Publications by authors named "Val J Lowe"

100Publications

Association of Cortical and Subcortical β-Amyloid With Standardized Measures of Depressive and Anxiety Symptoms in Adults Without Dementia.

J Neuropsychiatry Clin Neurosci 2020 Oct 22:appineuropsych20050103. Epub 2020 Oct 22.

Departments of Health Sciences Research (Krell-Roesch, Syrjanen, Rakusa, Kremers, Mielke, Vassilaki), Radiology (Vemuri, Lowe, Jack), Psychiatry and Psychology (Machulda), and Neurology (Mielke, Knopman, Petersen), Mayo Clinic, Rochester, Minn.; Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch); Department of Neurology, University Medical Center, Maribor, Slovenia (Rakusa); International Clinical Research Center, St. Anne Hospital, Brno, Czech Republic (Stokin); and Department of Neurology, Barrow Neurological Institute, Phoenix (Geda).

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http://dx.doi.org/10.1176/appi.neuropsych.20050103DOI Listing
October 2020

The evolution of parkinsonism in primary progressive apraxia of speech: A 6-year longitudinal study.

Parkinsonism Relat Disord 2020 Oct 7;81:34-40. Epub 2020 Oct 7.

Department of Neurology, Movement Disorders, Mayo Clinic, Rochester, MN, USA; Department of Neurology, Behavioral Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2020.09.039DOI Listing
October 2020

High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid- Distribution between Brain and Plasma.

J Pharmacol Exp Ther 2020 Nov 10;375(2):308-316. Epub 2020 Aug 10.

Department of Pharmaceutics and Brain Barriers Research Center (S.K.S., A.L.Z., K.M.A., K.K.K.) and Department of Experimental and Clinical Pharmacology (L.L.), University of Minnesota, College of Pharmacy, Minneapolis, Minnesota; Department of Pharmaceutical Sciences, College of Pharmacy, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois (K.M.A.); and Departments of Radiology (G.L.C., V.J.L.) and Neurology (G.L.C.), Mayo Clinic, College of Medicine, Rochester, Minnesota

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http://dx.doi.org/10.1124/jpet.120.265876DOI Listing
November 2020

Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderly.

Neurology 2020 04 26;94(17):e1793-e1802. Epub 2020 Mar 26.

From the Departments of Neurology (D.Z.C., E.K.S.L., B.F.B., M.M.M., D.S.K., R.C.P.), Radiology (C.G.S., V.J.L., A.R., C.R.J., P.V.), and Health Sciences Research (S.A.P., M.M.M.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000009315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274847PMC
April 2020

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults.

Neurology 2020 04 21;94(15):e1571-e1579. Epub 2020 Jan 21.

From the Departments of Radiology (E.M.A.-U., V.J.L., A.L.R., C.R.J., P.V.), Health Sciences Research (S.A.P., M.M.M.), Psychiatry and Psychology (M.M. Machulda), and Neurology (D.S.K., M.M. Mielke, R.C.P.), Mayo Clinic, Rochester, MN; and Department of Neurology (Y.E.G.), Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.1212/WNL.0000000000008979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251516PMC
April 2020

β-Amyloid PET and neuropathology in dementia with Lewy bodies.

Neurology 2020 01 20;94(3):e282-e291. Epub 2019 Dec 20.

From the Departments of Radiology (K.K., V.J.L., Q.C., C.G.S., C.R.J.), Health Sciences Research (S.A.P., T.G.L.), Information Technology (M.L.S., J.L.G.), Neurology (J.G.-R., D.T.J., D.S.K., R.C.P., B.F.B.), and Laboratory Medicine and Pathology (J.E.P.), Mayo Clinic, Rochester, MN; Department of Neurology (Q.C.), West China Hospital, Chengdu, Sichuan; and Departments of Neurology (N.G.-R.), Psychiatry and Psychology (T.J.F.), and Laboratory Medicine and Pathology (D.W.D., M.E.M.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000008818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108811PMC
January 2020

Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging.

Neurology 2020 01 4;94(2):e190-e199. Epub 2019 Dec 4.

From the Departments of Neurology (J.G.-R., A.A.R., R.D.B., M.M.M., D.S.K., R.C.P.), Health Sciences Research (T.L., J.G., J.A., S.A.P., M.M.M., W.K.), and Radiology (A.J.S., J.H., V.J.L., C.R.J., P.V., K.K.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000008735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988987PMC
January 2020

Radiation induced oxidation of [F]fluorothia fatty acids under cGMP manufacturing conditions.

Nucl Med Biol 2020 Jan - Feb;80-81:13-23. Epub 2019 Nov 9.

Department of Radiology, Mayo Clinic, Rochester, MN 55906, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2019.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056516PMC
November 2019

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.

Neurology 2019 07 30;93(1):e29-e39. Epub 2019 May 30.

From the Departments of Radiology (V.J.L., T.J.B., H.-K.M., P.F., M.L.S., M.K.P., K.K., D.T.J., P.V., C.G.S., C.R.J.), Health Sciences Research (H.J.W., S.D.W., T.M.T., M.M. Mielke, R.O.R.), Information Technology (M.L.S.), Neurology (B.F.B., K.A.J., D.T.J., J.G.-R., M.M. Mielke, D.S.K., R.C.P.), Neuroscience (M.E.M.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000007728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659005PMC
July 2019

Apolipoprotein A-I Crosses the Blood-Brain Barrier through Clathrin-Independent and Cholesterol-Mediated Endocytosis.

J Pharmacol Exp Ther 2019 06 10;369(3):481-488. Epub 2019 Apr 10.

Department of Pharmaceutics and Brain Barriers Research Center (A.L.Z., S.K.S., K.K.K.) and Department of Experimental and Clinical Pharmacology (L.L.), College of Pharmacy, University of Minnesota, Minneapolis, Minnesota; and Department of Radiology (G.L.C., V.J.L.) and Department of Neurology (G.L.C., J.F.P.), Mayo Clinic College of Medicine, Rochester, Minnesota

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http://jpet.aspetjournals.org/lookup/doi/10.1124/jpet.118.25
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http://dx.doi.org/10.1124/jpet.118.254201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538888PMC
June 2019

The influence of β-amyloid on [F]AV-1451 in semantic variant of primary progressive aphasia.

Neurology 2019 02 11;92(7):e710-e722. Epub 2019 Jan 11.

From the Departments of Radiology (J.L.W., C.G.S., I.S., M.L.S., C.R.J., V.J.L.), Health Science Research (Biostatistics) (P.R.M., S.D.W.), Neurology (Speech Pathology) (J.R.D., H.M.C., R.L.U.), Psychiatry and Psychology (M.M.M.), Neurology (Behavioral Neurology) (H.B., J.G.-R., D.T.J., B.F.B., D.S.K., R.C.P., K.A.J.), and Information Technology (M.L.S.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (N.E.-T.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000006913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382367PMC
February 2019

Amyloid- and tau-PET imaging in a familial prion kindred.

Neurol Genet 2018 Dec 3;4(6):e290. Epub 2018 Dec 3.

Department of Neurology (D.T.J., R.A.T., J.G.-R., H.B., D.S.K., R.C.P., B.F.B.) and Department of Radiology (D.T.J., C.R.J., V.J.L.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/NXG.0000000000000290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283453PMC
December 2018

Cerebral microbleeds: Prevalence and relationship to amyloid burden.

Neurology 2019 01 19;92(3):e253-e262. Epub 2018 Dec 19.

From the Departments of Neurology (J.G.-R., H.B., A.A.R., K.D.F., R.D.B., M.M.M., R.O.R., D.S.K., R.C.P.), Radiology (J.L.G., J.H., G.M.P., M.L.S., V.J.L., P.V., C.R.J., K.K.), and Health Sciences Research (S.A.P., T.L., M.M.M., R.O.R., W.K.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000006780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340386PMC
January 2019

Your brain scan may be a reflection of your genes.

Brain 2018 09;141(9):2539-2541

Department of Radiology, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1093/brain/awy226DOI Listing
September 2018

Non-right handed primary progressive apraxia of speech.

J Neurol Sci 2018 07 7;390:246-254. Epub 2018 May 7.

Department of Neurology (Behavioral Neurology), Mayo Clinic, Rochester, MN 55905, USA; Department of Neurology (Movement Disorders), Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986290PMC
July 2018

Brain structure and cognition 3 years after the end of an early menopausal hormone therapy trial.

Neurology 2018 04 21;90(16):e1404-e1412. Epub 2018 Mar 21.

From the Departments of Radiology (K.K., S.M.Z., V.J.L., J.L.G., M.L. Senjem, M.L. Settell, C.R.J.), Health Sciences Research (N.T., T.G.L., K.R.B., W.A.R.), Psychology and Psychiatry (J.A.F.), Internal Medicine (L.T.S.), Neurology (W.A.R.), and Surgery and Physiology and Biomedical Engineering (V.M.M.), Mayo Clinic, Rochester, MN; Department of Medicine (C.E.G., S.A.), School of Medicine and Public Health, University of Wisconsin and Geriatric Research, Education and Clinical Center, William S. Middleton Memorial, Veterans Hospital, Madison, WI; and Department of Biostatistics (N.M.D.), George Washington University, Washington, DC.

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http://dx.doi.org/10.1212/WNL.0000000000005325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902783PMC
April 2018

Joint associations of β-amyloidosis and cortical thickness with cognition.

Neurobiol Aging 2018 05 2;65:121-131. Epub 2018 Feb 2.

Mayo Clinic Alzheimer's Disease Research Center, Mayo Clinic and Foundation, Rochester, MN, USA; Department of Radiology, Mayo Clinic and Foundation, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871603PMC
May 2018

In vivo F-AV-1451 tau PET signal in mutation carriers varies by expected tau isoforms.

Neurology 2018 03 9;90(11):e947-e954. Epub 2018 Feb 9.

From the Departments of Neurology (D.T.J., D.S.K., J.G.-R., C.D., R.C.P., B.F.B.), Radiology (D.T.J., C.G.S., K.K., C.R.J., V.J.L.), Health Sciences Research (J.A.S.), and Information Technology (M.L.S.), Mayo Clinic, Rochester, MN; and Departments of Neurology (Z.W.) and Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000005117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858948PMC
March 2018

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia.

Neurology 2018 03 7;90(11):e940-e946. Epub 2018 Feb 7.

From the Departments of Neurology (H.B., W.G.M., J.G.-R., R.C.P., B.F.B., D.S.K., D.T.J.), Psychiatry and Psychology (M.M.M.), Radiology (S.A.P., H.J.W., M.L.S., C.R.J., D.T.J.), Pathology (J.E.P.), and Nuclear Medicine (V.J.L.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (M.E.M.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000005124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858947PMC
March 2018

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech.

Cortex 2018 02 2;99:358-374. Epub 2018 Jan 2.

Department of Neurology, Division of Behavioral Neurology, Mayo Clinic, Rochester, MN, USA; Department of Neurology, Division of Movement Disorders, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.cortex.2017.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800944PMC
February 2018

Novel GRN mutation presenting as an aphasic dementia and evolving into corticobasal syndrome.

Neurol Genet 2017 Dec 11;3(6):e201. Epub 2017 Dec 11.

Department of Neurology (H.B., R.C.P., D.S.K., B.F.B.), Department of Clinical Genomic and Neurology (R.H.G.), Department of Psychiatry and Psychology (M.A.M., J.A.F.), Department of Nuclear Medicine (V.J.W.), Department of Radiology (C.R.J.), and Alzheimer's Disease Research Center (C.M.D., D.J.G.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (N.A.F., R.R.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/NXG.0000000000000201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733247PMC
December 2017