Vajira H W Dissanayake

Vajira H W Dissanayake

UNVERIFIED PROFILE

Are you Vajira H W Dissanayake?   Register this Author

Register author
Vajira H W Dissanayake

Vajira H W Dissanayake

Publications by authors named "Vajira H W Dissanayake"

Are you Vajira H W Dissanayake?   Register this Author

63Publications

1053Reads

5Profile Views

The spectrum of deletions and duplications in the dystrophin (DMD) gene in a cohort of patients with Duchenne muscular dystrophy in Sri Lanka.

Neurol India 2019 May-Jun;67(3):714-715

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0028-3886.263235DOI Listing
February 2020

Strategies for Genomic Medicine Education in Low- and Middle-Income Countries.

Front Genet 2019 8;10:944. Epub 2019 Oct 8.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2019.00944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791921PMC
October 2019

The Frequency and Spectrum of Chromosomal Translocations in a Cohort of Sri Lankans.

Biomed Res Int 2019 2;2019:9797104. Epub 2019 Apr 2.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/bmri/2019/9797104/
Publisher Site
http://dx.doi.org/10.1155/2019/9797104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466940PMC
September 2019

Electrophoretic mobility shift assays implicate XRCC2:rs3218550C>T as a potential low-penetrant susceptibility allele for sporadic breast cancer.

BMC Res Notes 2019 Aug 1;12(1):476. Epub 2019 Aug 1.

Human Genetics Unit, Faculty of Medicine, University of Colombo, No. 25 Kynsey Road, Colombo 8, 00800, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13104-019-4512-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676616PMC
August 2019

'Hybrid Doctors' Can Fast Track the Evolution of a Sustainable e-Health Ecosystem in Low Resource Contexts: The Sri Lankan Experience.

Stud Health Technol Inform 2019 Aug;264:1356-1360

Department of Anatomy, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/SHTI190448DOI Listing
August 2019

Genotype data for single nucleotide polymorphism markers in sporadic breast cancer related genes in a Sri Lankan case-control cohort of postmenopausal women.

BMC Res Notes 2019 Jul 19;12(1):435. Epub 2019 Jul 19.

Human Genetics Unit, Faculty of Medicine, University of Colombo, No. 25 Kynsey Road, Colombo 8, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13104-019-4472-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642519PMC
July 2019

Genetics and genomic medicine in Sri Lanka.

Mol Genet Genomic Med 2019 Jun 20;7(6):e744. Epub 2019 May 20.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mgg3.744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565544PMC
June 2019

Relative normalized luciferase activity for the recombinant vector constructs carrying the ancestral and variant alleles for XRCC2:rs3218550 and PHB:rs6917.

BMC Res Notes 2018 Sep 4;11(1):643. Epub 2018 Sep 4.

Human Genetics Unit, Faculty of Medicine, University of Colombo, No. 25 Kynsey Road, Colombo 8, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13104-018-3760-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122654PMC
September 2018

Williams-Beuren syndrome in diverse populations.

Am J Med Genet A 2018 05;176(5):1128-1136

Medical Genetics Branch, National Human Genome Research Institute, The National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ajmg.a.38672
Publisher Site
http://dx.doi.org/10.1002/ajmg.a.38672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007881PMC
May 2018

Genetic determinants of sporadic breast cancer in Sri Lankan women.

BMC Cancer 2018 02 13;18(1):180. Epub 2018 Feb 13.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-018-4112-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809862PMC
February 2018

Focusing attention on ancestral diversity within genomics research: a potential means for promoting equity in the provision of genomics based healthcare services in developing countries.

J Community Genet 2017 Oct 11;8(4):275-281. Epub 2017 Jul 11.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12687-017-0311-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614882PMC
October 2017

The INSR rs2059806 single nucleotide polymorphism, a genetic risk factor for vascular and metabolic disease, associates with pre-eclampsia.

Reprod Biomed Online 2017 Apr 11;34(4):392-398. Epub 2017 Jan 11.

Discipline of Obstetrics and Gynaecology, School of Medicine and Robinson Research Institute, The University of Adelaide, Adelaide, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rbmo.2017.01.001DOI Listing
April 2017

Polymorphisms in the inflammatory pathway genes and the risk of preeclampsia in Sinhalese women.

J Matern Fetal Neonatal Med 2016 22;29(7):1072-6. Epub 2015 Apr 22.

a Discipline of Obstetrics and Gynaecology, School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide , Adelaide , Australia .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/14767058.2015.1034102DOI Listing
December 2016

Correspondence.

World J Pediatr 2016 08;12(3):374-375

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12519-016-0007-0DOI Listing
August 2016

Unsung heroes: Genomic successes in the developing world.

Appl Transl Genom 2016 Jun 17;9:1-2. Epub 2016 May 17.

Human Genetics Unit, Faculty of Medicine, Kynsey Road, Colombo 00800, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atg.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911427PMC
June 2016

Implementation of genomic medicine in Sri Lanka: Initial experience and challenges.

Appl Transl Genom 2016 Jun 17;9:33-6. Epub 2016 May 17.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atg.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911425PMC
June 2016

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

Pharmacogenet Genomics 2016 Jan;26(1):28-39

aTranslational Laboratory in Genetic Medicine, Agency for Science, Technology, and Research bSaw Swee Hock School of Public Health cNUS Graduate School for Integrative Sciences and Engineering dLife Sciences Institute Departments of eStatistics and Applied Probability fMedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore Departments of gParasitology hAnatomy, University of Colombo, Colombo, Sri Lanka iDepartment of Pediatrics, Division of Translational Therapeutics jCentre for Molecular Medicine and Therapeutics, Child and Family Research Institute kDepartment of Medicine, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890825PMC
January 2016

Novel AGXT gene mutation in a Sri Lankan family with primary Hyperoxaluria type 1.

Nephrology (Carlton) 2016 Jan;21(1):75-6

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nep.12572DOI Listing
January 2016

17p11.2 and Xq28 duplication detected in a girl diagnosed with Potocki-Lupski syndrome.

BMC Res Notes 2015 Sep 29;8:506. Epub 2015 Sep 29.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13104-015-1439-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588678PMC
September 2015

Novel COL4A3 gene mutations in a consanguineous family with autosomal recessive Alport syndrome.

Nephrology (Carlton) 2015 Aug;20(8):580

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nep.12430DOI Listing
August 2015

The obesity-related FTO gene variant associates with the risk of recurrent miscarriage.

Acta Obstet Gynecol Scand 2015 Jul 28;94(7):722-726. Epub 2015 Apr 28.

School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.12640DOI Listing
July 2015

Microbiome of the placenta in pre-eclampsia supports the role of bacteria in the multifactorial cause of pre-eclampsia.

J Obstet Gynaecol Res 2015 May 10;41(5):662-9. Epub 2014 Dec 10.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.12619DOI Listing
May 2015

Polymorphisms in the fibrinolytic pathway genes and the risk of recurrent spontaneous abortion.

Reprod Biomed Online 2014 Dec 16;29(6):745-51. Epub 2014 Sep 16.

School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rbmo.2014.08.014DOI Listing
December 2014

Polymorphism in the epidermal growth factor gene is associated with pre-eclampsia and low birthweight.

J Obstet Gynaecol Res 2014 May;40(5):1235-42

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.12362DOI Listing
May 2014

A Sri Lankan child with 48,XXXX syndrome.

Indian J Pediatr 2014 Feb 14;81(2):201-2. Epub 2013 Mar 14.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12098-013-0995-x
Publisher Site
http://dx.doi.org/10.1007/s12098-013-0995-xDOI Listing
February 2014

Clinical and genetic features of Huntington disease in Sri Lanka.

BMC Neurol 2013 Dec 5;13:191. Epub 2013 Dec 5.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2377-13-191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029274PMC
December 2013

Development and implementation of a web-based continuing professional development (CPD) programme on medical genetics.

J Telemed Telecare 2013 Oct;19(7):388-92

Health Education Bureau, Ministry of Health, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1357633X13506525DOI Listing
October 2013

Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population.

Indian J Hum Genet 2013 Oct;19(4):392-6

Department of Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo 00800, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0971-6866.124361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897131PMC
October 2013

Child with deletion 9p syndrome presenting with craniofacial dysmorphism, developmental delay, and multiple congenital malformations.

Case Rep Genet 2013 25;2013:785830. Epub 2013 Jul 25.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 08, 00800, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2013/785830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741698PMC
August 2013

Prevalence of chromosomal abnormalities in Sri Lankan women with primary amenorrhea.

J Obstet Gynaecol Res 2013 May 21;39(5):991-7. Epub 2012 Dec 21.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1447-0756.2012.02063.xDOI Listing
May 2013

Autosomal dominant hereditary ataxia in Sri Lanka.

BMC Neurol 2013 May 1;13:39. Epub 2013 May 1.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2377-13-39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667103PMC
May 2013

Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri-Lanka.

J Matern Fetal Neonatal Med 2013 Mar 21;26(5):532-6. Epub 2012 Nov 21.

Discipline of Obstetrics and Gynaecology, Robinson Institute, University of Adelaide, Adelaide, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/14767058.2012.743520DOI Listing
March 2013

An infant born to a mother with gestational diabetes presenting with 49,XXXXY syndrome and renal agenesis-a case report.

J Clin Res Pediatr Endocrinol 2012 Dec 2;4(4):223-5. Epub 2012 Oct 2.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4274/jcrpe.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537292PMC
December 2012

A case series of five sri lankan patients with ovotesticular disorder of sex development.

Clin Pediatr Endocrinol 2012 Oct 30;21(4):69-73. Epub 2012 Oct 30.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1297/cpe.21.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687650PMC
October 2012

Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women.

J Obstet Gynaecol Res 2012 Sep 30;38(9):1168-76. Epub 2012 Apr 30.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1447-0756.2012.01846.xDOI Listing
September 2012

The low frequency of Y chromosome microdeletions in subfertile males in a Sinhalese population of Sri Lanka.

Indian J Hum Genet 2012 Sep;18(3):320-5

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0971-6866.107985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656521PMC
September 2012

Haplotypes of heparin-binding epidermal-growth-factor-like growth factor gene are associated with pre-eclampsia.

J Obstet Gynaecol Res 2012 Jan 5;38(1):239-46. Epub 2011 Dec 5.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1447-0756.2011.01700.xDOI Listing
January 2012

A child with mosaicism for deletion (14)(q11.2q13).

Indian J Hum Genet 2012 Jan;18(1):130-3

Human Genetics Unit, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0971-6866.96684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385171PMC
January 2012

Y chromosome microdeletions are not associated with spontaneous recurrent pregnancy loss in a Sinhalese population in Sri Lanka.

Hum Reprod 2010 Dec 13;25(12):3152-6. Epub 2010 Oct 13.

Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/humrep/deq271DOI Listing
December 2010

A Sri Lankan child with 49,XXXXY syndrome.

Indian J Hum Genet 2010 Sep;16(3):164-5

Human Genetics Unit, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0971-6866.73413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009429PMC
September 2010

Ethical review, remit and responsibility in biomedical research in South Asia.

Indian J Med Ethics 2010 Apr-Jun;7(2):113-4

Department of Anthropology, Durham University, Durham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.20529/IJME.2010.042DOI Listing
May 2010

Prevalence of genetic thrombophilic polymorphisms in the Sri Lankan population--implications for association study design and clinical genetic testing services.

Exp Mol Pathol 2009 Oct 8;87(2):159-62. Epub 2009 Jul 8.

Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexmp.2009.07.002DOI Listing
October 2009

A study of three candidate genes for pre-eclampsia in a Sinhalese population from Sri Lanka.

J Obstet Gynaecol Res 2009 Apr;35(2):234-42

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1447-0756.2008.00926.xDOI Listing
April 2009

Morbidity and mortality associated with pre-eclampsia at two tertiary care hospitals in Sri Lanka.

J Obstet Gynaecol Res 2007 Feb;33(1):56-62

Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1447-0756.2007.00475.xDOI Listing
February 2007