Vaclav Zidek

Vaclav Zidek

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Vaclav Zidek

Vaclav Zidek

Publications by authors named "Vaclav Zidek"

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52Publications

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Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism.

Alcohol Clin Exp Res 2018 07 13;42(7):1177-1191. Epub 2018 Jun 13.

Department of Pharmaceutical Sciences , Skaggs School of Pharmacy & Pharmaceutical Sciences, University of Colorado, Aurora, Colorado.

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http://dx.doi.org/10.1111/acer.13763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028286PMC
July 2018

Systems genetic analysis of brown adipose tissue function.

Physiol Genomics 2018 01 10;50(1):52-66. Epub 2017 Nov 10.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , Aurora, Colorado.

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http://dx.doi.org/10.1152/physiolgenomics.00091.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866413PMC
January 2018

Downregulation of Gene Ameliorates Metabolic and Cardiac Traits in the Spontaneously Hypertensive Rat.

Hypertension 2017 06 10;69(6):1084-1091. Epub 2017 Apr 10.

From the Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic (F.L., O.Š., V.K., M.P.); Institute of Physiology (V.L., V.Z., P.M., J.Š., M.Š., M.P.) and Institute of Molecular Genetics (H.S.), Czech Academy of Sciences, Prague, Czech Republic; Institute for Experimental Medicine, Prague, Czech Republic (J.T., V.Š., L.K.); Department of Genetics, Cell Biology, and Development and Center for Genome Engineering, University of Minnesota, Minneapolis (C.G.S., D.F.V.); Max-Delbrück-Center for Molecular Medicine in the Hemholtz Society, Berlin, Germany (Z.I.); and Department of Molecular Medicine "Sapienza" University of Rome, Italy (M.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08798DOI Listing
June 2017

Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.

PLoS One 2016 31;11(3):e0152708. Epub 2016 Mar 31.

Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and the General Teaching Hospital, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152708PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816345PMC
August 2016

Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome.

Hypertension 2016 Feb 14;67(2):335-41. Epub 2015 Dec 14.

From the Department of Model Diseases, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic (M.P., V.Z., V.L., P.M., J.Š., M.Š.); Institute of Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic (V.K., J.K., J.Š.); Center of Experimental Medicine, Department of Metabolism and Diabetes, Institute for Clinical and Experimental Medicine, Prague, Czech Republic (V.Š., J.T., L.K.); and Department of Laboratory Medicine, University of California, San Francisco (T.K., J.W., T.W.K.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06158DOI Listing
February 2016

Transgenic rescue of defective Cd36 enhances myocardial adenylyl cyclase signaling in spontaneously hypertensive rats.

Pflugers Arch 2013 Oct 1;465(10):1477-86. Epub 2013 May 1.

Department of Cell Biology, Faculty of Science, Charles University in Prague, Vinicna 7, 128 44, Prague 2, Czech Republic.

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http://dx.doi.org/10.1007/s00424-013-1281-5DOI Listing
October 2013

Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan.

Am J Hypertens 2013 Jun 20;26(6):829-35. Epub 2013 Feb 20.

Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1093/ajh/hpt019DOI Listing
June 2013

Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat.

Basic Res Cardiol 2013 Jan 30;108(1):316. Epub 2012 Nov 30.

Department of Radiology, Oncology and Pathology, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1007/s00395-012-0316-yDOI Listing
January 2013

CobB1 deacetylase activity in Streptomyces coelicolor.

Biochem Cell Biol 2012 Apr 2;90(2):179-87. Epub 2012 Feb 2.

Institute of Microbiology of the Czech Academy of Sciences Vídenska 1083, Praha 4 14220, Czech Republic.

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http://dx.doi.org/10.1139/o11-086DOI Listing
April 2012

Generation of rat "supersonic" congenic/conplastic strains using superovulation and embryo transfer.

Methods Mol Biol 2010 ;597:267-75

Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic.

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http://dx.doi.org/10.1007/978-1-60327-389-3_18DOI Listing
February 2010

Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain.

Biochem Biophys Res Commun 2010 Jan 16;391(3):1348-51. Epub 2009 Dec 16.

Institute of Physiology and Center for Applied Genomics, Academy of Sciences of the Czech Republic, Vídenská 1083, 142 20 Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.bbrc.2009.12.050DOI Listing
January 2010

Hemodynamic characterization of recombinant inbred strains: twenty years later.

Hypertens Res 2008 Aug;31(8):1659-68

Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1291/hypres.31.1659DOI Listing
August 2008

Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat.

Hypertension 2008 Jan 10;51(1):148-53. Epub 2007 Dec 10.

Institute of Physiology and Center for Applied Genomics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.100743DOI Listing
January 2008

A new transgenic rat model of hepatic steatosis and the metabolic syndrome.

Hypertension 2005 May 4;45(5):1004-11. Epub 2005 Apr 4.

Department of Laboratory Medicine, University of California, San Francisco, USA.

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http://dx.doi.org/10.1161/01.HYP.0000161995.64192.2bDOI Listing
May 2005

A spontaneous mutation in the desmoglein 4 gene underlies hypotrichosis in a new lanceolate hair rat model.

Differentiation 2004 Dec;72(9-10):541-7

Gene Mapping Center, Max Delbruck Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1432-0436.2004.07209007.xDOI Listing
December 2004

Salt preference of congenic strains derived from the spontaneously hypertensive rat.

Physiol Behav 2004 Feb;80(5):617-22

Department of Physiology, University of Melbourne, Victoria, Melbourne 3010, Australia.

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http://dx.doi.org/10.1016/j.physbeh.2003.11.001DOI Listing
February 2004

Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat.

J Biol Chem 2003 Nov 27;278(46):45209-15. Epub 2003 Aug 27.

Institute of Physiology, Czech Academy of Sciences and the Center for Integrated Genomics, Prague 14220, Czech Republic.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M304869200
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http://dx.doi.org/10.1074/jbc.M304869200DOI Listing
November 2003

Genetic map of AFLP markers in the rat (Rattus norvegicus) derived from the H x B/Ipcv and B x H/Cub sets of recombinant inbred strains.

Biochem Genet 2003 Apr;41(3-4):77-89

Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Graduate School of Animal Health, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1023/a:1022069816135DOI Listing
April 2003

Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone.

J Biol Chem 2002 Dec 15;277(50):48501-7. Epub 2002 Oct 15.

Department of Laboratory Medicine, University of California, San Francisco, 94143, USA.

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http://dx.doi.org/10.1074/jbc.M206655200DOI Listing
December 2002