Publications by authors named "V S Nasim"

6 Publications

Levels of Mercury in Fish-Eating Children, With and Without Amalgam Restoration.

J Pharm Bioallied Sci 2019 May;11(Suppl 2):S397-S401

Department of Oral Pathology, Faculty of Dentistry, Asian Institute of Medicine, Science and Technology (AIMST) University, Kedah, Malaysia.

Background: Mercury is a naturally occurring metal that exists in three forms: elemental (metallic), inorganic, and organic mercury. Amalgam, which is an alloy of inorganic mercury, is used as a restorative material in dentistry. Organic mercury gets ingested in the body mainly by the consumption of seafood. Mercury is also stated to cause various adverse health effects such as gastrointestinal disturbances, dermatitis, muscle weakness, and neurological disorders. In recent years, the use of amalgam has become a controversy stating the various adverse effects of mercury. Hence, the study was conducted to determine and compare the variation in levels of organic and inorganic mercury in fish-eating children before and after placement of amalgam restoration.

Materials And Methods: Seventy-five subjects, 42 males (56%) and 35 females (44%) of age group ranging 7-13 years, living in South Canara district of Karnataka, India, were selected as a part of the study. Hair and urine samples were collected for estimation of organic and inorganic levels of mercury, respectively. Informed consent was collected from all the participating subjects.

Results: On comparison between organic and inorganic mercury levels during the study period, the concentration of organic mercury in hair samples was greater irrespective of amalgam restorations present (1.172 and 0.085, respectively; < 0.001).

Conclusion: Thus inorganic levels of mercury do not seem to pose a threat as much as the organic levels observed in hair, which remain fairly constant for a longer period of time. Hence in a coastal region where this study was undertaken and fish being a staple food, the risk could probably be attributed to more of an organic toxicity than an inorganic one. Thus amalgam is relatively safe to be practiced and the controversy against it should be reevaluated.
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May 2019

Evaluation of Cellular Phones for Potential Risk of Nosocomial Infection amongst Dental Operators and Auxiliary Staff.

J Int Oral Health 2015 Apr;7(4):51-3

Intern, King Khalid University, College of Dentistry, Abha, Kingdom of Saudi Arabia.

Background: This study evaluates cellular phones for potential risk of nosocomial infection amongst dental operators and auxiliary staff in a dental school.

Materials And Methods: Each participant's mobile phone was first cleaned with 70% isopropyl alcohol swab. Following the cleansing protocol, the partakers were asked to make a short phone call. The mobile phones were then washed aseptically by rotating damp cotton swabs with sterile normal saline. Bacterial growth was identified on sheep blood agar and McConkey's agar plates. Sabouraud dextrose agar media was used for fungi species. Descriptive statistics was established with the data statistically explored with SPSS version 17.0.

Results: About 50% of dental professionals had shown active bacterial and fungal growth in which 35% (n=35) were dental operators and 15% (n=15) were dental nurses. 53% Gram-positive organisms, 2% Gram-negative organisms, and 3% fungi were identified growths on cellular phones.

Conclusion: Thus, it can be concluded that the cellular phones of dental operators as compared to auxiliaries can act as a potential source of nosocomial infection.
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April 2015

Oral epidermoid cyst. A case report.

V S Nasim P Perumal

Eur J Paediatr Dent 2014 Jul;15(2 Suppl):247-9

Government Dental College, Thiruvananthapuram, Kerala, India.

Background: Paediatric epidermoid cysts are the rare lesions in the oral cavity, especially under the age of 10 years. They appear in the midline of the mouth usually as a result of residual ectodermal tissue of the first and second branchial arches, which fuse during the third and fourth weeks of intra-uterine life.

Case Report: We present a case of a male patient aged 8 years with swelling of the floor of the mouth, complaining of difficulty in swallowing. The ultrasonographic finding was infected ranula with a differential diagnosis of foregut duplication cyst and dermoid cyst. The cyst was surgically enucleated and was diagnosed as epidermoid cyst after histopathology. At the 18-month follow-up the cyst had not recurred.
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July 2014

Knowledge and Practice of Pulp Therapy in Deciduous Teeth among General Dental Practitioners in Saudi Arabia.

Ann Med Health Sci Res 2012 Jul;2(2):119-23

Department of Preventive Dental Sciences, Division of Pedodontics, King Khalid University College of Dentistry, Abha, Saudi Arabia.

Background: It has been observed that the general dentists and pedodontists differ in their treatment recommendations for pulp therapy in deciduous teeth.

Aim: To determine the knowledge and practice of pulp therapy in deciduous teeth by general dental practitioners (GDP) in two cities of southern Saudi Arabia.

Subjects And Methods: Fifty GDP selected at random from government and private dental clinics were questioned about pulp therapy in deciduous teeth in Abha and Najran cities using a 10-item questionnaire. The data were analyzed using IBM SPSS software version 11.0 and descriptive statistics were obtained.

Results: All 50 participants responded to the survey. Pulpotomy was suggested as the first line of treatment for pulp-exposed primary tooth by 32 respondents with 44 using Buckley's formocresol and 32 applying it on the pulp for 5 minutes. 43 respondents squeeze dried the cotton pellet before application on the pulp. In pulpectomy procedure 44 respondents preferred zinc oxide eugenol as obturation material with 22 using handheld reamers and 15 using slow-speed lentilospirals for obturation. 12 respondents used obturation techniques which had no scientific relevance. In order of preference Glass ionomer cement (GIC), silver amalgam, and stainless steel crowns were the materials of choice for final restoration of endodontically treated deciduous teeth. All 50 answered in the affirmative when asked if they would like to have additional information about pulp therapy in deciduous teeth.

Conclusion: The study concluded that general dentists were regularly performing pulp therapy in decidous teeth and therefore need to be frequently updated about these procedures.
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July 2012

The protective effect of Nigella sativa on lung injury of sulfur mustard-exposed Guinea pigs.

Exp Lung Res 2008 May;34(4):183-94

Department of Physiology and Pharmacological Research Center of Medicinal Plants, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.

The lung is one of the most exposable organs to chemical warfare agents such as sulfur mustard (SM) gas. Airway hyperresponsiveness and lung inflammation are reported in chemical warfare victims. There is no definite treatment for respiratory disorders induced by SM exposure. However, the protective effect of Nigella sativa on inflammatory process was shown. In the present study, the protective effect of Nigella sativa on tracheal responsiveness and lung inflammation of SM exposed guinea pigs was examined. Guinea pigs were exposed to diluent's solution (ethanol, control group), 100 mg/m(3) inhaled sulfur mustard (SME group), and SME treated with Nigella sativa, 0.08 g daily (SME+N), n = 6 for each group. Tracheal responsiveness (TR) to methacholine, total white blood cell (WBC) count of lung lavage, and differential WBC were done 14 days post exposure. The weigh of animal were measured at the beginning, middle (day 7), and the end (day 14) of the study. The TR of SM-exposed guinea pigs was significantly (P < .001) and WBC nonsignificantly higher than those of controls. In SME guinea pigs, there was a weight loss but in the case of SME+N guinea pigs, no obvious weight change thought the study was seen. The eosinophl, monocyte, and lympocytes in SME animals were significantly changed compared to control group (P < .001 for all cases). Monocyte, lymphocyte, and neutrophil number were decreased in SME+N group compared to SME animals, which was significant only for neutrophil (P < .05). These results showed a preventive effect of Nigella sativa on TR of SM-exposed guinea pigs.
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May 2008