Latvia

Experience

Sep 2005
Latvian National Research Programme on Biomedicine and Public Health
Director
Sep 1999
European Association for the Study of Diabetes
Council Member
Apr 1996
European Society of Endocrinology
Executive Committee
Founding Member

Publications

28Publications

460Reads

471Profile Views

869PubMed Central Citations

Polymorphisms in MEN1 and DRD2 genes are associated with the occurrence and characteristics of pituitary adenomas.

Eur J Endocrinol 2016 Aug 16;175(2):145-53. Epub 2016 May 16.

Latvian Biomedical Research and Study CentreRiga, Latvia

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http://dx.doi.org/10.1530/EJE-15-0879DOI Listing
August 2016
12 Reads
1 Citation
4.070 Impact Factor

Functional Characteristics of Multipotent Mesenchymal Stromal Cells from Pituitary Adenomas.

Stem Cells Int 2016 2;2016:7103720. Epub 2016 Jun 2.

Latvian Biomedical Research and Study Centre, Ratsupites Street 1 k-1, Riga LV-1067, Latvia.

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http://dx.doi.org/10.1155/2016/7103720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909910PMC
June 2016
8 Reads
2 Citations
2.810 Impact Factor

The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity.

Mol Biol Rep 2014 Mar 3;41(3):1491-500. Epub 2014 Jan 3.

Latvian Biomedical Research and Study Centre, Ratsupites Str. 1, 1067, Riga, Latvia.

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http://dx.doi.org/10.1007/s11033-013-2994-4DOI Listing
March 2014
3 Reads
3 Citations
2.024 Impact Factor

Association of reduced glyoxalase 1 activity and painful peripheral diabetic neuropathy in type 1 and 2 diabetes mellitus patients.

J Diabetes Complications 2013 May-Jun;27(3):262-7. Epub 2013 Jan 23.

Latvian Institute of Organic Synthesis, Laboratory of Pharmaceutical Pharmacology, Riga, Latvia.

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http://dx.doi.org/10.1016/j.jdiacomp.2012.12.002DOI Listing
November 2013
34 Reads
6 Citations
1.925 Impact Factor

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes.

Gene 2013 Sep 13;527(2):462-8. Epub 2013 Jul 13.

Latvian Biomedical Research and Study Centre, Ratsupites Street 1, LV-1067 Riga, Latvia.

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http://dx.doi.org/10.1016/j.gene.2013.06.079DOI Listing
September 2013
8 Reads
8 Citations
2.140 Impact Factor

Identification of glyoxalase 1 polymorphisms associated with enzyme activity.

Gene 2013 Feb 29;515(1):140-3. Epub 2012 Nov 29.

Latvian Biomedical Research and Study Centre, Ratsupites str 1, Riga, LV-1067, Latvia.

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http://dx.doi.org/10.1016/j.gene.2012.11.009DOI Listing
February 2013
7 Reads
6 Citations
2.140 Impact Factor

Seasonal iodine deficiency in Latvian school children.

Thyroid 2012 Oct 4;22(10):1088-9. Epub 2012 Sep 4.

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http://dx.doi.org/10.1089/thy.2011.0506DOI Listing
October 2012
10 Reads
1 Citation
4.493 Impact Factor

Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population.

Mol Biol Rep 2012 Feb 4;39(2):1917-25. Epub 2011 Jun 4.

Latvian Biomedical Research and Study Centre, Ratsupites str. 1, Riga 1067, Latvia.

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http://dx.doi.org/10.1007/s11033-011-0938-4DOI Listing
February 2012
6 Reads
6 Citations
2.024 Impact Factor

A nonsynonymous variant I248L of the adenosine A3 receptor is associated with coronary heart disease in a Latvian population.

DNA Cell Biol 2011 Nov 15;30(11):907-11. Epub 2011 Jun 15.

Latvian Biomedical Research and Study Centre, Riga, Latvia.

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http://dx.doi.org/10.1089/dna.2011.1230DOI Listing
November 2011
7 Reads
4 Citations
2.060 Impact Factor

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly.

Eur J Endocrinol 2011 Oct 2;165(4):517-25. Epub 2011 Aug 2.

Latvian Biomedical Research and Study Centre, Ratsupites Street 1, LV-1067 Riga, Latvia.

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http://dx.doi.org/10.1530/EJE-11-0416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178914PMC
October 2011
6 Reads
4 Citations
4.070 Impact Factor

Pioglitazone use in combination with insulin in the prospective pioglitazone clinical trial in macrovascular events study (PROactive19).

J Clin Endocrinol Metab 2010 May 17;95(5):2163-71. Epub 2010 Mar 17.

Clinique d'Endocrinologie, Maladies Metaboliques, et Nutrition, Centre Hospitalier Universitaire de Nantes, Hôtel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France.

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http://dx.doi.org/10.1210/jc.2009-1974DOI Listing
May 2010
2 Reads
13 Citations
6.210 Impact Factor

Relation of inflammatory chemokines to insulin resistance and hypoadiponectinemia in coronary artery disease patients.

Eur J Intern Med 2009 Nov 6;20(7):712-7. Epub 2009 Sep 6.

Institute of Experimental and Clinical Medicine, University of Latvia, Pauls Stradins Clinical University Hospital, Riga, Latvia.

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http://dx.doi.org/10.1016/j.ejim.2009.08.004DOI Listing
November 2009
4 Reads
4 Citations
2.300 Impact Factor

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI.

BMC Med Genet 2009 Jul 14;10:63. Epub 2009 Jul 14.

Latvian Biomedical Research and Study Centre, Riga, Latvia.

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http://dx.doi.org/10.1186/1471-2350-10-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714840PMC
July 2009
4 Reads
6 Citations
2.083 Impact Factor

Interleukin-6 gene promoter -174G/C polymorphism and insulin resistance: a pilot study.

Clin Chem Lab Med 2007 ;45(9):1145-8

Institute of Experimental and Clinical Medicine, University of Latvia, Riga, Latvia.

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http://dx.doi.org/10.1515/CCLM.2007.260DOI Listing
January 2008
4 Reads
2.960 Impact Factor

Effects of pioglitazone in patients with type 2 diabetes with or without previous stroke: results from PROactive (PROspective pioglitAzone Clinical Trial In macroVascular Events 04).

Stroke 2007 Mar 8;38(3):865-73. Epub 2007 Feb 8.

Department of Cardiovascular Medicine, Queen's Medical Centre, University Hospital, Nottingham, UK.

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http://dx.doi.org/10.1161/01.STR.0000257974.06317.49DOI Listing
March 2007
14 Reads
68 Citations
5.723 Impact Factor

Microsatellite genotyping of chromosome 14q13.2-14q13 in the vicinity of proteasomal gene PSMA6 and association with Graves' disease in the Latvian population.

Immunogenetics 2004 Jul 17;56(4):238-43. Epub 2004 Jun 17.

Institute of Biology, University of Latvia, Miera iela 3, 2169 Salaspils, Latvia.

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http://dx.doi.org/10.1007/s00251-004-0687-9DOI Listing
July 2004
35 Reads
2 Citations
2.230 Impact Factor

Nitric oxide production and arachidonic acid metabolism in platelet membranes of coronary heart disease patients with and without diabetes.

Med Princ Pract 2003 Jan-Mar;12(1):10-6

Centre of Endocrinology, P Stradin's Clinical University Hospital, University of Latvia, Riga, Latvia.

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http://dx.doi.org/10.1159/000068154DOI Listing
May 2003
6 Reads
1 Citation
1.113 Impact Factor

Top co-authors

Janis Klovins
Janis Klovins

Latvian Biomedical Research and Study Centre

12
Andrejs Erglis
Andrejs Erglis

Pauls Stradins Clinical University Hospital

5
Davids Fridmanis
Davids Fridmanis

Latvian Biomedical Research and Study Centre

5
Aivars Lejnieks
Aivars Lejnieks

Riga Stradins University

4
Ilze Konrade
Ilze Konrade

Riga Stradins University

4
Ineta Kalnina
Ineta Kalnina

Latvian Biomedical Research and Study Centre

4
Vita Rovite
Vita Rovite

Latvian Biomedical Research and Study Centre

4
Gustavs Latkovskis
Gustavs Latkovskis

Pauls Stradi? Clinical University Hospital

4