Publications by authors named "Vahid Asnafi"

100Publications

Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.

J Exp Med 2020 Sep;217(9)

Université de Paris (Descartes), Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.1084/jem.20192360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478722PMC
September 2020

Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype.

Leukemia 2020 Jun 17. Epub 2020 Jun 17.

Service d'Hématologie Adultes, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris Descartes, 149-161 rue de Sèvres, 75015, Paris, France.

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http://dx.doi.org/10.1038/s41375-020-0900-3DOI Listing
June 2020

Arsenic trioxide (AsO) as a maintenance therapy for adult T cell leukemia/lymphoma.

Retrovirology 2020 03 21;17(1). Epub 2020 Mar 21.

Service d'Hématologie Adultes, Institut Imagine, Hôpital Universitaire Necker Enfants Malades, APHP, Université de Paris, 149-161 rue de Sèvres, 75743, Paris Cedex 15, France.

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http://dx.doi.org/10.1186/s12977-020-0513-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085150PMC
March 2020

Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow.

Cell Rep 2020 01;30(3):739-754.e4

INSERM UMR 1163, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, 75015 Paris, France; Paris Descartes - Sorbonne Paris Cité University, Imagine Institute, 75015 Paris, France; CNRS ERL 8254, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, 75015 Paris, France; Laboratory of Excellence GR-Ex, 75015 Paris, France.

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http://dx.doi.org/10.1016/j.celrep.2019.12.055DOI Listing
January 2020

CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia.

Cell Rep 2020 01;30(2):299-307.e3

Université Paris Descartes Sorbonne Cité, Institut Necker Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, Paris, France; Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades, Paris, France; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland; National Children's Research Centre, Children's Health Ireland at Crumlin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.12.026DOI Listing
January 2020

How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients?

Authors:
Francine Garnache-Ottou Chrystelle Vidal Sabeha Biichlé Florian Renosi Eve Poret Maïder Pagadoy Maxime Desmarets Anne Roggy Estelle Seilles Lou Soret Françoise Schillinger Sandrine Puyraimond Tony Petrella Claude Preudhomme Christophe Roumier Elisabeth A MacIntyre Véronique Harrivel Yohan Desbrosses Bérengère Gruson Franck Geneviève Sylvain Thepot Yuriy Drebit Thibaut Leguay François-Xavier Gros Nicolas Lechevalier Pascale Saussoy Véronique Salaun Edouard Cornet Zehaira Benseddik Richard Veyrat-Masson Orianne Wagner-Ballon Célia Salanoubat Marc Maynadié Julien Guy Denis Caillot Marie-Christine Jacob Jean-Yves Cahn Rémy Gressin Johann Rose Bruno Quesnel Estelle Guerin Franck Trimoreau Jean Feuillard Marie-Pierre Gourin Adriana Plesa Lucile Baseggio Isabelle Arnoux Norbert Vey Didier Blaise Romaric Lacroix Christine Arnoulet Blandine Benet Véronique Dorvaux Caroline Bret Bernard Drenou Agathe Debliquis Véronique Latger-Cannard Caroline Bonmati Marie-Christine Bene Pierre Peterlin Michel Ticchioni Pierre-Simon Rohrlich Anne Arnaud Stefan Wickenhauser Valérie Bardet Sabine Brechignac Benjamin Papoular Victoria Raggueneau Jacques Vargaftig Rémi Letestu Daniel Lusina Thorsten Braun Vincent Foissaud Jérôme Tamburini Hind Bennani Nicolas Freynet Catherine Cordonnier Magali Le Garff-Tavernier Nathalie Jacques Karim Maloum Damien Roos-Weil Didier Bouscary Vahid Asnafi Ludovic Lhermitte Felipe Suarez Etienne Lengline Frédéric Féger Giorgia Battipaglia Mohamad Mohty Sabrina Bouyer Ouda Ghoual Elodie Dindinaud Caroline Basle Mathieu Puyade Carinne Lafon Thierry Fest Mikael Roussel Xavier Cahu Elsa Bera Sylvie Daliphard Fabrice Jardin Lydia Campos Françoise Solly Denis Guyotat Anne-Cécile Galoisy Alice Eischen Caroline Mayeur-Rousse Blandine Guffroy Christian Recher Marie Loosveld Alice Garnier Vincent Barlogis Maria Alessandra Rosenthal Sophie Brun Nathalie Contentin Sébastien Maury Mary Callanan Christine Lefebvre Natacha Maillard Patricia Okamba Christophe Ferrand Olivier Adotevi Philippe Saas Fanny Angelot-Delettre Delphine Binda Eric Deconinck

Blood Adv 2019 12;3(24):4238-4251

University of Bourgogne Franche-Comté, INSERM, Établissement Français du Sang Bourgogne/Franche-Comté, Unite Mixte de Recherche (UMR) 1098, RIGHT (Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et Génique), Besançon, France.

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http://dx.doi.org/10.1182/bloodadvances.2019000647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929390PMC
December 2019

Clinical and biological features of PTPN2-deleted adult and pediatric T-cell acute lymphoblastic leukemia.

Blood Adv 2019 07;3(13):1981-1988

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.

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https://ashpublications.org/bloodadvances/article/3/13/1981/
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http://dx.doi.org/10.1182/bloodadvances.2018028993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616254PMC
July 2019

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.

Blood Adv 2019 02;3(3):461-475

Centre International de Recherche en Infectiologie, Université Lyon, Université Claude Bernard Lyon 1, INSERM, U1111, Centre National de la Recherche Scientifique, Unité Mixte de Recherche (UMR) 5308, Ecole Normale Supérieure de Lyon, Lyon, France.

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http://dx.doi.org/10.1182/bloodadvances.2018027508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373736PMC
February 2019

Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.

Clin Cancer Res 2019 04 18;25(8):2483-2493. Epub 2019 Jan 18.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de recherche Médicale (INSERM) U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1844DOI Listing
April 2019

A comprehensive catalog of LncRNAs expressed in T-cell acute lymphoblastic leukemia.

Leuk Lymphoma 2019 08 16;60(8):2002-2014. Epub 2019 Jan 16.

a Aix Marseille Univ, INSERM, TAGC , Marseille , France.

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http://dx.doi.org/10.1080/10428194.2018.1551534DOI Listing
August 2019

Intensified Therapy of Acute Lymphoblastic Leukemia in Adults: Report of the Randomized GRAALL-2005 Clinical Trial.

J Clin Oncol 2018 08 4;36(24):2514-2523. Epub 2018 Jun 4.

Françoise Huguet, Eric Delabesse, Institut Universitaire du Cancer, Toulouse; Sylvie Chevret, Nicolas Boissel, Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris Diderot; Agnès Buzyn, Vahid Asnafi, Elizabeth Macintyre, Hôpital Necker, AP-HP; Université Paris Descartes, Paris; Thibaut Leguay, Centre Hospitalier Universitaire, Pessac; Xavier Thomas, Véronique Lhéritier, Hôpital Lyon-Sud, Pierre Bénite; Martine Escoffre-Barbe, Centre Hospitalier Universitaire, Rennes; Patrice Chevallier, Marie C. Béné, Centre Hospitalier Universitaire, Nantes; Mathilde Hunault, Norbert Ifrah, Centre Hospitalier Universitaire, Angers; Norbert Vey, Institut Paoli-Calmettes, Marseille; Caroline Bonmati, Centre Hospitalier Universitaire, Nancy; Stéphane Lepretre, Centre Henri Becquerel, Rouen; Jean-Pierre Marolleau, Centre Hospitalier Universitaire, Amiens; Philippe Rousselot, Centre Hospitalier, Versailles; Jean-Yves Cahn, Centre Hospitalier Universitaire Grenoble-Alpes, La Tronche, France; Thomas Pabst, Inselspital; Swiss Group for Clinical Cancer Research, Bern; and Yves Chalandon, Swiss Group for Clinical Cancer Research, Bern; Hôpital Universitaire, Geneva, Switzerland.

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http://dx.doi.org/10.1200/JCO.2017.76.8192DOI Listing
August 2018

Novel Intergenically Spliced Chimera, , Is Associated with Aggressive T-ALL Biology and Outcome.

Mol Cancer Res 2018 03 12;16(3):470-475. Epub 2018 Jan 12.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, and Laboratory of Onco-Haematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0442DOI Listing
March 2018

Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia.

Blood Adv 2017 May 4;1(12):733-747. Epub 2017 May 4.

Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Radiobiologie Cellulaire et Moléculaire, Laboratoire des Cellules Souches Hématopoïétiques et Leucémiques, Equipe Labellisée Ligue Contre le Cancer, Unité Mixte de Recherche (UMR) 967 Stabilité génomique, cellules souches et radiations, Fontenay-aux-Roses, France.

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http://dx.doi.org/10.1182/bloodadvances.2017005538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728055PMC
May 2017

Early Response-Based Therapy Stratification Improves Survival in Adult Early Thymic Precursor Acute Lymphoblastic Leukemia: A Group for Research on Adult Acute Lymphoblastic Leukemia Study.

J Clin Oncol 2017 Aug 12;35(23):2683-2691. Epub 2017 Jun 12.

Jonathan Bond, Ludovic Lhermitte, Agata Cieslak, Amélie Trinquand, Elizabeth Macintyre, and Vahid Asnafi, Hôpital Necker-Enfants Malades; Jonathan Bond, Ludovic Lhermitte, Agata Cieslak, Amélie Trinquand, Elizabeth Macintyre, and Vahid Asnafi, Institut National de la santé et de la recherche médicale (INSERM) U1151; Hervé Dombret and Nicolas Boissel, University Hospital Saint-Louis, Paris; Diane Lara, Hospitalier de Versailles, Le Chesnay; Thomas Cluzeau, Centre Hospitalier Universitaire (CHU) de Nice, Nice; Thibaut Leguay, CHU de Bordeaux, Bordeaux; Cedric Pastoret, CHU de Rennes, Rennes; Mohamed Belhocine and Salvatore Spicuglia, Aix-Marseille University, Marseille; Véronique Lheritier, Centre Hospitalier Lyon Sud; Xavier Thomas, CHU de Lyon, Lyon; Stéphane Leprêtre, Centre Henri Becquerel and Université de Rouen Normandie, Rouen; Françoise Huguet, CHU de Toulouse, Toulouse; Norbert Ifrah, CHU d'Angers, Angers, France; and Carlos Graux, Godinne University Hospital, Yvoir, Belgium.

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http://dx.doi.org/10.1200/JCO.2016.71.8585DOI Listing
August 2017

Array-CGH predicts prognosis in plasma cell post-transplantation lymphoproliferative disorders.

Genes Chromosomes Cancer 2017 03 1;56(3):221-230. Epub 2016 Nov 1.

Service de Pathologie, Hôpital Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris (AP-HP), Université Paris Descartes Sorbonne Cité, Paris, France.

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http://dx.doi.org/10.1002/gcc.22428DOI Listing
March 2017

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.

Cancer Discov 2016 09 28;6(9):972-85. Epub 2016 Jun 28.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut national de recherche médicale (INSERM) U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0675DOI Listing
September 2016

CD1d-restricted peripheral T cell lymphoma in mice and humans.

J Exp Med 2016 05 11;213(5):841-57. Epub 2016 Apr 11.

CIRI, International Center for Infectiology Research, Université de Lyon, 69007 Lyon, France Institut National de la Santé et de la Recherche Médicale (INSERM), U1111, 69007 Lyon, France Ecole Normale Supérieure de Lyon, 69007 Lyon, France Université Lyon 1, Centre International de Recherche en Infectiologie, 69007 Lyon, France Centre National de la Recherche Scientifique (CNRS), UMR 5308, 69365 Lyon, France

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http://dx.doi.org/10.1084/jem.20150794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854725PMC
May 2016

An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.

Haematologica 2016 06 4;101(6):732-40. Epub 2016 Mar 4.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, and Laboratory of OncoHematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker EnfantsMalades, Paris

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http://dx.doi.org/10.3324/haematol.2015.141218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013941PMC
June 2016

Pediatric-Like Acute Lymphoblastic Leukemia Therapy in Adults With Lymphoblastic Lymphoma: The GRAALL-LYSA LL03 Study.

J Clin Oncol 2016 Feb 7;34(6):572-80. Epub 2015 Dec 7.

Stéphane Lepretre, Valérie Tallon-Simon, and Stéphanie Seris, Institut National de la Santé et de la Recherche Médicale (INSERM) U918, University of Rouen, Centre de Lutte contre le Cancer de Haute-Normandie (CLCC) H. Becquerel; Thomas Vermeulin and Jacques Benichou, Centre Hospitalier Universitaire (CHU) Charles Nicolle and INSERM U657, University of Rouen; Jean-Michel Picquenot, CLCC H. Becquerel, Rouen; Aurore Touzart, Vahid Asnafi, and Elizabeth Macintyre, University Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades, INSERM U1151, and Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades; Emmanuel Raffoux and Hervé Dombret, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot; Josette Brière, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris; Aline Tanguy-Schmidt and Norbert Ifrah, Maladies du sang CHU Angers, INSERM U892, and University of Angers, Angers; Gilles Salles, CHU Centre Hospitalier Lyon-Sud, Pierre Bénite; Thierry Lamy, CHU Ponchaillou, Rennes; Anne Moreau, Marie-Christine Béné, and Patrice Chevallier, CHU Hôtel-Dieu, Nantes; Françoise Huguet, CHU Purpan, Toulouse; Serge Bologna, CHU Vandoeuvre-les-Nancy, Vandoeuvre-les-Nancy; Réda Bouabdallah, CLCC P. Calmette, Marseille, France; and Carlos Graux, Godinne University Hospital, Yvoir, Belgium.

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http://ascopubs.org/doi/10.1200/JCO.2015.61.5385
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http://dx.doi.org/10.1200/JCO.2015.61.5385DOI Listing
February 2016

NAP1L1-MLLT10 is a rare recurrent translocation that is associated with HOXA activation and poor treatment response in T-cell acute lymphoblastic leukaemia.

Br J Haematol 2016 08 12;174(3):470-3. Epub 2015 Oct 12.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut national de recherche médicale (INSERM) U1151, Paris, France.

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http://dx.doi.org/10.1111/bjh.13772DOI Listing
August 2016

RUNX1 as a recombinase cofactor.

Oncotarget 2015 Sep;6(26):21793-4

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151, and Laboratory Paris (AP-HP), Hôpital Necker Enfants-Malades, Paris, France.

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http://dx.doi.org/10.18632/oncotarget.5488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673123PMC
September 2015

Targeting IRAK1 in T-cell acute lymphoblastic leukemia.

Oncotarget 2015 Aug;6(22):18956-65

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151 and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades, Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662467PMC
http://dx.doi.org/10.18632/oncotarget.4150DOI Listing
August 2015

Isolated flushes without permanent, fixed or other skin lesions in patients with systemic mastocytosis: a case series of 9 patients.

Eur J Dermatol 2015 Apr;25(2):182-4

Centre de Référence des Mastocytoses, AP-HP Necker-Enfants Malades, 156 Rue de Vaugirard, 75743 Paris, France, CNRS UMR 8147, Hôpital Necker-Enfants malades, Paris, France, Service de Médecine interne, Hôpital Tenon, Paris, France.

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http://dx.doi.org/10.1684/ejd.2014.2484DOI Listing
April 2015

HiJAKing T-ALL.

Authors:
Vahid Asnafi

Blood 2014 Nov;124(20):3038-40

INSTITUT NECKER ENFANTS-MALADES U1151.

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http://dx.doi.org/10.1182/blood-2014-09-600627DOI Listing
November 2014

Cryptic XPO1-MLLT10 translocation is associated with HOXA locus deregulation in T-ALL.

Blood 2014 Nov;124(19):3023-5

Université Sorbonne Paris Cité, Faculty of Medicine Descartes, Institut Necker-Enfants Malades, INSERM U1151, Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1182/blood-2014-04-567636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224197PMC
November 2014

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement.

J Exp Med 2014 Aug 18;211(9):1821-32. Epub 2014 Aug 18.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut national de recherche médicale (INSERM) U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, 75015 Paris, France

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http://dx.doi.org/10.1084/jem.20132585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144731PMC
August 2014

Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors.

PLoS One 2014 28;9(7):e103405. Epub 2014 Jul 28.

CNRS UMR8147, Paris Descartes University, Paris, France; Laboratory of Oncohematology, AP-HP, Necker Children's Hospital, INSERM U1151, Paris, France; INSERM U1163, CNRS ERL 8254, Laboratory of cellular and molecular basis of hematological disorders and their therapeutic implications, Imagine Institute, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103405PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113369PMC
December 2015

Peripheral blood 8 colour flow cytometry monitoring of hairy cell leukaemia allows detection of high-risk patients.

Br J Haematol 2014 Jul 25;166(1):50-9. Epub 2014 Mar 25.

Laboratoire d'Hématologie and CNRS UMR8147, Hôpital Necker - Enfants Malades, Université Paris Descartes, 149 rue de Sèvres, 75743, Paris Cedex 15, France; INSERM UMR1098, Université de Franche-Comté, EFS-B/FC Plateforme de BioMonitoring, 1 Bd Fleming, 25000, Besançon, France.

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http://dx.doi.org/10.1111/bjh.12839DOI Listing
July 2014

ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases.

PLoS One 2014 21;9(1):e85362. Epub 2014 Jan 21.

Centre de Référence des Mastocytoses, Faculté de Médecine et AP-HP Necker-Enfants Malades, Paris, France ; CNRS UMR 8147 and Institut Imagine, AP-HP, Hôpital Necker-Enfants Malades, Paris, France ; Service d'Hématologie Adulte, Université Paris Descartes, Paris Sorbonne Cité, Faculté de Médecine et AP-HP Necker-Enfants Malades, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085362PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897447PMC
October 2014

SET-NUP214 is a recurrent γδ lineage-specific fusion transcript associated with corticosteroid/chemotherapy resistance in adult T-ALL.

Blood 2014 Mar 21;123(12):1860-3. Epub 2014 Jan 21.

Université de Médecine Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France;

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http://dx.doi.org/10.1182/blood-2013-08-521518DOI Listing
March 2014

Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.

J Clin Oncol 2013 Dec 28;31(34):4333-42. Epub 2013 Oct 28.

Amélie Trinquand, Raouf Ben Abdelali, Etienne Lengliné, Noémie De Gunzburg, Ludovic Lhermitte, Jonathan Bond, Agnès Buzyn, Elizabeth Macintyre, and Vahid Asnafi, University Paris Descartes, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR)-8147, and Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades; Jérôme Lambert, UMR-S-717, Hôpital Saint-Louis, AP-HP; Kheira Beldjord, Etienne Lengliné, and Hervé Dombret, University Paris 7, Hôpital Saint-Louis, AP-HP, and Institut Universitaire d'Hématologie, EA3518, Paris; Aline Tanguy-Schmidt and Norbert Ifrah, Pôle de Recherche et d'Enseignement Supérieur L'Université Nantes Angers Le Mans, Centre Hospitalier Universitaire Angers Service des Maladies du Sang et L'Institut National de la Santé et de la Recherche Médicale (INSERM) U892, Angers; Dominique Payet-Bornet and Bertrand Nadel, Center of Immunology of Marseille Luminy, Aix-Marseille University, INSERM U1104 and Centre National de la Recherche Scientifique (CNRS) UMR-7280, Marseille; Hossein Mossafa, Laboratoire Cerba, Cergy-Pontoise; Véronique Lhéritier and Xavier Thomas, Centre Hospitalier Lyon Sud, Lyon; Françoise Huguet, Hôpital Purpan, Toulouse; Thibaud Leguay, Centre Hospitalier du Haut Lévêque, Pessac; Jean-Yves Cahn, UMR-5525 CNRS-Université Joseph Fourier, Grenoble; Caroline Bonmati, Centre Hospitalier Régional Hôpital de Brabois, Vandoeuvre Les Nancy; Sebastien Maury, Hôpital Henry Mondor, Creteil, France; Yves Chalandon, University Hospital of Geneva, Geneva, Switzerland; and André Delannoy, Hopital de Jolimont, La Louviere, Belgium.

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http://dx.doi.org/10.1200/JCO.2012.48.5292DOI Listing
December 2013

[Utility of 8-colours multiparameter flow cytometry immunophenotyping of plasma cells for the management of monoclonal gammopathy].

Ann Biol Clin (Paris) 2013 May-Jun;71(3):313-23

Laboratoire d'hématologie, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris AP-HP, Paris, France.

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http://dx.doi.org/10.1684/abc.2013.0813DOI Listing
February 2014

Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas.

Cancer Lett 2013 Jun 21;333(1):76-88. Epub 2013 Jan 21.

INSERM, U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), Team 4, Inflammation, Cancer, Cellules Souches Cancéreuses, Nice, France.

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http://dx.doi.org/10.1016/j.canlet.2013.01.020DOI Listing
June 2013

[Deciphering functional activity of TLX homeodomain oncogenes in T-ALL: a clue for a differentiating therapy?].

Med Sci (Paris) 2012 Aug-Sep;28(8-9):708-10. Epub 2012 Aug 22.

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http://dx.doi.org/10.1051/medsci/2012288012DOI Listing
October 2012

Dynamics of human prothymocytes and xenogeneic thymopoiesis in hematopoietic stem cell-engrafted nonobese diabetic-SCID/IL-2rγnull mice.

J Immunol 2012 Aug 13;189(4):1648-60. Epub 2012 Jul 13.

Laboratoire Développement du Système Immunitaire, Ecole Pratique des Hautes Etudes, Institut Universitaire d'Hématologie, Hôpital Saint-Louis, 75571 Paris, France.

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http://dx.doi.org/10.4049/jimmunol.1201251DOI Listing
August 2012

Erythroid leukemia evolving from multiple myeloma.

Blood 2012 Mar;119(11):2441

Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris, France.

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http://dx.doi.org/10.1182/blood-2011-07-366591DOI Listing
March 2012

Regulatory T-cell depletion in angioimmunoblastic T-cell lymphoma.

Am J Pathol 2010 Aug 21;177(2):570-4. Epub 2010 Jun 21.

Department of Hematology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.2353/ajpath.2010.100150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913366PMC
August 2010

Normal and pathological V(D)J recombination: contribution to the understanding of human lymphoid malignancies.

Adv Exp Med Biol 2009 ;650:180-94

Centre d'Immunologie de Marseille-Luminy, Université d'Aix Marseille, Marseille, France.

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http://dx.doi.org/10.1007/978-1-4419-0296-2_15DOI Listing
October 2009

Neuropilin-1 is not a marker of human Foxp3+ Treg.

Eur J Immunol 2009 Jun;39(6):1466-71

CNRS UMR 8147, Université Paris Descartes, Assistance Publique - Hôpitaux de Paris, Hôpital Necker, Paris, France.

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http://dx.doi.org/10.1002/eji.200839040DOI Listing
June 2009

TGF-beta induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation.

Blood 2009 Jun 30;113(26):6695-8. Epub 2009 Apr 30.

Laboratoire de Biologie Moléculaire de la Cellule, Unité Mixte de Recherche 5239, Centre National de la Recherche Scientifique, Ecole Normale Supérieure de Lyon, Institut Fédératif de Recherche 128 Biosciences Lyon Gerland, Lyon, France.

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http://dx.doi.org/10.1182/blood-2008-07-166835DOI Listing
June 2009

Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs.

Blood 2007 Oct 3;110(7):2324-30. Epub 2007 Jul 3.

The Université Paris V René Descartes, Institut National de la Santé et de la Recherche Médicale (INSERM) EMI0210 and Assistance Publique-Hôpitaux de Paris (AP-HP) Hôpital Necker-Enfants-Malades, Paris, France.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-04-07
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http://dx.doi.org/10.1182/blood-2007-04-079988DOI Listing
October 2007

Expression of T-lineage-affiliated transcripts and TCR rearrangements in acute promyelocytic leukemia: implications for the cellular target of t(15;17).

Blood 2006 Nov 20;108(10):3484-93. Epub 2006 Jul 20.

Department of Hematology, Université Paris-Descartes, Faculté de Médecine, and Institut National de la Santé et de la Recherche Médicale (INSERM) EMI0210, Assistance Publique-Hôpitaux de Paris (AP-HP) Necker-Enfants Malades, Paris, France.

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http://dx.doi.org/10.1182/blood-2005-09-009977DOI Listing
November 2006

Clinical impact of molecular diagnostics in low-grade lymphoma.

Best Pract Res Clin Haematol 2005 Mar;18(1):97-111

Biological Hematology, Hospital Necker-Enfants Malades, 149 Rue de Sevres, 75743 Paris Cedex 15, France.

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http://dx.doi.org/10.1016/j.beha.2004.08.005DOI Listing
March 2005

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy.

Blood 2004 Dec 30;104(13):4173-80. Epub 2004 Mar 30.

Necker-Enfants-Malades and Trousseau, Assistance Publique-Hopitaux de Paris, INSERM EMIU210 and Université Paris V, Hôpital Purpan, Toulouse, France.

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http://dx.doi.org/10.1182/blood-2003-11-3944DOI Listing
December 2004