Publications by authors named "Vadim Y Bolshakov"

46Publications

APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.

Neuron 2020 11 4;108(4):676-690.e8. Epub 2020 Sep 4.

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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November 2020

Mechanisms of fear learning and extinction: synaptic plasticity-fear memory connection.

Psychopharmacology (Berl) 2019 Jan 10;236(1):163-182. Epub 2018 Nov 10.

Department of Psychiatry, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, USA.

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January 2019

Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway.

Mol Neurodegener 2017 06 15;12(1):48. Epub 2017 Jun 15.

Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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June 2017

Diminishing fear: Optogenetic approach toward understanding neural circuits of fear control.

Pharmacol Biochem Behav 2018 11 11;174:64-79. Epub 2017 May 11.

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA. Electronic address:

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November 2018

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference.

J Neurosci 2015 Oct;35(40):13698-712

Laboratory of Genetic Neuropharmacology and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02215.

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October 2015

Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.

Neuron 2015 Mar;85(5):967-81

Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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March 2015

hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice.

Cell Stem Cell 2014 Nov 6;15(5):559-73. Epub 2014 Nov 6.

Molecular Neurobiology Laboratory, Department of Psychiatry and Program in Neuroscience, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA; Harvard Stem Cell Institute, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA. Electronic address:

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November 2014

Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation.

Stem Cells 2014 Jul;32(7):1789-804

Molecular Neurobiology Laboratory, Department of Psychiatry and Program in Neuroscience, McLean Hospital/Harvard Medical School, Belmont, Massachusetts, USA; Harvard Stem Cell Institute, McLean Hospital/Harvard Medical School, Belmont, Massachusetts, USA.

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July 2014

Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.

J Neurosci 2014 Mar;34(10):3653-67

Howard Hughes Medical Institute, Department of Cardiology, Boston Children's Hospital, Boston, Massachusetts 02115, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, and Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg 194223, Russia.

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March 2014

Synaptic encoding of fear extinction in mPFC-amygdala circuits.

Neuron 2013 Dec 27;80(6):1491-507. Epub 2013 Nov 27.

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA. Electronic address:

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December 2013

Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level.

Nat Commun 2013 ;4:1760

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA.

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November 2013

Learning and reconsolidation implicate different synaptic mechanisms.

Proc Natl Acad Sci U S A 2013 Mar 4;110(12):4798-803. Epub 2013 Mar 4.

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA.

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March 2013