Publications by authors named "V Gomathy Srividya"

3 Publications

  • Page 1 of 1

Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2.

Indian J Pediatr 2021 Nov 24. Epub 2021 Nov 24.

Department of Pediatric Cardiology, Institute of Child Health and Hospital for Children, Chennai, Tamil Nadu, India.

Objectives: To know the clinical presentation and outcome of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV- 2 (PIMS-TS) at a pediatric tertiary care center in Chennai.

Methods: Clinical and biochemical parameters of 65 children with PIMS-TS treated between July and October 2020 were studied. All children had their COVID RT-PCR and IgG COVID antibodies tests done.

Results: Mean age of the study group was 5.65 ± 3.68 y. Fever with red eyes, rash, vomiting, abdominal pain, and shock were common presenting features. Sixty percent of the study group had Kawasaki/incomplete Kawasaki features. Sixty-seven percent of the study group had coronary dilatation, 41% presented with shock, and 25% had left ventricular dysfunction. Coronary aneurysms were documented in 58% of the study group (z score more than 2.5). Respiratory presentation with pneumonia was seen in 10%. Four children presented with acute abdomen. Acute kidney injury, acute liver failure, hemolysis, pancytopenia, macrophage activation syndrome, encephalopathy, and multiorgan dysfunction syndrome (MODS) were other features. Forty-three percent required noninvasive oxygen support and 15.4% required mechanical ventilation. Intravenous immunoglobulin (73.8%) and methylprednisolone (49.8%) were used for therapy. Mortality in the study was 6%, which was due to MODS.

Conclusions: Acute febrile illness with mucocutaneous and gastrointestinal manifestations should have PIMS-TS as a possible differential diagnosis and needs evaluation with inflammatory markers and SARS-CoV-2 antibodies.
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November 2021

An Extemly Rare Case of Left Atrium and Right Pulmonary Vein Leiomyosarcoma.

J Clin Diagn Res 2015 Sep 1;9(9):ED18-20. Epub 2015 Sep 1.

Assistant Professor, Department of Pulmonology, Gayatri Vidyaparshid Instutite of Health Care and Medical Technology , Andhrapradesh, India .

We report a case of a 43-year-old female, presented with complaints of breathlessness for 1 month and had three episodes of syncopal attacks in the past two months. On clinical evaluation, bilateral pedal oedema was noticed. Echo cardiogram revealed large left atrial blood clot measuring 5.7x4.3x4.3 cm. Ultrasound whole abdomen was normal. We received an excised mass with right pulmonary vein end arterectomy speciemen. Histopathology of the mass revealed characteristic features of leiomyosarcoma with grade III, according to FNCCS grading system. The tumour was consistent with substantial amount of poorly differentiated fasicles of pleomorphic spindle cells and brisk atypical mitosis, with marked necrosis. Immunohistochemistry revealed the tumour cells in strong diffuse cytoplasmic positive for smooth muscle actin and Ki-67 showed 15-20% of tumour cells postivity. The prognosis depends on the individual tumour origin for individual site, size of tumour and depth of tumour than histological features. Pulmonary venous leiomyosarcomas were assumed to be misinterpretation of left atrial leiomyosarcomas with growth of the tumour into pulmonary vein lumen. We report this case in view of its extreme rarity.
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September 2015

Family planning practices prior to the acceptance of tubectomy: a study among women attending a maternity home in bangalore,india.

J Clin Diagn Res 2013 Aug 1;7(8):1640-3. Epub 2013 Aug 1.

Associate Professor, Department of Community Medicine, Rajarajeswari Medical College & Hospital , Mysore Road, Bangalore, India .

Introduction: The extent of acceptance of contraceptive methods still varies within societies. Reliance on sterilisation is appearing earlier in marriage and among ever-younger ages and lower parities.

Aim And Objective: To study the family planning practices adopted by women who undergo tubectomy before the acceptance of tubectomy.

Material And Methods: Cross-sectional study of tubectomy acceptors who attended a corporation referral maternity home in Bangalore, India by interview method using a pre-designed a pre-tested structured questionnaire.

Results: Majority 295(73.9%) of the study subjects had not practised any method of contraception before they underwent sterilisation. Increase in the education levels of the study subjects was associated with an increase in the contraceptive use (temporary methods) before they accepted tubectomy; this association was found to be statistically significant (p<0.0001).
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August 2013